Is total body fat more strongly correlated with lipid profile than the body mass index in type 2 diabetes?

2021 ◽  
Author(s):  
Chtioui Sara ◽  
Rafi Sanaa ◽  
Ghizlane El Mghari ◽  
Nawal El Ansari
Medicine ◽  
2017 ◽  
Vol 96 (39) ◽  
pp. e8126 ◽  
Author(s):  
Yiu-Hua Cheng ◽  
Yu-Chung Tsao ◽  
I-Shiang Tzeng ◽  
Hai-Hua Chuang ◽  
Wen-Cheng Li ◽  
...  

2017 ◽  
Vol 04 (01) ◽  
pp. e1-e4
Author(s):  
Gottfried Rudofsky ◽  
Tanja Haenni ◽  
John Xu ◽  
Eva Johnsson

Abstract Genital infections are associated with sodium glucose co-transporter 2 inhibitors such as dapagliflozin. Since patients with Type 2 diabetes are at increased risk of genital infections, and obesity is a risk factor for infections, obese patients with Type 2 diabetes could be more susceptible to genital infections when treated with sodium glucose co-transporter 2 inhibitors. This pooled dataset assessed the frequency of genital infections according to baseline body mass index in patients treated with dapagliflozin 10 mg. Data were pooled from 13 studies of up to 24 weeks’ duration (dapagliflozin N=2 360; placebo N=2 295). Frequency of genital infections was compared between three body mass index subgroups (<30, ≥30−< 35 and ≥35 kg/m2). Genital infections were reported in 130 (5.5%) patients receiving dapagliflozin and 14 (0.6%) patients receiving placebo; none of which were serious. Genital infections were more common in women (84/130 [64.6%]) than in men (46/130 [35.4%]) treated with dapagliflozin. In the body mass index < 30, ≥ 30−< 35 and ≥ 35 kg/m2 dapagliflozin-treated subgroups, 38/882 (4.3%), 47/796 (5.9%) and 45/682 (6.6%) patients presented with genital infections, respectively. Although the frequency was low overall and relatively similar between subgroups, there was a trend towards an increase in genital infections in patients with a higher body mass index. This trend is unlikely to be clinically relevant or to affect suitability of dapagliflozin as a treatment option for obese patients with Type 2 diabetes, but rather should influence advice and counselling of overweight patients on prevention and treatment of genital infections.


2020 ◽  
Vol 51 (6) ◽  
pp. 564-571 ◽  
Author(s):  
Jorge Escobedo-de la Peña ◽  
Jorge Alejandro Ramírez-Hernández ◽  
María Teresa Fernández-Ramos ◽  
Evangelina González-Figueroa ◽  
Beatriz Champagne

2006 ◽  
Vol 904 (1) ◽  
pp. 420-423 ◽  
Author(s):  
ROGER M. SIERVOGEL ◽  
L. MICHELE MAYNARD ◽  
WAYNE A. WISEMANDLE ◽  
ALEX F. ROCHE ◽  
SHUMEI S. GUO ◽  
...  

2021 ◽  
Vol 8 (2) ◽  
pp. 106-109
Author(s):  
Tejashwini V B ◽  
Ganashree C P

Obesity is defined as increased accumulation of fat in various tissues in the body causes impairment in the body. The cause for obesity is imbalance between calories intake and calories expenditure There is increased intake of calorie rich foods and reduced physical activity due to urbanization all over the world.Body mass index is simple index to divide obesity among adults. It is defined as person’s weight in kilograms divided by height in meter squares (m).Obesity and elevated BMI are the major causes for development of chronic diseases like stroke, hypertension, malabsorption syndrome, Type 2 diabetes and other cardiovascular disorders.BMI and obesity are the modifiable risk factors of type 2 diabetes, cardiovascular disorders and hypertension. This study was carried out to correlate the relationship between BMI and lipid profile among young healthy medical students. This study comprises 45 males and 55 females (100 in total) young adults aged between 18 to 25 years. The design for this study was cross-sectional survey. Ethical approval was taken from ethical committee of BMCH, Chitradurga. BMI, lipid profile levels are measured from the subjects. A total of 100 participants were tested. Among them 45 males were males and 55 were females. The mean age of the subjects was 22 years. Among them, 30 were overweight and 17 were obese while, 4 were underweight. The mean BMI was 26.72±3.45 Kg/m. Mean serum cholesterol in 100 students was 147.63 ± 15 mg/dl, mean LDL-C was 85.23±14.8 mg/dl, mean HDL-C was 23.22±5.56 mg/dl and mean triglycerides were 76.6 ±18.5 mg/dl. The mean BMI of students was 22.5 kg/m ±5.5.It was found in our study that prevalence of overweight is the major driving forces in the development of diabetes mellitus, hypertension, metabolic syndrome. Prevalence of obesity is significantly higher among young adults. This prevalence may be due to lack of awareness and unhealthy lifestyles, so health education and more preventive measures should decrease the prevalence of obesity and cardiac risks in our medical college by modifying their lifestyle.


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