scholarly journals Dermatophytoses in children: study of 137 cases

2001 ◽  
Vol 43 (2) ◽  
pp. 83-85 ◽  
Author(s):  
Nurimar C. FERNANDES ◽  
Tiyomi AKITI ◽  
Maria da Glória C. BARREIROS
Keyword(s):  
Tinea Pedis ◽  
Tinea Capitis ◽  
Trichophyton Rubrum ◽  
Fungal Infections ◽  
Etiologic Agent ◽  
Microsporum Canis ◽  
Clinical Form ◽  
Tinea Unguium ◽  
The Third ◽  
Few Data

Dermatophytoses are common fungal infections caused by dermatophytes but there are few data about this condition in the childhood. 137 children below the age of 12 and clinically diagnosed as tineas were investigated prospectively at Instituto de Puericultura e Pediatria, Rio de Janeiro, from 1994 to 1999. Hair, skin/nails scraping and pus swabs were collected from lesions and processed for fungus. Male children from 2 to 12 years were mostly affected; tinea capitis (78 cases) mainly caused by Microsporum canis (46 cases) was the most common clinical form. Tinea corporis (43 cases) mainly caused by Trichophyton rubrum (17 cases) accounted for the second most frequent clinical form. Tinea cruris (10 cases) with Trichophyton rubrum (5 cases) as the most common etiologic agent accounted for the third most frequent clinical form. Tinea pedis and tinea unguium were much less frequent (3 cases each). Trichophyton rubrum was the most common etiologic agent isolated in these cases (3 cases).

Skin Infections

2018 ◽  
Author(s):  
Jan V. Hirschmann
Keyword(s):  
Bacterial Infections ◽  
Tinea Pedis ◽  
Viral Infections ◽  
Fungal Infections ◽  
Treatment Options ◽  
Tinea Corporis ◽  
Microsporum Canis ◽  
Plantar Surface ◽  
Fournier Gangrene ◽  
Tinea Versicolor

The skin can become infected by viruses, fungi, and bacteria, including some that ordinarily are harmless colonizing organisms. The most common fungal infections are caused by dermatophytes, which can involve the hair, nails, and skin. Potassium hydroxide (KOH) preparations of specimens from affected areas typically demonstrate hyphae, and either topical or systemic antifungal therapy usually cures or controls the process. The most common bacterial pathogens are Staphylococcus aureus and group A streptococci, which, alone or together, can cause a wide variety of disorders, including impetigo, ecthyma, and cellulitis. Topical antibiotics may suffice for impetigo, but ecthyma and cellulitis require systemic treatment. S. aureus, including methicillin-resistant strains, can also cause furuncles, carbuncles, and cutaneous abscesses. For these infections, incision and drainage without antibiotics are usually curative. Warts are the most common cutaneous viral infection, and eradication can be difficult, especially where the skin is thick, such as the palms and soles, or the patient is immunocompromised. Most therapies consist of trying to destroy the viruses by mechanical, chemical, or immune mechanisms. This review covers dermatophyte infections, yeast infections, bacterial infections, and viral infections of the skin. Figures show the classic annular lesion of tinea corporis, a typical kerion presenting as a zoophilic Microsporum canis infection of the scalp (tinea capitis), tinea corporis, tinea barbae, tinea pedis between and under the toes and on the plantar surface, inflammatory tinea pedis, tinea unguium, tinea manuum, angular cheilitis, prominent satellite lesions of discrete vesicles associated with candidiasis, facial candidiasis, Candida paronychia, tinea versicolor, nonbullous impetigo, bullous impetigo, ecthyma, leg cellulitis, erythema and edema on the cheeks, eyelids, and nose, furuncle, carbuncle, nasal folliculitis, pitted keratolysis, trichomycosis axillaris, necrotizing fasciitis, Fournier gangrene, folliculitis, plantar wart, condyloma acuminatum, and benign lesions of bowenoid papulosis. Tables list dermatophyte species, terminology of dermatophyte infections, topical agents for dermatophyte infections, treatment options for impetigo (adult doses), and treatment options for erythrasma.   This review contains 28 highly rendered figures, 5 tables, and 33 references

ROSEOFUNGIN-AS, OINTMENT 2% FOR TREATMENT OF TINEA PEDIS AND TINEA CORPORIS: RESULTS OF A RANDOMIZED, BLINDED, PROSPECTIVE, MULTICENTER PHASE III CLINICAL TRIAL

