scholarly journals Correlation of duration, hypertension and glycemic control with microvascular complications of diabetes mellitus at a tertiary care hospital

2017 ◽  
Vol 4 (1) ◽  
Author(s):  
amnath Santosh Ramanathan
2020 ◽  
Vol 11 (2) ◽  
pp. 2049-2055
Author(s):  
Raveendra babu K ◽  
Deepika Reddy B ◽  
Bheemamma P ◽  
Vamshi Krishna E ◽  
Chinna Eswaraiah M

The major cause of mortality and morbidity in the present generation is diabetes mellitus. The high prevalence of microvascular complications in diabetes mellitus occurs due to the untreated long duration of hyperglycemia. The main aim of the study is assessing the prevalence of microvascular complications of patients who are diagnosed with diabetes mellitus in public tertiary care hospitals. A retro-prospective observational study was conducted in the outpatient department of medicine at a tertiary care hospital. We took the samples of a total of 300 consecutive patients who are diagnosed with diabetes mellitus with microvascular complications were included in the study. To diagnose microvascular complications of diabetes mellitus clinical parameters, patient past and present history and other related investigations were included. A total of 300 patients in this study, 160 are males and 140 are females. The age range was 30-80 years, with a mean age of 49.43±13.45 years. 31% of patients are diagnosed with neuropathy, 35% of patients are diagnosed with retinopathy and 34% of patients are diagnosed with nephropathy. 68.6% of patients are affected with microalbuminuria, whereas 31.3% of patients are affected with macroalbuminuria. [HbA1C] levels are divided into two groups on the basis of glycated hemoglobin levels in subjects. The patients with HbA1C >7.5% are found to 61% and 39% are found to be in the range of HbA1C 6.5-7.5%. By comparing both patients with HbA1C>7.5% are more prone to microvascular complications than that of HbA1C 6.5-7.5%. The 23% subjects had normal BMI [18.5-24.99kg/m2, 55% subjects were over-weight [25-29.99kg/m2 and 21.3% subjects were obese [>30kg/m2]. Early detection and identification of DM may reduce the risk of getting complications. To prevent or retard further progression of these complications, we should control blood sugar levels.


2016 ◽  
Vol 04 (02) ◽  
pp. 133-136 ◽  
Author(s):  
Amit Thour ◽  
Ramninder Nagra ◽  
Arunjeet Gosal ◽  
Tejasav Sehrawat ◽  
Subhash Das ◽  
...  

Abstract Background: Anxiety has been shown to be associated with poor outcomes in people with diabetes. However, there has been limited data, especially from India, which has specifically examined whether diabetes mellitus is associated with an increased likelihood of comorbid anxiety. Aim: The aim was to estimate the prevalence of anxiety in patients with diabetes and to determine the association of anxiety with age, sex, and other related parameters. Setting: Endocrine clinic, tertiary care hospital. Design: Cross-sectional. Materials and Methods: The study was cross-sectional carried out in endocrinology clinic of tertiary care hospital in North India. Cases were patients with type 2 diabetes mellitus above 30 years of age. Anxiety was assessed using the generalized anxiety disorders 7-item (GADs-7) scale. The relationship with a sociodemographic profile, duration of diabetes, hypertension, and microvascular complications was also analyzed. Results: Seventy-three subjects (42.5% females) with mean age 50.8 ± 9.2 years were evaluated. The prevalence of anxiety was 34%. Severe anxiety (GAD-7 score ≥15) was present in three (4%) subjects, moderate anxiety (GAD-7 score ≥10) was present in six (8%) subjects, and mild anxiety was present in 16 (22%) of subjects. Anxiety increased with fasting plasma glucose, hypertension, was more in women, but the differences were not statistically significant. Conclusions: Our study demonstrates a higher prevalence of anxiety in patients with type 2 diabetes. No factor was significantly associated with anxiety. Therefore, anxiety should be assessed in each and every patient, irrespective of other factors.


