Bridging the Knowledge Gaps in Arrhythmogenic Cardiovascular Conditions: The Critical Role of Registries

2016 ◽  
Vol 10 (2) ◽  
pp. 1 ◽  
Author(s):  
Melody Hermel ◽  
Rebecca Duffy ◽  
Alexander Orfanos ◽  
Isabelle Hack ◽  
Shayna McEnteggart ◽  
...  

Cardiac registries have filled many gaps in knowledge related to arrhythmogenic cardiovascular conditions. Despite the less robust level of evidence available in registries when compared with clinical trials, registries have contributed a range of clinically useful information. In this review, the authors discuss the role that registries have played – related to diagnosis, natural history, risk stratification, treatment, and genetics of arrhythmogenic cardiovascular conditions – in closing knowledge gaps, and their role in the future.

Nutrients ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 1442
Author(s):  
Pau Vancells Lujan ◽  
Esther Viñas Esmel ◽  
Emilio Sacanella Meseguer

NAFLD is the world’s most common chronic liver disease, and its increasing prevalence parallels the global rise in diabetes and obesity. It is characterised by fat accumulation in the liver evolving to non-alcoholic steatohepatitis (NASH), an inflammatory subtype that can lead to liver fibrosis and cirrhosis. Currently, there is no effective pharmacotherapeutic treatment for NAFLD. Treatment is therefore based on lifestyle modifications including changes to diet and exercise, although it is unclear what the most effective form of intervention is. The aim of this review, then, is to discuss the role of specific nutrients and the effects of different dietary interventions on NAFLD. It is well established that an unhealthy diet rich in calories, sugars, and saturated fats and low in polyunsaturated fatty acids, fibre, and micronutrients plays a critical role in the development and progression of this disease. However, few clinical trials have evaluated the effects of nutrition interventions on NAFLD. We, therefore, summarise what is currently known about the effects of macronutrients, foods, and dietary patterns on NAFLD prevention and treatment. Most current guidelines recommend low-calorie, plant-based diets, such as the Mediterranean diet, as the most effective dietary pattern to treat NAFLD. More clinical trials are required, however, to identify the best evidence-based dietary treatment approach.


2021 ◽  
Vol 27 (8) ◽  
pp. 773-775
Author(s):  
Mei Qin ◽  
Cunshan Peng ◽  
Qingke Wang

ABSTRACT Introduction: Physical exercise can enhance the body's ability to adapt to the external environment and improve the contractility of the heart. At the same time, it can help improve blood circulation and increase lung capacity. Objective: This article explores the critical role of sports in the prevention of cardiovascular diseases. Methods: This article conducts tests on related physiological indicators such as hemodynamic rheology for students who regularly participate in physical exercise and those who do not participate in physical exercise. Results: Students who exercise regularly and those who do not exercise mobilize faster cardiovascular function at the beginning of work. This shows good adaptability to sports. Conclusion: The use of fitness exercise prescription by students who exercise comprehensively has the most pronounced effect on improving vascular function. Level of evidence II; Therapeutic studies - investigation of treatment results.


Circulation ◽  
1989 ◽  
Vol 80 (5) ◽  
pp. 1148-1158 ◽  
Author(s):  
K B Schechtman ◽  
R J Capone ◽  
R E Kleiger ◽  
R S Gibson ◽  
D J Schwartz ◽  
...  

2017 ◽  
Vol 89 (2) ◽  
pp. 183-188
Author(s):  
Robert E. Belford ◽  
Jonathan E. Forman