2021 ◽  
pp. 29-39
Author(s):  
А.К. САДАНОВ ◽  
В.Э. БЕРЕЗИН ◽  
И.Р. КУЛМАГАМБЕТОВ ◽  
Л.П. ТРЕНОЖНИКОВА ◽  
А.С. БАЛГИМБАЕВА
Keyword(s):  
Clinical Trial ◽  
Candida Albicans ◽  
Tinea Pedis ◽  
Fungal Infections ◽  
Tinea Corporis ◽  
Phase Iii ◽  
Microsporum Canis ◽  
Candida Spp ◽  
Reference Drug ◽  
Phase Iii Clinical Trial

Розеофунгин-АС, мазь 2% для наружного применения разработана для лечения микозов кожи разной этиологии, вызванных дерматофитными, дрожжеподобными и плесневыми грибами. Многоцентровое слепое проспективное рандомизированное исследование проводили в Республике Казахстан для сравнения терапевтической эффективности и безопасности препаратов «Розеофунгин-АС, мазь 2%» и «Клотримазол, крем 1%» при лечении tinea pedis и tinea corporis. Препараты применяли 2 раза в день в течение 28 дней. Лабораторные общеклинические и биохимические обследования пациентов проводили на 0, 14 и 28 дни исследования. Микологическое обследование включало микроскопические и культуральные исследования, которые проводились до лечения и на 28-30-й день после окончания лечения. В клиническое исследование III фазы входили 410 пациентов, включая 290 пациентов с tinea pedis и 120 пациентов с tinea corporis. Лечение препаратом «Розеофунгин-АС, мазь 2%» получали 310 пациентов, лечение препаратом «Клотримазол, крем 1%» - 100 пациентов. У больных обеих групп уже на 14 день уменьшалась выраженность субъективных и объективных проявлений. К 28 дню практически все клинические признаки патологического процесса отсутствовали. Совокупная клинико-микологическая эффективность препарата «Розеофунгин-АС, мазь 2%» составила 99,1%, препарата «Клотримазол, крем 1%» - 98,0%. Препарат «Розеофунгин-АС, мазь 2%» проявил высокую эффективность при лечении грибковых инфекций tinea pedis и tinea corporis, вызванных возбудителями трихофитии (Trihophyton rubrum, T. violarum, T. tonsurans), микроспории (Microsporum canis, M. gypseum), кандидоза (Candida albicans, Candida spp.), плесневыми грибами (Penicillium glaucum). В исследовании не были зафиксированы аллергические реакции и индивидуальная непереносимость исследуемого и референтного препаратов. Препарат «Розеофунгин-АС, мазь 2%» является эффективным антимикотическим средством, клинико-микологическая эффективность которого в терапии микозов кожи составляет 99,1%. Препарат имеет высокий уровень переносимости, безопасности и приемлемости RoseofunginAS, ointment 2% for external use was developed for the treatment of skin mycoses of various etiologies caused by dermatophytic and yeastlike fungi and molds. A multicenter, blind, prospective, randomized trial was conducted in the Republic of Kazakhstan to compare the therapeutic effectiveness and safety of RoseofunginAS, ointment 2% and Clotrimazole, cream 1% in the treatment of tinea pedis and tinea corporis. The drugs were administered twice daily for 28 days. Laboratory general clinical and biochemical examinations of patients were performed on days 0, 14, and 28 of the trial. Mycological examination included microscopic and cultural studies, which were carried out before treatment and on days 2830 after the end of treatment. The Phase III clinical trial involved 410 patients, including 290 with tinea pedis and 120 with tinea corporis. Treatment with RoseofunginAS, ointment 2% was administered to 310 patients, 100 patients were treated with Clotrimazole, cream 1%. In patients of both groups, the severity of subjective and objective manifestations decreased already on day 14. By day 28, almost all clinical signs of the pathological process were absent. The cumulative clinical and mycological effectiveness of the drug RoseofunginAS, ointment 2% was 99.1% and that of the drug Clotrimazole, cream 1% reached 98.0%. The drug RoseofunginAS, ointment 2% exhibited high effectiveness in the treatment of fungal infections, including tinea pedis and tinea corporis, with pathogens that cause trichophytosis (Trihophyton rubrum, T. violarum, T. tonsurans), microsporia (Microsporum canis, M. gypseum), candidiasis (Candida albicans, Candida spp.), and molds (Penicillium glaucum). The study did not record allergic reactions and individual intolerance to the study and reference drug. The drug RoseofunginAS, ointment 2% is an effective antimycotic agent, the clinical and mycological effectiveness of which in the treatment of skin mycoses was 99.1%. The drug possesses a high level of tolerance, safety and acceptability.

