scholarly journals Risk factors associated with adverse reactions to antituberculosis drugs

2015 ◽  
Vol 41 (1) ◽  
pp. 77-89 ◽  
Author(s):  
Laíse Soares Oliveira Resende ◽  
Edson Theodoro dos Santos-Neto
Keyword(s):  
Risk Factors ◽  
Adverse Reactions ◽  
Scientific Evidence ◽  
Acetylator Phenotype ◽  
Health Care Facilities ◽  
Public Health Care ◽  
Antituberculosis Drugs ◽  
Factors Associated ◽  
Treatment Regimens ◽  
Care Facilities

This review sought to identify the available scientific evidence on risk factors associated with adverse reactions to antituberculosis drugs. We performed a systematic review of studies published in the 1965-2012 period and indexed in the MEDLINE and LILACS databases. A total of 1,389 articles were initially selected. After reading their abstracts, we selected 85 studies. Of those 85 studies, 16 were included in the review. Risk factors for adverse reactions to antituberculosis drugs included age > 60 years, treatment regimens, alcoholism, anemia, and HIV co-infection, as well as sodium, iron, and albumin deficiency. Protective factors against hepatic adverse effects of antituberculosis drugs included being male (combined OR = 0.38; 95% CI: 0.20-0.72) and showing a rapid/intermediate N-acetyltransferase 2 acetylator phenotype (combined OR = 0.41; 95% CI: 0.18-0.90). There is evidence to support the need for management of adverse reactions to antituberculosis drugs at public health care facilities.

scholarly journals Delayed access to treatment and frequency of acute respiratory infection as risk factors of severe pneumonia among children aged 12-59 months in Denpasar, Bali

2017 ◽  
Vol 5 (1) ◽  
pp. 61
Author(s):  
Dewa Ayu Ketut Sri Abadi ◽  
Dewa Nyoman Wirawan ◽  
Anak Agung Sagung Sawitri ◽  
I Gusti Ayu Trisna Windiani
Keyword(s):  
Risk Factors ◽  
Health Care ◽  
Access To Health Care ◽  
Respiratory Infections ◽  
Severe Pneumonia ◽  
Health Care Facilities ◽  
First Episode ◽  
Access To Treatment ◽  
Healthcare Facilities ◽  
Care Facilities

Background and purpose: Period prevalence of pneumonia among children in Indonesia increased from 2.1 in 2007 to 2.7 per 1000 children in 2013. The highest incidence was found among children aged 12-23 months. This study aims to examine association between delayed access to health care facilities and severity of children pneumonia.Methods: A case control study was conducted in Denpasar City. A total of 132 children were recruited to participate in this study, consisted of 44 cases and 88 controls. Cases were selected from 161 children with severe pneumonia who registered at Pulmonology Department of Sanglah General Hospital between January 2015 to April 2016. Controls were selected from 261 children aged 12-59 months with mild pneumonia who visited out-patient service at all community health centres in Denpasar City between January 2015 and April 2016. Cases and controls were matched by sex. Data were collected by interview with the parents in their houses. Data were analysed using multivariate analysis with logistic regression.Results: Risk factors associated to severity of pneumonia among children aged 12-59 months were delayed access to treatment for more than three days (AOR=2.15;95%CI: 1.39-3.32), non-health care facilities at first episode of illness (AOR=4.02; 95%CI: 1.53-10.61) and frequent episodes of respiratory infections (>4 times) over the last 6 months (AOR=5.45; 95%CI: 2.13-13.96).Conclusion: Delayed access to treatment, did not access healthcare facilities at first episode of illness, and high frequency of acute respiratory infections are risk factors of severe pneumonia among children.

Spatial distribution of public health care facilities in rural areas of Nalanda district, Bihar

2020 ◽  
Vol 66 (4) ◽  
pp. 387-399
Author(s):  
Anand Kumar ◽  
◽  
Dhiraj Kumar Sharma ◽  
Satya Prakash ◽  
Ram Sakal Yadava ◽  
...  
Keyword(s):  
Public Health ◽  
Health Care ◽  
Spatial Distribution ◽  
Community Development ◽  
Rural Areas ◽  
Graphical Representation ◽  
Health Care Facilities ◽  
Public Health Care ◽  
Location Quotient ◽  
Care Facilities

At this critical juncture of time when the whole world is facing a health care emergency due to the occurrence of (SARS-CoV-2) pandemic. It becomes necessary to critically evaluate public health care facilities and their availability to common people to tackle the ongoing crisis rationally. In this regard, this paper tries to study the spatial distribution of public health care facilities and their availability in rural areas of Nalanda district. Location quotient, Lorenz curve and Gini's coefficient have been worked out to find unequal concentration, availability and distribution of public health care facilities across the study area. To show the concentration and distribution of health care facilities over space maps have been drawn on ArcGIS. MS Excel and Word have been used for showing the availability of health care facilities through graphical representation and for tabulation purposes. This paper concludes that community development blocks surrounding district headquarter have a higher concentration and larger availability of rural public health care facilities in comparison to peripheral community development blocks of the study area.

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