Glycemic Control and Awareness of Insulin Therapy

Introduction: Glycemic control is associated with better health outcomes among patients with diabetes. No previous research has examined the relationship between knowledge of one’s insulin dose and glycemic control. This study sought to determine if patients who accurately recalled their insulin dose achieved better glycemic control than patients who could not remember their dose. Methods: Interviews were conducted with 106 patients. Data were collected during patients’ appointments at two endocrinology clinics in Wichita, Kansas from May 29, 2018 to February 15, 2019. Adequate glycemic control was defined as an HbA1c of less than 7.5%. A multiple logistic regression model was developed to identify factors associated with glycemic control. Results: Of the 109 patients asked to participate, 105 agreed to participate in the study. About half (45%, n = 48) were male. Patients’ mean age was 50 years (SD = 17). Seventy-seven percent (n = 81) were overweight (body mass index (BMI) of 25 to 29.9) or obese (BMI >30). Patients who correctly stated their insulin dose had a mean Hemoglobin A1c (HbA1c) of 6.9% (SD = 0.98), whereas those who incorrectly stated their dose had a mean HbA1c of 9.5% (SD = 1.9; p <0.0001). Conclusions: There was a significant relationship between knowledge of one’s insulin dose and adequate glycemic control.

Download Full-text

Risk Factors Associated With Hyperuricemia in Patients with Diabetes Type 2: About 190 Cases

10.36502/2020/droa.6163 ◽

2020 ◽

Vol 2 (1) ◽

pp. 12-16

Author(s):

Fennoun H ◽

Haraj NE ◽

El Aziz S ◽

Bensbaa S ◽

Chadli A

Keyword(s):

Type 2 Diabetes ◽

Heart Disease ◽

Glycemic Control ◽

Ischemic Heart Disease ◽

Diabetes Type 2 ◽

Diabetes Type ◽

Ischemic Heart ◽

Factors Associated ◽

Patients With Diabetes

Introduction: Hyperuricemia is common Type 2 diabetes at very high cardiovascular risk. Objective: Evaluate the relationship between hyperuricemia and diabetes type 2, and determine its predictive factors in this population. Patients and Methods: Retrospective study cross including 190 patients with diabetes type 2 hospitalized Service of Endocrinology of CHU Ibn Rushd Casablanca from January 2015 to December 2017. Hyperuricemia was defined as a serum uric acid concentration> 70 mg/L (men) and> 60 mg/L (women). The variables studied were the anthropometric measurements), cardiovascular factors (tobacco, hypertension, dyslipidemia), and degenerative complications (retinopathy, neuropathy, kidney failure, ischemic heart disease). The analyzes were performed by SPSS software. Results: Hyperuricemia was found in 26.5% of patients with a female predominance (76%), an average age of 55.9 years, and an average age of 12.4ans diabetes. The glycemic control was found in 84.6% of cases with mean glycated hemoglobin 8.6%. Factors associated al hyperuricemia were the blood pressure in 86% (p <0.05), dyslipidemia in 76.3% of cases (p <0.001) with hypertriglyceridemia in 48.3% of cases (p <0.02), and a hypoHDLémie 28% (p <0.001). The age, obesity, smoking, and glycemic control were associated significantly n al hyperuricemia. The research of degenerative complications of hyperuricemia has objectified renal impairment (GFR between 15 and 60ml / min) chez47% (p <0.001), it was kind of moderate in 35.8% (p <0.01) and severe in 5.1% (p <0.02), ischemic heart disease was found in 34% of cases (p <0.01). Conclusion: In our study, hyperuricemia in type 2 diabetes is common in female patients, especially with hypertension, dyslipidemia, and renal failure. Other factors such as age, obesity, smoking is not associated with hyperuricemia in type 2 diabetics.

Download Full-text

Prevalence and Factors Associated with Hypertension among Adolescents in Malaysia

IIUM Medical Journal Malaysia ◽

10.31436/imjm.v18i1.225 ◽

2020 ◽

Vol 18 (1) ◽

Author(s):

Liew JK ◽

Cheong XP ◽

Law L ◽

Teo WH ◽

Eng SS ◽

...

