Custom-made Supplement Server : Digitally Resolve Nutritional Deficiencies

2019 ◽  
Vol 139 (5) ◽  
pp. 308-311
Author(s):  
Yoshiki KANAI ◽  
Yuta KAKIMI ◽  
Ryogo KUBO
Keyword(s):  
Nutritional Deficiencies ◽  
Custom Made

Origin of Hepatic Nuclear Inclusion Bodies

1973 ◽  
Vol 31 ◽  
pp. 426-427
Author(s):  
F. G. Zaki ◽  
J. A. Greenlee ◽  
C. H. Keysser
Keyword(s):  
Inclusion Bodies ◽  
Storage Disease ◽  
Glycogen Storage ◽  
Nutritional Deficiencies ◽  
Nuclear Inclusion ◽  
Electron Microscopic ◽  
Human Liver Cells ◽  
Microscopic Studies ◽  
Per Se ◽  
Experimental Liver

Nuclear inclusion bodies seen in human liver cells may appear in light microscopy as deposits of fat or glycogen resulting from various diseases such as diabetes, hepatitis, cholestasis or glycogen storage disease. These deposits have been also encountered in experimental liver injury and in our animals subjected to nutritional deficiencies, drug intoxication and hepatocarcinogens. Sometimes these deposits fail to demonstrate the presence of fat or glycogen and show PAS negative reaction. Such deposits are considered as viral products.Electron microscopic studies of these nuclei revealed that such inclusion bodies were not products of the nucleus per se but were mere segments of endoplasmic reticulum trapped inside invaginating nuclei (Fig. 1-3).

Efficacy of Adding Folic Acid to Foods

2012 ◽  
Vol 82 (3) ◽  
pp. 177-186 ◽  
Author(s):  
Violeta Fajardo ◽  
Gregorio Varela-Moreiras
Keyword(s):  
Folic Acid ◽  
Age Groups ◽  
Nutritional Deficiencies ◽  
Physiological Status ◽  
Food Fortification ◽  
Limited Information ◽  
Dietary Recommendations ◽  
Nutritional Education ◽  
Food Composition Tables ◽  
Staple Foods

In the past, food fortification along with nutritional education and the decrease in food costs relative to income have proven successful in eliminating common nutritional deficiencies. These deficiencies such as goiter, rickets, beriberi, and pellagra have been replaced with an entirely new set of “emergent deficiencies” that were not previously considered a problem [e.g., folate and neural tube defects (NTDs)]. In addition, the different nutrition surveys in so-called affluent countries have identified “shortfalls” of nutrients specific to various age groups and/or physiological status. Complex, multiple-etiology diseases, such as atherosclerosis, diabetes, cancer, and obesity have emerged. Food fortification has proven an effective tool for tackling nutritional deficiencies in populations; but today a more reasonable approach is to use food fortification as a means to support but not replace dietary improvement strategies (i. e. nutritional education campaigns). Folic acid (FA) is a potential relevant factor in the prevention of a number of pathologies. The evidence linking FA to NTD prevention led to the introduction of public health strategies to increase folate intakes: pharmacological supplementation, mandatory or voluntary fortification of staple foods with FA, and the advice to increase the intake of folate-rich foods. It is quite contradictory to observe that, regardless of these findings, there is only limited information on food folate and FA content. Data in Food Composition Tables and Databases are scarce or incomplete. Fortification of staple foods with FA has added difficulty to this task. Globally, the decision to fortify products is left up to individual food manufacturers. Voluntary fortification is a common practice in many countries. Therefore, the “worldwide map of vitamin fortification” may be analyzed. It is important to examine if fortification today really answers to vitamin requirements at different ages and/or physiological states. The real impact of vitamin fortification on some key biomarkers is also discussed. An important question also to be addressed: how much is too much? It is becoming more evident that chronic excessive intakes may be harmful and a wide margin of safety seems to be a mandatory practice in dietary recommendations. Finally, the “risk/benefit” dilemma is also considered in the “new” FA-fortified world.

3D-printing models to create custom-made devices for coil embolisation of anastomotic leak after aortic arch replacement

2009 ◽  
Vol 56 (S 01) ◽  
Author(s):  
D Schmauss ◽  
R Sodian ◽  
C Schmitz ◽  
A Bigdeli ◽  
M Schmoeckel ◽  
...  
Keyword(s):  
3D Printing ◽  
Aortic Arch ◽  
Anastomotic Leak ◽  
Coil Embolisation ◽  
Aortic Arch Replacement ◽  
Custom Made

Feasibility of a custom made retrieval modification in minimally invasive transapical aortic valve implantation

2010 ◽  
Vol 58 (S 01) ◽  
Author(s):  
J Blumenstein ◽  
J Kempfert ◽  
S Lehmann ◽  
A van Linden ◽  
D Merk ◽  
...  
Keyword(s):  
Aortic Valve ◽  
Minimally Invasive ◽  
Custom Made ◽  
Aortic Valve Implantation ◽  
Valve Implantation

Regeneration von Knochendefekten mit computergesteuerter Herstellung von Gerüstträgern

2013 ◽  
Vol 22 (03) ◽  
pp. 180-187 ◽  
Author(s):  
J. Henke ◽  
J. T. Schantz ◽  
D. W. Hutmacher
Keyword(s):  
Tissue Engineering ◽  
Additive Manufacturing ◽  
Custom Made

