scholarly journals Use of alloplastic meshes in abdominal wounds of rats with induced peritonitis

2014 ◽  
Vol 27 (1) ◽  
pp. 26-29 ◽  
Author(s):  
Rafael Calvão BARBUTO ◽  
Ivana DUVAL-ARAUJO ◽  
Sumara Marques BARRAL ◽  
Raphael Grossi ROCHA ◽  
Cristiane de Souza BECHARA ◽  
...  
Keyword(s):  
Tensile Strength ◽  
Abdominal Wall ◽  
Granulation Tissue ◽  
Abdominal Wall Defect ◽  
Test Group ◽  
Microscopic Analysis ◽  
Female Rats ◽  
Control Group ◽  
Abdominal Wall Defects ◽  
Wall Defect

Background : The use of alloplastic meshes has been historically contra-indicated in patients with infection. Aim : To evaluate the use of polypropylene meshes in the treatment of abdominal wall defects in rats with peritonitis. Methods : Twenty Wistar female rats were divided into two groups: induction of peritonitis (test group) and without peritonitis (control group). An abdominal wall defect was created in all animals, and polypropylene mesh was applied. The evaluation of the tensile strength of the mesh was carried out using tensiometer and microscopic analysis of the healing area was done. Results : More adhesion of the mesh to the rat abdominal wall was observed in test group. The histopathological analyses showed prevalence of moderate to accentuated granulation tissue in both groups, without significant differences. Conclusion : The use of the mesh coverage on abdominal wall defects of rats with induced peritonitis did not show worse results than its use in healthy animals, nor was its integration to the resident tissue any worse.

scholarly journals Investigation of a connection between abdominal wall defects and severity of the herniation in fetuses with gastroschisis and omphalocele

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Natasha T. Logsdon ◽  
Carla M. Gallo ◽  
Luciano Alves Favorito ◽  
Francisco J. Sampaio
Keyword(s):  
Abdominal Wall ◽  
Iliac Crest ◽  
Abdominal Wall Defect ◽  
Control Group ◽  
Abdominal Wall Defects ◽  
Internal Organs ◽  
Wall Defect ◽  
Mean Values ◽  
Biometric Parameters ◽  
Post Test

AbstractAnalyze the biometric parameters and the size (area) of abdominal wall defect (AWD) in fetuses with gastroschisis and omphaloceles and correlate them with the herniated internal organs. We studied 22 fetuses (11 with AWDs and 11 without anomalies). In all fetuses we evaluated the xiphopubic distance (XPD) and iliac crest distance (ICD). In fetuses with AWDs we dissected the abdominal wall and measured the width and length of the defect for calculating its area and studying the correlation between the size of the defect with the organs that were herniated. For statistical analysis, the Anova and Tukey post-test were used (p < 0.05). The XPD in the control group had mean of 4.2 mm (2.3–5.9; SD ± 1.11), while in the AWDs it was 4.2 mm (2.9–5.5; SD ± 0.98) (p = 0.4366). The ICD had mean values of 2.5 mm (1.6–3.4; SD ± 0.58) in the control group, and 2.3 mm (1.2–3.0; SD ± 0.56) in AWDs fetuses (p = 0.6963). The number of herniate organs do not have significant correlation with the area of the defect (r2 = 0.2504, p = 0.5068). There is no correlation between the size (area) of abdominal wall defects and the number of the internal organs that herniated. Therefore, the hole size is not a predictor of the severity of the gastroschisis or omphalocele.

scholarly journals Acellular dermal graft for repair of abdominal wall defects in rabbits

2006 ◽  
Vol 77 (2) ◽  
Author(s):  
A.K. Gangwar ◽  
A.K. Sharma ◽  
Naveen Kumar ◽  
N. Kumar ◽  
S.K. Maiti ◽  
...  
Keyword(s):  
Abdominal Wall ◽  
Abdominal Wall Defect ◽  
Test Group ◽  
Control Group ◽  
Abdominal Wall Defects ◽  
Full Thickness ◽  
Dermal Graft ◽  
Group I ◽  
Group A ◽  
Acellular Dermal

Sixteen clinically healthy New Zealand white rabbits of either sex were divided into 2 equal groups (I and II) of 8 animals each. Under thiopental sodium (2.5 %) anaesthesia a 2 × 3 cm full-thickness abdominal wall defect in the mid-ventral abdominal wall was created and repaired with an acellular dermal graft (ADG) in all the animals of group I (test group). In animals of group II (control group) a full-thickness linear midline abdominal muscular wall incision was made and repaired with a continuous suture pattern using 2-0 nylon.

