Growth of Escherichia coli and Concentration of Iron in an Infant Feeding Formula

PEDIATRICS ◽  
1978 ◽  
Vol 62 (6) ◽  
pp. 1072-1074
Author(s):  
Robert S. Baltimore ◽  
John S. Vecchitto ◽  
Howard A. Pearson
Keyword(s):  
Escherichia Coli ◽  
Iron Deficiency ◽  
Low Socioeconomic Status ◽  
Iron Supplementation ◽  
Cow’S Milk ◽  
Iron Fortification ◽  
Low Socioeconomic ◽  
Cow's Milk ◽  
Serious Infection ◽  
Increased Risk

Iron deficiency reaches epidemic proportions in infants, particularly those of low socioeconomic status.1 In an attempt to decrease the frequency of this deficiency, iron fortification of infant cereals and cow's milk formulas has been advocated.2 Although the prevention of iron deficiency is a valid nutritional goal, concern has recently been voiced about possible detrimental effects of iron supplementation.3,1 This concern has been based on studies indicating an association between hyperferremia and serious infection,3,6 and also by denionstrations that the bacteriostatic properties of serum and milk can be abolished by the addition of iron.7,8 These findings have been extrapolated into suggestions that the iron supplementation of cow's milk formulas might predispose the infants consuming them to an increased risk of bacterial infection and even that ironcontaining formulas might be contraindicated.4

scholarly journals The Consequence of Excessive Consumption of Cow’s Milk: Protein-Losing Enteropathy with Anasarca in the Course of Iron Deficiency Anemia—Case Reports and a Literature Review

Nutrients ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 828
Author(s):  
Karolina Graczykowska ◽  
Joanna Kaczmarek ◽  
Dominika Wilczyńska ◽  
Ewa Łoś-Rycharska ◽  
Aneta Krogulska
Keyword(s):  
Iron Deficiency ◽  
Literature Review ◽  
Iron Deficiency Anemia ◽  
Case Reports ◽  
Deficiency Anemia ◽  
Cow’S Milk ◽  
Milk Consumption ◽  
Protein Losing Enteropathy ◽  
Cow's Milk ◽  
Excessive Consumption

Cow’s milk is a key component of a child’s diet. While the consumption of even trace amounts can result in allergy to its proteins and/or hypolactasia, excessive cow’s milk consumption can result in numerous health complications, including iron deficiency, due to the diet being improperly balanced. Although the incidence of iron deficiency has declined, it remains the most widespread nutritional deficiency globally and the most common cause of anemia. One rare consequence of anemia caused by iron deficiency is protein-losing enteropathy; however, the mechanisms of its development are unclear. The following manuscript, based on a literature review, presents two rare cases of children, a 16-month-old boy and a 2.5-year-old girl, who developed severe microcytic anemia, enteropathy with hypoalbuminemia, and anasarca as a result of excessive cow’s milk consumption. It highlights the possible relationship between excessive consumption of cow’s milk in children and severe iron deficiency anemia with accompanying hypoalbuminemia; it may also result in serious clinical conditions, even in children that do not demonstrate food hypersensitivity.

scholarly journals A study on cow's milk and nursing method in relation to iron deficiency

2006 ◽  
Vol 49 (2) ◽  
pp. 144 ◽  
Author(s):  
Ji Ung Kang ◽  
So Hee Jin ◽  
Kyung Dan Choi ◽  
Young Taek Jang
Keyword(s):  
Iron Deficiency ◽  
Cow’S Milk ◽  
Cow's Milk

scholarly journals Association between Carbohydrate Intake and the Prevalence of Metabolic Syndrome in Korean Women

Nutrients ◽  
2021 ◽  
Vol 13 (9) ◽  
pp. 3098
Author(s):  
Young-Ae Cho ◽  
Jeong-Hwa Choi
Keyword(s):  
Metabolic Syndrome ◽  
Low Socioeconomic Status ◽  
Carbohydrate Intake ◽  
Korean Women ◽  
Cross Sectional ◽  
Low Socioeconomic ◽  
Reactive Protein ◽  
Dairy Intake ◽  
Increased Risk ◽  
Sectional Analysis

Carbohydrates consist of a large proportion of calories in the Asian diet. Therefore, we aimed to investigate the association between carbohydrate intake and metabolic syndrome in Korean women. A cross-sectional analysis was conducted with a total of 4294 Korean women aged 40–69 years from the Korean Genomic and Epidemiology Study (KoGES). Carbohydrate intake was calculated based on a validated food frequency questionnaire. Metabolic syndrome was defined by using the National Cholesterol Education Program, Adult Treatment Panel III (NCEPIII). Logistic regression was used to estimate the association of carbohydrate intake with metabolic syndrome and its components. In this study, high carbohydrate intake seemed to be associated with low socioeconomic status and an imbalanced diet. After adjusting for confounding factors, subjects with higher carbohydrate intake showed an increased risk of metabolic syndrome (odds ratio (OR) 1.34, 95% confidence interval (CI) 1.08–1.66, p-trend = 0.004, highest vs. lowest quartile [≥75.2 vs. <67.0% of energy]), particularly elevated waist circumference. This association was stronger among those with low levels of C-reactive protein (CRP) and those with low dairy intake. In conclusion, higher carbohydrate intake is associated with a higher risk of metabolic syndrome, particularly abdominal obesity, in Korean women. This association may differ according to individuals’ CRP level and dairy intake.

