scholarly journals Systematic review of the literature on vitamin A and memory

2012 ◽  
Vol 6 (4) ◽  
pp. 219-222 ◽  
Author(s):  
Yara Dadalti Fragoso ◽  
Niklas Söderberg Campos ◽  
Breno Faria Tenrreiro ◽  
Fernanda Jussio Guillen
Keyword(s):  
Systematic Review ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Vitamin A ◽  
Evidence Based ◽  
Review Of The Literature ◽  
Vitamin A Supplementation ◽  
Treatment And Prevention ◽  
The Subject

ABSTRACT Background: Over the last 30 years, a variety of studies reporting the effects of vitamin A on memory have been published. Objective: To perform a rigorous systematic review of the literature on vitamin A and memory in order to organize evidence-based data on the subject. Methods: Four authors carried out the systematic review in accordance with strict guidelines. The terms "vitamin A" OR "retinol" OR "retinoic acid" AND "memory" OR "cognition" OR "Alzheimer" were searched in virtually all medical research databases. Results: From 236 studies containing the key words, 44 were selected for this review, numbering 10 reviews and 34 original articles. Most studies used animal models for studying vitamin A and cognition. Birds, mice and rats were more frequently employed whereas human studies accounted for only two reports on brain tissue from autopsies and one on the role of isotretinoin in cognition among individuals taking this medication to treat acne. Conclusion: Vitamin A may be an important and viable complement in the treatment and prevention of Alzheimer's disease. Clinical trials are imperative and, at present, there is no evidence-based data to recommend vitamin A supplementation for the prevention or treatment of Alzheimer's disease.

scholarly journals Clinical Assessment of Amyloid Imaging in Alzheimer's Disease: A Systematic Review of the Literature

2013 ◽  
Vol 36 (5-6) ◽  
pp. 263-278 ◽  
Author(s):  
Philip Wahlster ◽  
Charlotte Niederländer ◽  
Christine Kriza ◽  
Sandra Schaller ◽  
Peter L. Kolominsky-Rabas
Keyword(s):  
Systematic Review ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Clinical Assessment ◽  
Amyloid Imaging ◽  
Review Of The Literature

scholarly journals The role of psychiatrists in developing the skills of dementia care workers

2011 ◽  
Vol 17 (5) ◽  
pp. 372-380 ◽  
Author(s):  
Julian Mason ◽  
Adetokunbo Adeshina
Keyword(s):  
Mental Health ◽  
Systematic Review ◽  
Community Mental Health ◽  
Antipsychotic Medication ◽  
Evidence Based ◽  
Review Of The Literature ◽  
People With Dementia ◽  
Care Workers ◽  
Core Features

SummaryA recommendation of the UK's National Dementia Strategy is to develop the skills of the care workers who provide day-to-day care for people with dementia. On the basis of a systematic review of the literature, we suggest evidence-based areas in which the skills of care workers can be developed to reduce the incidence of difficult behaviour and the use of antipsychotic medication in dementia. We discuss core features of carer training, education and practice. Psychiatrists involved in the training of carers can teach new skills to carers. Psychiatrists in community mental health teams can, through leadership and clinical liaison, reinforce and enable these skills in care homes, domiciliary services and in-patient settings serving people with dementia.

scholarly journals Neuroprotective Role of Phytochemicals

Molecules ◽  
2018 ◽  
Vol 23 (10) ◽  
pp. 2485 ◽  
Author(s):  
Bharath Velmurugan ◽  
Baskaran Rathinasamy ◽  
Bharathi Lohanathan ◽  
Varadharajan Thiyagarajan ◽  
Ching-Feng Weng
Keyword(s):  
Alzheimer’S Disease ◽  
Parkinson’S Disease ◽  
Alzheimer's Disease ◽  
Parkinson's Disease ◽  
Side Effects ◽  
Neurodegenerative Diseases ◽  
Evidence Based ◽  
Extensive Investigation ◽  
Potential Efficacy

Neurodegenerative diseases are normally distinguished as disorders with loss of neurons. Various compounds are being tested to treat neurodegenerative diseases (NDs) but they possess solitary symptomatic advantages with numerous side effects. Accumulative studies have been conducted to validate the benefit of phytochemicals to treat neurodegenerative diseases including Alzheimer’s disease (AD) and Parkinson’s disease (PD). In this present review we explored the potential efficacy of phytochemicals such as epigallocatechin-3-galate, berberin, curcumin, resveratrol, quercetin and limonoids against the most common NDs, including Alzheimer’s disease (AD) and Parkinson’s disease (PD). The beneficial potentials of these phytochemicals have been demonstrated by evidence-based but more extensive investigation needs to be conducted for reducing the progression of AD and PD.

The role of egocentric and allocentric abilities in Alzheimer's disease: A systematic review

2014 ◽  
Vol 16 ◽  
pp. 32-44 ◽  
Author(s):  
Silvia Serino ◽  
Pietro Cipresso ◽  
Francesca Morganti ◽  
Giuseppe Riva
Keyword(s):  
Systematic Review ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease

The Possible Role of Antioxidant Vitamin C in Alzheimer’s Disease Treatment and Prevention

2013 ◽  
Vol 28 (2) ◽  
pp. 120-125 ◽  
Author(s):  
Jae-Hyeok Heo ◽  
Hyon-Lee ◽  
Kyoung-Min Lee
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Vitamin C ◽  
Neurodegenerative Disorder ◽  
Therapeutic Potential ◽  
Acetylcholinesterase Activity ◽  
Antioxidant Vitamin ◽  
Treatment And Prevention ◽  
Current Article

Oxidative stress is suggested to play a major role in the pathogenesis of Alzheimer’s disease (AD). Among the antioxidants, vitamin C has been regarded as the most important one in neural tissue. It also decreases β-amyloid generation and acetylcholinesterase activity and prevents endothelial dysfunction by regulating nitric oxide, a newly discovered factor in the pathogenesis and progression of AD. However, clinical trials using antioxidants, including vitamin C, in patients with AD yielded equivocal results. The current article discusses the relevance of vitamin C in the cellular and molecular pathogenesis of AD and explores its therapeutic potential against this neurodegenerative disorder.

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