scholarly journals Information Technologies of Digital Adaptive Medicine

2021 ◽  
Vol 20 (5) ◽  
pp. 1154-1182
Author(s):  
Alexey Bogomolov
Keyword(s):  
Information Processing ◽  
Information Technologies ◽  
Life Support ◽  
The Body ◽  
Human Longevity ◽  
Professional Activity ◽  
Physical Factors ◽  
Processes And Reactions ◽  
Software Models ◽  
Adaptive Capabilities

The article provides a comprehensive description of information technologies of digital adaptive medicine. The emphasis is on the applicability to the development of specialized automated complexes, software models and systems for studying the adaptive capabilities of a person to environmental conditions. Requirements for information technologies to enhance these capabilities are formulated. The features of information technologies are reflected in relation to the implementation of applied systemic studies of life support, preservation of professional health and prolongation of human longevity. Six basic concepts of adaptive medicine with an emphasis on the features of the mathematical support for information processing are characterized, priorities for improving information technologies used in these concepts are determined. The information technologies used in the tasks of ensuring the professional performance of a person with an emphasis on the need to use adequate methods for diagnosing the state of a person at all stages of professional activity and the need to develop technologies for digital twins that adequately simulate the adaptation processes and reactions of the body in real conditions are considered. The characteristics of information technologies for personalized monitoring of health risks are given, which make it possible to objectify the effects of physical factors of the conditions of activity and to implement individual and collective informing of personnel about environmental hazards. The urgent need to standardize information processing methods in the development of information technologies for digital adaptive medicine in the interests of ensuring physiological adequacy and mathematical correctness of approaches to obtaining and processing information about a person's state is shown. It is concluded that the priorities for improving information technologies of digital adaptive medicine are associated with the implementation of the achievements of the fourth industrial revolution, including the concept of sociocyberphysical systems.

Analysis of airmen disadaption factors after combat stress exposure

2020 ◽  
Vol 22 (3) ◽  
pp. 68-71
Author(s):  
A. M. Schegol’kov ◽  
A. A. Blaginin ◽  
A. Ya. Fisun ◽  
D. V. Cherkashin ◽  
R. G. Makiev ◽  
...  
Keyword(s):  
Nervous System ◽  
Negative Impact ◽  
The Body ◽  
Stress Factors ◽  
Traumatic Experience ◽  
Professional Activity ◽  
Combat Stress ◽  
Functional Disorders ◽  
Post Traumatic Stress ◽  
Adaptive Capabilities

Abstract. Factors of disadaptation of pilots after combat stress are analyzed as one of the main factors in the development of post-traumatic stress disorder. It was found that the effects of combat stress have a great impact on young, thin pilots, with a predominance of the parasympathetic division of the autonomic nervous system and a reduced basic metabolism of the body. The data obtained allow for early diagnosis and identification of functional disorders in pilots for their medical and psychological rehabilitation. The use of the proposed discriminant function can be divided into adapted and unadapted (differently processing traumatic experience), for the development of appropriate rehabilitation programs within their medical and psychological rehabilitation. The revealed decrease in the reserve capabilities of the Central nervous system and the adaptive capabilities of the body of pilots subsequently leads to a decrease in the reliability of the professional activity of the pilot with an increase in its physiological price. In terms of methodology, understanding the postponement of the negative impact of combat stress factors on the pilots body requires constant measures for early detection and correction of emerging functional disorders. The consequences of combat stress are considered as an integral reaction of the body to the complex impact of various factors of combat stress, which is manifested at the psychophysiological and somatic levels and leads to early disqualification of pilots for medical reasons.

scholarly journals Rehabilitation program for acute poisoning in a toxicological hospital

2021 ◽  
Vol 20 (2) ◽  
pp. 99-117
Author(s):  
Yuri S. Goldfarb ◽  
Amayak V. Badalyan ◽  
Marina Yu. Marina ◽  
Vladislav A. Shchetkin ◽  
Mikhail M. Potskhveriya
Keyword(s):  
Functional Performance ◽  
Acute Poisoning ◽  
Rehabilitation Program ◽  
The Body ◽  
Medical Rehabilitation ◽  
Physical Factors ◽  
Duration Of Treatment ◽  
Severe Burns ◽  
Adaptive Capabilities ◽  
Snake Bites

