scholarly journals Chemical constituents of Aspergillus sp EJC08 isolated as endophyte from Bauhinia guianensis and their antimicrobial activity

2013 ◽  
Vol 85 (4) ◽  
pp. 1247-1253 ◽  
Author(s):  
Eduardo A.A. Pinheiro ◽  
Josiwander M. Carvalho ◽  
Diellem C.P. dos Santos ◽  
Andre O. Feitosa ◽  
Patricia S.B. Marinho ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Antimicrobial Activity ◽  
Chemical Constituents ◽  
2D Nmr ◽  
Good Activity ◽  
Ergosterol Peroxide ◽  
Aspergillus Sp ◽  
And Staphylococcus Aureus

The present work reports the isolation of five compounds from Aspergillus sp EJC08 isolated as endophytic from Bauhinia guianensis, a tipical plant of the Amazon. The compounds ergosterol (1), ergosterol peroxide (2), mevalolactone (3), monomethylsulochrin (4) and trypacidin A (5) were isolated by chromatographic procedures and identified by spectral methods of 1D and 2D NMR and MS. Compounds 3, 4 and 5 were tested against Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis and Staphylococcus aureus and showed good activity.

Two Epimeric Flavalignans from Trichilia catigua (Meliaceae) with Antimicrobial Activity

2002 ◽  
Vol 57 (5-6) ◽  
pp. 483-488 ◽  
Author(s):  
Moacir G. Pizzolatti ◽  
Andreia F. Venson ◽  
Artur Smânia Júnior ◽  
Elza de F. A. Smânia ◽  
Raimundo Braz-Filho
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Antimicrobial Activity ◽  
Antibacterial Activity ◽  
Natural Products ◽  
Bacillus Cereus ◽  
Spectroscopic Data ◽  
2D Nmr ◽  
And Staphylococcus Aureus

A mixture of flavalignan cinchonains Ia and Ib was isolated from the bark of Trichilia catigua. The structures were established on the basis of spectroscopic data of the natural products and their methylated derivatives including 2D NMR experiments, and compared with data in the literature. These flavalignans exhibited antibacterial activity against Bacillus cereus, Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus.

scholarly journals Synthesis, characterization and antimicrobial activity of novel benzofuran- and thiophene-containing diketoxime derivatives

2017 ◽  
Vol 82 (4) ◽  
pp. 367-377 ◽  
Author(s):  
Demet Coskun ◽  
Seher Gur ◽  
Mehmet Coskun
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Antimicrobial Activity ◽  
Salmonella Enterica ◽  
Good Activity ◽  
E Coli ◽  
Minimum Inhibitory Concentrations ◽  
Serovar Typhimurium ◽  
And Staphylococcus Aureus

The aim of this study was the preparation of 1,1?-(2,5-thiophenediyl) bis[1-(2-benzofuranyl)methanone] (2), the corresponding diketoxime (3), and the ether and ester derivatives (4a?e) of the diketoxime. These compounds were prepared in good yields. Minimum inhibitory concentrations (MIC) of the synthesized compounds 1?4 were determined against Salmonella enterica subsp. enterica serovar Typhimurium, Escherichia coli and Staphylococcus aureus. Among the synthesized compounds, 1 and 4e showed good activity against E. coli, S. enterica and S. aureus.

Synthesis, Characterization and Antimicrobial Activity of Bis-Acetylferrocene Schiff Base

2011 ◽  
Vol 396-398 ◽  
pp. 1875-1878 ◽  
Author(s):  
Yu Ting Liu ◽  
Hai Long Guo ◽  
Da Wei Yin
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Antimicrobial Activity ◽  
Bacillus Subtilis ◽  
Salmonella Typhi ◽  
Bacterial Strains ◽  
Gram Negative ◽  
And Staphylococcus Aureus

Three bis-acetylferrocene schiff bases have been synthesized and characterized by IR, 1H NMR, and elemental analysis, the results conformed well with expected structures. The synthesized compounds were screened in vitro for their antimicrobial activity against three Gram-negative (Escherichia coli, Pseudomonas aeruginosa, and Salmonella typhi) and two Gram-positive (Bacillus subtilis and Staphylococcus aureus) bacterial strains. The results showed that these compounds are show excellent antimicrobia activities against Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi ,Bacillus subtilis,Staphylococcus aureus.

scholarly journals Chemical Constituents and Antimicrobial Activities of Canthium horridum

