scholarly journals THU0608-HPR VALIDITY OF SIX MINUTE STEPPER TEST IN EVALUATION OF FUNCTIONAL EXERCISE CAPACITY IN PATIENTS WITH ANKYLOSING SPONDYLITIS

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 545.1-546
Author(s):  
S. Bayram ◽  
N. G. Tore ◽  
F. Sarİ ◽  
D. C. Saraç ◽  
G. Gülsün ◽  
...  

Background:In most patients with ankylosing spondylitis (AS), exercise capacity decreases due to pulmonary dysfunction, chest wall restriction and peripheral muscle weakness. The six-minute walk test (6MWT) is a validated simple field, hence frequently used to evaluate exercise capacity. However, 6MWT has some limitations, especially the fact that it requires a corridor of at least 30 meters long to perform this test which can limit its use in some centers. Shorter corridors force patients to turn more frequently, slowing down the pace of walking that reduces potential walking distance. To overcome technical and spatial limitations, 6-minute stepper test (6MST) has been proposed to evaluate exercise capacity. In the literature 6MST has been suggested for a variety of diseases. Since, it requires only a limited amount of space and equipment and is feasible, easy to perform, well tolerated.Objectives:In the literature, there is no study in which 6MST is used to evaluate exercise capacities of patients with AS. Therefore, the aim of this study was to evaluate validity of 6MST in AS population in comparison to 6MWT.Methods:6MWT and 6MST were performed in 51 patients with AS (52.26±13.33 years, 30F/21M). Demographic and clinical characteristics were recorded. Functional exercise capacity was evaluated using 6MWT and 6MST. The total distance of 6MWT was compared to the total number of steps of 6MST. Before, during and after 6MWT and 6MST, heart rate (HR), oxygen saturation (SpO2), breathing frequency (BF), blood pressure (BP), dyspnea and fatigue were assessed using modified Borg scale.Results:The number of steps on the 6MST was significantly correlated with the distance of the 6MWT (r=0.61, p<0.0001). Dyspnea (p=0.04) and leg fatigue (p<0.0001) was significantly higher in 6MST than in 6MWT. HR, SpO2, BF, BP and fatigue were similar in both 6MST and 6MWT.Conclusion:The 6MST is a valid test to evaluate exercise capacity in patients with AS. It is also an appropriate alternative to the 6MWT for determining exercise capacity when the 6MWT is not feasible due to technical restrictions. The 6MST can be proposed as a new exercise capacity evaluation tool in AS, as it is valid, reliable, portable and inexpensive.References:[1]van der Esch, Martin, et al. Respiratory muscle performance as a possible determinant of exercise capacity in patients with ankylosing spondylitis. Australian Journal of Physiotherapy, 2004;50(1):41-46.[2]ATS Committee on Proficiency Standards for Clinical Pulmonary Function Laboratories. ATS statement: guidelines for the six-minute walk test. Am J Respir Crit Care Med. 2002;166(1):111–117.[3]Grosbois JM, Riquier C, Chehere B, et al. Six-minute stepper test: a valid clinical exercise tolerance test for COPD patients. Int J Chron Obstruct Pulmon Dis. 2016;11:657–663.Disclosure of Interests:None declared

Author(s):  
Lisa Lancaster

The six-minute walk test (6MWT) is a simple test that is widely used to assess functional exercise capacity in patients with idiopathic pulmonary fibrosis (IPF). Patients with IPF have reduced exercise capacity due to a number of factors, such as impaired respiratory mechanics and circulatory problems. As a self-paced and usually submaximal exercise test, the 6MWT reflects the exercise level of everyday activities. Variables measured during the 6MWT, such as six-minute walk distance (6MWD) and desaturation, are strong predictors of mortality in patients with IPF. However, the results of a 6MWT are affected by numerous factors, including age, body size, comorbidities and the use of supplemental oxygen during the test, and these need to be borne in mind when interpreting the results of individual and serial tests. Clinical studies, including trials of potential therapies for IPF, have differed in the methodology used to implement the 6MWT, hindering the comparison of results across studies. In this review, I describe the utility of the 6MWT in patients with IPF and provide recommendations for standardisation of the test for use both in clinical practice and research. A brief video


2018 ◽  
Vol 3 ◽  
pp. 40-40
Author(s):  
Peter Odion Ubuane ◽  
Barakat Adeola Animasahun ◽  
Olufunke Adewumi Ajiboye ◽  
Mogbafolu Olugbemiga Kayode-Awe ◽  
Omotola Aderiyike Ajayi ◽  
...  

