scholarly journals Impact of transportation on foundry coke quality

2020 ◽  
Vol 63 (10) ◽  
pp. 823-828
Author(s):  
E. O. Pobegalova ◽  
V. A. Ivanova
Keyword(s):  
Experimental Studies ◽  
Size Fraction ◽  
Real Life ◽  
Air Humidity ◽  
Foundry Coke ◽  
Coke Plants ◽  
Durability Index ◽  
Transportation Distance ◽  
The Impact

The quality metrics of foundry coke are determined by testing at coke plants. Foundry coke consumers are foundry enterprises which are usually located far from the coke plants. Foundry coke is transported in bulk in open railway wagons. Therefore, this paper is aimed to determine the impact of transportation on the quality of foundry coke. The test conditions were as close as possible to real life conditions of foundry coke transportation. To estimate the impact of transportation distance we introduced the destruction index Pт (%). The results of experimental studies have shown that the destruction of foundry coke is not the same at different intervals of transportation. When transporting up to 300 km, the coke with the minimum durability index M40 is destroyed. When the distance is increased from 900 km up to 2500 km, the foundry coke destruction index (Pт , %) increases by 2.08 – 3.02 % depending on the batch. For all batches, a size fraction of less than 40 mm was noted depending on the durability index M40 from 0.25 to 1.41 %. The size fraction of more than 80 mm stays the same for foundry coke with higher durability indices. When the air humidity rises by 40 % during transportation, the amount of moisture in the coke samples of a 40 – 60 mm size fraction is more than 24 times higher than usual, a 60 – 80 mm size fraction – more than 17 times, an 80 mm and larger – more than 10 times. When the air humidity decreases by 34 %, the amount of moisture in a gram of coke of a 40 – 60 mm size fraction becomes 2 times lower than usual, a 60 – 80 mm size fraction – 1.26 times, an 80 mm and larger – 1.45 times. Compared to coke of size fractions 60 – 80 mm and 80 mm and larger, the moisture of the 40 – 60 mm size fraction coke grows faster when the air humidity increases as well.

scholarly journals Impact of eating disorders on paid or unpaid work participation and performance: a systematic review and meta-analysis protocol

2022 ◽  
Vol 10 (1) ◽  
Author(s):  
Fatima Safi ◽  
Anna M. Aniserowicz ◽  
Heather Colquhoun ◽  
Jill Stier ◽  
Behdin Nowrouzi-Kia
Keyword(s):  
Systematic Review ◽  
Eating Disorders ◽  
Meta Analysis ◽  
Experimental Studies ◽  
Work Participation ◽  
Unpaid Work ◽  
Cochrane Library ◽  
And Performance ◽  
The Impact

Abstract Background Eating disorders (ED) can reduce quality of life by limiting participation and performance in social and occupational roles, including paid or unpaid work. The association between ED pathologies and work participation and performance must be well understood to strengthen vocational rehabilitation programmes and prevent occupational disruptions in the ED population. The aims of this study are: (1) to examine the degree of association between ED pathologies and work participation and performance in 15-year-olds and older; (2) to highlight the specific ED symptoms that are most correlated with changes in work performance and participation; (3) to compile the most common metrics and assessments used to measure work participation and performance with ED. Methods Medline, Embase, CINAHL, Web of Science, PsycINFO, and Cochrane Library will be searched for observational and experimental studies that meet the following criteria: (1) a clinical sample of typical or atypical ED; (2) paid or unpaid employment or training; (3) an association between ED pathologies and work participation or performance. Unpublished data will also be examined. Title and abstract, and full-text screening will be conducted in duplicate. Risk of bias and quality of evidence assessments will be completed. A random-effect meta-analysis will be performed. Discussion This synthesis can clarify knowledge and gaps around the impact of ED on work functioning, thereby allowing better evaluation, improvements and development of current workplace assessments, interventions, and policies. Trial registration The registration number for this systematic review on PROSPERO is CRD42021255055.