Author(s):  
Anand V Nimbal ◽  
Vikas C Desai ◽  
Shardha Bai Rathod

ABSTRACTObjective: Diabetes mellitus is the leading health problem across the world. It is associated with several complications such as retinopathy, neuropathy,oral manifestations, chronic macrovascular and microvascular complications. Our objective is to compare these oral manifestations in controlled anduncontrolled diabetic patients.Methods: A study was conducted on total of 100 diabetic patients. The patients were divided into two groups: Group I (n=50) consists of controlleddiabetic patients and Group II (n=50) consists of uncontrolled diabetic patients. Before, the start of the study proper oral examination was donefor both the groups. Samples were collected and were subjected to microbial examination. Comparison between both the groups was done for oralmanifestations.Results: It showed that uncontrolled diabetic patients had a higher incidence of oral manifestations such as hyposalivation, parotid enlargement,burning sensation of mouth, taste alterations, sialorrhea, dental carries, and microbial lesions than controlled diabetes patients.Conclusion: Uncontrolled diabetic patients had higher risk of oral manifestations than controlled diabetic individuals.Keywords: Diabetes mellitus, Retinopathy, Neuropathy, Oral manifestations, Periodontitis, Hyposalivation.


Author(s):  
Mounica Chappidi ◽  
Shalini Shivananjiah ◽  
Chethana Thirthahalli ◽  
Radhika Kunnavil ◽  
Nandagudi Srinivasa Murthy

Background: Diabetes mellitus (DM), a common metabolic disorder, is associated with complications that can affect the quality of life. The current study was taken to study the frequency of complications among DM patients attending Out Patient Department (OPD) of Endocrinology at a tertiary care hospital and to study the association of select socio-demographic factors and select biochemical parameters among patients with complications.Methods: Case record analysis of 250 out patients with DM (Type 1 and 2) in the month of August 2016 was done. Permission from Hospital Administration and Department of Endocrinology was obtained to access records. Socio-demographic details, anthropometry, blood pressure recordings of the past visit, DM duration, laboratory investigations, complications, treatment & other morbidities were noted.Results: Of the 250 patients, 138 (55.2%) were males. Patients with cardiovascular complications, ocular complications, neuropathy, peripheral arterial diseases, nephropathy and cerebrovascular complications were 21.2%, 19.2%, 16.8%, 12.8%, 11.2% and 6.0% respectively. Poor glycemic control (HbA1c>7.5%) was seen in 51.2% of patients with DM related complications. It was noticed that 78.5% of the patients with chronic complications had DM for more than 5 years duration. Logistic regression analysis showed age (≥60 years), gender (males) and serum creatinine levels (>1.2 mg/dl in males and >0.9 mg/dl in females) to be associated with occurrence of complications in patients with DM.Conclusions: Efforts need to be directed at intense glycemic control, strengthening awareness regarding self care, early screening and appropriate management to prevent and minimize complications.


Author(s):  
PRUDENCE A. RODRIGUES ◽  
DAWN TESLIN DAMIEN ◽  
MARY CECIL K. T. ◽  
NARESH KUMAR M. ◽  
RESHMA S. S. ◽  
...  

Objective: The objective of this study is to evaluate prescribing pattern, analyze drug-related problems, identify co-morbidities and complications in Type 2 Diabetes Mellitus patients and also to perform cost analysis of Biguanides, Sulfonylureas, Dipeptidyl Peptidase Inhibitors Methods: A Prospective observational study was done in General Medicine and Endocrinology Departments of PSG Hospitals. A total of 200 study subjects, including both inpatients and outpatients, above 18 y of age, prescribed with OHAs (Biguanides, Sulfonylureas and DPP4 inhibitors) were included in the study. Results: Diabetes was more prevalent among males. OHAs were most prescribed in the age group of 51-60 y. Hypertension (71%) was the most common comorbidity and Diabetic neuropathy (23%) was the most common complication found in the patients. Multidrug therapy (72.5%) was most prescribed in diabetic patients, followed by Biguanides. Hypoglycemia was the most prevalent ADR. Cost analysis showed that T. Linagliptin was of high cost and T. Glimepiride being the low cost. Using WHO core indicators prescribing patterns were assessed. Feedback was collected and results were reported to the physicians which showed rational utilization of drugs. Conclusion: The study on drug utilization conducted in a tertiary care hospital helped us to find out that prescribing trends seems to be progressing towards combination therapy, predominantly two-drug therapy


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