In(compatibility) of intravenous drugs in critical units: adult cohort

ABSTRACT Objectives: To analyze potential (in)compatibilities of intravenous drugs based on the scheduling prepared by the nursing team. Methods: historic cohort (retrospective) with 110 adults in critical units. Intravenous medications were identified concomitantly, whose pairs were analyzed for (in) compatibility using the screening system Trissel’s™ 2 Compatibility IV-Micromedex 2.0. Parametric and non-parametric statistic were used according to the nature of the variable. Results: 565 pairs of drugs were identified. Of these, 44.9% were compatible; and 8.8%, potentially incompatible. Most potentially incompatible pairs involved substances with alkaline pH such as phenytoin (32%) and sodium bicarbonate (8%) and weak acids such as midazolam (12%) and dobutamine (6%), which could result in precipitate formation. Conclusions: almost half of the mixtures simultaneously administrated was compatible, which indirectly reflects in the organized work between the nursing team and the clinical pharmaceutic in the discussions and decisions related to time scheduling.

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Nursing training on the administration of medication in pediatrics: an assessment of observed and self-reported behavior

Revista Brasileira de Enfermagem ◽

10.1590/0034-7167-2020-1188 ◽

2021 ◽

Vol 74 (4) ◽

Author(s):

Ires Lopes Custódio ◽

Francisca Elisângela Teixeira Lima ◽

Lívia Maia Pascoal ◽

Lorena Pinheiro Barbosa ◽

Patricia Neyva da Costa Pinheiro ◽

...

Keyword(s):

Hand Hygiene ◽

Training Program ◽

Pediatric Patients ◽

Evaluation Study ◽

Intravenous Drugs ◽

Nursing Team ◽

Nursing Professionals ◽

Nursing Training ◽

Three Phases ◽

Observed Behavior

ABSTRACT Objectives: to evaluate the effect of a training program on the administration of intravenous drugs in pediatric patients on the observed and self-reported behavior of the nursing team. Methods: evaluation study carried out with 38 professionals during three phases: Assessment of the behavior observed in the actions performed before training; Training implementation; and Assessment of observed and self-reported behaviors (immediately and six months after training). Results: in the observed behavior, there was an improvement in six (6/12) hand hygiene actions; five (5/14) pertaining to environment Organization, selection, and preparation of materials; and in seven (7/10) referring to the Orientation of the procedure, administration and monitoring of the patient’s reactions. In self-reported behavior, there was an improvement in two (2/8) actions. Conclusions: the training resulted in an improvement in the actions of nursing professionals related to the administration of intravenous medications, both in observed and in self-reported behavior.

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Letters to the Editor

PEDIATRICS ◽

10.1542/peds.51.3.585a ◽

1973 ◽

Vol 51 (3) ◽

pp. 585-586

Author(s):

William A. Neal ◽

John W. Reynolds ◽

Charles W. Jarvis ◽

Hugh J. Williams

Keyword(s):

Sodium Bicarbonate ◽

Umbilical Artery ◽

Thrombus Formation ◽

Alkaline Ph ◽

Rapid Infusion ◽

Letters To The Editor ◽

High Osmolarity ◽

Hyperosmolar Solutions ◽

Bicarbonate Solutions ◽

Very High

As Dr. Helwig suggests, the rapid infusion of substances of very high osmolarity or alkaline pH, such as 50% glucose and THAM, through umbilical artery catheters is potentially harmful. Hyperosmolar solutions are known to cause localized intimal damage, predisposing to thrombus formation. We did not mean to imply that all of the babies in our study continuously received THAM, 50% glucose, and sodium bicarbonate. The maintenance solution was indeed usually 10% dextrose with 200 units heparin/liter added, and many infants with RDS received slow infusions of diluted sodium bicarbonate solutions in doses sufficient to correct metabolic acidosis.

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Administração de medicamento endovenoso em pacientes de hospital de doenças infectocontagiosas: atuação da enfermagem

Enfermagem em Foco ◽

10.21675/2357-707x.2020.v11.n2.2643 ◽

2020 ◽

Vol 11 (2) ◽

Author(s):

Deyse Maria Alves Rocha ◽

Eva Anny Welly de Sousa Brito ◽

Thais Lima Vieira de Souza ◽

Rafaela De Oliveira Mota ◽

Maira De Ciero Miranda ◽

...

