A CHROMATOGRAPHIC INVESTIGATION OF Δ4-3-KETOSTEROIDS AND α-KETOLIC STEROIDS IN HUMAN URINE

1953 ◽  
Vol 9 (4) ◽  
pp. 401-417 ◽  
Author(s):  
CONSTANCE de COURCY ◽  
I. E. BUSH ◽  
C. H. GRAY ◽  
J. BARBARA LUNNON
Keyword(s):  
Paper Chromatography ◽  
Human Urine ◽  
The Other ◽  
Additional Material ◽  
The Third ◽  
Neutral Ph ◽  
Chromatographic Investigation ◽  
Final Fraction ◽  
Conjugated Steroids

The Δ4-3-ketosteroids and α-ketolic steroids present in extracts prepared by five different procedures from urine have been examined by paper chromatography. The first extract, which consisted of those steroids extractable with chloroform at neutral pH contained cortisone and cortisol* and one to four unknown Δ4-3-ketosteroids. The second extract, representing steroids extractable immediately after acidification to pH 1 contained very little additional material. The third fraction consisted of extra steroids liberated after standing for 24 hr with acid; this rarely contained any detectable steroid material. A fraction which contained chloroform-soluble conjugated steroids was found to include small quantities of cortisone and cortisol and the other Δ4-3-ketosteroids. The final fraction contained large quantities of steroids liberated by hydrolysis with β-glucuronidase; these were mainly α-ketolic steroids including pregnane-3α: 17α: 21-triol-11: 20-dione, together with other unknown Δ4-3-ketosteroids. The distribution of the steroids in the various fractions is discussed and suggestions are made concerning the possible structure of some of the unknown steroids.

Distribution and abundance of the pelagic processid, Processa pippinae Wicksten & Méndez, 1985 (Decapoda, Caridea, Processidae), collected during the TALUD XIV cruise in the Gulf of California, Mexico, and description of a new genus

Crustaceana ◽  
2012 ◽  
Vol 85 (4-5) ◽  
pp. 463-472 ◽  
Author(s):  
Michel E. Hendrickx
Keyword(s):  
Posterior Margin ◽  
Gulf Of California ◽  
New Genus ◽  
Morphological Characteristics ◽  
The Other ◽  
Dorsal Margin ◽  
Posterior Lobe ◽  
Additional Material ◽  
Abdominal Somite ◽  
The Third

The pelagic processid, Processa pippinae Wicksten & Méndez, 1985, has been reported previously as an endemic species in the northern Gulf of California, Mexico. Additional material collected accidentally in a benthic sledge and with a mid-water micronecton net is reported, including a series of small-sized specimens (CL 2.2 mm). The shape of the laterally compressed rostrum of this species varies considerably with size and among adult specimens. Based on several morphological characteristics of P. pippinae, a new genus, Maryprocessa, is proposed. Several unique characteristics separate Maryprocessa new genus from the other five genera of Processidae, including the laterally compressed rostrum overreaching the cornea, unique among the Processidae, the extraordinary long antennal and antennular flagella, the posterior lobe on the dorsal margin of the third abdominal somite, and the long, acute pair of spines on the posterior margin of the sixth abdominal somite.

Rapid Isolation of High Molecular Weight Urokinase from Native Human Urine

1982 ◽  
Vol 47 (03) ◽  
pp. 197-202 ◽  
Author(s):  
Kurt Huber ◽  
Johannes Kirchheimer ◽  
Bernd R Binder
Keyword(s):  
Molecular Weight ◽  
High Molecular Weight ◽  
Human Urine ◽  
Gel Filtration ◽  
Chain Structure ◽  
The Other ◽  
Single Chain ◽  
Apparent Homogeneity ◽  
Sequential Adsorption

SummaryUrokinase (UK) could be purified to apparent homogeneity starting from crude urine by sequential adsorption and elution of the enzyme to gelatine-Sepharose and agmatine-Sepharose followed by gel filtration on Sephadex G-150. The purified product exhibited characteristics of the high molecular weight urokinase (HMW-UK) but did contain two distinct entities, one of which exhibited a two chain structure as reported for the HMW-UK while the other one exhibited an apparent single chain structure. The purification described is rapid and simple and results in an enzyme with probably no major alterations. Yields are high enough to obtain purified enzymes for characterization of UK from individual donors.