Respiration ◽  
2021 ◽  
pp. 1-6
Author(s):  
Isabell Anna Just ◽  
Felix Schoenrath ◽  
Philipp Passinger ◽  
Julia Stein ◽  
Dagmar Kemper ◽  
...  

<b><i>Background and Objectives:</i></b> The 6-minute walk test (6MWT), as a clinical assessment tool for functional exercise capacity, is an integral component of lung allocation scores (LASs). In times of the coronavirus disease (COVID-19) pandemic, patients underwent 6MWTs wearing a surgical mask in ambulatory care. We investigated the impact of wearing a mask on 6-minute walk distances (6MWDs). <b><i>Method:</i></b> 6MWDs of 64 patients with end-stage lung diseases wearing an oronasal surgical mask were retrospectively compared to previously investigated 6MWDs of the same cohort, in a pre-COVID-19 pandemic era, without wearing a mask. Four patients were excluded due to a primary vascular disease, 29 patients due to clinically unstable pulmonary functions, and 1 patient due to a psychiatric disorder. <b><i>Results:</i></b> The median age of the patients included was 55 (46–58) years; 15 (48%) were male. Ten (32.2%) were on the Eurotransplant lung transplant waiting list with a median LAS of 34.3 (31.9–36.2). Twenty (64.5%) patients had chronic obstructive pulmonary diseases, 7 (22.6%) had interstitial lung diseases, and 4 (12.9%) had other end-stage lung diseases. The mean 6MWD without versus with wearing a mask was 306.9 (101.9) versus 305.7 (103.8) m, with a mean difference of −1.19 m (95% confidence interval −13.4 to 11.03). The observed difference is statistically equivalent to zero (<i>p</i> &#x3c; 0.001). No significant differences in 6MWDs were observed between the clinical groups. <b><i>Conclusion:</i></b> Wearing an oronasal surgical mask did not affect the 6MWDs of patients with advanced lung diseases. Therefore, a masked 6MWT appears to provide a reliable examination of functional exercise capacity in this cohort.


2015 ◽  
Vol 95 (5) ◽  
pp. 720-729 ◽  
Author(s):  
Edwin J. van Adrichem ◽  
Gerda D. Reinsma ◽  
Sanne van den Berg ◽  
Wim van der Bij ◽  
Michiel E. Erasmus ◽  
...  

BackgroundExercise capacity, muscle function, and physical activity levels remain reduced in recipients of lung transplantation. Factors associated with this deficiency in functional exercise capacity have not been studied longitudinally.ObjectiveThe study aims were to analyze the longitudinal change in 6-minute walking distance and to identify factors contributing to this change.DesignThis was a longitudinal historical cohort study.MethodsData from patients who received a lung transplantation between March 2003 and March 2013 were analyzed for the change in 6-minute walking distance and contributing factors at screening, discharge, and 6 and 12 months after transplantation. Linear mixed-model and logistic regression analyses were performed with data on characteristics of patients, diagnosis, waiting list time, length of hospital stay, rejection, lung function, and peripheral muscle strength.ResultsData from 108 recipients were included. Factors predicting 6-minute walking distance were measurement moment, diagnosis, sex, quadriceps muscle and grip strength, forced expiratory volume in 1 second (percentage of predicted), and length of hospital stay. After transplantation, 6-minute walking distance increased considerably. This initial increase was not continued between 6 and 12 months. At 12 months after lung transplantation, 58.3% of recipients did not reach the cutoff point of 82% of the predicted 6-minute walking distance. Logistic regression demonstrated that discharge values for forced expiratory volume in 1 second and quadriceps or grip strength were predictive for reaching this criterion.LimitationsStudy limitations included lack of knowledge on the course of disease during the waiting list period, type and frequency of physical therapy after transplantation, and number of missing data points.ConclusionsPeripheral muscle strength predicted 6-minute walking distance; this finding suggests that quadriceps strength training should be included in physical training to increase functional exercise capacity. Attention should be paid to further increasing 6-minute walking distance between 6 and 12 months after transplantation.


