scholarly journals PHYSICAL ACTIVITY TO IMPROVE THE PHYSIOLOGICAL INDEX OF CARDIOVASCULAR EFFECT

2021 ◽  
Vol 27 (8) ◽  
pp. 773-775
Author(s):  
Mei Qin ◽  
Cunshan Peng ◽  
Qingke Wang
Keyword(s):  
Physical Exercise ◽  
Vascular Function ◽  
Blood Circulation ◽  
Exercise Prescription ◽  
Critical Role ◽  
Level Of Evidence ◽  
Physiological Indicators ◽  
Lung Capacity ◽  
Contractility Of The Heart

ABSTRACT Introduction: Physical exercise can enhance the body's ability to adapt to the external environment and improve the contractility of the heart. At the same time, it can help improve blood circulation and increase lung capacity. Objective: This article explores the critical role of sports in the prevention of cardiovascular diseases. Methods: This article conducts tests on related physiological indicators such as hemodynamic rheology for students who regularly participate in physical exercise and those who do not participate in physical exercise. Results: Students who exercise regularly and those who do not exercise mobilize faster cardiovascular function at the beginning of work. This shows good adaptability to sports. Conclusion: The use of fitness exercise prescription by students who exercise comprehensively has the most pronounced effect on improving vascular function. Level of evidence II; Therapeutic studies - investigation of treatment results.

Bridging the Knowledge Gaps in Arrhythmogenic Cardiovascular Conditions: The Critical Role of Registries

2016 ◽  
Vol 10 (2) ◽  
pp. 1 ◽  
Author(s):  
Melody Hermel ◽  
Rebecca Duffy ◽  
Alexander Orfanos ◽  
Isabelle Hack ◽  
Shayna McEnteggart ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Natural History ◽  
Risk Stratification ◽  
Critical Role ◽  
Knowledge Gaps ◽  
Level Of Evidence ◽  
The Future

Cardiac registries have filled many gaps in knowledge related to arrhythmogenic cardiovascular conditions. Despite the less robust level of evidence available in registries when compared with clinical trials, registries have contributed a range of clinically useful information. In this review, the authors discuss the role that registries have played – related to diagnosis, natural history, risk stratification, treatment, and genetics of arrhythmogenic cardiovascular conditions – in closing knowledge gaps, and their role in the future.

scholarly journals New Directions in Exercise Prescription: Is There a Role for Brain-Derived Parameters Obtained by Functional Near-Infrared Spectroscopy?

2020 ◽  
Vol 10 (6) ◽  
pp. 342 ◽  
Author(s):  
Fabian Herold ◽  
Thomas Gronwald ◽  
Felix Scholkmann ◽  
Hamoon Zohdi ◽  
Dominik Wyser ◽  
...  
Keyword(s):  
Infrared Spectroscopy ◽  
Physical Exercise ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Exercise Prescription ◽  
Brain Activity ◽  
Brain Health ◽  
Functional Near Infrared Spectroscopy ◽  
Internal Load

In the literature, it is well established that regular physical exercise is a powerful strategy to promote brain health and to improve cognitive performance. However, exact knowledge about which exercise prescription would be optimal in the setting of exercise–cognition science is lacking. While there is a strong theoretical rationale for using indicators of internal load (e.g., heart rate) in exercise prescription, the most suitable parameters have yet to be determined. In this perspective article, we discuss the role of brain-derived parameters (e.g., brain activity) as valuable indicators of internal load which can be beneficial for individualizing the exercise prescription in exercise–cognition research. Therefore, we focus on the application of functional near-infrared spectroscopy (fNIRS), since this neuroimaging modality provides specific advantages, making it well suited for monitoring cortical hemodynamics as a proxy of brain activity during physical exercise.

ISH ADA-01 Critical role of telomerase in regulating cerebral vascular function and redox environment

2016 ◽  
Vol 34 (Supplement 1) ◽  
pp. e39
Author(s):  
Karima Ait-Aissa ◽  
Joseph Hockenberry ◽  
David Gutterman ◽  
Aron Geurts ◽  
Andreas Beyer
Keyword(s):  
Vascular Function ◽  
Critical Role ◽  
Redox Environment ◽  
Cerebral Vascular

scholarly journals Deletion of Seipin Attenuates Vascular Function and the Anticontractile Effect of Perivascular Adipose Tissue

2021 ◽  
Vol 8 ◽  
Author(s):  
Mengyu Wang ◽  
Junhui Xing ◽  
Mengduan Liu ◽  
Mingming Gao ◽  
Yangyang Liu ◽  
...  
Keyword(s):  
Endoplasmic Reticulum ◽  
Adipose Tissue ◽  
Vascular Function ◽  
Mesenteric Artery ◽  
Critical Role ◽  
Perivascular Adipose Tissue ◽  
Vascular Homeostasis ◽  
Lipid Droplet Formation ◽  
First Time

