WHY ARE TWINS DISSIMILAR?

PEDIATRICS ◽  
1964 ◽  
Vol 33 (3) ◽  
pp. 325-326
Author(s):  
SHIRLEY G. DRISCOLL

TWINNING has captured the imaginations of artist, story-teller, and scientist throughout recorded history. Many studies of the intrapair likenesses and differences of twins have been directed toward elucidation of the interplay between nature and nurture. Yet the dissimilarities which occur within twin pairs may not be recognized and the mechanisms which underlie these differences often are not understood. Indeed, clinical observation of discordance between cotwins seems to evoke surprise, especially when such dissimilarities are evident at birth and in monozygous twins. In terms of the health and survival of the twins, these phenomena may be of critical importance. How do these differences arise? Dissimilarities between dizygous twins are to be expected, reflecting the individual genetic heritage of two siblings, as they evolve contemporaneously.

Think India ◽  
2019 ◽  
Vol 22 (2) ◽  
pp. 463-466
Author(s):  
TUMMALA. SAI MAMATA

A river flows serenely accepting all the miseries and happiness that it comes across its journey. A tree releases oxygen for human beings despite its inner plights. The sun is never tired of its duty and gives sunlight without any interruption. Why are all these elements of nature so tuned to? Education is knowledge. Knowledge comes from learning. Learning happens through experience. Familiarity is the master of life that shapes the individual. Every individual learns from nature. Nature teaches how to sustain, withdraw and advocate the prevailing situations. Some dwell into the deep realities of nature and nurture as ideal human beings. Life is a puzzle. How to solve it is a million dollar question that can never be answered so easily. The perception of life changes from individual to individual making them either physically powerful or feeble. Society is not made of only individuals. Along with individuals it has nature, emotions, spiritual powers and superstitious beliefs which bind them. Among them the most crucial and alarming is the emotions which are interrelated to others. Alone the emotional intelligence is going to guide the life of an individual. For everyone there is an inner self which makes them conscious of their deeds. The guiding force should always force the individual to choose the right path.  Writers are the powerful people who have rightly guided the society through their ingenious pen outs.  The present article is going to focus on how the major elements bound together are dominating the individual’s self through Rabindranath Tagore’s Home and the World (1916)


2014 ◽  
Vol 10 (S305) ◽  
pp. 102-107
Author(s):  
David F. Elmore

AbstractThe Daniel K. Inouye Solar Telescope (DKIST), formerly Advanced Technology Solar Telescope when it begins operation in 2019 will be by a significant margin Earth's largest solar research telescope. Science priorities dictate an initial suite of instruments that includes four spectro-polarimeters. Accurate polarization calibration of the individual instruments and of the telescope optics shared by those instruments is of critical importance. The telescope and instruments have been examined end-to-end for sources of polarization calibration error, allowable contributions from each of the sources quantified, and techniques identified for calibrating each of the contributors. Efficient use of telescope observing time leads to a requirement of sharing polarization calibrations of common path telescope components among the spectro-polarimeters and for those calibrations to be repeated only as often as dictated by degradation of optical coatings and instrument reconfigurations. As a consequence the polarization calibration of the DKIST is a facility function that requires facility wide techniques.


2021 ◽  
Vol 11 ◽  
Author(s):  
Katja Bieber ◽  
Khalaf Kridin ◽  
Shirin Emtenani ◽  
Katharina Boch ◽  
Enno Schmidt ◽  
...  