Left-Sided Gastroschisis

2006 ◽  
Vol 72 (7) ◽  
pp. 637-640 ◽  
Author(s):  
Kenneth W. Gow ◽  
Amina Bhatia ◽  
Daniel F. Saad ◽  
Mark L. Wulkan ◽  
Kurt F. Heiss
Keyword(s):  
Abdominal Wall ◽  
Clinical Course ◽  
Abdominal Wall Defect ◽  
Abdominal Wall Defects ◽  
Wall Defect ◽  
The Right

Gastroschisis is a periumbilical, abdominal wall defect arising to the right of the umbilicus. We describe the clinical course of a left-sided gastroschisis in a term female born at 39 weeks’ gestation. To our knowledge, there have been only 14 left-sided abdominal wall defects reported in the literature. We discuss our case and review the literature to try to determine if there is any clinic difference between right- versus left-sided lesions to make recommendations as to management.

Gastroschisis Is Associated With Placental Delayed Villous Maturation

2019 ◽  
Vol 23 (3) ◽  
pp. 197-203
Author(s):  
Brittany Ruschkowski ◽  
Anthea Lafreniere ◽  
Dina El Demellawy ◽  
David Grynspan
Keyword(s):  
Risk Factors ◽  
Abdominal Wall ◽  
Maternal Age ◽  
Congenital Abnormality ◽  
Abdominal Wall Defect ◽  
Control Group ◽  
Control Groups ◽  
Wall Defect ◽  
Previous Diagnosis ◽  
Kappa Agreement

Gastroschisis is a congenital abnormality characterized by visceral herniation through an abdominal wall defect. While the cause of gastroschisis is unknown, it has been linked to risk factors including young maternal age, smoking, and alcohol use during pregnancy. To date, the only established placental correlate is amniocyte vacuolization. Based on our clinical experience, we hypothesized that delayed villous maturation (DVM) is also associated with gastroschisis. We conducted a retrospective slide review of 23 placentas of neonates with gastroschisis. Additionally, we selected 2 control groups of placentas: 1 with a previous diagnosis of DVM and 1 with normal villous morphology. All placentas were randomized and reviewed by 2 perinatal pathologists, who were blinded to the group; DVM and amniocyte vacuolization were assessed. Gastroschisis was associated with increased placental DVM in 65.2% of cases (vs 13.6% of controls; P = .0007) and increased amniocyte vacuolization in 52.2% of cases (vs 9.1% of controls; P = .003) compared to the control group. Based on the normal and DVM groups, kappa agreement between current slide review and initial pathology diagnosis was 0.419, indicating moderate agreement. Our study shows that gastroschisis is associated with placental DVM. This association may be due to (1) a common upstream factor contributing to both gastroschisis and DVM or (2) DVM may be a consequence of the altered placental and amniotic environment in the context of gastroschisis.

scholarly journals The Oscar Ramirez Procedure, a Solution for Treating Incisional Hernias with Big Abdominal Wall Defect

2014 ◽  
Vol 60 (3) ◽  
pp. 122-124
Author(s):  
M. Gherghinescu ◽  
D. Popa ◽  
A. Panțiru ◽  
C. Russu ◽  
C. Roșca ◽  
...  
Keyword(s):  
Abdominal Wall ◽  
Abdominal Wall Defect ◽  
Postoperative Recovery ◽  
Oblique Muscle ◽  
Abdominal Wall Defects ◽  
Hernia Sac ◽  
Wall Defect ◽  
External Edge ◽  
Incisional Hernias ◽  
Bowel Movements

Abstract Background: Incisional hernias are important complications of abdominal surgery. Normally they are followed by the growth of the hernia sac and an increase of the abdominal wall defect with loss of domain of the herniated organs. Case report: We report a case of a 51 year old female, admitted in the 1st Surgical Clinic of the County Emergency Clinical Hospital of Tîrgu Mureș with a large median reducible incisional hernia and a wall defect of 10/12 cm. The abdominoplasty was performed using the Oscar Ramirez technique, which consists of a longitudinal incision along the aponeurosis of the external oblique muscle, at approximately 1-2 cm from the external edge of the rectus abdominis. This procedure allows the abdominal wall closure. This case is part of a lot of 4 patients who received this treatment using the aforementioned procedure in the past 2 months. Postoperative recovery was favorable, bowel movements were present on the second day after the surgery, the subcutaneous drains were shortened on the fifth day and removed on the sixth. There were no immediate postoperative complications or up to a month after the surgery. The patient was discharged on the seventh day. Conclusions: This technique can be used alone in case of large abdominal wall defects, or prequeling an on-lay mesh procedure addressed to a weak abdominal wall, case in which the functional result is superior to a substitutional mesh.