Efficacy of some insecticide modules against major insect pests and spider population of rice, Oryza sativa L.

ENTOMON ◽  
2018 ◽  
Vol 43 (4) ◽  
pp. 257-262
Author(s):  
Atanu Seni ◽  
Bhimasen Naik
Keyword(s):  
Oryza Sativa ◽  
Grain Yield ◽  
Untreated Control ◽  
Insect Pests ◽  
Oryza Sativa L ◽  
Gall Midge ◽  
Stem Borer ◽  
The Other ◽  
The Third ◽  
Treated Plot

Experiments were carried out to assess some insecticide modules against major insect pests of rice. Each module consists of a basal application of carbofuran 3G @ 1 kg a.i ha-1 at 20 DAT and Rynaxypyr 20 SC @ 30 g a.i ha-1 at 45 DAT except untreated control. All modules differ with each other only in third treatment which was applied in 65 DAT. The third treatment includes: Imidacloprid 17.8 SL @ 27 g a.i ha-1, Pymetrozine 50 WG @ 150 g a.i ha-1, Triflumezopyrim 106 SC @ 27 g a.i ha-1, Buprofezin 25 SC @ 250 g a.i ha-1; Glamore (Imidacloprid 40+Ethiprole 40% w/w) 80 WG @ 100 g a.i. ha-1, Thiacloprid 24 SC @ 60 g a.i ha-1, Azadirachtin 0.03 EC @ 8 g a.i ha-1, Dinotefuran 20 SG@ 40 g a.i ha-1 and untreated control. All the treated plots recorded significantly lower percent of dead heart, white ear- head caused by stem borer and silver shoot caused by gall midge. Module with Pymetrozine 50 WG @ 150 g a.i ha-1 treated plot recorded significantly higher per cent reduction of plant hoppers (>80% over untreated control) and produced higher grain yield (50.75 qha-1) than the other modules. Among the different treated modules the maximum number of spiders was found in Azadirachtin 0.03 EC @ 8 g a.i ha-1 treated module plot followed by other treatments.

ALDOSTERONE STIMULATION IN VITRO

1965 ◽  
Vol 50 (2) ◽  
pp. 301-309 ◽  
Author(s):  
Jürg Müller
Keyword(s):  
Ammonium Chloride ◽  
Human Urine ◽  
Incubation Medium ◽  
The Other ◽  
Ammonium Ions ◽  
Response Curves ◽  
Urine Extract ◽  
Similar Dose ◽  
Aldosterone Production

ABSTRACT An extract of human urine, which was previously shown to stimulate aldosterone production by rat adrenal sections, was further purified. Evidence was obtained that its aldosterone-stimulating effect was due to the presence of ammonium ions. Addition of ammonium chloride and of urine extract to the incubation medium caused identical increases in aldosterone production in vitro. In addition to ammonium ions, rubidium and caesium ions also stimulated aldosterone production up to 250% that of control values without a significant effect on corticosterone production. Similar dose-response curves were obtained when increasing concentrations of potassium, ammonium, rubidium and caesium ions were tested. Aldosterone production was maximal at concentrations of 7 mval/1 and was significantly lower at higher concentrations. When ammonium chloride and ACTH were simultaneously added to the incubation medium, the production of aldosterone and of corticosterone was lower than with ACTH alone. On the other hand, the stimulating activity on aldosterone and corticosterone production by »TPN« (NADP) and glucose-6-phosphate was enhanced by the simultaneous addition of ammonium chloride.