BACKGROUND: Diagnostics and treatment of acute poisoning, as well as the rehabilitation measures carried out in relation to them, including the stationary stage, are aimed at the most complete restoration of the lost capabilities of the body. AIMS: Increasing the efficiency of medical rehabilitation of acute poisoning (AP) in a toxicological hospital through a combination of drug therapy and non-drug treatment with preformed physical factors. MATERIAL AND METHODS: Of 1,207 patients with AP psychopharmacological agents (pPFA), neurotoxicants (pNT), cauterizing agents (pCA) and snake bites (SB), who were in the toxicology department of the N.V. Sklifosovsky, 421 patients with an unfavorable course of AP were subjected to an in-depth examination. Intravenous laser hemotherapy (LGT), hyperbaric oxygenation (HBO), mesodiencephalic modulation (MDM), wave biomechanotherapy (WBMT) and ethylmethylhydroxypyridine succinate (EP) were used in cases of 291 patients of the main groups. RESULTS: The unfavorable course of AP was accompanied by an increase in the duration of treatment by 2.26.8 times due to the addition of pneumonia (pPFA), toxicohypoxic encephalopathy (pNT), severe burns of the gastrointestinal tract (pCA) and local edematous-inflammatory changes (SB). There was a syndrome of high blood viscosity and moderate endotoxicosis. The best clinical and laboratory results were obtained with a combination of LHT (90 minutes) with EP (pPFA), HBO and EP (pCA), HBO, MDM, EP (heavy pNT), HBO, EP (moderate pNT) and WBMT (SB). The adaptive capabilities of the organism, the state of the autonomic nervous system (pNT), neuropsychological indicators and electrical activity of the brain (pNT) improved. CONCLUSION: Programmed rehabilitation made it possible to achieve a noticeable reduction in the incidence of symptoms of the studied poisoning (by 54.693.4%), the time to resolve their manifestations (by 9.175%), as well as inpatient treatment (by 16.159.3%), improving functional performance.

PROSPECTS FOR THE DEVELOPMENT OF BANKING INFORMATION TECHNOLOGIES IN THE REPUBLIC OF UZBEKISTAN

2020 ◽  
Vol 9 (3) ◽  
pp. 33-38
Author(s):  
Iroda Abdullaeva ◽  
◽  
Dilyora Hoshimova ◽  
Hamdam Xomidov ◽  
Maftuna Raxmonova
Keyword(s):  
Information System ◽  
Information Processing ◽  
Information Systems ◽  
Information Technologies ◽  
The Republic

This article is devoted to the prospects of the development of banking information systems in the Republic of Uzbekistan and highlights issues such as the processing of significant flows of information in the banking information system using advanced information processing tools

STATE OF AUTONOMIC REGULATION OF HEART RHYTHM IN YOUNG AND AGED RATS BEFORE AND AFTER APPLICATION OF DIFFERENT REGIMENS OF RHYTHMIC EXTREME COOLING

2020 ◽  
pp. 436-443
Author(s):  
В. В. Кулик ◽  
В. Г. Бабийчук
Keyword(s):  
Heart Rate ◽  
Metabolic Regulation ◽  
Experimental Studies ◽  
Autonomic Regulation ◽  
The Body ◽  
Total Power ◽  
Aged Rats ◽  
Cooling Mode ◽  
Adaptive Capabilities ◽  
Extreme Cold

В работе изучено влияние разных режимов ритмических экстремальных холодовых воздействий на состояние вегетативной регуляции сердечного ритма у молодых и старых крыс. По данным спектрального анализа вариабельности сердечного ритма установлено, что у молодых крыс использование температурных режимов ритмических экстремальных холодовых воздействий, РЭХВ (-120 °С; -120 °С; -120 °С) и (-60 °С; -120 °С; -120 °С) значительно повышало адаптационные возможности организма за счет активации собственных гомеостатических регуляторных систем. При этом комбинированный режим РЭХВ (-60 °С; -120 °С; -120 °С) оказался наиболее оптимальным для старых животных, поскольку его применение не сопровождалось чрезмерной активацией симпатико-адреналовой системы на ранних этапах экспериментальных исследований в отличие от режима (-120 °С; -120 °С; -120 °С). Кроме того, использование данного режима охлаждения способствовало статистически значимому увеличению показателей общей мощности спектра нейрогуморальной регуляции не столько за счет повышения активности гуморально-метаболического звена регуляции, преобладание которого характерно для пожилого возраста, сколько благодаря увеличению тонуса вегетативных центров, причем парасимпатические влияния на миокард превалировали над симпатическими. The influence of various rhythmic extreme cold effects on the state of autonomic regulation of heart rate in young and aged rats was studied. According to the spectral analysis of heart rate variability, it has been found that in young rats, using rhythmic extreme cold exposures (RECE) temperature regimens of (-120 °С; -120 °С; -120 °С) and (-60 °С; -120 °С; -120 °С) significantly increased adaptive capabilities of the body due to the activation of its own homeostatic regulatory systems. At the same time, the combined regimen of RECE (-60 °С; -120 °С; -120 °С) occurred to be the most optimal for aged animals, since its use was not accompanied with an excessive activation of sympathoadrenal system at the early stages of experimental studies, in contrast to the regimen (-120 °С; -120 °С; -120 °С). In addition, the use of this cooling mode contributed to a statistically significant increase in the total power of spectrum of neurohumoral regulation not so much due to a rise in activity of humoral-metabolic regulation link, the prevalence of which is characteristic of an old age, but due to an increase in the tone of vegetative centers, herewith the parasympathetic effects on the myocardium prevailed sympathetic ones.