scholarly journals Rectus Abdominis Muscle Malignant Fibrous Histiocytoma Causing a Large Abdominal Wall Defect: Reconstruction with Biological Mesh

2014 ◽  
Vol 2014 ◽  
pp. 1-3
Author(s):  
Evangelos Falidas ◽  
Stavros Gourgiotis ◽  
Christina Goudeli ◽  
Stavros Mathioulakis ◽  
Konstantinos Vlachos ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Abdominal Wall ◽  
Malignant Fibrous Histiocytoma ◽  
Fibrous Histiocytoma ◽  
Abdominal Wall Defect ◽  
Biological Mesh ◽  
Rectus Abdominis ◽  
Abdominal Wall Defects ◽  
Rectus Abdominis Muscle ◽  
Wall Defect

Malignant fibrous histiocytoma (MFH) is a common soft tissue sarcoma usually involving limbs and retroperitoneum. MFH of the rectus abdominis muscle is extremely rare. Surgery in similar cases leads to large abdominal wall defects needing reconstruction. Biological and synthetic laminar absorbable prostheses are available for the repair of hernia defects in the abdominal wall. They share the important feature of being gradually degraded in the host, resulting the formation of a neotissue. We herein report the case of an 84-year-old man with MFH of the rectus abdominis muscle which was resected and the large abdominal wall defect was successfully repaired with a biological mesh.

One of Curious Congenital Midline Abdominal Defects In Newborn: A Giant Omphalozele In A 3 Years-Old Boy

2021 ◽  
Author(s):  
Stefan Bittmann
Keyword(s):  
Abdominal Wall ◽  
Abdominal Wall Defect ◽  
Abdominal Wall Defects ◽  
Wall Defect ◽  
Lateral Abdominal Wall ◽  
The Third ◽  
Abdominal Organs ◽  
Wall Components ◽  
Congenital Abdominal Wall Defects

Omphalocele is one of the congenital abdominal wall defects and specifically refers to an umbilical ring defect in which the abdominal organs protrude in front of the abdominal wall in a thin sac or membrane. Such an abdominal wall defect develops around the third week of pregnancy due to the failure of adhesion between the embryonic lateral abdominal wall components.

scholarly journals Abdominal wall repair with human acellular dermal autograft

2011 ◽  
Vol 2 (1) ◽  
pp. 6
Author(s):  
Roel E. Genders ◽  
Paul P.G.M. Kouwenberg ◽  
Rob P. Bleichrodt
Keyword(s):  
Abdominal Wall ◽  
Abdominal Wall Defect ◽  
Operative Procedure ◽  
Abdominal Wall Defects ◽  
Dermal Matrix ◽  
Wall Defect ◽  
Mortality And Morbidity ◽  
Acellular Dermis ◽  
Number Of Patients ◽  
Acellular Dermal

Repair of abdominal wall defects in the presence of contamination or infection is a significant problem. The loss of tissue warrants enforcement of the abdominal wall, preferably by autologous material. However, autologous repair often requires extensive surgery. This paper presents a review of available literature of placement of an acellular human dermis to repair an abdominal fascia defect, in contaminated as well as in non-contaminated surgical fields. It is illustrated with a case report that describes the successful reconstruction of an infected abdominal wall defect with a human acellular dermis allograft. A systematic literature review was undertaken with searches performed in the Pubmed and Cochrane databases for the period up till March 2009, using the search terms <em>Alloderm</em> [Substance Name], <em>Hernia</em> [Mesh] and the key words <em>acellular dermis, acellular dermal matrix, human acellular dermal allograft </em>and <em>abdominal wall defect</em>. To assess methodological quality, each article was subjected to a modification of the methodological index for non-randomized studies (MINORS) according to Slim <em>et al.</em> Two items from the original index were not included because none of the studies selected had an unbiased assessment of the study end points and in none of the studies was a prospective calculation of the study size performed. Seventeen studies were included in the review. Data were extracted regarding study design, number of patients, surgical technique, followup period, contaminated or non-contaminated area of the fascia defect, mortality and morbidity (hemorrhage, seroma, wound dehiscence, infection) of the operative procedure, the longterm results (removal of the graft, reherniation and bulging) and level of evidencey. A total of 169 short-term complications and 151 longterm complications occurred after 643 surgical procedures reconstructing both contaminated and clean abdominal wall defects by implantation of an HADA. Human acellular dermal allograft seems to be a good alternative for autologous repair of contaminated or infected abdominal wall defects.

