Influence of Sediment Properties on Low-Frequency Electric-Joule-Heating Process in Class 1 Hydrate Deposits

Author(s):  
Ermeng Zhao ◽  
Jian Hou ◽  
Yunkai Ji ◽  
Lu Liu ◽  
Yongge Liu
2010 ◽  
Vol 445 ◽  
pp. 225-228
Author(s):  
Yoshihiro Takahashi ◽  
Hirokazu Masai ◽  
Takumi Fujiwara ◽  
Minoru Osada

In-situ observation of inelastic light scattering of boson region in glassy Ba2TiGe2O8 (BTG) was performed during heating process. The in-situ boson observation revealed structural relaxation below glass-transition temperature in the as-quenched sample, suggesting the nanometric structural heterogeneity. Relation of the boson behavior to crystallization tendency is also discussed.


1986 ◽  
Vol 113 (2) ◽  
pp. 268-271 ◽  
Author(s):  
Jun Takeda ◽  
Yutaka Seino ◽  
Hirofumi Fukumoto ◽  
Gyohan Koh ◽  
Akio Otsuka ◽  
...  

Abstract. Polymorphism of 5' portion of the human insulin gene was examined in 188 unrelated Japanese subjects (49 normal, 71 with IDDM, and 68 with NIDDM) using restriction endonuclease analysis. Restriction fragments were classified according to the insertion size: Class 1 (600 base pairs), Class 2 (1300 base pairs), and Class 3 (2000 base pairs). We found a very high frequency of Class 1 alleles (96.8%) and a low frequency of both Class 2 (0.8%) and Class 3 alleles (2.4%) and that approximately 94% of the genotypes were Class 1/Class 1 homozygote. In addition, there was no correlation of allelic or genotypic frequency with NIDDM or IDDM. We conclude that length polymorphism of the human insulin gene cannot be a useful marker for diabetes in Japanese.


2019 ◽  
Vol 203 ◽  
pp. 110156 ◽  
Author(s):  
Jian Huang ◽  
Yurong He ◽  
Yanwei Hu ◽  
Xinzhi Wang

1982 ◽  
Vol 2 (9) ◽  
pp. 1126-1133 ◽  
Author(s):  
A E Simon ◽  
M W Taylor ◽  
W E Bradley ◽  
L H Thompson

We present evidence for a two-step model for expression of the recessive phenotype at the diploid adenine phosphoribosyl transferase (aprt) locus in Chinese hamster ovary cells. This model proposes a high-frequency event leading to allelic inactivation and a low-frequency event leading to a structural alteration of the APRT protein. Either event can occur first, resulting in two types of heterozygous cells. The proposed model is based on analysis of Chinese hamster ovary presumptive aprt heterozygotes and APRT- mutants, derived by two different laboratories. The major class of heterozygotes (class 1) had approximately 50% parental APRT activity, 50% immunologically precipitable APRT protein, and only wild-type enzyme as based on two-dimensional gel electrophoresis and thermal inactivation studies. We propose that one allele at the aprt locus has been inactivated in these heterozygotes. APRT- mutants derived from any single class 1 heterozygote arose at a low frequency and contained either no immunologically detectable APRT protein or an APRT enzyme which was, in most cases, demonstrably altered. The second class of heterozygotes, consisting of two independent isolates, gave rise to APRT- cells at a high frequency (10(-3) to 10(-5). These heterozygous cell lines had 50% of parental APRT activity and only wild-type spot, or wild-type and an electrophoretic variant spot, on two-dimensional gels. These aprt heterozygotes appear to have arisen by mutation at one allele. APRT- mutants derived from either heterozygote of this class had all lost the wild-type activity, consistent with the proposed model.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Elnaz Abbasi ◽  
Ehsanollah Ghaznavi-Rad

Abstract Background This study aimed to investigate the frequency and the antibiotic resistance patterns of Salmonella species that were isolated from infectious diarrhea samples taken from pediatric patients in central Iran. Methods The study analyzed 230 stool specimens that were cultured on XLD, MacConkey agar and GN broth. Polymerase chain reaction (PCR) assay was used to identify the Salmonella genus. The antibiotic resistance profiles and the frequency of quinolone and integron genes were obtained. Results Out of 230 samples of infectious diarrhea, 21 (9.1%) cases of Salmonella spp. were identified using culture methods. Another 28 (12.1%) samples had positive PCR results, with S. serovar Paratyphi B and C (9/21; 42.8%) and S. Typhi (3/21; 14.3%) being the most recognized. The highest antibiotic resistance rates were found for nalidixic acid (15/21; 71.4%), tetracycline (9/21; 42.8%). However, six (28.5%) of isolates were found resistant to cotrimoxazole, ampicillin and chloramphenicol. Among the plasmid-mediated quinolone resistance (PMQR) determinants, qnrS, qnrA, and qnrB were positive in (9/15; 60%), (6/15; 40%) and (3/15; 20%) of the isolates, respectively. Class 1 and 2 integrons were identified in 15 (71.4%) and 3 (14.3%) isolates, respectively. Conclusion High rates of quinolone resistant and low frequency of MDR Salmonella spp. isolates were identified in central Iran, similar to findings in other parts of Asia. To prevent the spread of these resistant strains, the antimicrobial resistance of Salmonella spp. isolates should be under constant surveillance, and empiric antibiotic therapy should be adapted appropriately.


