Peculiarities of the uterine contractile activity in pregnant with mild preeclampsia at labor

2017 ◽  
pp. 69-72
Author(s):  
N.V. Abbasova ◽  
◽  
E.M. Aliyeva ◽  
V.A. Akhmed-zade ◽  
A.Dj. Ismailova ◽  
...  
Keyword(s):  
Key Words ◽  
Clinical Manifestation ◽  
Contractile Activity ◽  
Total Duration ◽  
Active Phase ◽  
Labor Time ◽  
Uterine Contractile ◽  
Mild Preeclampsia ◽  
Total Labor ◽  
Latent Phase

The objective: to study the contractile activity of the uterus in pregnant with mild preeclampsia at labor. Patients and methods. Was studies contractile activity of the uterus during the labor in 93 pregnant with mild preeclampsia. The average age of women was 25.24±0.42 (17–37 years). The duration of the clinical manifestation of mild preeclampsia was 3.2±0.1 (1 week). The contractile activity of the uterus was evaluated by the method of external cardiotocography. Results.There was confirmed, that pregnant with mild preeclampsia had high indicators of uterine contractile activity at the latent phase, including intense of the cramps 43.78±2.32 mm Hg , duration of the cramps – 28.32±1.1 s, dutation of relaxation – 43.44±1.46 s, total duration of the cramps – 71.76±1.27 s, duration of the uterine cycle – 66.55±0.28 s. And this leads to significant decreasing of the duration of the latent phase 1.24±0.11 hour, and decreasing of the total labor time (9.18±0.22 hours) appropriately. Conclusion. In parturient women with mild preeclampsia, high rates of contractile activity of the uterus in the latent phase, what significantly reduce the duration of the latent phase, and the total duration of labor as well. Key words: mild preeclampsia, contractile activity of the uterus, latent phase of the labor, active phase of the labor, intranatal cardiotocography.

361: Risk of cesarean delivery during the active phase of labor and uterine contractile activity

2018 ◽  
Vol 218 (1) ◽  
pp. S224
Author(s):  
Heather A. Frey ◽  
Candice L. Woolfolk ◽  
Antonina Frolova ◽  
Joshua Rosenbloom ◽  
George A. Macones ◽  
...  
Keyword(s):  
Cesarean Delivery ◽  
Contractile Activity ◽  
Active Phase ◽  
Uterine Contractile

scholarly journals Role of biologically active molecules in uterine contractile activity

2019 ◽  
Vol 68 (1) ◽  
pp. 21-27
Author(s):  
Tatyana U. Kuzminykh ◽  
Vera Yu. Borisova ◽  
Igor P. Nikolayenkov ◽  
Georgy R. Kozonov ◽  
Gulrukhsor Kh. Tolibova
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Synthase ◽  
Adhesion Molecules ◽  
Connexin 43 ◽  
Contractile Activity ◽  
Active Phase ◽  
Uterine Contractile ◽  
Uterine Inertia ◽  
Oxide Synthase

Hypothesis/aims of study. Myometrial relaxation and contraction require synchronous cellular interactions. At present, it has been established that the coordination of myometrial contractile activity is carried out by a conduction system constructed from gap junctions with intercellular channels. There are no clinical data on inhibiting (nitric oxide synthase) and activating (connexin-43) factors of uterine contractile activity in the myometrium during pregnancy and parturition in the published literature. This study was undertaken to measure the expression levels of nitric oxide synthase, adhesion molecules CD51, CD61, and connexin-43 in the myometrium during pregnancy and parturition; and to assess the role of inhibitory and activating factors in the development of uterine contractile activity. Study design, materials and methods. An immunohistochemical study of myometrial biopsy specimens obtained from the lower uterus segment during cesarean section was performed in eight women with a full-term physiological pregnancy, in another eight individuals in the active phase of uncomplicated parturition, and in eight patients with uterine inertia. Integrins (CD51 and CD61 proteins) were used as markers of cell adhesion. Localization and the number of intercellular contacts were assessed by measuring the expression level of connexin-43, with the intensity of oxidative processes assessed by nitric oxide synthase activity. Results. In the myometrium, in the active phase of physiological parturition, a three-fold increase in the expression of activating (CD51, CD61, and connexin-43) factors of uterine contractile activity and a five-fold decrease in that of inhibitory (nitric oxide synthase) ones occur compared to those in full-term physiological pregnancy. Conclusion. In the pathogenesis of uterine inertia and resistance to labor induction, an important role is played by the decreased expression of adhesion molecules (CD51, CD61) and connexin-43 and the increased expression of nitric oxide synthase in the myometrium.