Seipin locates in endoplasmic reticulum (ER) and regulates adipogenesis and lipid droplet formation. Deletion of Seipin has been well-demonstrated to cause severe general lipodystrophy, however, its role in maintaining perivascular adipose tissue (PVAT) and vascular homeostasis has not been directly assessed. In the present study, we investigated the role of Seipin in mediating the anticontractile effect of PVAT and vascular function. Seipin expression in PVAT and associated vessels were detected by qPCR and western-blot. Seipin is highly expressed in PVAT, but hardly in vessels. Structural and functional alterations of PVAT and associated vessels were compared between Seipin−/− mice and WT mice. In Seipin−/− mice, aortic and mesenteric PVAT were significantly reduced in mass and adipose-derived relaxing factors (ADRFs) secretion, but increased in macrophage infiltration and ER stress, as compared with those in WT mice. Aortic and mesenteric artery rings from WT and Seipin−/− mice were mounted on a wire myograph. Vasoconstriction and vasodilation were studied in vessels with and without PVAT. WT PVAT augmented relaxation but not Seipin−/− PVAT, which suggest impaired anticontractile function in PVAT of Seipin−/− mice. Thoracic aorta and mesenteric artery from Seipin−/− mice had impaired contractility in response to phenylephrine (PHE) and relaxation to acetylcholine (Ach). In conclusion, Seipin deficiency caused abnormalities in PVAT morphology and vascular functions. Our data demonstrated for the first time that Seipin plays a critical role in maintaining PVAT function and vascular homeostasis.

scholarly journals Endothelial cells provide an instructive niche for the differentiation and functional polarization of M2-like macrophages

Blood ◽  
2012 ◽  
Vol 120 (15) ◽  
pp. 3152-3162 ◽  
Author(s):  
Huanhuan He ◽  
Jingying Xu ◽  
Carmen M. Warren ◽  
Dan Duan ◽  
Xinmin Li ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Vascular Function ◽  
Critical Role ◽  
Colony Growth ◽  
Hematopoietic Progenitors ◽  
Enhanced Expression ◽  
Functional Polarization ◽  
Functional Analyses

Abstract Endothelial cells and macrophages are known to engage in tight and specific interactions that contribute to the modulation of vascular function. Here we show that adult endothelial cells provide critical signals for the selective growth and differentiation of macrophages from several hematopoietic progenitors. The process features the formation of well-organized colonies that exhibit progressive differentiation from the center to the periphery and toward an M2-like phenotype, characterized by enhanced expression of Tie2 and CD206/Mrc1. These colonies are long-lived depending on the contact with the endothelium; removal of the endothelial monolayer results in rapid colony dissolution. We further found that Csf1 produced by the endothelium is critical for the expansion of the macrophage colonies and that blockade of Csf1 receptor impairs colony growth. Functional analyses indicate that these macrophages are capable of accelerating angiogenesis, promoting tumor growth, and effectively engaging in tight associations with endothelial cells in vivo. These findings uncover a critical role of endothelial cells in the induction of macrophage differentiation and their ability to promote further polarization toward a proangiogenic phenotype. This work also highlights some of the molecules underlying the M2-like differentiation, a process that is relevant to the progression of both developmental and pathologic angiogenesis.

HIGH INTENSITY SPORTS PROMOTE THE DEVELOPMENT OF HEALTHY BONE TISSUE

2021 ◽  
Vol 27 (7) ◽  
pp. 728-731
Author(s):  
Zhonghu Fu ◽  
Lijun Gao
Keyword(s):  
Physical Exercise ◽  
Physical Fitness ◽  
Bone Health ◽  
Questionnaire Survey ◽  
Treatment Results ◽  
School Students ◽  
Level Of Evidence ◽  
Skeletal Tissue ◽  
Physiological Indicators ◽  
The Impact

ABSTRACT Introduction: Physical exercise can promote the growth and development of bones and delay bone loss; it is more effective when started young. Objective: This paper analyzes the impact of human exercise on human bone health. Methods: A questionnaire survey was conducted on elementary school students, and basic physical fitness monitoring was conducted. The physical fitness monitoring indicators covered ten items such as height and weight. Results: After the questionnaire survey and physical examination, it was found that there are differences in various physiological indicators between students who exercise frequently compared with students who exercise less frequently. Conclusion: Physical exercise can promote skeletal tissue development, therefore, young people should increase the practice of physical exercise. Level of evidence II; Therapeutic studies - investigation of treatment results.

scholarly journals THE EFFECT OF PHYSICAL EXERCISE ON BLOOD SUGAR CONTROL IN DIABETIC PATIENTS

2021 ◽  
Vol 27 (3) ◽  
pp. 311-314
Author(s):  
Weilin Wang ◽  
Mengchun Huang ◽  
Junrong Wang
Keyword(s):  
Physical Exercise ◽  
Blood Sugar ◽  
Glycosylated Hemoglobin ◽  
Diabetic Patients ◽  
Level Of Evidence ◽  
Physiological Indicators ◽  
Glycosylated Hemoglobin Level ◽  
Treatment Of Diabetes ◽  
Sugar Levels ◽  
Exercise Status