Keyword(s):

Blood Pressure ◽

Body Mass Index ◽

Body Weight ◽

Statistical Analysis ◽

Strong Association ◽

Lifestyle Factors ◽

Factors Associated ◽

High Prevalence ◽

The Relationship ◽

Malaysian Adolescents

Introduction: Evidence has shown an increase in paediatric hypertension globally and this could give rise to increase prevalence of adult hypertension. The purpose of this paper was to determine the prevalence of hypertension among adolescents in Malaysia as well as the association between hypertension and lifestyle factors selected based on published literature. Methods: Adolescents aged 13-17 years old were selected randomly from two secondary schools to have their blood pressure measured. Their lifestyle information was obtained through completed bilingual questionnaires based on validated instruments, as well as anthropometry measurements. The relationship between hypertension and lifestyle factors was determined through statistical analysis. Results: A total of 273 students were included in the study with 120 (44%) males and 153 (56%) females. The prevalence of hypertension was 24.5% among the respondents with the highest being recorded among Malays (28.7%). Generally, hypertension was associated with an increased Body Mass Index (BMI) (AOR=4.053, 95%CI=1.677-9.795, p=0.002) and waist circumference (WC) (AOR=2.918, 95%CI=1.171-7.269, p=0.021) in all respondents. Similar associations were noted in females (BMI: AOR=7.707, 95%CI=2.043-29.072, p=0.003; WC: AOR=3.690, 95%CI=1.011-13.464, p=0.048) but not in males. Conclusion: Hypertension recorded high prevalence among Malaysian adolescents in our study. The strong association between elevated body weight, BMI and WC with hypertension may require further study to evaluate the need for screening

Download Full-text

Partial remission in children and adolescents with type 1 diabetes: an analysis based on the insulin dose-adjusted hemoglobin A1c

Journal of Pediatric Endocrinology and Metabolism ◽

10.1515/jpem-2021-0048 ◽

2021 ◽

Vol 0 (0) ◽

Author(s):

Emine Ayça Cimbek ◽

Aydın Bozkır ◽

Deniz Usta ◽

Nazım Ercüment Beyhun ◽

Ayşenur Ökten ◽

...

Keyword(s):

Type 1 Diabetes ◽

Partial Remission ◽

Hemoglobin A1c ◽

Insulin Dose ◽

Age At Onset ◽

Insulin Requirement ◽

C Peptide ◽

Factors Associated ◽

Daily Insulin

Abstract Objectives Most patients with type 1 diabetes (T1D) experience a transient phase of partial remission (PR). This study aimed to identify the demographic and clinical factors associated with PR. Methods This was a longitudinal retrospective cohort study of 133 children and adolescents with T1D. PR was defined by the gold standard insulin dose-adjusted hemoglobin A1c (HbA1c) (IDAA1c) of ≤9. Results Remission was observed in 77 (57.9%) patients. At diagnosis, remitters had significantly higher pH (7.3 ± 0.12 vs. 7.23 ± 0.15, p=0.003), higher C-peptide levels (0.45 ± 0.31 ng/mL vs. 0.3 ± 0.22, p=0.003), and they were significantly older (9.3 ± 3.6 years vs. 7.3 ± 4.2, p=0.008) compared with non-remitters. PR developed more frequently in patients without diabetic ketoacidosis (DKA) (p=0.026) and with disease onset after age 5 (p=0.001). Patients using multiple daily insulin regimen were more likely to experience PR than those treated with a twice daily regimen (63.9 vs. 32%, p=0.004). Only age at onset was an independent predictor of PR (OR: 1.12, 95% CI: 1-1.25; p=0.044). Remitters had lower HbA1c levels and daily insulin requirement from diagnosis until one year after diagnosis (p<0.001). PR recurred in 7 (9%) patients. The daily insulin requirement at three months was lower in remitters with PR recurrence compared to those without (0.23 ± 0.14 vs. 0.4 ± 0.17 U/kg/day, p=0.014). Conclusions Addressing factors associated with the occurrence of PR could provide a better comprehension of metabolic control in T1D. The lack of DKA and higher C-peptide levels may influence PR, but the main factor associated with PR presence was older age at onset. PR may recur in a small proportion of patients.

