Hypopituitarism in young patients: clinical aspects and diagnosis

2021 ◽  
Author(s):  
Faten Hadj Kacem ◽  
Oumeyma Trimeche ◽  
Salah Dhoha Ben ◽  
Hamdi Frikha ◽  
Mahdi Chaabouni ◽  
...  
Keyword(s):  
Young Patients ◽  
Clinical Aspects

scholarly journals Hypertensive retinopathy: clinical aspects

HYPERTENSION ◽  
2021 ◽  
Vol 14 (3) ◽  
pp. 17-23
Author(s):  
N.Ya. Dotsenko ◽  
I.A. Shekhunova ◽  
S.S. Boev ◽  
L.V. Нerasуmenko ◽  
A.V. Molodan ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Arterial Hypertension ◽  
Prognostic Value ◽  
Prognostic Significance ◽  
Young Patients ◽  
Small Diameter ◽  
Scientific Data ◽  
Clinical Aspects ◽  
Hypertensive Retinopathy ◽  
Routine Practice

Funduscopic examination has long been recognized as the most affordable way to assess the condition of small diameter vessels. However, accumulation of new research data, changes in the requirements for the management of patients with various diseases require a return to the clinical, prognostic significance of fundoscopy and the specification of indications for its conduction in certain situations. This article discusses the prevalence of retinopathy depending on the etiological factor, criteria and stages of its development. Until now, a number of issues regarding retinopathy have not been finally resolved, in particular the classification optimal for routine practice, method of its study, etc. It is believed that changes in the fundus blood vessels reflect parallel changes in the vessels of other regions, but this is not always so. A moderate prognostic value of “mild” retinopathy has been established in terms of the risk of cardiovascular diseases, with moderate retinopathy, this relationship reaches a strong level, and with a malignant one, there is a strong correlation with death. The article discusses indications for fundoscopy in routine clinical practice, taking into account the latest scientific data and international recommendations. For the treatment of hypertensive retinopathy, only adequate control of blood pressure is recommended, which can reduce the signs of retinopathy. The authors concluded that the prognostic value of stage 1–2 hypertensive retinopathy is minimal and does not affect patient management. The latter eliminates the need for fundoscopy in patients with mild, controlled arterial hypertension, not suffering from diabetes, with the exception of young patients. Fundoscopy is required in patients with difficult-to-control and resistant arterial hypertension, high variability of blood pressure.

scholarly journals Post-spinal anesthesia headache: a literature review

2021 ◽  
Author(s):  
Rafaela Seixas Pinho ◽  
Gabriel Aranha Sousa Maués ◽  
Paola Bitar de Mesquita Abinader ◽  
Sérgio Beltrão de Andrade Lima
Keyword(s):  
Literature Review ◽  
Spinal Anesthesia ◽  
Young Patients ◽  
Relevant Information ◽  
Influential Factors ◽  
Clinical Aspects ◽  
Neck Stiffness ◽  
Modifiable Factors ◽  
Great Relevance ◽  
Orthostatic Position

Background: Headache is the most common neurological symptom and is an important complication of cerebrospinal fluid access (CSF) techniques, reported by 1/3 of the patients after 48 hours of puncture. Objective: Present the most relevant information about the clinic and influential factors of headache after spinal anesthesia. Method: A literature review was conducted in pubmed, Scielo, Lilacs and Google academic databases, having as inclusion criteria articles of great relevance published in English, Portuguese and Spanish in the period 2016 to 2021 and exclusion criteria articles published outside that period. Results: Post-spinal anesthesia headache or post-dural puncture headache (DPC) belongs to the group of secondary headaches resulting from nonvascular disorders. The condition is composed of headache in the occipital and frontal region, which worsens in orthostatic position and may be accompanied by other symptoms such as neck stiffness, hearing disorders, photophobia, and nausea. The incidence of headache after the procedure varies according to the technique used, which can be medial or para - medial; more frequent in females; with the use of calibrated needles and in young patients. Regarding the recovery time, according to the reviewed literature, 72% of the patients had resolved the case within 7 days. Conclusion: Therefore, the correct performance of the procedure, with attention to modifiable factors, and the careful evaluation of clinical aspects for early diagnosis are essential to reduce the incidence and morbidity of this potentially disabling headache.