AbstractIn May and June of 2016 the Organisation for the Prohibition of Chemical Weapons (OPCW), IUPAC and the ACS CHED Committee on Computers in Chemical Education (CCCE) collaboratively ran an online conference hosted with the online ConfChem conference system on “Science, Disarmament and Diplomacy in Chemical Education.”This ConfChem Online Conference was designed to highlight the work of the OPCW and the important contribution of scientists and educators to achieving its goals, the science that underpins the Chemical Weapons Convention, and how scientific and technological advances will help to better implement the Convention in the future.The OPCW is the implementing body for Chemical Weapons Convention, an international disarmament treaty banning chemical weapons. The organisation is now approaching the 20th anniversary of the entry into force of the Chemical Weapons Convention in 1997. Twenty years that have seen the destruction of more than 67 000 metric ton of the world’s declared military stockpiles of chemical weapons and a Nobel Peace Prize in 2013. With 192 States Parties (the governments that have agreed to uphold the norms and obligations required by the treaty), the Chemical Weapons Convention is the most widely subscribed disarmament treaty in history.Despite the aforementioned successes, the OPCW is not widely recognized outside disarmament-focused diplomatic circles. This is in spite of the fact that the science of chemistry played a critical role in informing the negotiations that lead to the signing of the Chemical Weapons Convention, and underpinning the articles of implementation. Science represents an important dimension in international disarmament policy and diplomacy, requiring that organizations like the OPCW interact with the scientific communities – especially in the field of chemistry. In order to achieve its goals in the future, the OPCW will need to reach out to new stakeholders and strengthen its ties with its existing partners. To this end, the OPCW has been placing increasing priority on education and engagement to raise awareness of its work and the contributions both from and to science in chemical disarmament.The objective of this internationally open access ConfChem online conference was to bring forth educational material that could usefully introduce chemistry educators and students to the nexus of science and multilateral diplomacy in chemical disarmament. To this end, we introduce the seven papers of the ConfChem and their authors. We hope you enjoy this collection of papers at the intersection of science and international disarmament policy. A collection that looks to stimulate interest in the role of scientists and educators, especially chemists in making the world a safer place.


2021 ◽  
Vol 1 (3) ◽  
pp. 216-226
Author(s):  
Shahin Ayazi

Manometric assessment of the gastroesophageal junction (GEJ) and esophageal body is the key to a better understanding of the mechanics of antireflux surgery (ARS) and maximizing its benefits while minimizing adverse outcomes. However, there is an attitude of uncertainty regarding the necessity of esophageal motility prior to ARS among some surgeons. This evidence-based review highlights the critical role of manometry in the preoperative workup for patients undergoing ARS. It also discusses how manometry can detect findings associated with favorable outcomes or the risk of postoperative dysphagia. Manometric data can be used for risk stratification and the prediction of outcomes, aiding the surgeon in matching an operation to the specific physiology of each individual patient.


2021 ◽  
Vol 7 (2) ◽  
pp. 59-62
Author(s):  
Karen Vasquez-Avila ◽  
Kevin Pacheco-Barrios ◽  
Paulo Sampaio de Melo ◽  
Felipe Fregni

2020 ◽  
Vol 5 (1) ◽  
pp. 176-187
Author(s):  
Vahid Zeynvand Lorestani

This research aims to investigate the critical role of the Internet of Things in the future of industries’ progress. For this purpose, a survey of 250 top managers across 13 industries has conducted. The objective was to find their view of point about what short and mega trends, in which sector will have the most considerable influence in the five years as well as 30 years ahead. Moreover, various technologies are also identified that will have the most importance in the future according to the majority of the respondents, such as Internet of things, Automation and Artificial Intelligence, and, on the other hand, the segments that capital expenditure is currently being directed towards, such as Energy Efficiency and Personalisation of Services.


2021 ◽  
Vol 3 (2) ◽  
pp. 10-17
Author(s):  
Patrice Nicholas ◽  
Clara Gona ◽  
Linda Evans ◽  
Eleonor Pusey Reid

The US National Academy of Medicine released its consensus study for the next decade entitled The Future of Nursing 2020-2030: Charting a Path To Achieve Health Equity (National Academies of Sciences, Engineering, and Medicine, 2021). This paper examines the report, its implications for nursing globally, its focus on systemic, structural, and institutional racism, and the intersection with climate change and deleterious health consequences. The National Academies of Science, Engineering, and Medicine (NASEM) has led in addressing the critical role of the nursing profession in achieving optimal population health outcomes in the US. Yet, relevance exists for nursing in other global areas. The most recent US report focuses on social determinants of health (SDoH) and explicitly addresses climate change as a looming public health threat. An analysis of the key foci of nursing’s role in climate change amidst the critical role of health equity globally is explicated.  


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