scholarly journals Selected Properties of the Surface Layer of C45 Steel Parts Subjected to Laser Cutting and Ball Burnishing

Materials ◽  
2020 ◽  
Vol 13 (15) ◽  
pp. 3429 ◽  
Author(s):  
Agnieszka Skoczylas ◽  
Kazimierz Zaleski
Keyword(s):  
Surface Layer ◽  
Residual Stresses ◽  
Laser Cutting ◽  
Experimental Studies ◽  
Hardened Layer ◽  
Ball Burnishing ◽  
Absolute Value ◽  
The Impact ◽  
Compressive Residual Stresses

In this article, we report the results of experimental studies on the impact of ball burnishing parameters on the roughness, microstructure and microhardness of the surface layer of laser-cut C45 steel parts. We also analysed the distribution of residual stresses generated in the surface layer of these parts. Laser-cut parts often require finishing to improve the quality of their surface. The tests performed in this study were aimed at assessing whether ball burnishing could be used as a finishing operation for parts of this type. Ball burnishing tests were performed on an FV-580a vertical machining centre using a mechanically controlled burnishing tool. The following parameters were varied during the ball burnishing tests: burnishing force Fn, path interval fw and the diameter of the burnishing ball dn. Ball burnishing of laser-cut C45 steel parts reduced the surface roughness parameters Sa and Sz by up to 60% in relation to the values obtained after laser cutting. Finish machining also led to the reorganization of the geometric structure of the surface, resulting in an increase in the absolute value of skewness Ssk. This was accompanied by an increment in microhardness (maximum microhardness increment was ΔHV = 95 HV0.05, and the thickness of the hardened layer was gh = 40 µm) and formation of compressive residual stresses in the surface layer.

Impact on OS of 2nd and 3rd generation TKI in EGFR mt+ and ALK+ patients: Results of the NOWEL network.

2017 ◽  
Vol 35 (15_suppl) ◽  
pp. e20560-e20560 ◽  
Author(s):  
Julia Roeper ◽  
Maria Netchaeva ◽  
Anne Christina Lueers ◽  
Ursula Stropiep ◽  
Cora Hallas ◽  
...  
Keyword(s):  
Real Life ◽  
Stage Iv ◽  
Cancer Centers ◽  
Real Life Setting ◽  
Effective Choice ◽  
Detection Of Mutations ◽  
The Impact ◽  
Choice Of Therapy ◽  
Generation Sequencing

e20560 Background: Available clinical research data shows that early mutation testing for patients with NSCLC stage IV could lead to an effective choice of therapy for patients with proven mutations. Targeted therapies achieve a higher ORR, PFS, OS and a better quality of life than chemotherapy in mt+ patients. With the advent of 2nd and 3rd generation TKI´s effective in 1st generation TKI resistant tumors, we wanted to study the impact of these drugs on the outcome of patients in a real life setting in 3 lung cancer centers. Methods: 1383 patients from the three cancer centers diagnosed with NSCLC stage IV (UICC 7) were examined. Methods for the detection of mutations included Sanger Sequencing, hybridization based COBAS testing as well as hybrid cage next generation sequencing. Results: 880/1383 (64%) consecutive patients with non-squamous cell NSCLC from the cancer centers were studied for the presence of tumor mutations, especially for EGFR and ALK mutations. The EGFR mutation rate was 16.6% (141/880), and the ALK-translocation rate 3.8% (24/635). Median OS in EGFR mt+ patients was 31 (n = 78) vs. 32 (n = 38) vs. 16 (n = 14) months respectively (center 1 vs. center 2 vs. center 3). Median OS in ALK mt+ patients was 25 (n = 17) months in center 1 and 11 (n = 5) months in center 2 (p < 0.05). Use of 3rd generation TKI Osimertinib (n = 17) lead to a significantly higher OS (n = 17, median OS 67 mo) than the use of only 1st and 2nd generation TKI (n = 113, median OS 24 mo, p < 0.000). Similarly, use of 2nd and 3rd generation ALKi impacted significantly on median OS: Crizotinib alone n = 7, 17 months, Crizotinib followed by Ceritinib and/or Brigatinib (n = 9) median OS not reached, p < 0.001. Conclusions: Smalldifferences in OS were observed, depending on the treatment centers, but the use of multiple EGFR and ALK-I impacted highly significantly on the outcome of patients with EGFR and ALK-alterations in a real life setting.