Fungal, Bacterial, and Viral Infections of the Skin

2018 ◽  
Author(s):  
Jan V. Hirschmann
Keyword(s):  
Staphylococcus Aureus ◽  
Tinea Pedis ◽  
Viral Infections ◽  
Fungal Infections ◽  
Treatment Options ◽  
Tinea Corporis ◽  
Microsporum Canis ◽  
Methicillin Resistant ◽  
Resistant Strains ◽  
Tinea Versicolor

The skin can become infected by viruses, fungi, and bacteria, including some that ordinarily are harmless colonizing organisms. The most common fungal infections are caused by dermatophytes, which can involve the hair, nails, and skin. Potassium hydroxide (KOH) preparations of specimens from affected areas typically demonstrate hyphae, and either topical or systemic antifungal therapy usually cures or controls the process. The most common bacterial pathogens are Staphylococcus aureus and group A streptococci, which, alone or together, can cause a wide variety of disorders, including impetigo, ecthyma, and cellulitis. Topical antibiotics may suffice for impetigo, but ecthyma and cellulitis require systemic treatment. S. aureus, including methicillin-resistant strains, can also cause furuncles, carbuncles, and cutaneous abscesses. For these infections, incision and drainage without antibiotics are usually curative. Warts are the most common cutaneous viral infection, and eradication can be difficult, especially where the skin is thick, such as the palms and soles, or the patient is immunocompromised. Most therapies consist of trying to destroy the viruses by mechanical, chemical, or immune mechanisms. This review covers dermatophyte infections, yeast infections, bacterial infections, and viral infections of the skin. Figures show the classic annular lesion of tinea corporis, a typical kerion presenting as a zoophilic Microsporum canis infection of the scalp (tinea capitis), tinea corporis, tinea barbae, tinea pedis between and under the toes and on the plantar surface, inflammatory tinea pedis, tinea unguium, tinea manuum, angular cheilitis, prominent satellite lesions of discrete vesicles associated with candidiasis, facial candidiasis, Candida paronychia, tinea versicolor, nonbullous impetigo, bullous impetigo, ecthyma, leg cellulitis, erythema and edema on the cheeks, eyelids, and nose, furuncle, carbuncle, nasal folliculitis, pitted keratolysis, trichomycosis axillaris, necrotizing fasciitis, Fournier gangrene, folliculitis, plantar wart, condyloma acuminatum, and benign lesions of bowenoid papulosis. Tables list dermatophyte species, terminology of dermatophyte infections, topical agents for dermatophyte infections, treatment options for impetigo (adult doses), and treatment options for erythrasma.   This review contains 29 figures, 5 tables, and 33 references. Keywords: Staphylococcus aureus, methicillin-resistant strains, furuncles, carbuncles, cutaneous abscesses, dermatophytes, zoophilic Microsporum canis, andidiasis, facial candidiasis, Candida paronychia, tinea versicolor, nonbullous impetigo, bullous impetigo, ecthyma, leg cellulitis, erythema

scholarly journals Profil dermatofitosis di Poliklinik Kulit dan Kelamin RSUP Prof. Dr. R. D. Kandou Manado periode Januari – Desember 2013

e-CliniC ◽  
2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Cindy E.E.J. Sondakh ◽  
Thigita A. Pandaleke ◽  
Ferra O. Mawu
Keyword(s):  
Stratum Corneum ◽  
Skin Disease ◽  
Tinea Pedis ◽  
Tinea Capitis ◽  
Topical Therapy ◽  
Tinea Corporis ◽  
Age Group ◽  
Tinea Unguium ◽  
Tinea Cruris ◽  
Tinea Barbae