Keyword(s):

Patient Safety ◽

Observational Study ◽

Infectious Diseases ◽

Personal Protective Equipment ◽

Protective Equipment ◽

Medical Prescription ◽

Contagious Diseases ◽

Intravenous Drugs ◽

Nursing Team ◽

Nursing Professionals

Objetivo: Avaliar a prática da administração de medicamento endovenosa em pacientes adultos internados em hospital de doenças infectocontagiosas. Metodologia: Estudo descritivo, observacional, desenvolvido em hospital de referência em doenças infectocontagiosas de Fortaleza-CE. Foram realizadas 111 observações de profissionais de enfermagem procedendo à administração de medicamentos endovenosos em pacientes com idade > 18 anos. Resultados: As ações mais realizadas foram: lê a prescrição médica (100%), consegue entender a grafia médica (97,2%) e confere o medicamento relacionado à prescrição (90,6%). Entretanto, as menos executadas foram: acalmar o paciente (21,6%), realizar limpeza da bancada (13,5%), usar equipamento de proteção individual (18,9%), desinfetar ampola ou frasco ampola (11,7%). Conclusão: O estudo mostrou diagnóstico situacional da equipe de enfermagem na atuação do preparo e da administração de medicamentos, caracterizando segurança de pacientes no nível sofrível, segundo o índice de positividade. Descritores: Infusões intravenosas; Segurança do Paciente; Enfermagem.Objective: To evaluate the practice of intravenous drug administration in adult patients hospitalized for infectious-contagious diseases. Methodology: Descriptive, observational study, developed at a referral hospital in infectious diseases of Fortaleza-CE. A total of 111 observations were made by nursing professionals on the administration of intravenous drugs in patients> 18 years of age. Results: The most accomplished actions were: read the medical prescription (100%), can understand the medical script (97.2%) and check the medication related to the prescription (90, 6%). However, the least performed were: calming the patient (21.6%), cleaning the workbench (13.5%), using personal protective equipment (18.9%), disinfect ampoule or ampoule vial (11.7%). Conclusion: The study showed a situational diagnosis of the nursing team in the preparation and administration of medications, characterizing patient safety at the level of suffering, according to the positivity index.Descriptors: Infusions; Intravenous; Patient Safety; Nursing.Objetivo: Evaluar la práctica de la administración de medicamentos endovenosa en pacientes adultos internados en el hospital de enfermedades infectocontagiosas. Metodología: Estudio descriptivo, observacional, desarrollado en un hospital de referencia en enfermedades infectocontagiosas de Fortaleza-CE. Fueron realizadas 111 observaciones de profesionales de enfermería procediendo a la administración de medicamentos endovenosos en pacientes con edad> 18 años. Resultados: Las acciones más realizadas fueron: lee la prescripción médica (100%), consigue entender la caligrafía médica (97,2%) y confirma el medicamento relacionado a la prescripción (90,6%). Sin embargo, las menos ejecutadas fueron: calmar al paciente (21,6%), realizar limpieza de la mesa de trabajo (13,5%), usar equipo de protección individual (18,9 %), desinfectar la ampolla o frasco ampolla (11,7%). Conclusión: El estudio mostró diagnóstico situacional del equipo de enfermería en la actuación de la preparación y de la administración de medicamentos, caracterizando seguridad de pacientes en el nivel sufrible, según el índice de positividad.Descriptores: Infusiones Intravenosas; Seguridad del Paciente; Enfermería.

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Methodology of analysis of very weak acids by isotachophoresis with electrospray-ionization mass-spectrometric detection: Anionic electrolyte systems for the medium-alkaline pH range

Analytica Chimica Acta ◽

10.1016/j.aca.2017.10.013 ◽

2018 ◽

Vol 998 ◽

pp. 67-74 ◽

Cited By ~ 5

Author(s):

Zdena Malá ◽

Petr Gebauer

Keyword(s):

Electrospray Ionization ◽

Mass Spectrometric ◽

Mass Spectrometric Detection ◽

Ionization Mass ◽

Alkaline Ph ◽

Weak Acids ◽

Ph Range ◽

Very Weak Acids

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Ultrastructure of the basal body apparatus in epidermal cells of a sponge larva (Aplysilla SP: Demospongiae)

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s042482010012504x ◽

1992 ◽

Vol 50 (1) ◽

pp. 928-929

Author(s):

R.L. Pinto ◽

R.M. Woollacott

Keyword(s):

Sodium Bicarbonate ◽

Epoxy Resin ◽

Basal Body ◽

Phosphate Buffer ◽

Similar Data ◽

Basal Apparatus ◽

Striated Rootlet ◽

The Common ◽

Basal Foot ◽

Sexually Mature

The basal body and its associated rootlet are the organelles responsible for anchoring the flagellum or cilium in the cytoplasm. Structurally, the common denominators of the basal apparatus are the basal body, a basal foot from which microtubules or microfilaments emanate, and a striated rootlet. A study of the basal apparatus from cells of the epidermis of a sponge larva was initiated to provide a comparison with similar data on adult sponges.Sexually mature colonies of Aplysillasp were collected from Keehi Lagoon Marina, Honolulu, Hawaii. Larvae were fixed in 2.5% glutaraldehyde and 0.14 M NaCl in 0.2 M Millonig’s phosphate buffer (pH 7.4). Specimens were postfixed in 1% OsO4 in 1.25% sodium bicarbonate (pH 7.2) and embedded in epoxy resin. The larva ofAplysilla sp was previously described (as Dendrilla cactus) based on live observations and SEM by Woollacott and Hadfield.

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