scholarly journals Kinetics of neomycin release from polylactide spheres and its antimicrobial activity

2021 ◽  
Vol 51 (1) ◽  
pp. 0-0
Author(s):  
Agnieszka Gadomska-Gajadhur ◽  
Paweł Ruśkowski ◽  
Aleksandra Kruk ◽  
Jolanta Mierzejewska
Keyword(s):  
Antimicrobial Activity ◽  
Kinetics Of

scholarly journals Antimicrobial activity and time kill kinetics of Nigerian Honeys on multi-resistant Enteric Bacilli

2018 ◽  
Vol 210 ◽  
pp. 012003
Author(s):  
P.A Akinduti ◽  
A Oluwadun ◽  
J.A.O Olugbuyiro ◽  
C.S Osuagwu ◽  
O Ejilude ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Time Kill ◽  
Kinetics Of

Kinetics of antimicrobial activity of aztreonam/clavulanic acid (2:1) against Xanthomonas maltophilia

1991 ◽  
Vol 27 (4) ◽  
pp. 552-554 ◽  
Author(s):  
J. A. GARCÍA-RODRÍGUEZ ◽  
J. E. GARCÍA SÁNCHEZ ◽  
J. L. MUÑOZ BELLIDO ◽  
M. I. GARCÍA GARCÍA ◽  
E. GARCÍA SANCHEZ
Keyword(s):  
Antimicrobial Activity ◽  
Clavulanic Acid ◽  
Xanthomonas Maltophilia ◽  
Kinetics Of

scholarly journals Synthesis and Characterization of Gellan Gum-Pyridoxine Nanoparticle for Treatment of Localized Peripheral Neuropathy

2019 ◽  
Vol 9 (1S4) ◽  
pp. 576-580
Keyword(s):  
Antimicrobial Activity ◽  
Peripheral Neuropathy ◽  
Release Kinetics ◽  
Drug Carrier ◽  
Gellan Gum ◽  
Synthesis And Characterization ◽  
Antioxidant Assay ◽  
Gram Positive Bacteria ◽  
Kinetics Of

Biopolymer has full application as a drug carrier and scaffold in tissue engineering because of its biodegradability and non-toxicity. The present study is focused on novel biopolymer gellan gum as a drug delivery agent. The objective of the study is to synthesize the gellan gum nanoparticle by solvent evaporation emulsification method and characterize it using SEM, DLS, FTIR, and XRD. As pyridoxine is effectively used to treat diabetic peripheral neuropathy, it has been encapsulated with gellan gum and characterized. The antioxidant assay was performed using ABTS reagent, and the activity increases with increasing concentration of nanoparticle. Also, it has significant antimicrobial activity against gram-positive bacteria. Apart from this, the drug release kinetics of the gellan gum- pyridoxine nanoparticle was studied.

scholarly journals Activated carbon from termite feces impregnated with silver: Preparation and evaluation of antimicrobial activity and ecotoxicity

2020 ◽  
Vol 17 (2) ◽  
pp. 1-24
Author(s):  
Giovanna Manesco ◽  
Carla Albertina Demarchi ◽  
Alexandre Bella Cruz ◽  
Jean Felipe Fossá Calisto ◽  
Rafael Martello ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Microbial Growth ◽  
Inhibitory Concentration ◽  
Chlorophyll Synthesis ◽  
Artemia Salina ◽  
Water Disinfection ◽  
E Coli ◽  
Seedling Germination ◽  
Kinetics Of ◽  
Preparation And Evaluation

Silver has a potent antimicrobial action, but its use is still restricted due to toxicity and aggregation problems. Impregnation with active carbon (AC) has been suggested as an alternative to solve this problem. In this study, termite feces were used to prepare composites containing silver nanoparticles and AC. Reducing agents and different amounts of H2 SO4 and silver were used. Antimicrobial activity was assessed using the minimum inhibitory concentration (MIC) and the kinetics of microbial growth of S. aureus, E. coli and C. albicans. Phytotoxicity and acute toxicity were assessed for Cucumis sativus and Artemia salina. The composites that presented MIC 500 μg/mL for S. aureus and E. coli were AC25Ag (6 μg/mL Ag) and AC25AgB (78 μg/mL Ag), respectively. AC6AgS showed antimicrobial activity in C. albicans with MIC of 500 μg/mL (23 μg/mL Ag). AC25AgB inhibited the growth of S. aureus and E. coli for 48 and 32 h, respectively. At a concentration of 10 g/L, the compounds showed deleterious effects on seedling germination and elongation and on the chlorophyll synthesis of C. sativus. The composites showed no toxicity to A. salina. Based on these results, AC25AgB has the potential to be used in water disinfection.

scholarly journals Antimicrobial and time-kill kinetics of the aqueous extract of Citrullus lanatus (Thunb.) seeds

Bio-Research ◽  
2020 ◽  
Vol 18 (1) ◽  
pp. 1103-1110
Author(s):  
UF Babaiwa ◽  
SO Eraga ◽  
JO Akerele
Keyword(s):  
Antimicrobial Activity ◽  
Aqueous Extract ◽  
Citrullus Lanatus ◽  
Antimicrobial Property ◽  
Inhibition Zone ◽  
Bacterial Strains ◽  
Microbiological Methods ◽  
Microbial Infections ◽  
Time Kill ◽  
Kinetics Of