Circulation ◽  
2012 ◽  
Vol 125 (suppl_10) ◽  
Author(s):  
Alexis L Beatty ◽  
Nelson B Schiller ◽  
Mary A Whooley

Background: The six-minute walk test (6MWT) is commonly used to assess functional exercise capacity in patients with heart or lung disease. However, its ability to predict events in patients with stable ischemic heart disease (IHD) is unknown. Methods: We measured 6MWT distance and treadmill exercise capacity in 556 outpatients with stable IHD between September 2000 and December 2002. Participants were followed for an average of 7.7 years to determine cardiovascular (CV) events (myocardial infarction, heart failure, or death). We used Cox proportional hazards models to evaluate 6MWT distance and treadmill exercise capacity as predictors of subsequent events. Results: Among the 556 patients, there were 82 heart failure hospitalizations, 63 myocardial infarctions, and 184 deaths from any cause. Patients in the lowest quartile of 6MWT distance (284-1375 ft) were 3 times as likely as patients in the highest quartile (1786-2746 ft) to experience CV events (62% vs. 22%, age-adjusted HR 3.15, 95%CI 1.98-5.03, p<0.0001). Each standard deviation (SD) decrease in 6MWT distance (342 ft) was associated with an 86% greater risk of heart failure (age-adjusted HR 1.86, 95%CI 1.51-2.31, p<0.0001), a 47% greater risk of myocardial infarction (age-adjusted HR 1.47, 95%CI 1.15-1.89, p=0.002), a 54% greater risk of death (age-adjusted HR 1.54, 95%CI 1.32-1.80, p<0.0001), and a 55% greater risk of any event (age-adjusted HR 1.55, 95%CI 1.35-1.78, p<0.0001). After adjustment for traditional risk factors and measures of cardiac disease severity (left ventricular ejection fraction, inducible ischemia, diastolic dysfunction, NT-proBNP and CRP), each SD decrease in 6MWT remained associated with a 38% greater risk of CV events (HR 1.38, 95%CI 1.10-1.74, p=0.005). 6MWT distance was similar to treadmill exercise capacity for predicting CV events (age-adjusted c-statistics 0.72 vs. 0.71, p=0.73 for comparison). Conclusions: Distance walked on 6MWT is as good as treadmill exercise capacity for predicting CV events in patients with stable IHD.


2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Elżbieta Domka-Jopek ◽  
Andrzej Jopek ◽  
Agnieszka Bejer ◽  
Ewa Lenart-Domka ◽  
Grzegorz Walawski

Introduction. The Six-Minute Walk Test (6MWT) is a widely used test to measure the physical performance of patients to assess the effectiveness of treatment, to qualify for rehabilitation, and to evaluate its effects..Aim.This paper focuses on the assessment of the growth of a double product (DP) during the 6MWT and its diagnostic value in the assessment of patients with heart failure.Material and Methods. The paper has retrospective character. We analyzed medical records of 412 patients hospitalized for cardiac reasons, in whom a 6MWT was performed. The patients were divided into two groups: one with diagnosed heart failure and a control group.Results. The patients with diagnosed heart failure, compared to the control group, were characterized by a shorter walking distance and greater DP increase at equal walking intervals. After distinguishing the group with the preserved and decreased left ventricle ejection fraction, the value of the DP increase was still higher compared to the control group. The mean DP increase corresponding to one meter of walk was the only one that correlated negatively with the left ventricular ejection fraction.Conclusion.The assessment of the increase of the DP during the march test seems to be a better parameter reflecting the efficiency of the myocardium from the distance of the march.


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