Whole Cow's Milk, Age, and Gastrointestinal Bleeding

PEDIATRICS ◽  
1984 ◽  
Vol 73 (6) ◽  
pp. 879-880
Author(s):  
JOHN F. WILSON
Keyword(s):  
Blood Loss ◽  
Gastrointestinal Bleeding ◽  
American Academy ◽  
Iron Supplementation ◽  
Occult Blood ◽  
Cow’S Milk ◽  
Cow's Milk ◽  
American Academy Of Pediatrics ◽  
Recent Statement

To the Editor.— The recent statement by the American Academy of Pediatrics' Committee on Nutrition1 raises "unanswered" questions. There may be an answer to question 3: "Can the change to cow's milk when the unfant is 6 months old produce anemia from occult blood loss when the milk is fed in excessive amounts and there is no iron supplementation?" [See table in the PDF file] The answer is to be found in a review of the research records of the 34 subjects in a 1974 report2; the records contain detailed dietary histories recorded by me.

Too Much of a Good Thing? Cerebral Sinovenous Thrombosis Due to Excessive Milk Intake Associated Anemia

2020 ◽  
Vol 35 (9) ◽  
pp. 585-590
Author(s):  
Raquel Farias-Moeller ◽  
Sara Siddiqui ◽  
Megan Orr ◽  
Lileth Mondok
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Mean Corpuscular Volume ◽  
Milk Intake ◽  
Deficiency Anemia ◽  
Cow’S Milk ◽  
Corpuscular Volume ◽  
Cow's Milk ◽  
Cerebral Sinovenous Thrombosis ◽  
Sinovenous Thrombosis

Introduction: In young children, excessive cow’s milk intake causes iron-deficiency anemia, which is associated with hypercoagulable states. We present a case series of 4 toddlers with excessive milk intake iron-deficiency anemia and cerebral sinovenous thrombosis. Methods: Retrospective chart review of 4 patients was performed for patients with cerebral sinovenous thrombosis and iron-deficiency anemia secondary to excessive milk intake. Iron-deficiency anemia was defined as hemoglobin <11 mg/dL, mean corpuscular volume <70 fL, and serum ferritin <12 μg/L. Excessive milk intake was defined as consumption of >24 oz daily. Clinical, laboratory, and radiographic features were reviewed. Results: Age ranged from 12 to 24 months. Average hemoglobin, hematocrit, mean corpuscular volume, and ferritin levels were 6.1 g/dL, 22.7 g/dL, 52.7 fL, and 3.2 ng/mL, respectively. Daily milk consumption ranged from 40 to 60 oz. All patients presented with focal neurologic deficits, including seizures in 3. The location of cerebral sinovenous thrombosis varied, and 3 patients had venous infarcts, one of them hemorrhagic. All patients had a limited diet and were described as “picky eaters” by their parents, and only 1 had transitioned of a bottle. All patients were treated with anticoagulation, iron supplementation, and extensive dietary counseling to reduce cow’s milk intake. Conclusion: Iron-deficiency anemia due to excessive milk intake is an important and preventable etiology of pediatric cerebral sinovenous thrombosis. Focused anticipatory guidance is necessary for at-risk groups to prevent this neurologic emergency.

scholarly journals Relation of Sociodemographics and Personal Hygiene on Different Childhood Dermatoses

2015 ◽  
Vol 13 (1) ◽  
pp. 29-33
Author(s):  
E Gauchan ◽  
A Kumar ◽  
G BK ◽  
P Thapa ◽  
J Pun
Keyword(s):  
Socioeconomic Status ◽  
Low Socioeconomic Status ◽  
Skin Disease ◽  
Skin Diseases ◽  
Public Health Problem ◽  
Personal Hygiene ◽  
Cross Sectional ◽  
Dermatology Department ◽  
Low Socioeconomic ◽  
Increased Risk

Background Skin diseases in children contribute to significant morbidity and psychological distress. Infective dermatoses are one of the major dermatoses in children. Low socioeconomic status, overcrowding and poor personal hygiene has been linked to skin diseases.Objective To find out the prevalence of infectious skin disease in children, rate of transmissible skin disease and association of sociodemographic factors and personal hygiene on infective childhood dermatoses.Method This was a cross-sectional study conducted in the Pediatric and Dermatology Department, Manipal Teaching Hospital, Pokhara, Nepal. A total of 226 patients were examined over a period of one year. Relation of sociodemographics, crowding and personal hygiene on skin disease were assessed.Result The most common category was Infections and Infestations (51.3%) followed by Dermatitis (27.9%) . Transmissible skin disease was seen in 49.6%. Low socioeconomic status and overcrowding were associated with increased risk for infective dermatoses.Conclusion Skin disease in children constitutes a public health problem. Improving the socioeconomic status and personal hygiene can help to reduce the incidence of skin disease in children.Kathmandu University Medical Journal Vol.13(1) 2015; 29-33