Chronic headache in young patients: clinical aspects and treatment suggestions

2003 ◽  
Vol 24 (S2) ◽  
pp. s112-s114 ◽  
Author(s):  
L. Grazzi ◽  
S. Usai ◽  
G. Bussone
Keyword(s):  
Chronic Headache ◽  
Young Patients ◽  
Clinical Aspects

Pseudotumor Cerebri dell'età infantile e adolescenziale

2003 ◽  
Vol 16 (3) ◽  
pp. 497-501
Author(s):  
A. Erbetta ◽  
M. Estienne ◽  
F. Zibordi ◽  
MR Balestrini ◽  
L. Chiapparini ◽  
...  
Keyword(s):  
Young Patients ◽  
Pseudotumor Cerebri ◽  
Clinical Aspects ◽  
Csf Pressure

In a retrospective fashion we reviewed the clinical aspects and the neuroradiological findings in 23 young patients (mean age at the onset 9.2 year-old) affected by Pseudotumor Cerebri, examinated at our Institution in the last ten years. The syndrome is characterized by high CSF pressure value without hydrocephalus, expansive lesions or biochemical modifications of the liquor. The aim of this study is to evaluate the importance of the neuroradiological examinations in the diagnosis of Pseudotumor Cerebri.

Relation Between Age and Head and Neck Cancer Recurrence after Surgery: A Multivariate Analysis

1995 ◽  
Vol 113 (3) ◽  
pp. 197-203 ◽  
Author(s):  
Peter G. Von Doersten ◽  
Raul M. Cruz ◽  
Barry M. Rasgon ◽  
Charles P. Quesenberry ◽  
Raymond L. Mlsinger
Keyword(s):  
Multivariate Analysis ◽  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Young Patients ◽  
Biomedical Literature ◽  
Future Research ◽  
Clinical Aspects ◽  
Upper Aerodigestive Tract ◽  
Old Patients

Recent reports have described an increase in squamous cell carcinoma of the upper aerodigestive tract in young adults. As the preponderance of epidemiologic data exists for the population between 50 and 70 years of age, controversy has developed regarding the clinical course of head and neck cancer in youth. Some authors advocate more aggressive management, calling attention to the lack of “classic” predisposing factors and suggesting genetic disorders or Immunodeficiency. Basic science researchers have reported greater DNA fragility, sensitivity to carcinogens, and altered immune responses in young patients with carcinoma. To further elucidate the clinical aspects of this controversy, we performed a retrospective review using multivariate analysis to determine factors that affect recurrence. After screening 820 charts, 155 patients were found who met strict entrance criteria to the study. The patients were separated into five age groups, and 16 clinical variables were collected on each patient. Cox proportional hazards modeling revealed no significantly higher likelihood of recurrence in the 15- to 39-year-old age group. The model did find that metastatic adenopathy was predictive of recurrence ( p = 0.034). The overall model further suggested a trend toward higher relative risk of recurrence in the middle-aged groups ( p = 0.0541). In our review of the English biomedical literature, this is the first study to directly compare the outcome of young head and neck cancer patients with that of old patients using multivariate analysis. Future research is indicated in developing precise outcome predictions according to TNM staging, aneuploidy status, and DNA fragility In young patients. Efforts at limiting carcinogen exposure Should continue.

scholarly journals Genital prolapse at university hospital of Cocody: clinical aspects and therapeutic management

2018 ◽  
Vol 7 (5) ◽  
pp. 1673
Author(s):  
Charles Kakou ◽  
Roland Adjoby ◽  
Raoul Kasse ◽  
Victorine Assuikwe ◽  
Boston Mian ◽  
...  
Keyword(s):  
Uterine Prolapse ◽  
Young Patients ◽  
Genital Prolapse ◽  
University Hospital ◽  
Therapeutic Management ◽  
Clinical Aspects ◽  
Gynecology And Obstetrics ◽  
One Year ◽  
Descriptive Purpose ◽  
The University

Background: To determine the epidemiological aspects of genital prolapse; to describe the different clinical aspects of genital prolapse observed and to evaluate the therapeutic management of genital prolapse at the University hospital of Cocody (UH-C).Methods: We did an observational and transversal study with a descriptive purpose over 5 years from 2012 to 2016 in the Gynecology and obstetrics department of UH-C. The studied population was all cases of genital prolapse diagnosed and treated in the service during the period of the study. A follow-up over one year after surgery has been observed to evaluate surgical outcomes and recurrences. Genital prolapse was generally a uterine prolapse at stage 3 or 4. It was associated to cystocele in 31.4%. We did not find stress urinary incontinence associated with prolapse in our study. The surgical intervention performed was, in the majority case, the triple perineal intervention with success of 95.6%. A case of recurrence in the form of cystocele has been observed to a year of decline.Results: Genital prolapse was relatively common. It accounted for 0.5% of all gynecological visits. Women were young with an average age of 39.5 years. 62.9% were multiparous. 62.5% had given birth at least once at home without medical assistance. The reason for consultation the most watched was the projection of body at the vulva.Conclusions: Genital prolapse is a condition under estimated in Côte d'Ivoire. It represented 0.5% of the gynecological visits. Obstetric traumas were frequently found in our young patients with genital prolapse. The sociocultural considerations have contributed to delay consultations, to observe very advanced stages. The surgery performed was mainly the perineal triple surgery.

