scholarly journals Health status can predict diaphragmatic muscle thickness in COPD: pilot study

2021 ◽  
Vol 34 ◽  
Author(s):  
Carolina da Rosa Wendpap ◽  
Tamires Daros dos Santos ◽  
Everton Lüdke ◽  
Adriane Schmidt Pasqualoto ◽  
Aron Ferreira da Silveira ◽  
...  
Keyword(s):  
Health Status ◽  
Pilot Study ◽  
Inverse Correlation ◽  
Muscle Thickness ◽  
Rehabilitation Program ◽  
Chronic Obstructive ◽  
Cross Sectional ◽  
Obstructive Pulmonary Disease ◽  
Diaphragmatic Muscle ◽  
Mortality Index

Abstract Introduction: Among the systemic implications of chronic obstructive pulmonary disease (COPD) there are changes in the diaphragm and impact on health status. However, there are few studies on the possible relationship between these variables, and whether health status could predict diaphragmatic muscle thickness (DMT). Objective: To investigate whether there is a relationship between DMT and the prognostic mortality index Body Mass-Index, Airway Obstruction, Dyspnea and Exercise Capacity (BODE), dyspnea and health status, and to investigate whether health status can predict DMT in patients with COPD entering a pulmonary rehabilitation program. Methods: This is a pilot study with a cross-sectional design. Diaphragmatic muscle thickness was evaluated using ultrasound; health status through the COPD Assessment Test (CAT); the sensation of dyspnea by the modified Medical Research Council scale; and mortality, using the BODE index. Results: The sample consisted of 13 patients (68.69 ± 9.3 years) classified as having moderate to severe COPD. There was a strong and inverse correlation between diaphragmatic muscle thickness and health status (r = -0.735; p = 0.004). Simple regression analysis demonstrated that health status influenced diaphragmatic muscle thickness (β = -0.002; IC 95% - 0.004 to -0.001; p = 0.004), explaining 49% of the variance. However, no correlations were observed between diaphragmatic muscle thickness with dyspnea (r = 0.005; p = 0.985) or with the BODE mortality index (r = -0.219; p = 0.472). Conclusion: This pilot study demonstrated a strong inverse correlation between health status and DMT. In addition, health status was able to predict DMT in patients with COPD.

scholarly journals Phenotypic Variation in Patients with Chronic Obstructive Pulmonary Disease in Primary Care

2016 ◽  
Vol 2016 ◽  
pp. 1-9 ◽  
Author(s):  
Emmylou Beekman ◽  
Ilse Mesters ◽  
Mark G. Spigt ◽  
Eva A. M. van Eerd ◽  
Rik Gosselink ◽  
...  
Keyword(s):  
Primary Care ◽  
Health Status ◽  
Airway Obstruction ◽  
Physical Therapist ◽  
Patient Characteristics ◽  
Cross Sectional Study ◽  
Chronic Obstructive ◽  
Cross Sectional ◽  
Obstructive Pulmonary Disease ◽  
Phenotypic Differences

Introduction. Despite the high number of inactive patients with COPD, not all inactive patients are referred to physical therapy, unlike recommendations of general practitioner (GP) guidelines. It is likely that GPs take other factors into account, determining a subpopulation that is treated by a physical therapist (PT). The aim of this study is to explore the phenotypic differences between inactive patients treated in GP practice and inactive patients treated in GP practice combined with PT. Additionally this study provides an overview of the phenotype of patients with COPD in PT practice.Methods. In a cross-sectional study, COPD patient characteristics were extracted from questionnaires. Differences regarding perceived health status, degree of airway obstruction, exacerbation frequency, and comorbidity were studied in a subgroup of 290 inactive patients and in all 438 patients.Results. Patients treated in GP practice combined with PT reported higher degree of airway obstruction, more exacerbations, more vascular comorbidity, and lower health status compared to patients who were not referred to and treated by a PT.Conclusion. Unequal patient phenotypes in different primary care settings have important clinical implications. It can be carefully concluded that other factors, besides the level of inactivity, play a role in referral to PT.