2020 ◽  
Vol 3 (4) ◽  

Hepatic tumors occur in liver tissue due to the growth of malignant cells. Low-frequency Joule heating (LFJH) is one of the cancer treatment methods that show tremendous potential to treat hepatic cancer without causing excessive side effects or patient discomfort as other cancer treatments such as chemotherapy. In this localized thermal treatment method, the tumor in liver tissue is heated to a critical temperature range using radiofrequency (RF) energy designed to damage malignant cells. An electrode is introduced over the tumor and electric current is passed through it to induce Joule heating. The volume heat generation due to the Joule heating raises local temperature in tumor cells and causes complete destruction or damage. In this study, a computational simulation model is created based on coupled solution of bio heat equation and electrical field equation and considering a composite region of malignant tumor embedded in liver tissue region. The electrical and thermal fields that can cause damage to the malignant cells without affecting the surrounding tissue are determined and optimized by changing various controlling parameters such as electrode design, frequency, and amplitude of the RF energy


2020 ◽  
Vol 101 (5) ◽  
pp. 645-651
Author(s):  
E A Safronova ◽  
A I Kuzin ◽  
U V Kharlamova ◽  
T N Shamaeva ◽  
L V Ryabova

Aim. To study the effect of nitroglycerin on the heart rate and its variability in patients with stable angina pectoris class 1 and 2. Methods. 85 men with stable angina pectoris class 1 and 2 pathologies were examined between 2007 and 2012 in the City Clinical Hospital No. 8 of Chelyabinsk (mean age 53.15.66 years). In addition to common methods, a rhythmocardiographic study was performed, which allows you to calculate heart rate variability. An electrocardiogram was recorded simultaneously with the rhythmocardiogram. Results. After sublingual nitroglycerin, the number of ventricular extrasystoles decreased in the background test and during Valsalva maneuver, increased in the Ashner's test and an exercise stress tests and did not change in the orthostatic test. An increase in supraventricular extrasystoles after nitroglycerin administration occurred in 10.6% of patients. Nitroglycerin administration resulted in a decrease in the inter-systolic intervals, an increased in the proportion of slow low-frequency waves statistically significant in the background and an exercise stress test. Spectral indicators of cardiac sympathetic modulation significantly increased in the Ashners test and decreased in the background test, while spectral indicators of cardiac parasympathetic modulation decreased in all samples except in exercise stress tests. Conclusion. Under the influence of nitroglycerin, supraventricular arrhythmias increased in all vegetative tests except for orthostatic, the number/severity of ventricular extrasystoles ambiguously changed: decreased in Valsalva manoeuvre the background test, did not change in orthostatic and increased in Aschner's and an exercise stress tests; after nitroglycerin, the proportions of sympathetic influence (in Ashner's test) and slow low-frequency waves in the spectrum of the vegetative modulation increased with a decrease in parasympathetic.


2022 ◽  
Vol 13 (1) ◽  
Author(s):  
Bing Deng ◽  
Zhe Wang ◽  
Weiyin Chen ◽  
John Tianci Li ◽  
Duy Xuan Luong ◽  
...  

AbstractNanoscale carbides enhance ultra-strong ceramics and show activity as high-performance catalysts. Traditional lengthy carburization methods for carbide syntheses usually result in coked surface, large particle size, and uncontrolled phase. Here, a flash Joule heating process is developed for ultrafast synthesis of carbide nanocrystals within 1 s. Various interstitial transition metal carbides (TiC, ZrC, HfC, VC, NbC, TaC, Cr2C3, MoC, and W2C) and covalent carbides (B4C and SiC) are produced using low-cost precursors. By controlling pulse voltages, phase-pure molybdenum carbides including β-Mo2C and metastable α-MoC1-x and η-MoC1-x are selectively synthesized, demonstrating the excellent phase engineering ability of the flash Joule heating by broadly tunable energy input that can exceed 3000 K coupled with kinetically controlled ultrafast cooling (>104 K s−1). Theoretical calculation reveals carbon vacancies as the driving factor for topotactic transition of carbide phases. The phase-dependent hydrogen evolution capability of molybdenum carbides is investigated with β-Mo2C showing the best performance.


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