scholarly journals Acute Lymphocytic Leukemia of Periorbital Tissue Presenting with Cluster-Like Headache

2020 ◽  
Vol 38 (2) ◽  
pp. 120-123
Author(s):  
Daye Yoon ◽  
Jeong Yeon Kim ◽  
Dae-Hyun Kim

Secondary cluster-like headache has been reported in association with various underlying diseases. A 20-year-old man came with right-sided headache that started 1 month ago. Initially, his headache was compatible with diagnostic criteria of episodic cluster headache. Magnetic resonance imaging showed multiple enhancement lesions in right frontal bone and periorbital area. With bone marrow biopsy, we confirmed that B-lymphoblastic leukemia relapsed. We describe an unusual case with cluster-like headache caused by acute lymphocytic leukemia infiltration of periorbital tissue.

2004 ◽  
Vol 118 (6) ◽  
pp. 450-452 ◽  
Author(s):  
Chul Ho Jang ◽  
Young Ho Kim

This paper reports an unusual case in which aseptic meningitis presented with sudden sensorineural hearing loss (SSNHL) associated with intralabyrinthine haemorrhage (ILH). A seven-year-old girl presented with sudden right-sided hearing loss with dizziness. She did not have a previous history of bleeding disorders. This child was assessed using audiograms and magnetic resonance imaging (MRI). The patient's hearing loss was irreversible. Steroid therapy was not effective. SSNHL associated with ILH can be one of the negative prognostic factors in children.


2019 ◽  
Vol 3 (4) ◽  
pp. 444-445
Author(s):  
Daniel Quesada ◽  
Matthew Stapleton ◽  
Jadipak Heer ◽  
Phillip Aguìñiga-Navarrete ◽  
Luke Kim

Neuroretinitis from neurosyphilis is an uncommon finding in previously healthy young individuals. A 37-year-old presented with three days of painless, unilateral vision loss with an associated diffuse erythematous non-pruritic truncal rash. Physical exam demonstrated vision loss in the left eye. Fundoscopic exam showed unilateral peripapillary hemorrhage, papilledema and venous engorgement. Labs showed positive syphilis antibody qualitative. Magnetic resonance imaging demonstrated 12 millimeters of high right frontal lobe cerebrospinal fluid density. The patient was treated with benzylpenicillin and within 18 hours had improvement of his vision.


2012 ◽  
Vol 03 (01) ◽  
pp. 89-92 ◽  
Author(s):  
Archana B Netto ◽  
Sanjib Sinha ◽  
Arun B Taly ◽  
Chandrajit Prasad ◽  
A Mahadevan ◽  
...  

ABSTRACTWe report an unusual case of unilateral limb pseudo hypertrophy in a 21-year-old lady who developed progressive enlargement of the right calf followed by thigh in association with chronic leg pain. Magnetic resonance imaging (MRI) of the affected limb confirmed enlargement of various muscles. Electromyography revealed neurogenic features consistent with S1 radiculopathy. MRI of the lumbosacral spine showed tethered cord with a lipoma infiltrating multiple sacral roots. Our case illustrates that muscular pseudo hypertrophy may follow chronic denervation as a consequence of spinal neural compressive disease. The various mechanisms postulated for this distinct condition are outlined.


2008 ◽  
Vol 10 (1) ◽  
pp. 11-14 ◽  
Author(s):  
Nicola Morelli ◽  
Ilaria Pesaresi ◽  
Gianfranco Cafforio ◽  
Maria Rosaria Maluccio ◽  
Sara Gori ◽  
...  

Author(s):  
Kourosh Goudarzipour ◽  
Ahmad Mohammadi ◽  
Reza Taherian ◽  
Mehran Arab Ahmadi ◽  
Behdad Behnam ◽  
...  

Acute lymphocytic leukemia (ALL) is one of the frequent malignancies in pediatrics and involves bone marrow and extramedullary sites. Proptosis as extramedullary involvement of leukemia usually present in acute and chronic myeloid leukemia. It is extremely rare for ALL to present initially as proptosis.Here, a-21-month-old boy was presented with proptosis without any associated symptoms except lymphadenopathy. He was referred with the impression of malignancy from an ophthalmologist. After bone marrow biopsy which showed 33% blast cells, all positive for CD10, CD19, and CD79, the diagnosis of pre-B cell ALL was finally made. His symptoms were improved completely 16 days after starting standard protocol for ALL.Afterone-year follow-up, he was free of any symptoms.According to this initial presentation of ALL and no typical associated symptoms, it is important to make rapid diagnosis and start the treatment in the childhood.


Neurosurgery ◽  
1988 ◽  
Vol 23 (5) ◽  
pp. 666-668 ◽  
Author(s):  
Eduardo Kanterewicz ◽  
Enric Condom ◽  
Juan D. Cañete ◽  
Josá A. Del Olmo

Abstract We describe an unusual case of unifocal eosinophilic granuloma of the spine in a 38-year-old woman who presented with spinal cord compression. After 2 years of back pain, x-ray films of the spine were normal, but computed tomography and magnetic resonance imaging demonstrated a lytic lesion of the 1st lumbar vertebral body with cephalic extension in the epidural space. The lesion was later confirmed at operation to be an eosinophilic granuloma spreading into the surrounding tissues.


2015 ◽  
Vol 33 (6) ◽  
pp. 610-615 ◽  
Author(s):  
Sue C. Kaste ◽  
Deqing Pei ◽  
Cheng Cheng ◽  
Michael D. Neel ◽  
W. Paul Bowman ◽  
...  

Purpose Hip osteonecrosis frequently complicates treatment with glucocorticoids. When extensive (affecting ≥ 30% of the epiphyseal surface), 80% of joints collapse within 2 years, so interventions are needed to prevent this outcome. Patients and Methods This prospective cohort magnetic resonance imaging (MRI) screening study included all consecutive children treated for acute lymphoblastic leukemia on a single protocol. Hip MRI was performed at 6.5 and 9 months from diagnosis (early screening) and at completion of chemotherapy (final evaluation) to determine whether screening could identify extensive hip osteonecrosis before symptom development. Results Of 498 patients, 462 underwent screening MRI. Extensive asymptomatic osteonecrosis was identified by early screening in 26 patients (41 hips); another four patients (seven hips) were detected after the screening period, such that screening sensitivity was 84.1% and specificity was 99.4%. The number of joints screened to detect one lesion was 20.1 joints for all patients, 4.4 joints for patients older than 10 years, and 198 joints for patients ≤ 10 years old (P < .001). Of the 40 extensive lesions in patients older than 10 years, 19 required total hip arthroplasty and none improved. Of eight extensive lesions in younger patients, none required arthroplasty and four improved. Conclusion In patients age 10 years old or younger who require prolonged glucocorticoid therapy, screening for extensive hip osteonecrosis is unnecessary because their risk is low and lesions tend to heal. In children older than 10 years, early screening successfully identifies extensive asymptomatic lesions in patients who would be eligible for studies of interventions to prevent or delay joint collapse.


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