Body Composition, Functional Status and Clinical Outcomes in Patients with Chronic Obstructive Pulmonary Disease

2020 ◽  
Vol 2 (1) ◽  
pp. 01-06
Author(s):  
González Helena
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Airflow Obstruction ◽  
Inverse Correlation ◽  
Cross Sectional Study ◽  
Fat Free Mass ◽  
Chronic Obstructive ◽  
Cross Sectional ◽  
Obstructive Pulmonary Disease ◽  
Muscular Function

Objective: To define the correlation between the Fat Free Mass Index (FFMI), the muscle function, degree of airflow obstruction, the respiratory symptoms and the number of exacerbations during the last year in patients with Chronic Obstructive Pulmonary Disease (COPD). Methods: Prospective and cross-sectional study of subjects older than 40 years with a clinical diagnosis of COPD who underwent measurement of the FFMI and muscular function to determine if these were correlated with the variables of severe COPD. Results: 55 patients Participated in the study. The FFMI was below 32.7% (n=18) and the strength diminished in 56.4% (n=31). In the sample, we found a direct and significant correlation between the FFMI and the FEV1* (predicted %), (p= 0,045). When analyzed by sex, men had a direct correlation between FFMI and the FEV1*(predicted %), (p=0,019), an inverse correlation between FFMI and the spirometric classification of the Global Initiative Obstructive Lung Disease (GOLD) (p=0,008) and between the muscular function and the symptoms (p=0, 03). In women no significant correlation was found. Conclusions: The conditions in mass and the muscular function were correlated with clinical variables and pulmonary function in men, but not in women. We did not find a correlation between corporal composition and the number of exacerbations.

scholarly journals Pain in patients with chronic obstructive pulmonary disease indicated for post-acute pulmonary rehabilitation

2018 ◽  
Vol 16 ◽  
pp. 147997231880945 ◽  
Author(s):  
Eléonore F van Dam van Isselt ◽  
Karin H Groenewegen-Sipkema ◽  
Monica van Eijk ◽  
Niels H Chavannes ◽  
Wilco P Achterberg
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Health Status ◽  
Functional Status ◽  
Pulmonary Disease ◽  
Pulmonary Rehabilitation ◽  
Forced Expiratory Volume ◽  
Chronic Obstructive ◽  
Functional Domain ◽  
Cross Sectional ◽  
Obstructive Pulmonary Disease

Pain is a significant problem in stable chronic obstructive pulmonary disease (COPD) and is associated with other symptoms, worse health status and lower functional status. Not much is known about pain in unstable disease. The primary aim of the present study is to investigate prevalence, characteristics and relationships of pain in patients with COPD hospitalized for an acute exacerbation (AECOPD) and indicated for post-acute pulmonary rehabilitation (PR). This cross-sectional observational study included 149 patients (mean age 70.8 (±7.9) years, 49% male, mean forced expiratory volume in one second as percentage of predicted value 35.3 (±12.6)). Pain was assessed using the brief pain inventory. Functional status and health status were measured using the six-minute walking test (6MWT), the Barthel index (BI) and the clinical COPD questionnaire (CCQ), respectively. Pain was prevalent in 39.6% of all patients. Symptom burden was high, especially in patients with pain. Although we found no difference in objective measurements of functional status (6MWT, BI), patients with pain had clinically relevant lower health status (CCQ), attributed to the functional domain. Pain in patients hospitalized for AECOPD and indicated for post-acute PR is a relevant problem and needs more attention. Incorporation of standard pain assessment during exacerbations and post-acute PR is recommended.

scholarly journals Using the Inflammacheck Device to Measure the Level of Exhaled Breath Condensate Hydrogen Peroxide in Patients With Asthma and Chronic Obstructive Pulmonary Disease (The EXHALE Pilot Study): Protocol for a Cross-Sectional Feasibility Study (Preprint)

2017 ◽  
Author(s):  
Daniel M Neville ◽  
Carole Fogg ◽  
Thomas P Brown ◽  
Thomas L Jones ◽  
Eleanor Lanning ◽  
...  
Keyword(s):  
Hydrogen Peroxide ◽  
Pilot Study ◽  
Airway Inflammation ◽  
Exhaled Breath Condensate ◽  
Symptom Control ◽  
Chronic Obstructive ◽  
Exhaled Breath ◽  
Cross Sectional ◽  
Obstructive Pulmonary Disease ◽  
Breath Condensate

