DISCUSSION ON THE USE OF HEXACHLOROPHENE IN THE NURSERY

PEDIATRICS ◽  
1973 ◽  
Vol 51 (2) ◽  
pp. 406-412

Discussion–following papers by Kimbrough, Mullick and Gluck Richard Davis, USC: We have been examining brain sections from infants who have died in our nursery. So far we have found five cases similar to those described by Dr. Lampert. However, they occurred both during the period when hexachlorophene was being used as well as after its use had been discontinued. Dr. Shinefield: What was the concentration of hexachlorophene used? Dr. Davis: One teaspoon of 3% hexachlorophene in a quart of water. Moderator: With such a dilute solution, the amount of hexachborophene actually administered must have been very small. This raises the question as to whether the treated infants form a suitable study group. Dr. Alan Hodson: We have 10 cases showing striking bilateral and symmetrical vacuobation in myelinated areas; six were newborn infants and four were dermatobogical cases. The newborn infants were all immature (27 to 34 weeks' gestation) and received daily baths of 3% hexachiorophene for approximately 8 days. They were selected from 40 infants who died between 1967 and 1971. None of the infants was asphyxiated at birth and none required artificial ventilation. These are preliminary data and we do not yet know what the incidence of these lesions might have been before hexachlorophene bathing was introduced. Dr. Finberg: I would bike to report an observation recently made in Peru which might be a description of chronic hexachborophene toxicity following absorption of the chemical through the intact skin. In a unit established to study nutritional problems in children with severe marasmic kwashiarkor, the children were noted to become lethargic, vomit, and develop neurological manifestations when on special diets.

1978 ◽  
Vol 39 (03) ◽  
pp. 624-630 ◽  
Author(s):  
W E Hathaway ◽  
L L Neumann ◽  
C A Borden ◽  
L J Jacobson

SummarySerial quantitative immunoelectrophoretic (IE) measurements of antithrombin III heparin cofactor (AT III) were made in groups of well and sick newborn infants classified by gestational age. Collection methods (venous vs. capillary) did not influence the results; serum IE measurements were comparable to AT III activity by a clotting method. AT III is gestational age-dependent, increasing from 28.7% of normal adult values at 28-32 weeks to 50.9% at 37-40 weeks, and shows a gradual increase to term infant levels (57.4%) by 3-4 weeks of age. Infants with the respiratory distress syndrome (RDS) show lower levels of AT III in the 33-36 week group, 22% vs. 44% and in the 37-40 week group, 33.6% vs. 50.9%, than prematures without RDS. Infants of 28-32 week gestational age had only slight differences, RDS = 24%, non-RDS = 28.7%. The lowest levels of AT III were seen in patients with RDS complicated by disseminated intravascular coagulation and those with necrotizing enterocolitis. Crossed IE on representative infants displayed a consistent pattern which was identical to adult controls except for appropriate decreases in the amplitude of the peaks. The thrombotic complications seen in the sick preterm infant may be related to the low levels of AT III.


2017 ◽  
Vol 14 (4) ◽  
pp. 3213
Author(s):  
Yasin Demir ◽  
Mustafa Kutlu

In this study, it is studied the effect of group guidance activities which consists of eight sessions and prepared to improve friendship relationships on adolescents’ friendship relationships. The study group consists of 32 adolescents. As a research design, it was used pretest-posttest model with control and placebo groups. The data analysis was made with SPSS 18 packet program, and Anova and Ancova tests were used in the analysis. Friendship relation levels of the participants were measured with Peer Relationships Scale. After the pretest measurement, group guidance activities consisted of eight sessions and intended to improve friendship relationships was applied to experimental group adolescents. Within this period, no procedure was performed with the individuals in the control group, and 3 session presentations about the vocational guidance and examination system were made to the individuals in the placebo group. After the sessions, posttest measurement was given. In the data analysis, two factored variance analysis was used for mixed designs. According to the findings from the study, group guidance program aimed at improving the friendship relationships is effective to improve friendship relationships of adolescents. The findings were discussed taking the literature results into consideration, and the suggestions were made in accordance with the results from this study.Extended English abstract is in the end of PDF (TURKISH) file. ÖzetBu araştırmada, sekiz oturumdan oluşan ve arkadaşlık ilişkilerini geliştirmeye yönelik hazırlanan grup rehberliği etkinliklerinin ergenlerin arkadaşlık ilişkileri üzerindeki etkisi incelenmiştir. Araştırmanın çalışma grubu 32 ergenden oluşmuştur. Araştırma deseni olarak kontrol ve plasebo gruplu ön-test son-test model kullanılmıştır. Verilerin analizinde Anaova ve Ancova testleri kullanılmıştır. Katılımcıların arkadaşlık ilişkileri düzeyleri Akran İlişkileri Ölçeği ile ölçülmüştür. Ön-test ölçümünün ardından deney grubunda yer alan ergenlere sekiz oturumdan oluşan arkadaşlık ilişkilerini geliştirmeye yönelik grup rehberliği etkinlikleri uygulanmıştır. Bu süre içerisinde kontrol grubundaki bireylerle hiçbir işlem yürütülmemiştir. Plasebo grubundaki üyelere ise sadece üç oturumluk mesleki rehberlik ve sınav sistemi ile ilgili sunumlar yapılmıştır. Oturumların sona ermesinden sonra son-test ölçümleri alınmıştır. Elde edilen verilerin analizinde karışık desenler için iki faktörlü varyans analizi tekniği kullanılmıştır. Araştırmadan elde edilen bulgular, arkadaşlık ilişkilerini geliştirmeye yönelik uygulanan grup rehberliği etkinliklerinin ergenlerin arkadaşlık ilişkilerini geliştirmede etkili olduğunu göstermektedir. Bulgular literatür sonuçları dikkate alınarak tartışılmış ve araştırmadan elde edilen sonuçlar doğrultusunda önerilerde bulunulmuştur.


