Efecto del aceite esencial de orégano sobre el desempeño productivo de ponedoras y la estabilidad oxidativa de huevos enriquecidos con ácidos grasos poliinsaturados

This study evaluated the inclusion of oregano essential oil (OEO, Lippia origanoides Kunth) in diets enriched with polyunsaturated fatty acids (PUFAs) on productive performance of laying hens, lipid profile and oxidative stability of eggs during storage. 144 hens were distributed in one of four treatments with six replicates in order to evaluate the effect of the type of oil used in the diet (palm or fish) and the inclusion of OEO on the production variables, along with the ethereal extract, lipid profile and malonaldehyde concentration (MDA), using a completely randomized factorial design with the repeated measures of days of storage (0, 30 and 60 days at 4° C). Results show that the type of oil and the OEO did not affect productive performance of layers (P > 0.05). PUFA concentration increased in 16.8% in diets with fish oil in 16.8%, where the DHA also increased by1.4% (P < 0.05), increasing the MDA concentration in egg (MDA 41.6 ng/g yolk), while supplementation of OEO at a level of 100 g/ton improved oxidative stability during storage (MDA 31.1 ng/g yolk). During storage the concentration of MDA in the yolk increased with time reaching 38 ng/g yolk at 60 days. The OEO showed potential as a natural antioxidant in the diet of layers hens improving the oxidative stability of eggs stored at 4°C up to 60 days.

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Effect of dietary source of very long chain n-3 polyunsaturated fatty acids on their concentrations in the edible tissues of the chicken

Proceedings of the British Society of Animal Science ◽

10.1017/s1752756200019190 ◽

2007 ◽

Vol 2007 ◽

pp. 16-16

Author(s):

R.A. Gibbs ◽

C. Rymer ◽

D.I. Givens

Keyword(s):

Fatty Acids ◽

Polyunsaturated Fatty Acids ◽

Fish Oil ◽

Oxidative Stability ◽

Chicken Meat ◽

Edible Tissues ◽

Broiler Diet ◽

Alternative Sources ◽

Different Sources ◽

Long Chain

The benefits to human health from consuming the very long chain n-3 polyunsaturated fatty acids (VLC n-3 PUFA) 20:5 (EPA) and 22:6 (DHA) are well known. In the human diet, oil-rich fish is a key source of VLC n-3 PUFA but fish consumption is so low that VLC n-3 PUFA intake is well below the minimum recommended. Other vehicles for increasing dietary supply have been explored and chicken meat is a potentially important contributor to human intakes if it is enriched with VLC n-3 PUFA, as it is responsive to dietary manipulation and is widely consumed. Enrichment of chicken meat can be achieved by supplementing the diets of growing birds with fish oil. However, reliance upon fish oil for this purpose is potentially unsustainable and the meat that is produced is more susceptible to constraints associated with its oxidative stability and organoleptic properties. Alternative sources of these fatty acids include marine algae (the primary producers of VLC n-3 PUFA) and fish oil encapsulated in a gelatin capsule. Both of these alternatives may increase the VLC n-3 PUFA content of the meat and also enhance its oxidative stability compared with meat that has been enriched by the inclusion of fish oil in the broiler diet. The objective of this study was to compare different sources of VLC n-3 PUFA in the broiler diet in relation to their effects on EPA and DHA concentration of the white and dark meat of the chicken.

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Hypercholesterolaemia alters the responses of the plasma lipid profile and inflammatory markers to supplementation of the diet with n-3 polyunsaturated fatty acids from fish oil

European Journal of Clinical Investigation ◽

10.1111/j.1365-2362.2006.01726.x ◽

2006 ◽

Vol 36 (11) ◽

pp. 788-795 ◽

Cited By ~ 6

Author(s):

E. Bravo ◽

M. Napolitano ◽

I. Lopez-Soldado ◽

M. Valeri ◽

K. M. Botham ◽

...

Keyword(s):

Fatty Acids ◽

Polyunsaturated Fatty Acids ◽

Fish Oil ◽

Lipid Profile ◽

Inflammatory Markers ◽

Plasma Lipid ◽

Plasma Lipid Profile

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Oregano essential oil supplementation improves productive performance, oxidative stability, and lipid parameters in turkeys

Scientia Agropecuaria ◽

10.17268/sci.agropecu.2020.02.05 ◽

2020 ◽

Vol 11 (2) ◽

pp. 187-193

Author(s):

Gilmar Mendoza-Ordoñez ◽

Luis Caceda-Gallardo ◽

Bruno Loyaga-Cortéz ◽

Roberto Ybañez-Julca ◽

Diego Gonzales-Nonato ◽

...