Pemphigus and pemphigoid diseases are autoimmune bullous diseases characterized and caused by autoantibodies targeting adhesion molecules in the skin and/or mucous membranes. Personalized medicine is a new medical model that separates patients into different groups and aims to tailor medical decisions, practices, and interventions based on the individual patient`s predicted response or risk factors. An important milestone in personalized medicine in pemphigus and pemphigoid was achieved by verifying the autoimmune pathogenesis underlying these diseases, as well as by identifying and cloning several pemphigus/pemphigoid autoantigens. The latter has become the basis of the current, molecular-based diagnosis that allows the differentiation of about a dozen pemphigus and pemphigoid entities. The importance of autoantigen-identification in pemphigus/pemphigoid is further highlighted by the emergence of autoantigen-specific B cell depleting strategies. To achieve this goal, the chimeric antigen receptor (CAR) T cell technology, which is used for the treatment of certain hematological malignancies, was adopted, by generating chimeric autoantigen receptor (CAAR) T cells. In addition to these more basic science-driven milestones in personalized medicine in pemphigus and pemphigoid, careful clinical observation and epidemiology are again contributing to personalized medicine. The identification of clearly distinct clinical phenotypes in pemphigoid like the non-inflammatory and gliptin-associated bullous pemphigoid embodies a prominent instance of the latter. We here review these exciting developments in basic, translational, clinical, and epidemiological research in pemphigus and pemphigoid. Overall, we hereby aim to attract more researchers and clinicians to this highly interesting and dynamic field of research.


2017 ◽  
Vol 41 (S1) ◽  
pp. S588-S588
Author(s):  
M. Mezghani ◽  
F. Fekih-Romdhane ◽  
F. El Ghali ◽  
M. Zghal ◽  
G. Jmii ◽  
...  

IntroductionIncest may be defined as sexual relations between close blood relatives. Legally, incest and sexual aggression toward minors are classified as a criminal behaviour. Tunisia is among the countries from which incest cases are rarely reported.Objectives and methodThe aim of this study is to investigate the relationship between the psychotic structure and incest, and to describe the individual, clinical, and criminal traits of the incestuous father through clinical observation.Case reportMr T.G is 46 years old. He is married and has six daughters. His wife appears to be passive, and largely dependent on her husband. Mr T.G has had incestuous relationships, initially, with his two eldest daughters. The acts were followed by the mother's complicit silence and the non-denunciation of the daughters. Two years later, he starts an incestuous behavior with his third daughter. Incest took place in the context of delusion. The patient was convinced that he is responsible of his daughters’ sexuality education. He develops an incoherent theory of purification with a tendency towards morbid rationalism. It is only after four years of insufferable paternal incestuous relationships that the third daughter filed a complaint to the police. A psychiatric expertise concluded that the accused is exempt from criminal responsibility.ConclusionIncest is a multi-faceted phenomenon, which makes its approach, comprehension, and treatment quite complex. For a psychotic patient incest is a means to deny alterity by crushing other. It also allows him to find, in this complete power, control over his annihilation anxiety.Disclosure of interestThe authors have not supplied their declaration of competing interest.


Author(s):  
Kevin A. Wright

Nearly everyone sent to prison will one day return to the community. This means that understanding recidivism is of critical importance to members of that community. At the most basic level, recidivism can be defined as “the reversion of an individual to criminal behavior after he or she has been convicted of a prior offense, sentenced, and (presumably) corrected.” Recidivism therefore requires that some sort of involvement with the criminal justice system has taken place, and that then the individual again comes into contact with the system after additional transgressions. Recidivism, in other words, is officially detected, repeat unlawful behavior.


2021 ◽  
pp. 329-350
Author(s):  
Jack Bauer

The field of psychology is under a spell of believing that the person is merely a product of nature and nurture. This belief holds that the individual person plays no causal role in their own development. This belief assumes that epiphenomena (like persons, which originate from nature and nurture) lack real agency and cannot be a cause of themselves at a later time, so personal growth and the transformative self are illusions. This chapter explains the faulty logic in such beliefs and presents the nature, nurture, and ‘ndividuality model of personhood, which holds that the individuality of the whole person influences that person’s own development in ways not explained by nature, nurture, or their interaction. This model relies not on notions of free will or even intentionality but rather on another model of the person as a self-organizing system—a dynamic, organismic system within a pluralistic ecology of systems.