A SIMPLE METHOD FOR THE DETECTION OF URINARY UNCONJUGATED CORTISOL BY PAPER CHROMATOGRAPHY

1964 ◽  
Vol 47 (3) ◽  
pp. 466-468 ◽  
Author(s):  
S. B. Pal
Keyword(s):  
Paper Chromatography ◽  
Human Urine ◽  
Specific Method ◽  
Simple Method ◽  
Normal Human

ABSTRACT Unconjugated corticosteroids are extracted from normal human urine and the urine of patients with rheumatic disorders treated with synthetic corticosteroids and corticotrophin. A simple and specific method using paper chromatography has been developed to detect the unconjugated cortisol in urine.

Retroaktive Neuverhandlung

2018 ◽  
Vol 63 (1) ◽  
Author(s):  
Daniel Martin Feige
Keyword(s):  
Original Work ◽  
The Other ◽  
Final Part ◽  
Critical Reading ◽  
The Third ◽  
Works Of Art ◽  
The Relationship

Der Beitrag widmet sich der Frage historischer Folgeverhältnisse in der Kunst. Gegenüber dem Gedanken, dass es ein ursprüngliches Werk in der Reihe von Werken gibt, das späteren Werken seinen Sinn gibt, schlägt der Text vor, das Verhältnis umgekehrt zu denken: Im Lichte späterer Werke wird der Sinn früherer Werke neu ausgehandelt. Dazu geht der Text in drei Schritten vor. Im ersten Teil formuliert er unter der Überschrift ›Form‹ in kritischer Abgrenzung zu Danto und Eco mit Adorno den Gedanken, dass Kunstwerke eigensinnig konstituierte Gegenstände sind. Die im Gedanken der Neuverhandlung früherer Werke im Lichte späterer Werke vorausgesetzte Unbestimmtheit des Sinns von Kunstwerken wird im zweiten Teil unter dem Schlagwort ›Zeitlichkeit‹ anhand des Paradigmas der Improvisation erörtert. Der dritte und letzte Teil wendet diese improvisatorische Logik unter dem Label ›Neuaushandlung‹ dann dezidiert auf das Verhältnis von Vorbild und Nachbild an. The article proposes a new understanding of historical succession in the realm of art. In contrast to the idea that there is an original work in the series of works that gives meaning to the works that come later, the text proposes to think it exactly the other way round: in the light of later works, the meanings of earlier works are renegotiated. The text proceeds in three steps to develop this idea. Under the heading ›Form‹ it develops in the first part a critical reading of Danto’s and Eco’s notion of the constitution of the artworks and argues with Adorno that each powerful work develops its own language. In the second part, the vagueness of the meaning of works of art presupposed in the idea of renegotiating earlier works in the light of later works is discussed under the term ›Temporality‹ in terms of the logic of improvisation. The third and final part uses this improvisational logic under the label ›Renegotiation‹ to understand the relationship between model and afterimage in the realm of art.

Features of the course and treatment of glaucoma during pregnancy

2020 ◽  
Vol 98 (3) ◽  
pp. 178-184
Author(s):  
T. V. Chernyakova ◽  
A. Yu. Brezhnev ◽  
I. R. Gazizova ◽  
A. V. Kuroyedov ◽  
A. V. Seleznev
Keyword(s):  
Pregnant Women ◽  
Laser Treatment ◽  
Progressive Disease ◽  
Clinical Course ◽  
The Other ◽  
Third Trimester ◽  
The Third ◽  
Chronic Progressive Disease ◽  
Hypotensive Therapy ◽  
Eye Pressure

In the review we have integrated all up-to-date knowledge concerning clinical course and treatment of glaucoma among pregnant women to help specialists choose a proper policy of treatment for such a complicated group of patients. Glaucoma is a chronic progressive disease. It rarely occurs among childbearing aged women. Nevertheless the probability to manage pregnant patients having glaucoma has been recently increasing. The situation is complicated by the fact that there are no recommendations on how to treat glaucoma among pregnant women. As we know, eye pressure is progressively going down from the first to the third trimester, so we often have to correct hypotensive therapy. Besides, it is necessary to take into account the effect of applied medicines on mother health and evaluate possible teratogenic complications for a fetus. The only medicine against glaucoma which belongs to category B according to FDA classification is brimonidine. Medicines of the other groups should be prescribed with care. Laser treatment or surgery may also be a relevant decision when monitoring patients who are planning pregnancy or just bearing a child. Such treatment should be also accompanied by medicines.

