scholarly journals What is the effect of peripheral muscle fatigue, pulmonary function, and body composition on functional exercise capacity in acromegalic patients?

2015 ◽  
Vol 27 (3) ◽  
pp. 719-724 ◽  
Author(s):  
Agnaldo José Lopes ◽  
Débora Pedroza Guedes da Silva ◽  
Arthur de Sá Ferreira ◽  
Leandro Kasuki ◽  
Mônica Roberto Gadelha ◽  
...  
Keyword(s):  
Body Composition ◽  
Pulmonary Function ◽  
Muscle Fatigue ◽  
Exercise Capacity ◽  
Peripheral Muscle ◽  
Functional Exercise ◽  
Functional Exercise Capacity

scholarly journals Relaxation and Exercise in Lymphoma Survivors (REIL Study): A Randomised Clinical Trial Protocol

2018 ◽  
Vol 4 (Supplement 2) ◽  
pp. 120s-120s
Author(s):  
S. Hathiramani ◽  
R. Pettengell ◽  
H. Moir ◽  
A. Younis
Keyword(s):  
Body Composition ◽  
Pulmonary Function ◽  
Cancer Survivors ◽  
Exercise Capacity ◽  
Well Being ◽  
Psychological Status ◽  
Care Pathways ◽  
Functional Exercise ◽  
Functional Exercise Capacity ◽  
Lymphoma Survivors

Background: Cancer survivors commonly report ongoing physical and psychological needs and adverse effects due to disease and treatment exposures including fatigue, pain, depression and decreased quality of life (QoL). Both relaxation and exercise interventions have demonstrated a positive effect on these symptoms. However these benefits have been relative to a control group, and there has been a call for further intervention studies in survivors to move beyond wait-list control groups and to compare with active control or other empirically supported interventions, such as comparison of relaxation to exercise intervention, to determine which is more beneficial. Aim: This paper presents the REIL (Relaxation and Exercise In Lymphoma) study protocol using recommended SPIRIT 2013 guidelines. The primary aim of the REIL Study is to compare the effect of two interventions - exercise and relaxation on QoL in a sample of lymphoma patients in remission postchemotherapy. Secondary aims are to investigate the effects of the two interventions on body composition, cardiovascular status, pulmonary function, muscle strength, functional exercise capacity, well-being and psychological status; and explore perceptions about participation in the posttreatment intervention program. Methods: Eligible participants (n=36) will be randomized to an exercise or relaxation home-based program to perform at least three times per week. The primary outcome measure is QoL, assessed by the European Organization for Research and Treatment of Cancer QoL Questionnaire Core 30 (EORTC QLQ-C30). Secondary outcome measures include body composition, cardiovascular status, pulmonary function, strength, functional exercise capacity, well-being and psychological status. Total duration of the study will be 12 weeks and outcome measures will be assessed at baseline, 6 weeks and at the end of the study. Results: Results from this study will inform development of effective care pathways for the increasing population of cancer survivors in general, and lymphoma in particular. It is anticipated that preliminary results from this study will be available by October 2018. Conclusion: Although it is well documented that cancer survivors commonly suffer from consequences of treatment which have a negative impact on their QoL, there are currently no recommended care pathways following completion of primary medical treatment. Evidence suggests that both relaxation and exercise can significantly improve ongoing symptoms in cancer survivors, but there is no consensus on which intervention is more effective. Results from the REIL study will aid in the development of evidence-based survivorship care pathways for cancer and lymphoma survivors, potentially prevent long-term complications, and help in a smooth transition from being a cancer patient to a fully-functioning member of society. This may lead to reduced use of healthcare resources by this population.

scholarly journals Comparison of functional exercise capacity, quality of life and respiratory and peripheral muscle strength between patients with stable angina and healthy controls

2020 ◽  
Vol 48 (12) ◽  
pp. 030006052097921
Author(s):  
Irem Huzmeli ◽  
Aysel-Yildiz Ozer ◽  
Oguz Akkus ◽  
Nihan Katayıfcı ◽  
Fatih Sen ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Muscle Strength ◽  
Pulmonary Function ◽  
Exercise Capacity ◽  
Stable Angina ◽  
Healthy Controls ◽  
Peripheral Muscle ◽  
Functional Exercise ◽  
Functional Exercise Capacity