scholarly journals EXPRESS: Estimating the Effects of Trait Knowledge on Social Perception

2021 ◽  
pp. 174702182110474
Author(s):  
Andrew Wildman ◽  
Richard Ramsey
Keyword(s):  
Information Processing ◽  
Body Size ◽  
Social Information Processing ◽  
Impression Formation ◽  
Functional Integration ◽  
Processing System ◽  
The Body ◽  
Visual Stream ◽  
Initial Stimulus ◽  
Validation Experiment

Research in social cognition has predominantly investigated perceptual and inferential processes separately, however real-world social interactions usually involve integration between person inferences (e.g., generous, selfish) and the perception of physical appearance (e.g., thin, tall). Therefore, in the current work, we investigated the integration of different person-relevant signals, by estimating the extent to which bias in one social information processing system influences another. Following an initial stimulus-validation experiment (Experiment 1, N=55), two further pre-registered experiments (Experiments 2, N=55 & 3; N=123) employed a priming paradigm to measure the effects of extraversion-diagnostic information on subsequent health and body-size judgements of a target body. The results were consistent across both priming experiments and supported our predictions: compared to trait-neutral control statements, extraversion-diagnostic statements increased judgements of health and decreased those of body size. As such, we show that trait-based knowledge does not only influence mappings towards similar types of person judgments, such as health judgments. Rather, even a brief re-configuration of trait-space alters mappings towards non-trait judgments, which are based on body size and shape. The results complement prior neuroimaging findings that showed functional interactions between the body-selective brain regions in the ventral visual stream and the theory of mind network when forming impressions of others. Therefore, we provide a functional signature of how distinct information processing units exchange signals and integrate information in order to form impressions. Overall, the current study underscores the value of behavioural work in complementing neuroscience when investigating the role and properties of functional integration during impression formation. Additionally, it stresses the potential limitations of an over-reliance on studying separate systems in isolation.

scholarly journals Selecting informative biomarkers for early diagnosis of occupational neurological diseases

2021 ◽  
Vol 100 (9) ◽  
pp. 953-958
Author(s):  
Inna V. Lapko
Keyword(s):  
Insulin Resistance ◽  
Carbohydrate Metabolism ◽  
The Body ◽  
Working Environment ◽  
Total Testosterone ◽  
Physical Factors ◽  
Lumbosacral Radiculopathy ◽  
Vibration Disease ◽  
Neurohumoral Regulation ◽  
The Impact

