VALORIZATION OF Solanum viarum DUNAL BY EXTRACTING BIOACTIVE COMPOUNDS FROM ROOTS AND FRUITS USING ULTRASOUND AND SUPERCRITICAL CO2

The use of clean technologies in the development of bioactive plant extracts has been encouraged, but it is necessary to verify the cytotoxicity and cytoprotection for food and pharmaceutical applications. Therefore, the objective of this work was to obtain the experimental data of the supercritical sequential extraction of murici pulp, to determine the main bioactive compounds obtained and to evaluate the possible cytotoxicity and cytoprotection of the extracts in models of HepG2 cells treated with H2O2. The murici pulp was subjected to sequential extraction with supercritical CO2 and CO2+ethanol, at 343.15 K, and 22, 32, and 49 MPa. Higher extraction yields were obtained at 49 MPa. The oil presented lutein (224.77 µg/g), oleic, palmitic, and linoleic, as the main fatty acids, and POLi (17.63%), POO (15.84%), PPO (13.63%), and LiOO (10.26%), as the main triglycerides. The ethanolic extract presented lutein (242.16 µg/g), phenolic compounds (20.63 mg GAE/g), and flavonoids (0.65 mg QE/g). The ethanolic extract showed greater antioxidant activity (122.61 and 17.14 µmol TE/g) than oil (43.48 and 6.04 µmol TE/g). Both extracts did not show cytotoxicity and only murici oil showed a cytoprotective effect. Despite this, the results qualify both extracts for food/pharmaceutical applications.

Download Full-text

Extraction of bioactive compounds from peach palm pulp (Bactris gasipaes) using supercritical CO2

The Journal of Supercritical Fluids ◽

10.1016/j.supflu.2014.05.010 ◽

2014 ◽

Vol 93 ◽

pp. 2-6 ◽

Cited By ~ 30

Author(s):

Faber A. Espinosa-Pardo ◽

Julian Martinez ◽

Hugo A. Martinez-Correa

Keyword(s):

Bioactive Compounds ◽

Supercritical Co2 ◽

Bactris Gasipaes ◽

Peach Palm

Download Full-text

Mathematical modeling and numerical simulation of the extraction of bioactive compounds from Artocarpus heterophyllus with supercritical CO2

The Journal of Supercritical Fluids ◽

10.1016/j.supflu.2021.105353 ◽

2021 ◽

pp. 105353

Author(s):

Deise Parolo Tramontin ◽

Alexandre Izac Alves ◽

Ariovaldo Bolzan ◽

Marintho Bastos Quadri

Keyword(s):

Mathematical Modeling ◽

Numerical Simulation ◽

Bioactive Compounds ◽

Supercritical Co2 ◽

Artocarpus Heterophyllus

Download Full-text

Supercritical CO2 Extraction of Bioactive Compounds from Mango (Mangifera indica L.) Peel and Pulp

Foods ◽

10.3390/foods10092201 ◽

2021 ◽

Vol 10 (9) ◽

pp. 2201

Author(s):

José Villacís-Chiriboga ◽

Stefan Voorspoels ◽

Maarten Uyttebroek ◽

Jenny Ruales ◽

John Van Camp ◽

...

Keyword(s):

Bioactive Compounds ◽

Supercritical Co2 ◽

Mangifera Indica ◽

Extraction Temperature ◽

Supercritical Co2 Extraction ◽

Bioactive Content ◽

Higher Temperature ◽

Valuable Compounds ◽

By Products ◽

Β Carotene

The potential of supercritical CO2 (SC-CO2) for the extraction of bioactive compounds from mango by-products was assessed. Carotenoid extraction was optimized using a design of experiments based on temperature (35, 55 and 70 °C), pressure (10 and 35 MPa) and co-solvent addition (0%, 10% and 20% of ethanol or acetone). Moreover, the co-extraction of phenolic acids, flavonoids and xanthonoids was evaluated in a subset of parameters. Finally, a comparison was made between SC-CO2 and a two-step organic solvent extraction of the bioactive compounds from the pulp and peel fractions of two Ecuadorian varieties. The optimal extraction temperature was found to be dependent on the bioactive type, with phenolics requiring higher temperature than carotenoids. The optimal overall conditions, focused on maximal carotenoids recovery, were found to be 55 °C, 35 MPa and 20% of ethanol. The main carotenoid was β-carotene, while phenolics differed among the varieties. The bioactive content of the peel was up to 4.1-fold higher than in the pulp fraction. Higher antioxidant activity was found in the extracts obtained with organic solvents. SC-CO2 is a promising technology for the isolation of valuable compounds from mango by-products.

Download Full-text