ZusammenfassungDie Behandlung ausgedehnter Knochen-defekte nach Traumata oder durch Tumoren stellt nach wie vor eine signifikante Heraus-forderung im klinischen Alltag dar. Aufgrund der bestehenden Limitationen aktueller Therapiestandards haben Knochen-Tissue-Engineering (TE)-Verfahren zunehmend an Bedeutung gewonnen. Die Entwicklung von Additive-Manufacturing (AM)-Verfahren hat dabei eine grundlegende Innovation ausgelöst: Durch AM lassen sich dreidimensionale Gerüstträger in einem computergestützten Schichtfür-Schicht-Verfahren aus digitalen 3D-Vorlagen erstellen. Wurden mittels AM zunächst nur Modelle zur haptischen Darstellung knöcherner Pathologika und zur Planung von Operationen hergestellt, so ist es mit der Entwicklung nun möglich, detaillierte Scaffoldstrukturen zur Tissue-Engineering-Anwendung im Knochen zu fabrizieren. Die umfassende Kontrolle der internen Scaffoldstruktur und der äußeren Scaffoldmaße erlaubt eine Custom-made-Anwendung mit auf den individuellen Knochendefekt und die entsprechenden (mechanischen etc.) Anforderungen abgestimmten Konstrukten. Ein zukünftiges Feld ist das automatisierte ultrastrukturelle Design von TE-Konstrukten aus Scaffold-Biomaterialien in Kombination mit lebenden Zellen und biologisch aktiven Wachstumsfaktoren zur Nachbildung natürlicher (knöcherner) Organstrukturen.

Design of spline surface vacuum gripper for pick and place robotic arms

2020 ◽  
Vol 4 (2) ◽  
pp. 48-55
Author(s):  
A. S. Jamaludin ◽  
M. N. M. Razali ◽  
N. Jasman ◽  
A. N. A. Ghafar ◽  
M. A. Hadi
Keyword(s):  
Cycle Time ◽  
Industrial Robot ◽  
Annealing Process ◽  
Vacuum Suction ◽  
Robotic Arms ◽  
Custom Made ◽  
Pick And Place ◽  
Manufacturing Procedure ◽  
Production Flexibility ◽  
The Impact

The gripper is the most important part in an industrial robot. It is related with the environment around the robot. Today, the industrial robot grippers have to be tuned and custom made for each application by engineers, by searching to get the desired repeatability and behaviour. Vacuum suction is one of the grippers in Watch Case Press Production (WCPP) and a mechanism to improve the efficiency of the manufacturing procedure. Pick and place are the important process for the annealing process. Thus, by implementing vacuum suction gripper, the process of pick and place can be improved. The purpose of vacuum gripper other than design vacuum suction mechanism is to compare the effectiveness of vacuum suction gripper with the conventional pick and place gripper. Vacuum suction gripper is a mechanism to transport part and which later sequencing, eliminating and reducing the activities required to complete the process. Throughout this study, the process pick and place became more effective, the impact on the production of annealing process is faster. The vacuum suction gripper can pick all part at the production which will lower the loss of the productivity. In conclusion, vacuum suction gripper reduces the cycle time about 20%. Vacuum suction gripper can help lower the cycle time of a machine and allow more frequent process in order to increase the production flexibility.

A Comparison of Two Sub-structuring Techniques for Representing the Modal Properties of Tires

2001 ◽  
Vol 29 (1) ◽  
pp. 23-43 ◽  
Author(s):  
D. Tsihlas ◽  
T. Lacroix ◽  
B. Clayton
Keyword(s):  
Automobile Industry ◽  
Dynamic Models ◽  
Transfer Functions ◽  
Component Mode Synthesis ◽  
Numerical Techniques ◽  
The Past ◽  
Custom Made ◽  
Modal Behavior ◽  
Noise Vibration ◽  
Reduced Dynamic

Abstract Different numerical sub-structuring techniques for the representation of tire modal behavior have been developed in the past 20 years. By using these numerical techniques reduced dynamic models are obtained which can not only be used for internal studies but also be provided to the automobile industry and linked to reduced dynamic vehicle models in order to optimize the coupled vehicle-tire response for noise vibration and harshness purposes. Two techniques that have been developed in a custom-made finite element code are presented: 1) the component mode synthesis type models for which the wheel center interface is free and 2) the Craig and Bampton type models for which the wheel center interface is fixed. For both techniques the interface between the tire and the ground is fixed. The choice of fixed or free wheel center boundary condition is arbitrary. In this paper we will compare the formulation of these two numerical methods, and we will show the equivalency of both methods by showing the results obtained in terms of frequency and transfer functions. We will show that the two methods are equivalent in principle and the reduced dynamic models can be converted from one to the other. The advantages-disadvantages of each method will be discussed along with a comparison with experimentally obtained results.

Management of a Goldenhar Syndrome patient with a custom-made osteosynthesis mesh

2020 ◽  
Vol 4 (3) ◽  
Author(s):  
Carlo Tian ◽  
Ingrid Tonni ◽  
Umberto Zanetti ◽  
Luca Visconti ◽  
Francesco Daleffe ◽  
...  
Keyword(s):  
Goldenhar Syndrome ◽  
Syndrome Patient ◽  
Custom Made
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