Surface integrity determination of aluminum plates using laser-generated Lamb waves

Objective: A simple, sensitive, precise, and accurate stability indicating HPTLC (high-performance thin-layer chromatography) method for analysis of 10-gingerol in ginger has been developed and validated as perICH guidelines.Methods: The separation was achieved on TLC (thin layer chromatography) aluminum plates pre-coated with silica gel 60F254 using n-hexane: ethyl acetate 55:45 (%, v/v) as a mobile phase. Densitometric analysis was performed at 569 nm.Results: This system was found to have a compact spot of 10-gingerol at RF value of 0.57±0.03. For the proposed procedure, linearity (r2 = 0.998±0.02), limit of detection (18ng/spot), limit of quantification (42 ng/spot), recovery (ranging from 98.35%–100.68%), were found to be satisfactory.Conclusion: Statistical analysis reveals that the content of 10-gingerol in different geographical region varied significantly. The highest and lowest concentration of 10-gingerol in ginger was found to be present in a sample of Patna, Lucknow and Surat respectively which inferred that the variety of ginger found in Patna, Lucknow are much superior to other regions of India.

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Determination of ultrasonic wave velocities and phase velocity dispersion curves of an Inconel 600 plate using resonant ultrasound spectroscopy and leaky Lamb waves

Ultrasonics ◽

10.1016/j.ultras.2004.01.031 ◽

2004 ◽

Vol 42 (1-9) ◽

pp. 551-555 ◽

Cited By ~ 8

Author(s):

Young H Kim ◽

Sung-Jin Song ◽

Sung-Duk Kwon ◽

Yong-Moo Cheong ◽

Hyun-Kyu Jung

Keyword(s):

Phase Velocity ◽

Velocity Dispersion ◽

Lamb Waves ◽

Resonant Ultrasound Spectroscopy ◽

Inconel 600 ◽

Wave Velocities ◽

Phase Velocity Dispersion ◽

Leaky Lamb Waves ◽

Resonant Ultrasound

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High Frequency Ultrasonic Measurements

Measurement and Control ◽

10.1177/002029408802100501 ◽

1988 ◽

Vol 21 (5) ◽

pp. 133-136

Author(s):

N Zarsav

Keyword(s):

High Frequency ◽

Polymer Coating ◽

Steel Sheet ◽

Lamb Waves ◽

Thin Plates ◽

Design Features ◽

Degree Of Cure ◽

Double Probe ◽

Ultrasonic Measurements

The use of high frequency ultrasonic Lamb waves to measure the thickness of thin plates and foils, is discussed and the feasibility of their application to the determination of the degree of cure of polymer coating on coated tin plated steel sheet (as used by the food can industry) is evaluated. The paper also discusses briefly the design features of the purpose built precision double probe ultrasonic goniometer used to carry out these measurements.

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Surface Integrity Investigation to Determine Rough Milling Effects for Assessment of Machining Allowance for Subsequent Finish Milling of Alloy 718

Journal of Manufacturing and Materials Processing ◽

10.3390/jmmp5020048 ◽

2021 ◽

Vol 5 (2) ◽

pp. 48

Author(s):

Jonas Holmberg ◽

Anders Wretland ◽

Johan Berglund ◽

Tomas Beno ◽

Anton Milesic Karlsson

Keyword(s):

Surface Integrity ◽

Milling Process ◽

Depth Of Cut ◽

Machined Surface ◽

Milling Operations ◽

Milling Operation ◽

Machining Allowance ◽

Rough Milling

The planned material volume to be removed from a blank to create the final shape of a part is commonly referred to as allowance. Determination of machining allowance is essential and has a great impact on productivity. The objective of the present work is to use a case study to investigate how a prior rough milling operation affects the finish machined surface and, after that, to use this knowledge to design a methodology for how to assess the machining allowance for subsequent milling operations based on residual stresses. Subsequent milling operations were performed to study the final surface integrity across a milled slot. This was done by rough ceramic milling followed by finish milling in seven subsequent steps. The results show that the up-, centre and down-milling induce different stresses and impact depths. Employing the developed methodology, the depth where the directional influence of the milling process diminishes has been shown to be a suitable minimum limit for the allowance. At this depth, the plastic flow causing severe deformation is not present anymore. It was shown that the centre of the milled slot has the deepest impact depth of 500 µm, up-milling caused an intermediate impact depth of 400 µm followed by down milling with an impact depth of 300 µm. With merged envelope profiles, it was shown that the effects from rough ceramic milling are gone after 3 finish milling passes, with a total depth of cut of 150 µm.

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A VALIDATED METHOD FOR THE DETERMINATION OF TAPENTADOL HYDROCHLORIDE IN BULK AND ITS PHARMACEUTICAL FORMULATION BY DENSITOMETRIC ANALYSIS

INDIAN DRUGS ◽

10.53879/id.49.12.p0051 ◽

2012 ◽

Vol 49 (12) ◽

pp. 51-55

Author(s):

S Kathirvel ◽

◽

K. Madhu Babu

Keyword(s):

Mobile Phase ◽

High Performance ◽

Dosage Form ◽

Chromatographic Method ◽

Glacial Acetic Acid ◽

Calibration Plot ◽

Pharmaceutical Dosage Form ◽

Aluminum Plates ◽

Tablet Dosage

Described in this manuscript is the first reported new, simple high performance thin layer chromatographic method for the determination of tapentadol hydrochloride in bulk and its tablet dosage form. The drug was separated on aluminum plates precoated with silica gel 60 F254 with butanol: water: glacial acetic acid in the ratio of 6:2:2 (v/v/v) as mobile phase. Quantitative analysis was performed by densitometric scanning at 254 nm. The method was validated for linearity, accuracy, precision and robustness. The calibration plot was linear over the range of 200-600 ng band -1 for tapentadol hydrochloride. The method was successfully applied to the analysis of drug in a pharmaceutical dosage form.

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Application of TLC-Spectrodensitometric and Chemometric Methods for Determination of Momenta® Cream: A Comparative Study Applied on Ternary Mixture

Austin Journal of Analytical and Pharmaceutical Chemistry ◽

10.26420/austinjanalpharmchem.2021.1131 ◽

2021 ◽

Vol 8 (1) ◽

Author(s):

Salem H ◽

◽

Omar MA ◽

Derayea SM ◽

Khalil AA ◽

...

Keyword(s):

Comparative Study ◽

Pharmaceutical Preparation ◽

Ternary Mixtures ◽

Principle Component Regression ◽

Ich Guidelines ◽

Miconazole Nitrate ◽

Aluminum Plates ◽

Analytical Approaches ◽

Chloroform Methanol

A comparative study for the validation and advancement of two analytical approaches applied for the simultaneous determination of Mometasone Furoate (MF), Miconazole Nitrate (MIC) and Gentamicin (GM) formulated in Momenta® cream. The first approach was TLC-spectrodensitometric method, which was advanced by separating the three components on TLC aluminum plates coated with silica gel 60 F254 using chloroform: methanol: formic acid (4:0.3:0.15, v/v/v) as a mobile phase, then scanned at 254nm using Camage TLC scanner 3 operated in reflectance-absorbance mode. The second approach was the chemometric method using two models: Partial Least Squares (PLS) and Principle Component Regression Model (PCR). The proposed approaches were validated according to ICH guidelines and were applied for the determination of the ternary mixtures in their analytical mixtures and pharmaceutical preparation.

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