The Nile Delta during the Early Dynastic and Old Kingdom periods. Preliminary remarks on the evolution of settlement landscape

2020 ◽  
pp. 13-61
Author(s):  
Natalia Małecka-Drozd
Keyword(s):  
Nile Delta ◽  
Ancient Egypt ◽  
The Other ◽  
Old Kingdom ◽  
The Third ◽  
Other Hand ◽  
Early Dynastic ◽  
Territorial Structure ◽  
Settlement Landscape ◽  
New Settlements

The 3rd millennium BC appears to be a key period of development of the historical settlement landscape in ancient Egypt. After the unification of the country, the process of disappearance of the predynastic socio-political structures and settlement patterns associated with them significantly accelerated. Old chiefdoms, along with their centres and elites, declined and vanished. On the other hand, new settlements emerging in various parts of the country were often strictly related to the central authorities and formation of the new territorial administration. Not negligible were climatic changes, which influenced the shifting of the ecumene. Although these changes were evolutionary in their nature, some important stages may be recognized. According to data obtained during surveys and excavations, there are a number of sites that were considerably impoverished and/or abandoned before and at the beginning of the Old Kingdom. On the other hand, during the Third and Fourth Dynasties some important Egyptian settlements have emerged in the sources and begun their prosperity. Architectural remains as well as written sources indicate the growing interest of the state in the hierarchy of landscape elements and territorial structure of the country.

Avoiding Shame and Guilt

2018 ◽  
Author(s):  
C. Daniel Batson
Keyword(s):  
Empathic Concern ◽  
The Other ◽  
The Third ◽  
Helping Relationship ◽  
Shame And Guilt

After rejecting the remove–empathy hypothesis (Chapter 4), attention turned to the other two classic egoistic explanations for the motivation to help produced by empathic concern: empathy-specific punishment and empathy-specific reward. This chapter considers two kinds of empathy-specific punishment, shame and guilt. The shame hypothesis claims that we help more when we feel empathic concern because we’re motivated to avoid disapproval and censure from others. The guilt hypothesis says that we’re motivated to avoid self-condemnation for failing to do what we should. Contradicting the shame hypothesis, experiments revealed that even when no one else will know if participants fail to help, empathy still increased helping. Contradicting the guilt hypothesis, participants induced to feel empathy helped more even when provided a good excuse for not helping. Given that neither form of empathy-specific punishment could account for the empathy–helping relationship, our search shifted to the third classic egoistic explanation: pursuing pride.

Introduction

2017 ◽  
Author(s):  
Patrick Colm Hogan
Keyword(s):  
Queer Theory ◽  
Social Constructionism ◽  
The Other ◽  
Sexual Identities ◽  
The Third ◽  
Sexuality And Gender ◽  
And Gender ◽  
Sexual Part ◽  
The One ◽  
And Behavior

The introduction first sets out some preliminary definitions of sex, sexuality, and gender. It then turns from the sexual part of Sexual Identities to the identity part. A great deal of confusion results from failing to distinguish between identity in the sense of a category with which one identifies (categorial identity) and identity in the sense of a set of patterns that characterize one’s cognition, emotion, and behavior (practical identity). The second section gives a brief summary of this difference. The third and fourth sections sketch the relation of the book to social constructionism and queer theory, on the one hand, and evolutionary-cognitive approaches to sex, sexuality, and gender, on the other. The fifth section outlines the value of literature in not only illustrating, but advancing a research program in sex, sexuality, and gender identity. Finally, the introduction provides an overview of the chapters in this volume.

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