scholarly journals Clinical Aspects of Phacovitrectomy Complications

2018 ◽  
Vol 15 (2S) ◽  
pp. 140-144
Author(s):  
D. V. Pronichkin ◽  
O. L. Fabrikantov ◽  
D. M. Misyurev
Keyword(s):  
Young Patients ◽  
Early Postoperative Period ◽  
Clinical Aspects ◽  
Visual Rehabilitation ◽  
Epiretinal Membranes ◽  
Lens Position ◽  
Macular Holes ◽  
Vitreous Opacities ◽  
Iol Power ◽  
Length Changes

In recent years, the incidence of vitreoretinal pathology has increased both in elderly and young patients. Such types of vitreoretinal pathology as macular holes, epiretinal membranes and vitreous opacities of various genesis require surgical intervention (vitrectomy) that may lead to cataract in the early postoperative period. Moreover, in elderly patients vitreoretinal diseases and cataract frequently accompany each other. From this, the necessity arises to perform phacovitrectomy. This procedure takes more time and is more technically complicated however, it is well tolerated by patients. There are several benefits of phacovitrectomy when complex ocular pathology, e.g., optimized visualization of the posterior segment, decreased amount of total surgical procedures, faster visual rehabilitation, and reduced risks and costs associated with a second surgery. However, some complications may still occur. The most common complications are posterior capsule opacification, increased postoperative inflammation, early postoperative IOP rising, and refractive errors. Numerous studies have described a mismatch between the expected postoperative refraction according to preoperative calculations and the actually achieved refraction. Most studies report about a negative refractive error. Various explanations have been suggested, including the biometry for measuring the axial length, changes in the effective lens position, IOL type, the formula used to calculate IOL power, the use of gas tamponade, and the type of macular pathology.

Clinical aspects of reactive oxygen and nitrogen species

2004 ◽  
Vol 71 ◽  
pp. 121-133 ◽  
Author(s):  
Ascan Warnholtz ◽  
Maria Wendt ◽  
Michael August ◽  
Thomas Münzel
Keyword(s):  
Oxidative Stress ◽  
Reactive Oxygen Species ◽  
Risk Factor ◽  
Endothelial Dysfunction ◽  
Vascular Tissue ◽  
Rapid Development ◽  
Reactive Oxygen ◽  
Clinical Aspects ◽  
No Production ◽  
Oxygen Species

Endothelial dysfunction in the setting of cardiovascular risk factors, such as hypercholesterolaemia, hypertension, diabetes mellitus and chronic smoking, as well as in the setting of heart failure, has been shown to be at least partly dependent on the production of reactive oxygen species in endothelial and/or smooth muscle cells and the adventitia, and the subsequent decrease in vascular bioavailability of NO. Superoxide-producing enzymes involved in increased oxidative stress within vascular tissue include NAD(P)H-oxidase, xanthine oxidase and endothelial nitric oxide synthase in an uncoupled state. Recent studies indicate that endothelial dysfunction of peripheral and coronary resistance and conductance vessels represents a strong and independent risk factor for future cardiovascular events. Ways to reduce endothelial dysfunction include risk-factor modification and treatment with substances that have been shown to reduce oxidative stress and, simultaneously, to stimulate endothelial NO production, such as inhibitors of angiotensin-converting enzyme or the statins. In contrast, in conditions where increased production of reactive oxygen species, such as superoxide, in vascular tissue is established, treatment with NO, e.g. via administration of nitroglycerin, results in a rapid development of endothelial dysfunction, which may worsen the prognosis in patients with established coronary artery disease.

Advocating for Insurance for Young Patients

ASHA Leader ◽  
2004 ◽  
Vol 9 (3) ◽  
pp. 3-23
Author(s):  
Katrina Zeit
Keyword(s):  
Young Patients
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