scholarly journals Which mesh should be used to repair abdominal wall defect in peritonitis? An experimental study

2020 ◽  
Vol 7 (2) ◽  
pp. 353
Author(s):  
Hüseyin Alakuş ◽  
Mustafa Göksu
Keyword(s):  
Tensile Strength ◽  
Abdominal Wall ◽  
Abdominal Wall Defect ◽  
Abdominal Wall Defects ◽  
Mesh Group ◽  
Group 4 ◽  
Group 3 ◽  
Group 2 ◽  
Ptfe Mesh ◽  
Group 1

Background: In this study, following the Bogota bag closure of abdominal wall defects created in a rat peritonitis model, the short-term efficacy of polypropylene (PP) mesh (Prolene®, Ethicon), PP Mesh+Seprafilm®, polytetrafluoroethylene (PTFE) mesh [Infinit® Mesh (Gore)] and expanded PTFE (ePTFE) [Dualmesh®plus(Gore)] in the permanent repair of the defects was investigated.Methods: 64 rats were used. The rats were randomized into four groups, each consisting of 16 subjects: PP mesh (Group 1), PP mesh+Seprafilm (Group 2), PTFE mesh (Group 3), and ePTFE mesh (Group 4). Laparotomy was performed and abdominal wall defects were created. Contamination of the peritoneal cavity was induced, and closure was undertaken using a Bogota bag. After three days, the Bogota bag was removed, and materials were placed. At the end of the follow-up period, the rats were sacrificed. Mortality, grade of adhesion, surgical site infection (SSI), and tensile strength were evaluated.Results: Mortality was calculated as 6.3%, 50%, 25%, and 0% for Groups 1, 2, 3, and 4, respectively (p=0.002). Adhesion was observed at a rate of 61.1% in Group 1 and 38.9% in Group 2 (p=0.621). There was no adhesion in Groups 3 and 4 (p=0.001). The rate of SSI was 68.8% in Group 1, %75% in Group 2, and 100% in Groups 3 and 4 (p=0.022). Tensile strength was 2196±193.6 g/cm in Group 1 and 1906±142.1 g/cm in Group 2 (p=0.258).Conclusions: We argue that PP mesh is a suitable prosthesis for the permanent repair of contaminated abdominal wall defects despite the increased adhesion risk.

scholarly journals Expanded polytetrafluoroethylene and polypropylene in the repairing of abdominal wall defects in Wistar rats: comparative study

2006 ◽  
Vol 21 (6) ◽  
pp. 409-415 ◽  
Author(s):  
Armando José d'Acampora ◽  
Fabrícia Slomski Joli ◽  
Ricardo Tramonte
Keyword(s):  
Connective Tissue ◽  
Abdominal Wall ◽  
Polypropylene Mesh ◽  
Wistar Rats ◽  
Fibrous Tissue ◽  
Microscopic Analysis ◽  
Surrounding Tissue ◽  
Control Group ◽  
Abdominal Wall Defects ◽  
Surgical Wound

PURPOSE: To compare the use of polypropylene and PTFE meshes in the treatment of incisional hernias made experimentally on Wistar rats. METHODS: The experiment used 24 Wistar rats divided into three cohorts: C-A (ressection of a segment of abdominal wall), E-A (ressection and placement of PTFEe mesh), E-B (resection and placement of polypropylene mesh). After 28 days, the mesh and the surrounding tissue were removed and submitted to macroscopic analysis (assessment of the abdominal wall for presence of abscess in the surgical wound and/or skin necrosis, and adhesions) as well as microscopic analysis (presence of fibrosis, necrosis and abscess, counting of macrophages, mononuclears and polymorphonuclears). RESULTS: Adhesions and abscesses in the surgical wound were observed more commonly associated to the group treated with PTFEe. The size of the fibrous tissue was greater in the group treated with polypropylene. Cohort E-A showed PTFEe mesh enveloped by organized fine connective tissue. No groups presented necrosis on the site of the insertion. The highest mononuclear inflammatory reaction occurred in association to PTFEe when compared to the control group, but the findings for the polypropylene mesh were also significant when compared to the control group. In the analysis of the results obtained for cohorts E-A and E-B, a minimal occurrence of polymorphonuclears was noticed in both groups, which indicates low tissue reactivity to both materials used in the present experiment. CONCLUSION: Even with epithelization and proliferation of connective tissue, anchorage between PTFEe and abdominal wall is insufficient, which can result in reherniations.

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