Download Full-text

Racial Variation in the Relationship of Glycemic Control with Fracture Risk in Elderly Patients with Diabetes

Diabetes Metabolic Syndrome and Obesity Targets and Therapy ◽

10.2147/dmso.s272076 ◽

2020 ◽

Vol Volume 13 ◽

pp. 4153-4155

Author(s):

M Kathleen Figaro ◽

Dustin M Long ◽

Michael E May ◽

Harrison Ndetan ◽

Alan Cook ◽

...

Keyword(s):

Glycemic Control ◽

Elderly Patients ◽

Fracture Risk ◽

Racial Variation ◽

Patients With Diabetes ◽

Relationship Of ◽

The Relationship

Download Full-text

evaluating the relationship between body mass index (BMI) and health-related quality of life (HRQoL) of patients With diabetes

Value in Health ◽

10.1016/j.jval.2014.03.1495 ◽

2014 ◽

Vol 17 (3) ◽

pp. A256-A257 ◽

Cited By ~ 1

Author(s):

A. Adeyemi ◽

K.L. Rascati ◽

K.A. Lawson ◽

J.C. Barner ◽

J. Wilson ◽

...

Keyword(s):

Quality Of Life ◽

Body Mass Index ◽

Body Mass ◽

Health Related Quality ◽

Patients With Diabetes ◽

Related Quality ◽

Health Related ◽

The Relationship

Download Full-text

Factors Associated with Glycemic Control and Diabetes-Related Costs in Patients with Diabetes in the United Arab Emirates: Results From A Retrospective Large Claims Data Analysis

Value in Health ◽

10.1016/j.jval.2016.08.210 ◽

2016 ◽

Vol 19 (7) ◽

pp. A897

Author(s):

YC CHOI ◽

YJ Lee ◽

SH Lee ◽

C Chang ◽

I Song ◽

...

Keyword(s):

Data Analysis ◽

Glycemic Control ◽

United Arab Emirates ◽

Claims Data ◽

Factors Associated ◽

Patients With Diabetes ◽

Claims Data Analysis

Download Full-text

The relationship of regional hemoglobin A1c testing and amputation rate among patients with diabetes

Vascular ◽

10.1177/1708538116650099 ◽

2016 ◽

Vol 25 (2) ◽

pp. 142-148

Author(s):

Karina A Newhall ◽

Kimon Bekelis ◽

Bjoern D Suckow ◽

Daniel J Gottlieb ◽

Adrienne E Farber ◽

...

Keyword(s):

Lower Extremity ◽

Hemoglobin A1c ◽

Lower Extremity Amputation ◽

Amputation Rate ◽

The Past ◽

Hospital Referral ◽

Patients With Diabetes ◽

Leg Amputation ◽

The Relationship ◽

Extremity Amputation

Objective The risk of leg amputation among patients with diabetes has declined over the past decade, while use of preventative measures—such as hemoglobin A1c monitoring—has increased. However, the relationship between hemoglobin A1c testing and amputation risk remains unclear. Methods We examined annual rates of hemoglobin A1c testing and major leg amputation among Medicare patients with diabetes from 2003 to 2012 across 306 hospital referral regions. We created linear regression models to study associations between hemoglobin A1c testing and lower extremity amputation. Results From 2003 to 2012, the proportion of patients who received hemoglobin A1c testing increased 10% (74% to 84%), while their rate of lower extremity amputation decreased 50% (430 to 232/100,000 beneficiaries). Regional hemoglobin A1c testing weakly correlated with crude amputation rate in both years (2003 R = −0.20, 2012 R = −0.21), and further weakened with adjustment for age, sex, and disability status (2003 R = −0.11, 2012 R = −0.17). In a multivariable model of 2012 amputation rates, hemoglobin A1c testing was not a significant predictor. Conclusion Lower extremity amputation among patients with diabetes nearly halved over the past decade but only weakly correlated with hemoglobin A1c testing throughout the study period. Better metrics are needed to understand the relationship between preventative care and amputation.

Download Full-text