Prolonged elevations in haemostatic and rheological responses following psychological stress in low socioeconomic status men and women

2003 ◽  
Vol 89 (01) ◽  
pp. 83-90 ◽  
Author(s):  
Sabine Kunz-Ebrecht ◽  
Ann Rumley ◽  
Gordon Lowe ◽  
Andrew Steptoe
Keyword(s):  
Socioeconomic Status ◽  
Factor Viii ◽  
Psychological Stress ◽  
Low Socioeconomic Status ◽  
Stress Responses ◽  
Blood Viscosity ◽  
Stress Reactivity ◽  
Plasma Viscosity ◽  
Low Socioeconomic ◽  
Increased Risk

SummaryLow socioeconomic status (SES) and psychological stress are associated with increased risk of coronary heart disease, and both may influence haemostatic responses. Von Willebrand factor (vWF), Factor VIII, plasma viscosity, haematocrit, blood viscosity, tissue plasminogen activator (t-PA) and fibrin D-dimer were measured at rest and following stressful tasks in 238 middle-aged British civil servants. SES was defined by grade of employment. Lower SES was associated with higher resting vWF, Factor VIII and plasma viscosity. Psychological stress stimulated increases in haemostatic and rheological factors. Initial stress responses did not vary with SES, but Factor VIII, plasma viscosity and blood viscosity remained more elevated 45 minutes post-stress in lower SES participants. High blood pressure stress reactivity was also associated with greater haemostatic responses. We conclude that lower SES is characterised by more prolonged elevations in procoagulant responses following psychological stress, and that these processes might contribute to increased cardiac risk.

Severe Iron-Deficiency Anemia Still an Issue in Toddlers

2014 ◽  
Vol 53 (14) ◽  
pp. 1352-1358 ◽  
Author(s):  
Gabrielle Paoletti ◽  
Debra L. Bogen ◽  
A. Kim Ritchey
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Motor Development ◽  
Retrospective Chart Review ◽  
Microcytic Anemia ◽  
Deficiency Anemia ◽  
Cow’S Milk ◽  
Milk Consumption ◽  
Cow's Milk ◽  
The Mean

Background and Objectives. Chronic, severe iron-deficiency anemia (IDA) in the first years of life increases the risk of irreversibly compromised cognitive, affective, and motor development. While IDA in infants has decreased because of dietary changes (iron-fortified formula and delaying cow’s milk), toddlers (13-36 months) are equally vulnerable to the adverse effects of IDA. We aimed to show that despite public health efforts, severe IDA remains a problem in toddlers and is associated with excess milk consumption. Methods. Retrospective chart review of children 6 to 36 months admitted to or evaluated by hematology at a children’s hospital from January 1, 2005 to December 31, 2010 with a severe microcytic anemia (hemoglobin [Hb] <9 g/dL and mean corpuscular volume (MCV) <75 fL). Results. We identified 68 infants and toddlers with severe IDA; most (84%) were 13 to 36 months old. The mean Hb and MCV were 6.0 g/dL (range = 2.2-8.9 g/dL) and 54.0 fL (range = 45.5-69.8 fL), respectively. Fatigue, poor appetite, and pica were the most common symptoms, found in 43%, 29%, and 22% of patients, respectively. Only 41% of parents reported pale skin while 77% of physicians recorded it on physical exam. Daily cow’s milk consumption surpassed 24 ounces for 47 of 48 children with reported intake; 11 consumed more than 64 ounces per day. Conclusions. Despite current screening recommendations, severe IDA continues to be a problem in toddlers and strongly correlates with excess cow’s milk consumption. This reiterates the importance of screening for IDA into routine toddler care.

Iron deficiency

2018 ◽  
Author(s):  
John Puntis
Keyword(s):  
Iron Deficiency ◽  
Low Socioeconomic Status ◽  
Low Birthweight ◽  
Educational Achievement ◽  
Poor Response ◽  
Underlying Disease ◽  
Cow Milk ◽  
First Year ◽  
Low Socioeconomic ◽  
First Year Of Life

Iron deficiency is the most common nutritional deficiency in the world, affecting around 5 billion people mostly in developing countries. Risk factors in infants include low birthweight, high cow milk consumption, low intake of iron containing complementary foods, low socioeconomic status, and immigrant status. Developmental delay and poor educational achievement are among the long-term complications. Preventative strategies include promotion of breastfeeding, use of iron-fortified formula if breast milk not available, encouraging intake of iron-rich foods, vitamin C-rich drinks with meals to promote iron absorption, and avoiding whole cow’s milk in the first year of life. Poor response to oral iron treatment is most likely due to poor compliance (iron ingestion may cause abdominal pain diarrhoea or constipation) but should also raise the possibility of underlying disease causing inflammation, malabsorption, or blood loss.

Sign in / Sign up

Export Citation Format

Share Document