Objective We aimed to compare functional exercise capacity, respiratory and peripheral muscle strength, pulmonary function and quality of life between patients with stable angina and healthy controls. Methods We compared 33 patients with stable angina (55.21 ± 6.12 years old, Canada Class II–III, left ventricular ejection fraction: 61.92 ± 7.55) and 30 healthy controls (52.70 ± 4.22 years old). Functional capacity (6-minute walk test (6-MWT)), respiratory muscle strength (mouth pressure device), peripheral muscle strength (dynamometer), pulmonary function (spirometer) and quality of life (Short Form 36 (SF-36)) were evaluated. Results 6-MWT distance (499.20 ± 51.91 m versus 633.05 ± 57.62 m), maximal inspiratory pressure (85.42 ± 20.52 cmH2O versus 110.44 ± 32.95 cmH2O), maximal expiratory pressure (83.33 ± 19.05 cmH2O versus 147.96 ± 54.80 cmH2O) and peripheral muscle strength, pulmonary function and SF-36 sub-scores were lower in the angina group versus the healthy controls, respectively. Conclusion Impaired peripheral and respiratory muscle strength, reduction in exercise capacity and quality of life are obvious in patients with stable angina. Therefore, these parameters should be considered in stable angina physiotherapy programmes to improve impairments.

Evolution of muscle strength and physical activity 1 year after heart transplantation: a prospective observational study

2021 ◽  
Vol 28 (Supplement_1) ◽  
Author(s):  
M Hornikx ◽  
L Van Aelst ◽  
W Droogne ◽  
S Janssens ◽  
J Van Cleemput
Keyword(s):  
Physical Activity ◽  
Muscle Strength ◽  
Heart Transplantation ◽  
Cardiac Rehabilitation ◽  
Exercise Capacity ◽  
Muscle Weakness ◽  
Peripheral Muscle ◽  
Functional Exercise ◽  
Functional Exercise Capacity

Abstract Funding Acknowledgements Type of funding sources: None. Background Heart transplantation (HTX) is a therapeutic option in a selected group of patients with end-stage heart failure. Although cardiac function normalizes after surgery, maximal exercise capacity of HTX-patients after 1 year is only half that of age- and gender matched healthy subjects. Data on the evolution of muscle strength and physical activity after HTX are scant. Having this knowledge might help to optimize rehabilitation programs. Purpose To describe changes in muscle strength and physical activity following HTX. Methods 58 HTX-patients were addressed, of whom 52 (90%) patients participated in the study. Study visits were planned every 3 months from hospital discharge until 1 year of follow-up. 43 HTX-patients (67% male; age: 48 ± 14 years; BMI: 24 ± 4 kg/m²) fulfilled the study protocol. Outcome measures included functional exercise capacity (6MWD), peripheral strength (QF), respiratory muscle strength (MIP) and objectively measured physical activity (PAwalk, walking intensity (WI), PAsteps). All patients received physiotherapy at home during the first 6 weeks, as standard of care after thoracic surgery. After that, cardiac rehabilitation in a specialized center was started. Data were analyzed using repeated measures ANOVA, with Bonferroni test as post-hoc test. Results 6MWD (+178 ± 17 meter), QF (+26 ± 4 Nm) and MIP (-32 ± 3 cmH2O) significantly improved over time (p < 0.0001). Despite improvements in QF, peripheral muscle weakness was still present in 32% of patients 1 year post-HTX. A significant time effect in PA (PAwalk (+33 ± 7 minutes/day), WI (+0.036 ± 0.007 g) and PAsteps (+3711 ± 640 steps/day)) could be noticed (p < 0.0001). Sedentary time did not significantly change during follow-up (p = 0.14). (Figure 1) Conclusion Functional exercise capacity and muscle strength gradually improve during 1 year after HTX. A considerable number of patients still present with peripheral muscle weakness. Despite improvements in PA, results remain below recommended health levels. Enrollment in a cardiac rehabilitation program, offering a combined exercise and PA intervention seems warranted to further enhance health outcomes in this patient population. Abstract Figure 1

scholarly journals Exercise capacity and pulmonary function in individuals with leprosy

2014 ◽  
Vol 27 (1) ◽  
pp. 29-38
Author(s):  
Marcelo Taglietti ◽  
Celeide Pinto Aguiar Peres
Keyword(s):  
Muscle Strength ◽  
Pulmonary Function ◽  
Exercise Capacity ◽  
Physical Disability ◽  
Pulmonary Function Tests ◽  
Walking Distance ◽  
Functional Exercise ◽  
Leprosy Patients ◽  
Functional Exercise Capacity ◽  
The Impact

