Characteristics of dental hard tissues in chronic kidney disease: morphology, chemical composition, possibilities of remineralizing therapy

Stomatologiya ◽  
2019 ◽  
Vol 98 (3) ◽  
pp. 25
Author(s):  
A. K. Iordanishvili ◽  
O. A. Belskikh ◽  
O. L. Pikhur
2011 ◽  
Vol 36 (5) ◽  
pp. 529-536 ◽  
Author(s):  
FY Cakir ◽  
Y Korkmaz ◽  
E Firat ◽  
SS Oztas ◽  
S Gurgan

SUMMARY Purpose To determine the change in the chemical composition of enamel and dentin as well as to evaluate the differences in surface texture of the same dental hard tissues following three at-home bleaching systems in vitro. Methods Sixty extracted intact human anterior teeth were used in this study. Thirty teeth were used as samples for enamel, and the buccal surfaces of the remaining 30 teeth were abraded and used as dentin samples. Prior to bleaching treatments, calcium (Ca), phosphorus (P), potassium (K), sodium (Na), magnesium (Mg), fluoride (F), and oxygen (O) levels of each sample were measured using an energy dispersive spectrometer. The teeth were then randomly allocated into three groups according to the bleaching system used, as follows: GI, 10% carbamide peroxide (CP); GII, 20% CP; GIII, and 35% CP. Following the bleaching treatments, Ca, P, K, Na, Mg, F, and O measurements were repeated. The surface configurations were examined using scanning electron microscopy (SEM). The data were analyzed using Wilcoxon signed rank and Kruskal-Wallis tests followed by the Dunn test. Results All three bleaching systems tested caused similar changes in the chemical composition of enamel and dentin. Bleaching systems decreased Ca and K, while F and O levels increased in enamel. In dentin, Ca, P, and K levels decreased; however, Na, F, and O levels increased. SEM observations revealed no deleterious effect on enamel and dentin. Conclusion The use of home bleaching agents could affect the chemical composition of dental hard tissues, whereas the change in the chemical composition of enamel and dentin was not affected by the CP concentration of the bleaching systems used.


Author(s):  
Morozova N.S. ◽  
Elovskaya A.A.

Urological diseases are one of the reasons that lead to reduced quality of life, disability and premature mortality and create a number of socially significant issues. In the last two decades it was observed that intensive development in methods of diagnostics and treatment of renal diseases in pediatric nephrology has led to decrease of mortality level among patients. Therefore, the number of children with these pathologies has risen in dental practice. Children suffering from chronic kidney disease require particular attention from dentists. This is due to renal disturbance has a negative effect on dentoalveolar system. It can be manifested as structural jawbone changes, temporomandibular joint function disturbance, periodontal and oral mucosal diseases, salivary composition, quality, quantity and consistency characteristics changes, dental hard tissues defects, pulp calcification due to urological diseases. In this regard, it is highly important to exclude pathological focus in oral cavity in this group of patients. Based on this, such patients need specialized dental care. However, the lack of a systematic approach and understanding of the mechanisms of the dentoalveolar anomalies occurrence of patients with chronic kidney disease limits dentists in correct differential diagnosis and prevention of dental disease complications against the background of underlying disease. That is why the aim of this article - to inform dentists about full spectrum of dentoalveolar system changes in children and adolescents with chronic kidney disease.


Bone ◽  
2011 ◽  
Vol 48 (6) ◽  
pp. 1260-1267 ◽  
Author(s):  
Yoshiko Iwasaki ◽  
Junichiro James Kazama ◽  
Hideyuki Yamato ◽  
Masafumi Fukagawa

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Liza K. McDonough ◽  
Karina T. Meredith ◽  
Chandima Nikagolla ◽  
Ryan J. Middleton ◽  
Jian K. Tan ◽  
...  

Abstract Chronic kidney disease (CKD) of unknown etiology (CKDu) mostly affects agricultural communities in Central America, South Asia, Africa, but likely also in North America and Australia. One such area with increased CKDu prevalence is the Medawachchiya District Secretariat Division of the Anuradhapura District in the North Central Province of Sri Lanka. Recent research has focused on the presence of various microbial pathogens in drinking water as potential causal or contributing factors to CKDu, yet no study to date has performed a more comprehensive microbial and water chemistry assessment of household wells used for domestic water supply in areas of high CKDu prevalence. In this study, we describe the chemical composition and total microbial content in 30 domestic household wells in the Medawachchiya District Secretariat Division. While the chemical composition in the tested wells mostly lies within standard drinking water limits, except for high levels of fluoride (F), magnesium (Mg), sodium (Na), chloride (Cl) and calcium (Ca) in some samples, we find a frequent presence of cyanotoxin-producing Microcystis, confirming earlier studies in Sri Lanka. Since the total microbial content of drinking water also directly influences the composition of the human gut microbiome, it can be considered an important determinant of health. Several bacterial phyla were previously reported in the gut microbiome of patients with CKD. Using these bacteria phyla to define operational taxonomic units, we found that these bacteria also occur in the microbiome of the sampled well water. Based on available environmental data, our study demonstrates associations between the abundances of these bacteria with geographical distribution, well water temperature and likely fertilizer use in the local surface water catchment area of the individual household wells. Our results reinforce the recommendation that household wells with stagnant or infrequently used water should be purged prior to use for drinking water, bathing and irrigation. The latter is suggested because of the reported potential accumulation of bacterial toxins by agricultural crops. The observation that bacteria previously found in chronic kidney disease patients are also present in household wells requires a more detailed systematic study of both the human gut and drinking water microbiomes in CKDu patients, in relation to disease prevalence and progression.


Sign in / Sign up

Export Citation Format

Share Document