Excellent Outcome of Bacteroides Meningitis in a Newborn Treated with Metronidazole

PEDIATRICS ◽  
1980 ◽  
Vol 66 (3) ◽  
pp. 463-465
Author(s):  
Barbara J. Law ◽  
Melvin I. Marks
Keyword(s):  
Case Report ◽  
Clinical Cure ◽  
White Male ◽  
Bacteroides Fragilis ◽  
Male Infant ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Excellent Outcome

Hydrocephalus has developed in all three reported cases of Bacteroides fragilis meningitis in newborns.1-3 One author suggested this complication was related to the documented persistence of Bacteroides in the CSF despite chloramphenicol therapy.3 In two of the cases metronidazole was tried late in the course, followed by prompt clinical and bacteriologic resolution.1,3 We report a newborn with B fragilis meningitis in whom metronidazole was used early, with rapid sterilization of the CSF, clinical cure, and no sequelae after 12 months of follow-up. CASE REPORT A 2,020-gm white male infant was delivered vaginally at 32 weeks gestation to a healthy primigravida, 52 hours after premature rupture of membranes.

scholarly journals Treatment of mid-trimester preterm premature rupture of membranes (PPROM) with multi-resistant bacteria-colonized anhydramnion with continuous amnioinfusion and meropenem: a case report and literature review

2021 ◽  
Author(s):  
Michael Tchirikov ◽  
Ronja Ocker ◽  
Gregor Seliger ◽  
Katarina Chaoui ◽  
Stefan Moritz ◽  
...  
Keyword(s):  
Male Infant ◽  
Resistant Bacteria ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Amniotic Cavity ◽  
E Coli ◽  
Preterm Premature Rupture ◽  
Systemic Antibiotics

Abstract Purpose Treatment of mid-trimester classic preterm premature rupture of membranes (PPROM) with systemic antibiotics has limited success in the prevention of chorioamnionitis, funisitis and fetal inflammatory response syndrome because of very low transplacental passage. Methods Here we report a case of PPROM at 18 weeks gestation with anhydramnion colonized by multi-resistant Escherichia coli (E. coli). A catheter system was implanted at 23/2nd weeks gestation, enabling long-term continuous lavage of the amniotic cavity with Amnion Flush Solution (100 ml/h combined with intraamniotic meropenem application). Results The patient gave birth to a preterm male infant at 28/3rd without any signs of infection. In a follow-up examination at 24 months, there was no neurological disturbance or developmental delay. Conclusion The classic PPROM with multi-resistant E. coli colonization could be treated with continuous amnioinfusion and meropenem.

scholarly journals Changes in Umbilical and Cerebral Blood Flow in Pregnancies Diagnosed with Clinical Chorioamnionitis. Is Chorioamnionitis Predictable?

2019 ◽  
pp. 1
Author(s):  
Berfin Okmen Ozkan ◽  
Emre Ekmekci
Keyword(s):  
Umbilical Artery ◽  
Demographic Data ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Preterm Premature Rupture ◽  
Significant Difference ◽  
Umbilical Artery Doppler ◽  
Doppler Evaluation ◽  
Umbilical Arteries

<p><strong>Objective:</strong> To evaluate the predictability of clinical chorioamnionitis by Doppler changes in fetal middle cerebral and umbilical arteries, at hospitalized patients due to preterm premature rupture of membranes.</p><p><strong>Study Design:</strong> Patients who were admitted and hospitalized due to preterm premature rupture of membranes between 24 weeks and 33 weeks and 6 days pregnancies are included in the study. Demographic data of patients, gestational age at referring to hospitalization, fetal presentation at admission, delivery time, delivery indications and total follow-up time until delivery of each case were recorded.</p><p><strong>Results:</strong> A total of 108 patients were evaluated retrospectively. The rate of clinical chorioamnionitis was 5.55% (6/108). There was no significant difference between pregnancies terminated with the diagnosis of clinical chorioamnionitis and pregnancies terminated with other indications in terms of the maximum systolic velocity at middle cerebral artery and umbilical artery pulsatility indices.</p><p><strong>Conclusion:</strong> Clinical chorioamnionitis is a serious complication and is more common in patients being followed up after preterm premature rupture of membranes. Although it is crucial to be predicted due to neonatal worse prognosis, it cannot be predicted by middle cerebral and umbilical artery Doppler evaluation.</p>

A case of severe SARS-CoV-2 infection with negative nasopharyngeal PCR in pregnancy

2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Anna Fuchs ◽  
Lauren Harris ◽  
Ashley Huber ◽  
Mia Heiligenstein ◽  
Cassandra Heiselman ◽  
...  
Keyword(s):  
Clinical Presentation ◽  
Clinical Status ◽  
Igg Antibodies ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Case Presentation ◽  
Preterm Premature Rupture ◽  
High Clinical Suspicion ◽  
Maternal Status