scholarly journals IMPROVEMENT OF THE STRUCTURAL LAYOUT OF POTATO PLANTERS’ COULTER GROUP

2021 ◽  
pp. 81-90
Author(s):  
Alexey Semenovich Dorokhov ◽  
Andrey Grigoryevich Ponomarev ◽  
Vitaly Nikolaevich Zernov ◽  
Sergey Nikolaevich Petukhov ◽  
Alexander Gennadievich Aksenov ◽  
...  
Keyword(s):  
Experimental Studies ◽  
Acute Angle ◽  
Sharp Angle ◽  
Maximum Extent ◽  
Automatic Maintenance ◽  
Potato Planter ◽  
Growing Conditions ◽  
The Stability ◽  
The Impact

Structural layouts of coulters and their groups in potato planters are justified in the article based on the morphological features of the potato plant, its requirements for growing conditions and ensuring the quality of the planting process. The purpose of coulter groups is to form a bed for placing tubers with a loose layer of soil in 5-8 cm and sealing them with loosened soil to a certain depth. To substantiate the type of potato planter coulters that meet the requirements for potato growing conditions to the maximum extent possible, optimize the parameters of coulter groups that automatically ensure the stability of the coulter travel depth when imitating irregularities of the field microrelief. A comparative analysis of the impact on the soil of the most common anchor coulters with a blunt angle of soil entry and a sharp angle with an individual floating suspension is given, and indicators of the quality of their operation are described. It was found that coulters with an individual floating suspension and an acute angle of soil entry meet the requirements for potato growing conditions to the maximum extent possible. In order to ensure travel stabilization of such a coulter at a given depth when imitating field irregularities, a version of the coulter group has been developed that provides automatic correction of the coulter's angle of attack when changing its travel depth. Experimental studies have optimized the parameters of the coulter suspension that ensure automatic imitation of field microrelief irregularities up to 20 cm deep within the initial requirements for potato planting machines. Coulters with an individual floating suspension and a sharp angle of soil entry most fully meet the requirements for potato growing conditions to the maximum extent possible. A coulter group with a suspension aspect ratio of 150:200:400:400 cm and an acute angle of coulter entry into the soil provides automatic maintenance of the set coulter travel depth within the initial requirements (±2 cm) for irregularities in the field microrelief of up to 200 mm. In this case, the bottom and walls of the furrow are not compacted.

scholarly journals The Impact of Social Cognition on the Real-Life of People with Epilepsy

2021 ◽  
Vol 11 (7) ◽  
pp. 877
Author(s):  
Arminas Jasionis ◽  
Kristijonas Puteikis ◽  
Rūta Mameniškienė
Keyword(s):  
Social Cognition ◽  
Interpersonal Relationships ◽  
Real Life ◽  
Life Outcomes ◽  
Level Of Education ◽  
The Mind ◽  
Patients With Epilepsy ◽  
The Impact ◽  
Strange Stories Test