1970 ◽  
Vol 14 (4) ◽  
pp. 375???376
Author(s):  
V. A. PUSEY ◽  
R. I. MACPHERSON ◽  
V. CHERNICK

1979 ◽  
Vol 54 (5) ◽  
pp. 379-383 ◽  
Author(s):  
J Cowen ◽  
S H Ellis ◽  
J McAinsh
Keyword(s):  

2021 ◽  
Vol 10 (85) ◽  

The objective of this study is to explore and interpret Kurt Schwitters’ outside-the-surface Merzbau works in terms of form-meaning relationship. The study was carried on according to hermeneutic model. Documents were used as data collection tool. The study group consists of Merzbau works by Kurt Schwitters. It has been found out by the data obtained that the Merzbau works the artist made in Hannover, Germany and Norway were destroyed, and that his work in England, which he started making in 1947, is his only Merzbau work that survives until today. In the study, analyses were made based on the photographs left from the works and correlations were made with other artists’ works produced at the time. It has been observed that Schwitters composed his works by assembling trashes and found objects to which he assigned his own meaning. It has been seen that this resembles Cabinet of Curiosities in Renaissance. By placing his Merz works on a space, Schwitters transformed them into installations. Therefore, it has been found out that there is a connection between V. Tatlin’s corner counter-reliefs and his transforming the object into an artwork by isolating its worldly task. It has also been observed that the artist influenced Art Povera with the materials he used. It has been stated that throughout his lifetime, some additions could be made on Merzbau works that he created on the basis of concepts such as limitlessness-irregularity-infinity, and therefore, the endpoint of his works can be related to his moment of death. Keywords: Kurt Schwitters, Dada, Installation, Inherent, Avant-garde


PEDIATRICS ◽  
1990 ◽  
Vol 85 (6) ◽  
pp. 1131-1132
Author(s):  
J. PFENNINGER ◽  
H. TSCHAEPPELER

To the Editor.— Because of our longstanding interest in adult respiratory distress syndrome in the pediatric age group, it was a pleasure to read the article about neonatal adult respiratory distress syndrome by Faix et al.1 However, our experience with the neonatal form of the syndrome differs quite substantially from that reported by Faix; and, therefore, we would like to report just briefly our data from the last 20-month period. During this time the diagnosis of adult respiratory distress syndrome according to classcial criteria was made in 5 newborn infants.


PEDIATRICS ◽  
1951 ◽  
Vol 8 (4) ◽  
pp. 518-521
Author(s):  
FRANK E. HYTTEN ◽  
RUTH B. CHERRY

A SATISFACTORY method for obtaining anaerobic arterial blood samples from newborn infants requires at least the following conditions: 1. It must be safe. 2. The sampling must be sufficiently rapid to give blood values for any given half a minute or less. 3. Pain must be minimal so that crying can be avoided. 4. Repeated sampling on one infant should be possible. Arterial puncture is both safe and rapid in only a few experienced hands and repeated sampling is even less safe or sure. Crying is seldom avoided. Cutaneous bleeding from heel puncture frequently produces mixed blood and bleeding is almost always too slow to give an accurate picture of the state of the blood at a given moment. Crying is the rule. In addition, the usual method of collection under oil introduces further inaccuracies: oil slows the bleeding, absorbs a considerable amount of carbon dioxide, and is extremely difficult to exclude from pipettes. The present investigators have evolved a method which has proved satisfactory in about 50 consecutive cases. "Cutaneous" arterial blood is sampled from the foot, the site of puncture being over the soft tissue area containing the plexus of arterioles from the lateral malleolar artery (Fig. 1). Equipment Three pieces of equipment, easily made in any laboratory, are required: 1. As shown in Fig. 2, this consists of a 1" X 1" square of adhesive tape which has a centrally punched hole of ⅛" diameter, centered over which and sealed by rubber cement is a ¼" length of soft rubber tubing of ⅛" bore and 3/32" wall thickness.


PEDIATRICS ◽  
1960 ◽  
Vol 25 (5) ◽  
pp. 907-918
Author(s):  
A. F. Hardyment ◽  
R. A. Wilson ◽  
W. Cockcroft ◽  
Betty Johnson

THE STUDY of the control of skin infections of the newborn infants was started in the winter of 1948-49, when the incidence of pyoderma neonatorum in the nurseries of the Vancouver General Hospital reached a rate of 121 cases per 1000 live-births. At that time the nursery techniques were improved and there was a change from "dry" skin care to the application of 1% ammoniated mercury ointment. This did not prove to have a lasting beneficial effect. From January 1, 1948 until April 30, 1952, the incidence of pyoderma varied in a most unpredicted manner. From May 1, 1952 until December 31, 1956, various methods of skin care were used experimentally to determine the effect of these on the pyoderma rate in the nurseries. During these observations, a study was made of various other aspects of the epidemiology of pyoderma neonatorum: 1. Studies of staphylococcal contamination of the environment. a) Nasal carrier rate of infants, mothers, nurses and other personnel. b) Nursery air. c) The intact skin of normal infants versus infants with pyoderma. d) Mothers' hands and bedding. e) Nurses' hands and gowns. f) Babies' tubs and bedding. 2. Identification by phage-typing and antibiotic resistance of the organisms isolated. a) From pustules. b) From nasal carriers. 3. Observation of the cytology of exudate from pustules (bacterial and nonbacterial). THE NURSERIES In the Women's Pavilion of the Vancouver General Hospital are six regular nurseries providing from 21.0 to 31.0 square feet per bassinet. The number of bassinets per nursery ranges from 12 to 22. The daily census shows that the per cent of occupancy ranges from 61 to 81.


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