Abstract Objectives SARS-CoV-2 remains a pressing issue for our obstetric community during the current pandemic. We present a case of a 22-year-old nulliparous woman 31 weeks pregnant, with significant clinical SARS-CoV-2 disease, in the setting of negative nasopharyngeal PCR testing but positive IgG antibodies. Case presentation This was a 22-year-old patient 31 weeks pregnant who presented with fever, tachycardia, and subsequently preterm premature rupture of membranes (PPROM) and pulmonary emboli with multifocal pneumonia. The patient underwent three negative SARS-CoV-2 tests via nasopharyngeal PCR testing during her hospital stay as well as a negative workup for fever. After a cesarean section for worsening maternal status after 7 days of hospitalization, the patient was admitted for worsening clinical status to the SICU. At the time of SICU admission patient was found to have serum IgG positive antibodies and was managed with intubation, antibiotics, and anticoagulation. Patient eventually left hospital against medical advice on hospital day 16 on oral antibiotics but was found to be recovering well at later outpatient follow up. Conclusions Diagnosis of SARS-CoV-2 remains a complicated picture in the setting of testing limitations. This case highlights an antepartum clinical presentation of severe SARS-CoV-2 and recommends a high clinical suspicion for diagnosis of SARS-CoV-2 and initiation of treatment in the pregnant population, even in the presence of negative nasopharyngeal PCR testing.

scholarly journals Effect of premature rupture of membranes on the maternal and fetal prognosis during childbirth at the gynecology-obstetrics department of the Matam Communal Medical Center, Conakry, Guinea

2020 ◽  
Vol 9 (3) ◽  
pp. 911
Author(s):  
Ibrahima Conté ◽  
Diallo Boubacar Alpha ◽  
Bah Oumou Hawa ◽  
Touré Souleymane ◽  
Baldé Ibrahima Sory ◽  
...  
Keyword(s):  
Respiratory Distress ◽  
Vaginal Discharge ◽  
Medical Center ◽  
Mode Of Delivery ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Main Mode ◽  
Uterine Contractions ◽  
Genital Hygiene

Background: Premature rupture of membranes (RPM) is defined by rupture of the amnion and chorion before entering labor within 24 hours leading to vaginal discharge of amniotic fluid without uterine contractions. Objective of this study was to improving the management of premature Ruptures of the membranes received in the service.Methods: This was a descriptive and analytical prospective study lasting six months from January 1 to June 30 2016.Results: During the study period, we collected 108 cases of RPM out of 1543 deliveries, representing a hospital frequency of 7%. RPM had more frequently concerned pregnant women aged 25-29 (37.04%), housewife (37.03%), primiparous (45.37%) and referral (52.78%). 95.37% were single pregnancies with cephalic presentation (80%) received between 37-42 weeks (84.26%). Management mainly consisted of antibiotic prophylaxis (100%), fetal pulmonary maturation and childbirth. The vagina was the main mode of delivery (62.04%). The maternal prognosis was dominated by chorioamnionitis (12.96%). The fetal one was made up of respiratory distress (40.71%) and prematurity (12.39%).Conclusions: RPM is frequent at the Matam municipal medical center. It is essential for its prevention to ensure health education of the population in general and genital hygiene in particular, to make a coherent prenatal follow-up while putting a particular accent on the detection and the treatment of genital infections.

scholarly journals Obstetric Management of Copperhead Snake Envenomation in Pregnancy: A Case Report

2019 ◽  
Vol 2 (2) ◽  
pp. 35-41
Author(s):  
Michelle J. Wang ◽  
Michelle Y. Lu ◽  
Elizabeth B. Ausbeck ◽  
Lorie M. Harper
Keyword(s):  
Case Report ◽  
Preterm Labor ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Fetal Outcomes ◽  
Snake Envenomation ◽  
Preterm Premature Rupture ◽  
Antenatal Steroids ◽  
Obstetric Management ◽  
In Pregnancy

Snakebites in pregnancy can result in significant maternal and fetal harm; however, the literature to guide management of this rare obstetric complication remains limited. We describe our approach to envenomation in pregnancy based on the currently available evidence. A 27-year-old G2P1 female presented at 27 weeks’ gestation after suffering a copperhead snakebite. She received antivenom and antenatal steroids without adverse maternal or fetal event. Antenatal testing was reassuring throughout admission, and she was discharged home with plans for close outpatient surveillance. She later developed preterm premature rupture of membranes and preterm labor, with delivery of a live infant at 33 weeks’ gestation. The risk of adverse maternal and fetal outcomes following snake envenomation in pregnancy may warrant closer antenatal surveillance than has been previously described.