Introduction. At present, the patterns of changes in the levels of biomarkers and the relationship of changes in their values with the pathogenesis of diseases caused by the impact of adverse factors of labour activity are not sufficiently studied. The most unresolved issues are the choice of informative laboratory indicators and diagnostic test systems in investigating the impact of physical factors on the working environment (vibration and physical overload) neurohumoral regulation: pituitary-adrenal pituitary-thyroid, pituitary-gonadal system and hormonal indicators of carbohydrate metabolism. The aim of the study was to determine diagnostic hormonal markers and integral indices to identify early changes in the neurohumoral status in the body of workers under the influence of working environment factors. Materials and methods. 330 workers of mining and machine-building enterprises were examined. Of these, 128 people with vibration disease, 45 people - with lumbosacral radiculopathy, combined pathology (vibration disease and lumbosacral radiculopathy) was detected in 60 persons. The preclinical stage (initial signs of diseases) was noted in 97 workers. Laboratory studies included hormones and integral indices of the pituitary-adrenal, pituitary-thyroid, pituitary-gonadal system, carbohydrate metabolism. To select the diagnostic significance of laboratory biomarkers, diagnostic sensitivity, prenosological value, pathognomonicity, direction, severity, and selectivity of changes in biomarker levels were evaluated. Results. The combined effect of vibration and physical overload on the body of workers was found to have a unidirectional and systemic impact on the levels of hormones of the pituitary-adrenal, pituitary-thyroid and pituitary-gonadal systems, increases insulin resistance. The severity of changes in neurohumoral regulation indicators depends on the nature and severity of the occupational neurological disease. The highest diagnostic sensitivity (Df = 72-74%) in vibration disease and its combination with lumbosacral radiculopathy was obtained for pituitary-gonadal hormones and indicators of insulin resistance. The lowest values of Dh are typical for the hormones of the pituitary-thyroid system (no more than 14%). To identify early changes in neurohumoral regulation in the body under the influence of vibration and physical exertion, it is most informative to determine the concentration of total testosterone, luteinizing hormone and insulin, as well as the integral pituitary-adrenal index, insulin resistance indices. To identify hidden disorders of the pituitary-thyroid system, the definition of the essential thyroid index can be used. Discussion. The results obtained allowed us to assess the nature of changes in the levels of hormones of the pituitary-adrenal, pituitary-thyroid and pituitary-gonadal systems and carbohydrate metabolism and to propose informative laboratory biomarkers reflecting early changes in neurohumoral regulation under the influence of physical factors of the working environment. Conclusions. To identify early changes in neurohumoral regulation in the body of workers under the influence of vibration and physical exertion, the most informative is the determination of the concentration of total testosterone, luteinizing hormone and insulin, the integral pituitary-adrenal index, and insulin resistance indices. To identify hidden disorders of the pituitary-thyroid system, the definition of the integral thyroid index can be used.

scholarly journals The adaptive potential of workers in greenhouse farms in the Voronezh region

2021 ◽  
Author(s):  
L.A. Yatsenko ◽  
N.V. Dzen ◽  
N.V. Gabbasova ◽  
N.P. Mamchik
Keyword(s):  
Environmental Factors ◽  
Chronic Diseases ◽  
Human Body ◽  
The Body ◽  
External Factors ◽  
Adaptive Potential ◽  
Production Factors ◽  
Adaptive Capabilities ◽  
Voronezh Region ◽  
Integral Indicator

Adaptive potential is an indicator of the level of adaptability of the human body to various and changing environmental factors. The adaptive capabilities of the body are influenced not only by external factors, but also by internal - the state of the body as a whole, by the presence or absence of chronic diseases. Therefore, the adaptive potential was used as an integral indicator of a person's adaptability to production factors. The aim of the study was to assess the adaptive capabilities of the organism of workers in greenhouse farms in the Voronezh region. The study was carried out at the enterprises of the closed ground of the region by the method of questioning, the objects of the study were 125 women aged 27-45 years. In most cases, there are violations of the adaptive capabilities of the organism among the studied workers of greenhouse farms, and even a breakdown in adaptation was revealed in 0.8%. In less than half of the cases, the adaptive potential of the greenhouses was within the normal. The adaptive reserves of the greenhouses workers decrease with age.

scholarly journals Social demand of society as a factor of specifying the goals of foreign language teaching in technical university

2020 ◽  
pp. 115-125
Author(s):  
Natalia L. Baydikova
Keyword(s):  
Foreign Language ◽  
Information Technologies ◽  
Research University ◽  
Language Teaching ◽  
Foreign Language Teaching ◽  
Professional Activity ◽  
Federal State ◽  
Social Demand ◽  
Technical University ◽  
State Educational

The structure of the article is determined by the logic of designing the goals of foreign language teaching in a technical university. The highest level of generality of goals reflects the social demand of society as a whole and is presented in the Federal State Educational Standard of Higher Education. At the second level of goal formulation (Model Discipline Programs), they are specified according to the needs of the spheres of economics. In the development of Work Programs of Discipline within the framework of teaching in a specific university, final clarification of goals is required depending on the requirements of regional employers (the third level of specification of goals). In order to clarify the objectives of teaching foreign language to students of technical universities taking into account the requirements of the regional labour market, a questionnaire was conducted in 2019 for graduates of the National Research University „Moscow Institute of Electronic Technology,” working in a specialty in enterprises in the field of exact technologies in Zelenohrad (Moscow). The questionnaire showed that in addition to the four types of speech activities specified in the Model Programs on Foreign Language for Non-Language Universities, engineers use interpretation and translation in their professional activities. The rating of types of foreign language speech activity in descending order of their importance for professional activity of the engineer is as follows: reading – auditing – translation – writing – speaking. The most demanded professional foreign-language tasks in all types of speech activities (except translation) are solved by modern engineers in communicative situations using information technologies.

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