BACKGROUND Asthma and Chronic Obstructive Pulmonary Disease (COPD) are common conditions that affect over 5 million people in the United Kingdom. These groups of patients suffer significantly from breathlessness and recurrent exacerbations that can be difficult to diagnose and go untreated. A common feature of COPD and asthma is airway inflammation that increases before and during exacerbations. Current methods of assessing airway inflammation can be invasive, difficult to perform, and are often inaccurate. In contrast, measurement of exhaled breath condensate (EBC) hydrogen peroxide (H2O2) is performed during normal tidal breathing and is known to reflect the level of global inflammation in the airways. There is a need for novel tools to diagnose asthma and COPD earlier and to detect increased airway inflammation that precedes an exacerbation. OBJECTIVE The aim of this study was to explore the use of a new handheld device (called Inflammacheck) in measuring H2O2 levels in EBC. We will study whether it can measure EBC H2O2 levels consistently and whether it can be used to differentiate asthma and COPD from healthy controls. METHODS We will perform a cross-sectional, feasibility, pilot study of EBC H2O2 levels, as measured by Inflammacheck, and other markers of disease severity and symptom control in patients with asthma and COPD and volunteers with no history of lung disease. Participants will be asked to provide an exhaled breath sample for measurement of their EBC H2O2 using Inflammacheck. The result will be correlated with disease stage, spirometry, fractional exhaled nitric oxide (FeNO), and symptom control scores. RESULTS This study’s recruitment is ongoing; it is anticipated that the results will be available in 2018. CONCLUSIONS The EXhaled Hydrogen peroxide As a marker of Lung diseasE (EXHALE) pilot study will provide an evaluation of a new method of measuring EBC H2O2. It will assess the device’s consistency and ability to distinguish airway inflammation in asthma and COPD compared with healthy controls.

ROLE OF PHARMACIST INTERVENTION ON COPD PATIENTS OF SELECTED AREAS IN CHITRADURGA: A KAP STUDY

2019 ◽  
Vol 8 (2) ◽  
Author(s):  
Melvin K Mathews ◽  
Abubaker Siddiq ◽  
Bharathi D R
Keyword(s):  
Illness Perceptions ◽  
Pharmacist Intervention ◽  
Cross Sectional Study ◽  
Chronic Obstructive ◽  
Cross Sectional ◽  
Obstructive Pulmonary Disease ◽  
Copd Patients ◽  
Post Test ◽  
Knowledge Practice ◽  
And Control

Background: Chronic obstructive pulmonary disease (COPD) is preventable and treatable disease state characterized by air flow limitation that is not fully reversible. Severity of the symptoms is increased during exacerbations. Objectives: The purpose of the study is to assess and improve the knowledge regarding COPD among study subjects. Materials and Methods: A Cross-sectional interventional study was carried out among the peoples in selected areas of the Chitradurga city for a period of six months. Result: A total 207 subjects enrolled in the study in that 155 male and 52 females. In our study mean score of post test was more (5.87±1.68) when compare to pre-test (2.63±1.46) which show significant increase in their knowledge after educating them (p=0.000). A total of 207 subjects were enrolled into the study. SPSS Software was used to calculate the statistical estimation. Paired t-test was used to detect the association status of different variables. Conclusion: The relatively good level of COPD awareness needs to be maintained to facilitate future prevention and control of the disease. This study had identified that negative illness perceptions should be targeted, so that they will not avoid patients from seeking for COPD treatment and adhere to it. Key words: Cross sectional study, Knowledge, practice, COPD.

scholarly journals Association between Physical Activity and Comorbidities in Spanish People with Asthma-COPD Overlap

2021 ◽  
Vol 13 (14) ◽  
pp. 7580
Author(s):  
Sheila Sánchez Castillo ◽  
Lee Smith ◽  
Arturo Díaz Suárez ◽  
Guillermo Felipe López Sánchez
Keyword(s):  
Physical Activity ◽  
Short Form ◽  
National Health Survey ◽  
Lumbar Pain ◽  
Chronic Obstructive ◽  
Cross Sectional ◽  
Obstructive Pulmonary Disease ◽  
Logistic Regression Models ◽  
Adjusted Model ◽  
Activity Questionnaire

Asthma and chronic obstructive pulmonary disease (COPD) are important conditions which often coexist. Higher rates of comorbidities among people with asthma-COPD overlap (ACO) may complicate clinical management. The aim of this study was to determine the prevalence of 30 different comorbidities and to analyze associations between these comorbidities and physical activity (PA) in Spanish people with ACO. Cross-sectional data from the Spanish National Health Survey 2017 were analyzed. A total of 198 Spanish people with ACO aged 15–69 years (60.6% women) were included in this study. PA was measured with the International Physical Activity Questionnaire (IPAQ) short form. Diagnosis of chronic conditions were self-reported. Associations between PA and comorbidities were analyzed using multivariable logistic regression models. The most prevalent comorbidities were chronic allergy (58.1%), chronic lumbar pain (42.4%), chronic cervical pain (38.4%), hypertension (33.3%) and arthrosis (31.8%). A PA level lower than 600 MET·min/week was significantly associated with urinary incontinence (OR = 3.499, 95% CI = 1.369–8.944) and osteoporosis (OR = 3.056, 95% CI = 1.094–8.538) in the final adjusted model. Therefore, the potential influence of PA on reducing the risk of these conditions among people with ACO should be considered, not only because of the health benefits, but also because PA can contribute to a more sustainable world.

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