ABSTRACT Introduction Diabetes is a metabolic disease characterized by hyperglycemia. It is a metabolic syndrome in which blood sugar levels increase due to defects in insulin secretion or impaired function, or even both defects. Object To understand the effect of diabetic patients in controlling blood sugar through physical exercise, the paper analyzes the correlation between the exercise status and physiological indicators of diabetic patients in our hospital. Methods We randomly selected 41 diabetic patients and monitored their exercise. At the same time, we check the physiological indicators of the patients after the exercise is completed and analyze the control of blood sugar by sports. Results After healthy physical exercise, the blood sugar level of diabetic patients tended to stabilize, and the glycosylated hemoglobin level decreased. The blood sugar levels of patients who did not participate in healthy physical exercises were not stable, and their glycosylated hemoglobin levels did not improve. Conclusion Healthy sports is a simple, easy, safe and effective adjuvant therapy for the prevention and treatment of diabetes, and it is worthy of clinical promotion. Level of evidence II; Therapeutic studies - investigation of treatment results.

scholarly journals EFFECTIVENESS OF PHYSICAL EXERCISE ON THE RECOVERY OF LIMB FUNCTION IN STROKE PATIENTS

2021 ◽  
Vol 27 (3) ◽  
pp. 262-265
Author(s):  
Jisheng Wang
Keyword(s):  
Physical Exercise ◽  
Aerobic Exercise ◽  
Exercise Group ◽  
Stroke Patients ◽  
Scoring Method ◽  
Limb Function ◽  
Level Of Evidence ◽  
Physical Strength ◽  
Physiological Indicators ◽  
Basic Ability

ABSTRACT Introduction Patients with cerebrovascular accident and hemiplegia need to perform physical exercise and aerobic training, but physical dysfunction restricts the performance of these activities. Objective The article aims to develop physical strength sports for stroke patients with hemiplegia to explore the efficacy of sports to regain limb function in these patients. Methods We randomly selected 30 patients with stroke sequelae and divided them into control and exercise groups. While undergoing rehab, the exercise group performed a certain amount of aerobic exercise. During this period, we compared the relevant physiological indicators of the patients, and, at the same time, we used the Fugle-Meyer motor function scoring method to assess limb function. Results The two groups of patients are significantly different regarding the recovery of physical function and the capacity for daily life. Physiological indicators of patients are also different. Conclusion Low-intensity aerobic exercise can help stroke and hemiplegia patients regain their basic ability to live and exercise. Level of evidence II; Therapeutic studies: investigation of treatment results.

scholarly journals SCIENTIFIC PHYSICAL EXERCISE TO PREVENT MUSCLE INJURY IN COMPETITIVE SPORTS

2021 ◽  
Vol 27 (8) ◽  
pp. 789-792
Author(s):  
Delong Liu
Keyword(s):  
Physical Exercise ◽  
Tennis Elbow ◽  
Muscle Endurance ◽  
Competitive Sports ◽  
Sports Training ◽  
Muscle Injuries ◽  
Level Of Evidence ◽  
Physiological Indicators ◽  
Before And After ◽  
Therapy Interventions

ABSTRACT Introduction: Various factors cause many sports traumas in groups engaged in mass sports activities, amateur sports training, and professional sports training in China that must be called to our attention. Objective: Scientific Sports Therapy is a scientific and reasonable systemic sports training program formulated for competitive athletes based on their physical and disease characteristics. Methods: This article conducted scientific sports therapy interventions on tennis elbow patients and analyzed multiple physiological indicators such as muscle endurance before and after the intervention. Results: There are significant differences in the athletes’ muscle strength and muscle endurance data after physical exercise therapy. Conclusion: We analyzed the causes of muscle damage and adopted scientific and practical sports therapy. In this way, coaches and athletes can find effective ways to prevent and manage muscle injuries, thereby improving competitive sports training. Level of evidence II; Therapeutic studies - investigation of treatment results.

The Role of the SLP in Autism Spectrum Disorder Screening and Assessment

2008 ◽  
Vol 15 (2) ◽  
pp. 50-59 ◽  
Author(s):  
Amy Philofsky
Keyword(s):  
Language Development ◽  
Critical Role ◽  
Children With Autism ◽  
Autism Spectrum ◽  
Children With Asd ◽  
Prevalence Estimates ◽  
Notable Increase ◽  
Screening Assessment ◽  
Critical Components

AbstractRecent prevalence estimates for autism have been alarming as a function of the notable increase. Speech-language pathologists play a critical role in screening, assessment and intervention for children with autism. This article reviews signs that may be indicative of autism at different stages of language development, and discusses the importance of several psychometric properties—sensitivity and specificity—in utilizing screening measures for children with autism. Critical components of assessment for children with autism are reviewed. This article concludes with examples of intervention targets for children with ASD at various levels of language development.

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