OBTURATOR HERNIA: A CASE REPORT

2016 ◽  
pp. 106-109
Author(s):  
Hoang Minh Thi Nguyen ◽  
Huu Tri Nguyen ◽  
Thanh Thao Nguyen
Keyword(s):  
Computed Tomography ◽  
Case Report ◽  
Intestinal Obstruction ◽  
Key Words ◽  
Clinical Manifestation ◽  
Elderly Women ◽  
Obturator Hernia ◽  
Abdominal Hernia ◽  
Mechanical Obstruction

Obturator hernia is a rare pelvic hernia which accounts for 1% of all abdominal hernia. Clinical manifestation is ussually unspecific. Obturator hernia is often diagnosed by computed tomography or ultrasound. We present a case of obturator hernia in an elderly women who was successfully diagnosed and treated at Hue Univeristy of Medicine and Pharmacy. Key words: obturator hernia, mechanical obstruction, intestinal obstruction, Richter obturator hernia, strangulation

DZIKIR CAN REDUCE LABOR PAIN LEVEL

2021 ◽  
Vol 2 (1) ◽  
pp. 26-30
Author(s):  
Ai Nur Zannah
Keyword(s):  
Physiological Condition ◽  
Active Phase ◽  
Labor Pain ◽  
Pain Level ◽  
Cervical Dilation ◽  
Uterine Contractions ◽  
Before And After ◽  
Quasi Experimental ◽  
Latent Phase ◽  
First Stage Of Labor

Labor pain is a physiological condition that began at the first stage of labor (laten and active phase). Pain comes from uterine contractions and cervical dilation in an attempt to pave the way for birth and encourage babies to be born. Experts find pharmacological and non-pharmacological ways to reduce pain in labor, one of them is Dzikir guided by childbirth helper (midwife). The purpose of this study was to analyze the differences of labor pain level on mother in latent phase before and after applying Dzikir. Subjects were 15 accidentally selected mothers in labor latent phase on March - April in PMB “S” Puger Jember. The design of this study uses a quasi-experimental one group pre-posttest. Results showed significant decreased pain level of mothers after doing Dzikir significantly (Z=-3,578, p≤0.001). In conclusions, there are differences of labor pain level on mother in latent phase before and after applying Dzikir

Uterine contractile activity and fetal outcome in rats treated with vitamin C during late gestational variable stress exposure

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Shakiru A. Salami ◽  
Hussein M. Salahdeen ◽  
Abidemi E. Obafemi ◽  
Babatunde A. Murtala
Keyword(s):  
Vitamin C ◽  
Stress Responses ◽  
Contractile Activity ◽  
Exposed Group ◽  
Magnesium Ions ◽  
Uterine Contractility ◽  
Contractile Responses ◽  
Uterine Contractile ◽  
Vitamin C Supplementation

Abstract Objectives Stress responses vary throughout pregnancy and impact of late gestational variable stress (LGVS) with vitamin C supplementation on uterine contractility is barely explored. This study investigates fetal weight outcome and in-vitro uterine contractile responses to pharmacological agents during LGVS exposure. Methods Twenty four nulliparous pregnant rats were divided into four groups of six. During gestation days 10–19, groups 1 & 2 received normal saline and vitamin C (10 mg/kg) respectively. Groups 3 and 4 were exposed to stress (sleep deprivation, predator exposure, immobility, rapid cage changes, noise, and foreign object) with group 4 concurrently supplemented with vitamin C (10 mg/kg). Serum cortisol, oxidative bio-markers, fetal weights and in-vitro contractile responses of excised uterine tissue to acetylcholine (Ach), oxytocin, calcium chloride (CaCl2), potassium chloride (KCl), diclofenac, and magnesium ions were determined. Results Malondialdehyde activity and cortisol were significantly increased in variable stress only exposed group when compared with control and vitamin C supplemented groups. Fetal body weights, superoxide dismutase and catalase activity were significantly reduced in variable stress only exposed group. Significantly impaired contractile responses to Ach, CaCl2 & KCl in variable stress only exposed group were modulated in vitamin C supplemented groups. Impaired contractile response to oxytocin was however not reversed. Relaxation responses to diclofenac and magnesium ions were statistically unaltered across groups. Conclusions Impaired fetal weights and uterine contractile activity to Ach, CaCl2 and KCl during LGVS was modulated by vitamin C supplementation. Impaired oxytocin contractile activity was however unreversed.