scholarly journals Ketuban pecah dini dan tatalaksananya

2019 ◽  
Vol 19 (3) ◽  
Author(s):  
Mohd. Andalas ◽  
Cut Rika Maharani ◽  
Evans Rizqan Hendrawan ◽  
Muhammad Reva Florean ◽  
Zulfahmi Zulfahmi
Keyword(s):  
Case Report ◽  
Early Diagnosis ◽  
Preterm Delivery ◽  
Morbidity And Mortality ◽  
Perinatal Morbidity ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Diagnosis And Management

Abstrak. Ketuban Pecah Dini (KPD) atau Premature rupture of Membranes (PROM) merupakan pecahnya ketuban yang terjadi sebelum proses persalinan. Ketuban pecah dini terjadi sekitar 1% dari seluruh kehamilan. Ketuban pecah dini menyebabkan terjadinya 1/3 persalinan preterm dan merupakan penyebab 18%-20% dari morbiditas dan mortalitas perinatal. Dalam laporan kasus ini kami melaporkan seorang ibu hamil berusia 35 tahun, gravida 3, hamil aterm dengan ketuban pecah dini, keluhan keluar air dari jalan lahir dan belum inpartu. Laporan kasus ini bertujuan untuk meningkatkan kualitas diagnosa dini serta penatalaksanaan ketuban pecah dini untuk mengurangi risiko bagi ibu dan janin. Abstract.Premature Rupture of Membranes (PROM) is the rupture of amniotic sac prior to the onset of labor beyond 37 week of gestation. Premature Rupture of Membranes occurs in 1% ofall pregnancies. Premature Rupture of Membranes causes 1/3 preterm delivery and a major  18%-20% cause of perinatal morbidity and mortality. In this case report we reported a 35 year old woman with pregnant 3rd child, aterm wiht Premateur rupture of Membrane (PROM) and prior to labor. This report aims to improve the quality of early diagnosis and management of premature rupture of membranes to reduce the risk for the mother and fetus. 

scholarly journals Prolonged SARS-CoV-2 Viral Shedding in Pregnancy and Risk of Extended inPatient Isolation: A Case Report

2020 ◽  
pp. 1-5
Author(s):  
Emad A Elsamadicy ◽  
Emad A Elsamadicy ◽  
Mary E Burgoyne ◽  
Naomi Hauser ◽  
Andrea Desai
Keyword(s):  
Case Report ◽  
Severe Acute Respiratory Syndrome ◽  
Healthcare Systems ◽  
Clinical Aspects ◽  
Negative Consequences ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Viral Shedding ◽  
Preterm Premature Rupture ◽  
In Pregnancy

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus responsible for coronavirus disease 2019 (COVID-19), continues to challenge healthcare systems worldwide, and further investigation is required to determine its effects on the pregnant population. Prolonged viral shedding (>15-33 days), especially without appropriate testing guidelines, can subject admitted patients to unnecessarily long isolation, which influences emotional, physical, and clinical aspects of their antepartum course. We report a young, primigravida Haitian female admitted to the antepartum service at 22 weeks of gestation with preterm premature rupture of membranes (PPROM), who remained admitted in isolation for over 6 weeks due to persistent positive SARS-CoV-2 testing. This case highlights the importance of establishing testing guidelines to prevent unnecessary isolation, which has negative consequences for patient care. There is an urgent need for updated guidelines for the duration of isolation based on the presence of the viable virus.

scholarly journals An unusual traumatic delivery malpractice: a case report

2018 ◽  
Vol 87 (1) ◽  
pp. 36-38
Author(s):  
Azadeh Memarian ◽  
Seyed Hossein Moosavinezhad Baboli ◽  
Nahid Dadashzadeh Asl
Keyword(s):  
Case Report ◽  
Caesarean Section ◽  
Gestational Age ◽  
Labour Pain ◽  
The Body ◽  
Medical Professionals ◽  
Mechanical Forces ◽  
Vaginal Examination ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture

Head trauma may occur during delivery and can lead to a number of conditions. When an infant is injured during birth, the cause of injury is generally due to mechanical forces, such as compression, excessive or abnormal traction during delivery, and the use of forceps. A 39-year-old woman who was a primagravida (first pregnancy) with a gestational age of 26 weeks premature pregnancy was referred to a hospital in Tehran due to premature rupture of membranes (PROM) and fever. She arrived 2 h after rupture (noting that the rupture lasted for one week and then the baby was delivered). Antibiotics were given early on. After weak labour pain, vaginal examination revealed that the cervix was fully dilated and one of the feet of the foetus had come out of the cervix and was seen in the vagina. The foetus had died. The delivery staff used traction with force. Due to the age of the foetus, the head was relatively big and could not be delivered; the neck was thin and broken and the head separated from the body. The mother underwent a caesarean section to deliver the head of the foetus a week after PROM. The father of the dead newborn foetus sued the hospital and the staff responsible for the delivery. When medical professionals damage the trust between patients and their families and babies are injured children, they should be held accountable.

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