2010 ◽  
Vol 5 (6) ◽  
pp. 1934578X1000500 ◽  
Author(s):  
Biao Yang ◽  
Guangying Chen ◽  
Xiaoping Song ◽  
Zhong Chen ◽  
Xinming Song ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Bacillus Subtilis ◽  
Aspergillus Niger ◽  
Chemical Constituents ◽  
Antimicrobial Activities ◽  
Syringic Acid ◽  
Good Activity ◽  
First Time ◽  
And Staphylococcus Aureus

Bioassay-guided isolation studies of the extract of Canthium horridum Bl. stem led to the isolation of ten compounds: (+)-syringaresinol (1), scoparone (2), scopoletin (3), 3′-methoxy-4′-hydroxy- trans-cinnamaldehyde (4), sinapic aldehyde (5), syringic acid (6), mannitol (7), vanillic acid 4- O-β-D-glucopyranoside (8), β-daucosterol (9), and β-sitosterol (10). Compounds 1-10 were reported for the first time from this species, and compounds 1, 4, 5, 6, and 8 from the genus. The antimicrobial activities of the isolated compounds were studied; 6 had the highest activity against Bacillus subtilis, but 1 showed good activity against Escherichia coli, Bacillus subtilis and Staphylococcus aureus. Compounds 2, 4 and 6 also inhibited the growth of these three bacteria. None of the compounds demonstrated inhibitory activity against Aspergillus niger.

scholarly journals Chemical Constituents of Sinningia hatschbachii

2017 ◽  
Vol 12 (11) ◽  
pp. 1934578X1701201 ◽  
Author(s):  
Magali S. Amorim ◽  
Alessandra F. Serain ◽  
Marcos José Salvador ◽  
Maria Élida A. Stefanello
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Antimicrobial Activity ◽  
Candida Albicans ◽  
Chemical Constituents ◽  
Spectroscopic Techniques

A new naphthoquinone, 6-hydroxy-7-methoxy-2- O-methylduniol (1), was isolated from the tubers of Sinningia hatschbachii Chautems (Gesneriaceae), together with 10 known compounds: 7-hydroxy-α-dunnione, 7-hydroxy-6-methoxy-α-dunnione, 2,4,4’,6-tetramethoxydihydrochalcone, 4’-hydroxy-2,4,6-trimethoxydihydrochalcone, 4’,2-dihydroxy-4,6-dimethoxydihydrochalcone, methyl 1-hydroxy-4-methoxy-2-naphthoate, methyl 1,4-dimethoxy-2-naphthoate, methyl 4-hydroxybenzoate, calceolarioside B, and conandroside. All compounds were identified by spectroscopic techniques, and comparison with literature. Extracts in hexane, CH2Cl2, EtOAc and EtOH were evaluated for antimicrobial activity against Staphylococcus aureus, S. epidermidis, Escherichia coli, Pseudomonas aeruginosa, Candida albicans, C. dubliniensis, C. glabrata, and C. parapsilosis. All extracts were inactive.

Antimicrobial Activity of 2,5-Dihydroxy-3-methyl-1,4-benzoquinone from Embelia schimperi

2008 ◽  
Vol 63 (1-2) ◽  
pp. 47-50 ◽  
Author(s):  
Ooko Selline Awino ◽  
Paul Chepkwony Kiprono ◽  
Kipkemboi Pius Keronei ◽  
Festus Kaberia ◽  
Andrew Ambogo Obala
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Antimicrobial Activity ◽  
Klebsiella Pneumoniae ◽  
Crude Extract ◽  
Pure Compound ◽  
Salmonella Spp ◽  
Zones Of Inhibition ◽  
And Staphylococcus Aureus

Chromatographic separation of an ethyl acetate extract from Embelia schimperi led to the isolation of a new compound identified as 2,5-dihydroxy-3-methyl-1,4-benzoquinone (1) on the basis of spectroscopic and physical data. The plant’s crude extract and pure compound 1 were assayed for in vitro antimicrobial activity against clinical strains of Salmonella spp., Proteus spp., Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli, Cryptococcus neoformans, Shigella dysentriae and Staphylococcus aureus. Disc diffusion method was used and zones of inhibition, after respective incubation periods, were used to quantify antimicrobial activity. Standard antibiotics namely: augmentin, cotrimoxazole, gentamycin, tetracycline and lyncomycin were used as controls. The crude extract was inactive while the pure compound 1 showed significant activities against Salmonella spp., Proteus spp., Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli, Cryptococcus neoformans, Shigella dysentriae and Staphylococcus aureus with zones of inhibition ranging from 10−20 mm. The most sensitive microorganism was P. aeruginosa while C. neoformans was insensitive to both the crude extract and compound 1.

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