Background. Previous research has demonstrated the impairment of social cognition (SC) in people with epilepsy. It is associated with worse social functioning and quality of life; however, the influence on real-life outcomes is unknown. The purpose of this study was to investigate how SC is associated with epilepsy variables and real-life outcomes (education, employment and relationships) among patients with epilepsy (PWE). Methods. Eighty-one PWE completed tasks of theory of mind (ToM) (faux pas recognition (FPRT) and Happé Strange Stories test (HST)) and emotion recognition (ER) (Reading of the Mind in the Eyes (RMET)). Variables reflecting their education, employment and relationship status were treated as endpoints in search of association with SC. Data from a matched group (n = 30) of healthy controls (HCs) were used for comparison of ToM abilities. Results. ToM scores were lower among PWE as compared to HCs (U = 1816.0, p < 0.0001 (HST), U = 1564.5, p = 0.020 (FPRT)). All SC tests were associated with the level of education (OR = 1.22, 95% confidence interval (CI) = 1.09 to 1.36 (RMET), OR = 1.20, 95% CI = 1.02 to 1.40 (HST), OR = 0.93, 95% CI = 0.87 to 1.00 (FPRT)). The results of ToM and ER testing were not associated with employment (χ2 = 33.423, p < 0.0001) if adjusted for the level of education (B = 0.804, OR = 2.23 (95% CI = 1.33 to 3.76), p = 0.002). SC abilities did not differ between PWE who were single and those in a relationship (U = 858.5, p = 0.541 (HST)), t= −1.236, p = 0.220 (RMET), U = 909.5, p = 0.271 (FPRT)). Conclusion. Better social cognition skills are linked to a higher level of education among PWE. SC probably has less influence on professional achievements and interpersonal relationships.

Approaches to Measuring the Impact of Music Therapy and Music Activities on People Living With Dementia

2019 ◽  
pp. 171-196
Author(s):  
Becky Dowson ◽  
Orii McDermott
Keyword(s):  
Music Therapy ◽  
Outcome Measures ◽  
Quantitative Research ◽  
Psychological Symptoms ◽  
Real Life ◽  
Evidence Base ◽  
People With Dementia ◽  
The Impact ◽  
Music Activities

This chapter provides an introduction to the evaluation of music activities and music therapy for people with dementia. We outline some of the main challenges and considerations involved in choosing or using outcome measures. An overview of common outcome measures used in current research, including those for behavioral and psychological symptoms, quality of life, physiological changes, cognitive function, and music-related behaviors, is provided. Two music-therapy case studies are presented as real-life examples of how to select clinically relevant measures. Clinicians have long argued that some clinically meaningful changes may not always be measurable. We propose that when insights obtained from high-quality qualitative and mixed methods studies are added to the evidence base of quantitative research, it will lead to a deeper understanding of the benefits that music can have in the lives of people living with dementia.

scholarly journals Observed Quality of Formative Peer and Self-Assessment in Everyday Mathematics Teaching and its Effects on Student Performance

2022 ◽  
Vol 11 (2) ◽  
pp. 663-680
Author(s):  
Sandra Zulliger ◽  
Alois Buholzer ◽  
Merle Ruelmann
Keyword(s):  
Student Performance ◽  
Mathematics Teaching ◽  
Performance Test ◽  
Peer Assessment ◽  
Experimental Studies ◽  
Real Life ◽  
General Effect ◽  
Everyday Mathematics ◽  
Self Assessment

<p style="text-align: justify;">The positive effect of peer assessment and self-assessment strategies on learners' performance has been widely confirmed in experimental or quasi-experimental studies. However, whether peer and self-assessment within everyday mathematics teaching affect student learning and achievement, has rarely been studied. This study aimed to determine with what quality peer and self-assessment occur in everyday mathematics instruction and whether and which students benefit from it in terms of achievement and the learning process. Two lessons on division were video-recorded and rated to determine the quality of peer and self-assessment. Six hundred thirty-four students of fourth-grade primary school classes in German-speaking Switzerland participated in the study and completed a performance test on division. Multilevel analyses showed no general effect of the quality of peer or self-assessment on performance. However, high-quality self-assessment was beneficial for lower-performing students, who used a larger repertoire of calculation strategies, which helped them perform better. In conclusion, peer and self-assessment in real-life settings only have a small effect on the student performance in this Swiss study.</p>

scholarly journals Comparing COVID-19 vaccines for their characteristics, efficacy and effectiveness against SARS-CoV-2 and variants of concern

2021 ◽  
Author(s):  
Fiolet ◽  
Yousra Kherabi ◽  
Conor MacDonald ◽  
Jade Ghosn ◽  
Nathan Peiffer-Smadja
Keyword(s):  
South Africa ◽  
Herd Immunity ◽  
Real Life ◽  
Cost Effective ◽  
Phase Iii ◽  
Real Life Data ◽  
National Drug ◽  
Phase Iii Trials ◽  
The Impact

