scholarly journals Study of Ocular Complications of Diabetes Mellitus in Patients Attending in Tertiary Care Hospital at S.K.M.C.H., Muzaffarpur, Bihar

Author(s):  
Dr Ramakant Thakur ◽  
2020 ◽  
Vol 11 (2) ◽  
pp. 2049-2055
Author(s):  
Raveendra babu K ◽  
Deepika Reddy B ◽  
Bheemamma P ◽  
Vamshi Krishna E ◽  
Chinna Eswaraiah M

The major cause of mortality and morbidity in the present generation is diabetes mellitus. The high prevalence of microvascular complications in diabetes mellitus occurs due to the untreated long duration of hyperglycemia. The main aim of the study is assessing the prevalence of microvascular complications of patients who are diagnosed with diabetes mellitus in public tertiary care hospitals. A retro-prospective observational study was conducted in the outpatient department of medicine at a tertiary care hospital. We took the samples of a total of 300 consecutive patients who are diagnosed with diabetes mellitus with microvascular complications were included in the study. To diagnose microvascular complications of diabetes mellitus clinical parameters, patient past and present history and other related investigations were included. A total of 300 patients in this study, 160 are males and 140 are females. The age range was 30-80 years, with a mean age of 49.43±13.45 years. 31% of patients are diagnosed with neuropathy, 35% of patients are diagnosed with retinopathy and 34% of patients are diagnosed with nephropathy. 68.6% of patients are affected with microalbuminuria, whereas 31.3% of patients are affected with macroalbuminuria. [HbA1C] levels are divided into two groups on the basis of glycated hemoglobin levels in subjects. The patients with HbA1C >7.5% are found to 61% and 39% are found to be in the range of HbA1C 6.5-7.5%. By comparing both patients with HbA1C>7.5% are more prone to microvascular complications than that of HbA1C 6.5-7.5%. The 23% subjects had normal BMI [18.5-24.99kg/m2, 55% subjects were over-weight [25-29.99kg/m2 and 21.3% subjects were obese [>30kg/m2]. Early detection and identification of DM may reduce the risk of getting complications. To prevent or retard further progression of these complications, we should control blood sugar levels.


Author(s):  
PRUDENCE A. RODRIGUES ◽  
DAWN TESLIN DAMIEN ◽  
MARY CECIL K. T. ◽  
NARESH KUMAR M. ◽  
RESHMA S. S. ◽  
...  

Objective: The objective of this study is to evaluate prescribing pattern, analyze drug-related problems, identify co-morbidities and complications in Type 2 Diabetes Mellitus patients and also to perform cost analysis of Biguanides, Sulfonylureas, Dipeptidyl Peptidase Inhibitors Methods: A Prospective observational study was done in General Medicine and Endocrinology Departments of PSG Hospitals. A total of 200 study subjects, including both inpatients and outpatients, above 18 y of age, prescribed with OHAs (Biguanides, Sulfonylureas and DPP4 inhibitors) were included in the study. Results: Diabetes was more prevalent among males. OHAs were most prescribed in the age group of 51-60 y. Hypertension (71%) was the most common comorbidity and Diabetic neuropathy (23%) was the most common complication found in the patients. Multidrug therapy (72.5%) was most prescribed in diabetic patients, followed by Biguanides. Hypoglycemia was the most prevalent ADR. Cost analysis showed that T. Linagliptin was of high cost and T. Glimepiride being the low cost. Using WHO core indicators prescribing patterns were assessed. Feedback was collected and results were reported to the physicians which showed rational utilization of drugs. Conclusion: The study on drug utilization conducted in a tertiary care hospital helped us to find out that prescribing trends seems to be progressing towards combination therapy, predominantly two-drug therapy


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