Introduction In Brazil 23% of leprosy patients have some type of physical disability after discharge. The impact on the respiratory system and correlation with functional exercise capacity is still unknown. Objective To correlate the functional exercise capacity and pulmonary function in individuals with leprosy sequelae. Materials and methods We evaluated 20 subjects and 25 controls by sensory evaluation, muscle strength, graduate the grade of physical disability followed by pulmonary function tests with spirometry and manovacuometry, besides the functional exercise capacity through the six minute walking distance (6MWD). Results The majority (75%) of the subjects showed physical disability grade 1. The mean of the maximal inspiratory pressure were below than normal -71 ± 31 cmH20 and maximal expiratory pressure +89 ± 22 cmH20. Spirometric values presented measures within normal value. The functional exercise capacity found a reduced value with a distance of 404 ± 92m. Positive and statistically significant correlation between the inspiratory pressures with 6MWD (r = 0.49, p = 0.025) and, similarly, expiratory pressure (r = 0.53, p = 0.004). The same evidence is found in maximal respiratory pressures of individuals in grade 1 with significant correlations (r = 0.52, p = 0.036) and (r = 0.51, p = 0.042). Conclusion Individuals with leprosy sequelae had impaired respiratory muscle strength and functional exercise capacity. Maximal respiratory pressures are presented as an independent factor in the change in performance in the functional exercise capacity.

scholarly journals THU0608-HPR VALIDITY OF SIX MINUTE STEPPER TEST IN EVALUATION OF FUNCTIONAL EXERCISE CAPACITY IN PATIENTS WITH ANKYLOSING SPONDYLITIS

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 545.1-546
Author(s):  
S. Bayram ◽  
N. G. Tore ◽  
F. Sarİ ◽  
D. C. Saraç ◽  
G. Gülsün ◽  
...  
Keyword(s):  
Ankylosing Spondylitis ◽  
Exercise Capacity ◽  
Muscle Performance ◽  
Walking Distance ◽  
Walk Test ◽  
Six Minute Walk Test ◽  
Peripheral Muscle ◽  
Functional Exercise ◽  
Functional Exercise Capacity ◽  
Minute Walk

Background:In most patients with ankylosing spondylitis (AS), exercise capacity decreases due to pulmonary dysfunction, chest wall restriction and peripheral muscle weakness. The six-minute walk test (6MWT) is a validated simple field, hence frequently used to evaluate exercise capacity. However, 6MWT has some limitations, especially the fact that it requires a corridor of at least 30 meters long to perform this test which can limit its use in some centers. Shorter corridors force patients to turn more frequently, slowing down the pace of walking that reduces potential walking distance. To overcome technical and spatial limitations, 6-minute stepper test (6MST) has been proposed to evaluate exercise capacity. In the literature 6MST has been suggested for a variety of diseases. Since, it requires only a limited amount of space and equipment and is feasible, easy to perform, well tolerated.Objectives:In the literature, there is no study in which 6MST is used to evaluate exercise capacities of patients with AS. Therefore, the aim of this study was to evaluate validity of 6MST in AS population in comparison to 6MWT.Methods:6MWT and 6MST were performed in 51 patients with AS (52.26±13.33 years, 30F/21M). Demographic and clinical characteristics were recorded. Functional exercise capacity was evaluated using 6MWT and 6MST. The total distance of 6MWT was compared to the total number of steps of 6MST. Before, during and after 6MWT and 6MST, heart rate (HR), oxygen saturation (SpO2), breathing frequency (BF), blood pressure (BP), dyspnea and fatigue were assessed using modified Borg scale.Results:The number of steps on the 6MST was significantly correlated with the distance of the 6MWT (r=0.61, p<0.0001). Dyspnea (p=0.04) and leg fatigue (p<0.0001) was significantly higher in 6MST than in 6MWT. HR, SpO2, BF, BP and fatigue were similar in both 6MST and 6MWT.Conclusion:The 6MST is a valid test to evaluate exercise capacity in patients with AS. It is also an appropriate alternative to the 6MWT for determining exercise capacity when the 6MWT is not feasible due to technical restrictions. The 6MST can be proposed as a new exercise capacity evaluation tool in AS, as it is valid, reliable, portable and inexpensive.References:[1]van der Esch, Martin, et al. Respiratory muscle performance as a possible determinant of exercise capacity in patients with ankylosing spondylitis. Australian Journal of Physiotherapy, 2004;50(1):41-46.[2]ATS Committee on Proficiency Standards for Clinical Pulmonary Function Laboratories. ATS statement: guidelines for the six-minute walk test. Am J Respir Crit Care Med. 2002;166(1):111–117.[3]Grosbois JM, Riquier C, Chehere B, et al. Six-minute stepper test: a valid clinical exercise tolerance test for COPD patients. Int J Chron Obstruct Pulmon Dis. 2016;11:657–663.Disclosure of Interests:None declared

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