SULFATION PATHWAYS: Sources and biological activities of marine sulfated steroids
2018 ◽
Vol 61
(2)
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pp. T211-T231
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Keyword(s):
Marine environment is rich in structurally unique molecules and can be an inspiring source of novel drugs. Currently, six marine-derived drugs are in the market with FDA approval and several more are in the clinical pipeline. Structurally diverse and complex secondary metabolites have been isolated from the marine world and these include sulfated steroids. Biological activities of nearly 150 marine sulfated steroids reported from 1978 to 2017 are compiled and described, namely antimicrobial, antitumor, cardiovascular and antifouling activities. Structure–activity relationship for each activity is discussed.
2015 ◽
Vol 97
◽
pp. 419-443
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2016 ◽
Vol 25
(5)
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pp. 819-823
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2018 ◽
Vol 11
(5)
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pp. 278
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2010 ◽
Vol 65
(11)
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pp. 1381-1383
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2016 ◽
Vol 8
(9)
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pp. 150
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2020 ◽
Vol 20
(1)
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pp. 12-23
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2015 ◽
Vol 25
(1)
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pp. 109-115
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2014 ◽
Vol 111
(03)
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pp. 429-437
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