Abstract: Dermatophytosis is a disorder of tissues with keratinized ephithelia e. g. stratum corneum of epidermis, hair, and nails, caused by dermatophyte fungi from arthrodermataceae family. This family has more than 40 species divided into three genera: Epidermophyton, Microsporum, and Trichophyton. The distribution of dermatophytosis is based on its location: tinea capitis, tinea barbae, tinea cruris, tinea pedis et manum, tinea unguium, and tinea corporis. This study aimed to obtain the profile of dermatophytosis classified by location, age, gender, job and therapy at the Dermatovenerology Clinic of Prof. Dr. R. D. Kandou Hospital Manado during the period of January-December 2013. The results showed that of 4,099 skin disease cases in 2013, there were 153 (3.7%) cases of dermatophytosis with the most frequent found was tinea cruris (35.3%), the age group was 45-64 years old (32.7%), most patients were female (60.8%), commonly housewife (22.9%), and the most treatmen tused was topical therapy (68.6%).Keywords: dermatophyte, dermatophytosis, tinea Abstrak: Dermatofitosis merupakan penyakit pada jaringan yang mengandung zat tanduk, seperti stratum korneum pada epidermis, rambut dan kuku, yang disebabkan oleh jamur dermatofita dari famili arthrodermataceae. Famili ini terdiri lebih dari 40 spesies yang dibagi dalam tiga genus: Epidermophyton, Microsporum, dan Trichophyton. Pembagian dermatofitosis berdasarkan lokasinya yaitu tinea kapitis, tinea barbae, tinea kruris, tinea pedis et manum, tinea unguinum, dan tinea korporis. Penelitian ini bertujuan untuk mengetahui profil dermatofitosis di Poliklinik Kulit dan Kelamin RSUP Prof. Dr. R. D. Kandou Manado periode Januari-Desember 2013 berdasarkan klasifikasi lokasi, usia, jenis kelamin, pekerjaan dan terapi yang diberikan. Hasil penelitian menunjukkan bahwa dari total 4.099 kasus penyakit kulit di tahun 2013, terdapat 153 (3,7%) kasus dermatofitosis dengan persentase tertingggi yang diperoleh ialah: tinea kruris (35,3%), golongan umur 45-64 tahun (32,7%), jenis kelamin perempuan (60,8%), ibu rumah tangga (22.9%), dan terapi kombinasi (68.6%) Kata kunci: dermatofitosis, tinea

scholarly journals Potency of Trona on Fungi Associated with Tinea Capitis from Children in Usmanu Danfodiyo University Sokoto (UDUS)

2018 ◽  
pp. 1-6
Author(s):  
M. K. Nata’ala ◽  
A. B. Mormoni ◽  
A. A. Isah ◽  
U. B. Ibrahim ◽  
S. A. Zauro ◽  
...  
Keyword(s):  
Tinea Capitis ◽  
Trichophyton Rubrum ◽  
Trichophyton Mentagrophytes ◽  
Diffusion Method ◽  
Microsporum Canis ◽  
Zone Of Inhibition ◽  
Standard Methods ◽  
Farming Community ◽  
Increased Activity ◽  
Agar Well Diffusion Method

Aim: The potency of trona against fungi associated with dermatophytes isolated from children in Usmanu Danfodiyo University Sokoto (UDUS) local farming community was investigated. Place and Duration of Study: Department of Microbiology, Department of Pure and Applied Chemistry and Department of Pharmacognosy, Usmanu Danfodiyo University, Sokoto, Nigeria, between January 2017 and September 2017. Methodology: The samples were collected from errand children within UDUS, and the organisms were isolated and identified microscopically using standard methods. Elemental analysis of the two types of trona (red and white) was also determined using standard Analytical methods. The sensitivity test was carried out using agar well diffusion method. Results: In the two types of trona (red and white) Sodium was found to have the highest concentration of 9500 mg/kg and 8300 mg/kg, and the lowest was 0.15 and 0.10 mg/kg. Potassium was reported to have a concentration of 4400 mg/kg and 1800 mg/kg for the white and red trona respectively. Some of the organisms identified were Microsporum Canis, Trichophyton rubrum, Trichophyton mentagrophytes etc. Highest mean zone of inhibition of 20.7 and 23.3 mm was recorded for the red and white trona respectively. The least zone of inhibition recorded was 2.7 and 4.7 mm for the red and white trona respectively. Increased activity was recorded when the concentration of the trona was increased. Conclusion: The results revealed promising potentials of trona in the treatment of fungi associated with dermatophytoses. However, further studies should be done to determine the mechanism of action of trona on these organisms.