This study evaluated the antimicrobial property of the aqueous extract of Citrullus lanatus (watermelon) seeds and its concentration-effect relationship (time-kill studies) on typed bacterial and fungal strains. Crude powdered seeds of Citrullus lanatus were extracted by maceration with water. Antimicrobial assay of the aqueous extracts was determined against Bacillus subtilis (NCTC 8236), Escherichia coli (ATCC 25922), Pseudomonas aeruginosa (ATCC 10145), Staphylococcus aureus (ATCC 25923), and Candida albicans (ATCC 24433) using standard microbiological methods. A total of 106 CFU/mL of each test strain was used as a baseline to carry out the time-kill studies. Extract concentration at minimum inhibitory concentration (MIC), 2MIC and 4MIC were used over a period of 24 hours. Aqueous extract had an intermediate antibacterial activity with inhibition zone diameters (IZD) of 15 - 18 mm and MIC range of 2.5 - 20 mg/mL. Time-kill studies showed a bacteriostatic, non-concentration dependent mode of antimicrobial activity with characteristic regrowth for all test strains. Citrullus lanatus seeds aqueous extract exhibited antimicrobial activity with a bacteriostatic, non-concentration dependent mode of action against test bacterial strains. Further studies aimed at isolating and purifying the antimicrobial principle in the aqueous extract of C. lanatus seed is warranted as this could serve as a potential new antibiotic for treating microbial infections.

scholarly journals Studies on Antimicrobial Activity and Kinetics of Inhibition by Plant Products in India (1990–2016)

2018 ◽  
Vol 101 (4) ◽  
pp. 948-955
Author(s):  
Ramesh Kumar Sharma ◽  
Bhupendra Kumar Rana
Keyword(s):  
Antimicrobial Activity ◽  
Antimicrobial Susceptibility ◽  
Antimicrobial Agents ◽  
Herbal Extracts ◽  
Analytical Approaches ◽  
Kinetics Of ◽  
Kinetics Of Inhibition ◽  
Regression Correlation

Abstract The antimicrobial activity of herbal extracts or plant isolates has usually been evaluated in India using different antimicrobial susceptibility testing methods generally based on diffusion and dilution. There are different analytical approaches for the reliable evaluation of antimicrobial activity ascribed to medicinal plants against selected pathogenic microorganisms. Obtained results may provide scientific bases for the selective use of these natural plants as healing drugs, crop-protecting pesticides, or shelf-life-extending solutions. In general, antimicrobial susceptibility methodologies involve in vivo and in vitro studies; at present, the in vitro evaluation of antibacterial activity appears more popular. Diffusion methods have some limitations, although they are extensively used to determine the susceptibility of organisms isolated from specimen samples to applied antimicrobials and vice versa. Dilution methods are preferred in the case of more precise antimicrobial activity estimation, in terms of minimum inhibitory concentration. With regard to the inherent antimicrobial nature of herbal compositions, herbs, and herbal extracts, Indian researchers have evaluated the reliability of these antimicrobial agents against selected pathogens and have shown them to be effective. Researchers have also tried to establish linear regression correlation analyses on the basis of available inhibition results. This research is still evolving, and interesting results may be expected in the future.

scholarly journals Antimicrobial Activities and Time-Kill Kinetics of Extracts of Selected Ghanaian Mushrooms

2017 ◽  
Vol 2017 ◽  
pp. 1-15 ◽  
Author(s):  
Theresa Appiah ◽  
Yaw Duah Boakye ◽  
Christian Agyare
Keyword(s):  
Antimicrobial Activity ◽  
Antimicrobial Agents ◽  
Schizophyllum Commune ◽  
Antimicrobial Properties ◽  
Antimicrobial Activities ◽  
Methanol Extracts ◽  
Test Organisms ◽  
Antibacterial And Antifungal ◽  
Time Kill ◽  
Kinetics Of

The rapid rise of antimicrobial resistance is a worldwide problem. This has necessitated the need to search for new antimicrobial agents. Mushrooms are rich sources of potential antimicrobial agents. This study investigated the antimicrobial properties of methanol extracts of Trametes gibbosa, Trametes elegans, Schizophyllum commune, and Volvariella volvacea. Agar well diffusion, broth microdilution, and time-kill kinetic assays were used to determine the antimicrobial activity of the extracts against selected test organisms. Preliminary mycochemical screening revealed the presence of tannins, flavonoids, triterpenoids, anthraquinones, and alkaloids in the extracts. Methanol extracts of T. gibbosa, T. elegans, S. commune, and V. volvacea showed mean zone of growth inhibition of 10.00±0.0 to 21.50±0.84, 10.00±0.0 to 22.00±1.10, 9.00±0.63 to 21.83±1.17, and 12.00±0.0 to 21.17±1.00 mm, respectively. The minimum inhibitory concentration of methanol extracts of T. gibbosa, T. elegans, S. commune, and V. volvacea ranged from 4.0 to 20, 6.0 to 30.0, 8.0 to 10.0, and 6.0 to 20.0 mg/mL, respectively. Time-kill kinetics studies showed that the extracts possess bacteriostatic action. Methanol extracts of T. gibbosa, T. elegans, S. commune, and V. volvacea exhibited antimicrobial activity and may contain bioactive compounds which may serve as potential antibacterial and antifungal agents.

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