Keyword(s):

Essential Oil ◽

Oxidative Stability ◽

Productive Performance ◽

Oregano Essential Oil ◽

Lipid Parameters

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Beyond Fish Oil Supplementation: The Effects of Alternative Plant Sources of Omega-3 Polyunsaturated Fatty Acids upon Lipid Indexes and Cardiometabolic Biomarkers—An Overview

Nutrients ◽

10.3390/nu12103159 ◽

2020 ◽

Vol 12 (10) ◽

pp. 3159 ◽

Cited By ~ 1

Author(s):

Heitor O. Santos ◽

James C. Price ◽

Allain A. Bueno

Keyword(s):

Fatty Acids ◽

Polyunsaturated Fatty Acids ◽

Fish Oil ◽

Lipid Profile ◽

Omega 3 ◽

Alpha Linolenic Acid ◽

Global Challenge ◽

Cardiometabolic Markers ◽

Fish Oil Supplementation ◽

Plant Sources

Cardiovascular diseases remain a global challenge, and lipid-associated biomarkers can predict cardiovascular events. Extensive research on cardiovascular benefits of omega-3 polyunsaturated fatty acids (n3-PUFAs) is geared towards fish oil supplementation and fish-rich diets. Nevertheless, vegetarianism and veganism are becoming more popular across all segments of society, due to reasons as varied as personal, ethical and religious values, individual preferences and environment-related principles, amongst others. Due to the essentiality of PUFAs, plant sources of n3-PUFAs warrant further consideration. In this review, we have critically appraised the efficacy of plant-derived n3-PUFAs from foodstuffs and supplements upon lipid profile and selected cardiometabolic markers. Walnuts and flaxseed are the most common plant sources of n3-PUFAs, mainly alpha-linolenic acid (ALA), and feature the strongest scientific rationale for applicability into clinical practice. Furthermore, walnuts and flaxseed are sources of fibre, potassium, magnesium, and non-essential substances, including polyphenols and sterols, which in conjunction are known to ameliorate cardiovascular metabolism. ALA levels in rapeseed and soybean oils are only slight when compared to flaxseed oil. Spirulina and Chlorella, biomasses of cyanobacteria and green algae, are important sources of n3-PUFAs; however, their benefits upon cardiometabolic markers are plausibly driven by their antioxidant potential combined with their n3-PUFA content. In humans, ALA is not sufficiently bioconverted into eicosapentaenoic and docosahexaenoic acids. However, evidence suggests that plant sources of ALA are associated with favourable cardiometabolic status. ALA supplementation, or increased consumption of ALA-rich foodstuffs, combined with reduced omega-6 (n6) PUFAs intake, could improve the n3/n6 ratio and improve cardiometabolic and lipid profile.

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Effects of Fish Oil with a High Content of n-3 Polyunsaturated Fatty Acids on Mouse Gut Microbiota

Archives of Medical Research ◽

10.1016/j.arcmed.2014.03.008 ◽

2014 ◽

Vol 45 (3) ◽

pp. 195-202 ◽

Cited By ~ 82

Author(s):

Hai-Ning Yu ◽

Jing Zhu ◽

Wen-sheng Pan ◽

Sheng-Rong Shen ◽

Wei-Guang Shan ◽

...

Keyword(s):

Fatty Acids ◽

Gut Microbiota ◽

Polyunsaturated Fatty Acids ◽

Fish Oil ◽

Mouse Gut Microbiota

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Oxidative Stability of Polyunsaturated Fatty Acids in an Aqueous Dispersion.

Nippon Shokuhin Kagaku Kogaku Kaishi ◽

10.3136/nskkk.43.1079 ◽

1996 ◽

Vol 43 (10) ◽

pp. 1079-1085 ◽

Cited By ~ 5

Author(s):

Kazuo MIYASHITA

Keyword(s):

Fatty Acids ◽

Polyunsaturated Fatty Acids ◽

Oxidative Stability ◽

Aqueous Dispersion

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Apoptosis mediated chemosensitization of tumor cells to 5-fluorouracil on supplementation of fish oil in experimental colon carcinoma

Tumor Biology ◽

10.1177/1010428317695019 ◽

2017 ◽

Vol 39 (3) ◽

pp. 101042831769501 ◽

Cited By ~ 10

Author(s):

Isha Rani ◽

Bhoomika Sharma ◽

Sandeep Kumar ◽

Satinder Kaur ◽

Navneet Agnihotri

Keyword(s):

Fatty Acids ◽

Dna Damage ◽

Polyunsaturated Fatty Acids ◽

Fish Oil ◽

Tumor Cells ◽

Apoptotic Index ◽

Apoptotic Pathway ◽

Apoptotic Effect ◽

Underlying Mechanisms ◽

Apoptotic Pathways

5-Fluorouracil has been considered as a cornerstone therapy for colorectal cancer; however, it suffers from low therapeutic response rate and severe side effects. Therefore, there is an urgent need to increase the clinical efficacy of 5-fluorouracil. Recently, fish oil rich in n-3 polyunsaturated fatty acids has been reported to chemosensitize tumor cells to anti-cancer drugs. This study is designed to understand the underlying mechanisms of synergistic effect of fish oil and 5-fluorouracil by evaluation of tumor cell–associated markers such as apoptosis and DNA damage. The colon cancer was developed by administration of N,N-dimethylhydrazine dihydrochloride and dextran sulfate sodium salt. Further these animals were treated with 5-fluorouracil, fish oil, or a combination of both. In carcinogen-treated animals, a decrease in DNA damage and apoptotic index was observed. There was also a decrease in the expression of Fas, FasL, caspase 8, and Bax, and an increase in Bcl-2. In contrast, administration of 5-fluorouracil and fish oil as an adjuvant increased both DNA damage and apoptotic index by activation of both extrinsic and intrinsic apoptotic pathways as compared to the other groups. The increased pro-apoptotic effect by synergism of 5-fluorouracil and fish oil may be attributed to the incorporation of n-3 polyunsaturated fatty acids in membrane, which alters membrane fluidity in cancer cells. In conclusion, this study highlights that the induction of apoptotic pathway by fish oil may increase the susceptibility of tumors to chemotherapeutic regimens.

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