Vaccines are critical cost-effective tools to control the COVID-19 pandemic. However, the emergence of more transmissible SARS-CoV-2 variants may threaten the potential herd immunity sought from mass vaccination campaigns.The objective of this study was to provide an up-to-date comparative analysis of the characteristics, adverse events, efficacy, effectiveness and impact of the variants of concern (Alpha, Beta, Gamma and Delta) for fourteen currently authorized COVID-19 vaccines (BNT16b2, mRNA-1273, AZD1222, Ad26.COV2.S, Sputnik V, NVX-CoV2373, Ad5-nCoV, CoronaVac, BBIBP-CorV, COVAXIN, Wuhan Sinopharm vaccine, QazCovid-In, Abdala and ZF200) and two vaccines (CVnCoV and NVX-CoV2373) currently in rolling review in several national drug agencies.Overall, all COVID-19 vaccines had a high efficacy against the traditional strain and the variants of SARS-CoV-2, and were well tolerated. BNT162b2, mRNA-1273 and Sputnik V had the highest efficacy (&gt;90%) after two doses at preventing symptomatic cases in phase III trials. Efficacy was ranging from 10.4% for AZD1222 in South Africa to 50% for NVX-CoV2373 in South Africa and 50 % for CoronaVac in Brazil, where the 501YV.2 and P1 variants were dominant. Seroneutralization studies showed a negligible reduction in neutralization activity against Alpha for most of vaccines, whereas the impact was modest for Delta. Beta and Gamma exhibited a greater reduction in neutralizing activity for mRNA vaccines, Sputnik V and CoronaVac. Regarding observational real-life data, most studies concerned the Pfizer and Moderna vaccines. Full immunization with mRNA vaccines effectively prevents SARS-CoV-2 infection against Alpha and Beta. All vaccines appeared to be safe and effective tools to prevent symptomatic and severe COVID-19, hospitalization and death against all variants of concern, but the quality of evidence greatly varied depending on the vaccines considered. There are remaining questions regarding specific populations excluded from trials, the duration of immunity and heterologous vaccination. Serious adverse event and particularly anaphylaxis (2.5-4.7 cases per million doses among adults) and myocarditis (3.5 cases per million) for mRNA vaccines ; thrombosis with thrombocytopenia syndrome for Janssen vaccine (3 cases per million) and AstraZeneca vaccine (2 cases per million) and Guillain-Barre syndrome (7.8 cases per million) for Janssen vaccine are very rare. COVID-19 vaccine benefits outweigh risks, despite rare serious adverse effect.

scholarly journals Thermal bridges in building envelopes – An overview of impacts and solutions

2018 ◽  
Vol 9 (1) ◽  
pp. 31-40 ◽  
Author(s):  
A. Alhawari ◽  
P. Mukhopadhyaya
Keyword(s):  
Experimental Studies ◽  
Building Energy ◽  
Energy Performance ◽  
Building Energy Efficiency ◽  
Thermal Bridge ◽  
Thermal Bridges ◽  
Thermal Bridging ◽  
Negative Impacts ◽  
The Impact

Increasing building energy performance has become an obligatory objective in many countries. Thermal bridge is a major cause of poor energy performance, durability, and indoor air quality of buildings. This paper starts with a review of thermal bridges and their negative impacts on building energy efficiency. Based on published literatures, various types of building thermal bridges are discussed in this paper, including the most effective solutions to diminish their impacts. In addition, various numerical and experimental studies on the balcony thermal bridge are explored. Results show that among all types of thermal bridges, the exposed balcony slab produces the most challenging thermal bridging problem where an integrated thermal and structural design is required. Using low thermal conductivity materials in building construction could help in reducing the impact of thermal bridges. Finally, further investigations are needed to develop more innovative and effective solutions for the balcony thermal bridge.

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