2021 ◽  
Vol 12 ◽  
Author(s):  
Cecilia Maria Esposito ◽  
Alessio Fiorentini ◽  
Antonio Callari ◽  
Gian Maria Galeazzi ◽  
Paolo Brambilla

The Sensitive Delusion of Reference is a clinical entity described by Ernst Kretschmer and never integrated into mainstream nosographic systems. It represents the possibility of developing psychosis starting from a personality characterized by sensitivity, scrupulousness, and fear of judgment of others. The presentation of the following clinical case highlights how the overlap between this clinical entity and mood disorders leads to characteristic psychopathology, which has not been sufficiently detailed. In particular, the delusions, which always starts from the idea of reference and the shame in the face of the judgment of others, takes on characteristics of guilt during the depressive phases and persecutory themes during the activation phases. This clinical observation, which obviously needs to be confirmed on a larger scale, encourages a renewed interest in the concept of Kretschmer's Sensitive Delusion of Reference and creates the possibility of intersecting multiple psychopathological levels, for a more complete perspective on the individual case.


The sociological distinction between ascribed and achieved statuses and the typology of roles attached to them construct “status sets” that form the building blocks of class, social inequality and stratification – the most important components of social structure. Among other topics, this chapter addresses the correspondences between work, salvation, piety and economics, by discussing the complexity of meanings in Islam, and through a discourse on Islamic culture. Both theoretically and empirically, we argue that work and social mobility have advanced by placing emphasis on achieved status rather than ascribed status, as in the Protestant vision. The prevalent assumption is that everybody is born with equal capabilities that can be actualized by individual endeavors. Thus, from the Protestant viewpoint, achieved statuses, and the social roles attached to them to build up the social structure, are more individually than socially based. This statement, that reflects a long debate on the role of nature and nurture, does not mean the authors are underestimating societal resources by an emphasis on psychologism. Attempts are made to avoid both sociologism and psychologism especially where theological foundational concerns are built upon here and beyond. Nonetheless, since creation starts with motivation, there are individuals who are prone to uphold and judge their creations to achieve a status without expert information. That is the moment that societal auditioning in various forms hold individuals' estimation of their creation to the societal standards whether in terms of subjectivity of taste or normative demands of a status. By de-emphasizing ascribed status, the individual's endeavors to gain rewards, material or non-material in this world not only contribute to capital accumulation, or prestige, but also open the avenue for the individual who believes in salvation, or engagement in innovation and scientific experimentation. As functionalists suggest, the expectation of reward, failure, and specialization create social inequality – that is, the qualities such as a degree of religiosity that have nothing to do with the stratification of people. If the degree of religiosity, measured by frequency of attending church or mosque, is able to impact drastically upon societal stratification, then the more stratified societies with large gaps between social classes are able to close them harmoniously.


1999 ◽  
Vol 11 (2) ◽  
pp. 48-49 ◽  
Author(s):  
P. Tienari

Nature and nurture are not separate. Instead it is important to investigate the interplay between genes and environment and how they influence on another. To an important degree, genetic effects on behavior come about because they either influence the extent to which the individual is likely to be exposed to individual differences in environmental risk or they affect how susceptible the individual is to environmental adversities.The current inability to explain or predict which genetically predisposed individuals will finally become schizophrenic has forced us to confront our ignorance of the precise mechanism and mode of the transmission of this disorder. Zubin's proposal to view the schizophrenic as a vulnerable individual who develops a temporary episode only under certain provocations can help place the controversy in proper perspective. Vulnerability (predisposition, diathesis) to schizophrenia can be defined as the individual's characteristic treshold beyond which stressful events produce decompensation manifest in the clinically diagnosable symptom picture.


Author(s):  
James Dumesnil

Research has been increasingly clear regarding the critical importance of the first years of life, especially the first three years, on personality development and the ability to adapt and adjust throughout life. Children with histories of traumas such as abuse, neglect, drug exposure, inconsistent caregiving, or violence during these critical early years can have profound disruptions in their development, including severe behavioral and emotional problems. The parents who adopt a child with a history of trauma are vulnerable to developing their own vicarious, or secondary trauma. This chapter explores this contagion of trauma within adoptive families, following the story of one such affected family. Treatment has focused on the needs of the traumatized child individually and through behaviorally-based parenting interventions. The individual clinical needs of the attachment figures, the parents, have not received the attention they deserve. These needs are as critical as addressing the child's trauma in order to allow for creation of a secure attachment with the child.


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