scholarly journals Efektivitas Air Rebusan dan Air Perasan Lengkuas Merah (Alpinia purpurata K.schum) dalam Menghambat Pertumbuhan Trichophyton rubrum Jamur Penyebab Kutu Air (Tinea pedis)

2018 ◽  
Vol 9 (3) ◽  
pp. 382
Author(s):  
Eka Sulistianingsih ◽  
Mimi Sugiarti
Keyword(s):  
Tinea Pedis ◽  
Trichophyton Rubrum ◽  
Fungal Infections ◽  
Antifungal Drugs ◽  
Minimum Concentration ◽  
Randomized Design ◽  
Soles Of The Feet ◽  
Alpinia Purpurata ◽  
Growth Of Fungi ◽  
Boiled Water

<p><em>Tinea pedis</em> is dermatophytosis in the feet, especially between the fingers and soles of the feet. Chronic fungal infections in the form of peeling and skin rupture are the main manifestations, accompanied by pain and itching. Antifungal drugs have limitations, such as a narrow spectrum of antifungals, adverse effects on certain tissues and resistance to certain antifungals. One of the plants that are used for treatment is red-angled Galangal (<em>Alpinia purpurata K.Schum</em>). The research objective was to compare the effectiveness of boiled water and red galangal juice <em>(Alpinia purpurata K.schum)</em> in inhibiting the growth of fungus Trichophyton rubrum which causes water flea (<em>Tinea pedis</em>). The research was experimental with a completely randomized design (CRD) design. The independent variable is red galangal juice (<em>Alpinia purpurata K.schum</em>) and red galangal boiled water (<em>Alpinia purpurata K.schum</em>) with a concentration of 10%, 20%, 30%, 40%, 50%, 60%, 70%, 80 %, 90%, 100% and the dependent variable is the growth of fungus Trichophyton rubrum. Data analysis used the ANOVA test, followed by the BNT test (Smallest Real Difference) and T-test.The results showed that red galangal boiled water (<em>Alpinia purpurata K.schum</em>) did not have the ability to inhibit the growth of Trichophyton rubrum fungi. Red galangal juice (<em>Alpinia purpurata K.schum</em>) has the ability to inhibit the growth of fungi Trichophyton rubrum and the minimum concentration that can inhibit the growth of fungi Trichophyton rubrum is 10% with a mean inhibitory zone of 24.37 mm.</p>

scholarly journals A case of tinea capitis and tinea unguium caused by Microsporum canis.

1984 ◽  
Vol 25 (3) ◽  
pp. 253-256 ◽  
Author(s):  
Kazuo Fujita ◽  
Kizou Honma ◽  
Katsutaro Nishimoto
Keyword(s):  
Tinea Capitis ◽  
Microsporum Canis ◽  
Tinea Unguium

Epidermophyton floccosum. [Descriptions of Fungi and Bacteria].

1980 ◽  
Author(s):  
P. M. Stockdale
Keyword(s):  
Geographical Distribution ◽  
Tinea Pedis ◽  
Tinea Capitis ◽  
Skin Lesions ◽  
The Body ◽  
Epidermophyton Floccosum ◽  
Tinea Unguium ◽  
Tinea Cruris ◽  
Hen’S Egg

Abstract A description is provided for Epidermophyton floccosum. Information is included on the disease caused by the organism, its transmission, geographical distribution, and hosts. HOSTS: Primarily a pathogen of man (causing mycoses). Also recorded from dog (RMVM 6, 1920) and mouse (RMVM 6, 639). Animal inoculation is rarely successful; the guineapig (RMVM 14, 804), monkey (RMVM 1, 182) and the chorio-allantoic membrane of the hen's egg (RMVM 2, 1676; 4, 82) have been infected experimentally. DISEASE: Ringworm (dermatophytosis, tinea). The groin (tinea cruris, eczema marginatum, dobie itch) and feet (tinea pedis) are most frequently infected. The body (tinea corporis), hands (tinea manuum) and nails (onychomycosis, tinea unguium) may also be infected. Infections of the scalp (tinea capitis) are rare and the hair is never invaded in vivo. Skin lesions are scaling and erythematous, well-marginated with minute vesicopapules in the border. GEOGRAPHICAL DISTRIBUTION: Worldwide.

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