scholarly journals Impact factors on fetal descent rates in the active phase of labor: a retrospective cohort study

2018 ◽  
Vol 46 (6) ◽  
pp. 579-585 ◽  
Author(s):  
Nina Kimmich ◽  
Jana Juhasova ◽  
Christian Haslinger ◽  
Nicole Ochsenbein-Kölble ◽  
Roland Zimmermann
Keyword(s):  
Cohort Study ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Total Duration ◽  
Active Phase ◽  
University Hospital ◽  
Impact Factors ◽  
Nulliparous Women ◽  
Vaginal Deliveries ◽  
Multiparous Women

Abstract Aim: To assess fetal descent rates of nulliparous and multiparous women in the active phase of labor and to evaluate significant impact factors. Methods: In a retrospective cohort study at the University Hospital of Zurich, Switzerland, we evaluated 6045 spontaneous vaginal deliveries with a singleton in vertex presentation between January 2007 and July 2014 at 34 0/7 to 42 0/7 gestational weeks. Median fetal descent rates and their 10th and 90th percentiles were assessed in the active phase of labor and different impact factors were evaluated. Results: Fetal descent rates are exponentially increasing. Nulliparous women have slower fetal descent than multiparous women (P<0.001), ranging from 0 to 5.81 cm/h and from 0 to 15 cm/h, respectively. The total duration of fetal descent in labor is 5.42 h for nulliparous and 2.71 h for multiparous women. Accelerating impact factors are a lower fetal station, multiparity, increasing maternal weight and fetal occipitoanterior position, whereas epidural anesthesia decelerates fetal descent (P<0.001). Conclusions: Fetal descent is a hyperbolic increasing process with faster descent in multiparous women compared to nulliparous women, is highly inter individual and is associated with different impact factors. The diagnosis of labor arrest or prolonged labor should therefore be based on such rates as well as on individual evaluation of every parturient.

Effects of physical exercise on colonic motor activity

1991 ◽  
Vol 260 (4) ◽  
pp. G646-G652 ◽  
Author(s):  
M. Dapoigny ◽  
S. K. Sarna
Keyword(s):  
Physical Exercise ◽  
Motor Activity ◽  
Contractile Activity ◽  
Total Duration ◽  
Distal Colon ◽  
Proximal Colon ◽  
Fed State ◽  
Fasted State ◽  
Colonic Motor ◽  
Colonic Motor Activity

We investigated the effect of physical exercise on colonic motor activity in the fasted and fed states in six conscious dogs. Each dog was implanted with nine strain gauge transducers: three on the proximal, three on the middle, and three on the distal colon. The dogs ran for 1 h on a treadmill at 5 km/h (slope 5%). In the fasted state, the dogs exercised during the 5th h of recording after an overnight fast, and in the fed state during the 1st, 3rd, and 5th postprandial hour. In the fasted state, exercise significantly decreased the frequency of colonic migrating motor complexes (MMCs) but had no effect on the total or the mean duration of contractile states in the proximal, middle, and distal colon. Postprandially, exercise disrupted colonic MMCs and replaced them with nonmigrating motor complexes in all three periods of exercise (1st, 3rd, and 6th h). Exercise also increased the total duration per hour of contractile activity throughout the colon during the 1st and 3rd h and only in the distal colon during the 6th h after the meal. The dogs never defecated during rest in the fasted or the fed state. Shortly after the start of exercise in the fasted and fed states, giant migrating contractions (GMCs) occurred, and they were followed by defecation. In approximately 40% of the experiments, another GMC originated in the proximal colon, approximately 10 min after the first defecation, and migrated caudad up to the middle colon. These GMCs were not associated with defecation but caused mass movements.(ABSTRACT TRUNCATED AT 250 WORDS)

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