scholarly journals Silver Nanoparticles as a New Generation of Antimicrobial Prophylaxis

Author(s):  
Ilnur T. Garipov ◽  
Renat R. Khaydarov ◽  
Olga U. Gapurova ◽  
Rashid A. Khaydarov ◽  
Firdaus M. Lutfi ◽  
...  

Over the last 20 years, metallic silver in the form of Ag nanoparticles has made a remarkable comeback as an example of a nanomaterial for control of microorganisms. The purpose of our study was a) to quantitatively estimate the antimicrobial effect of silver nanoparticles compared with that of silver ions and b) to check the efficacy of nanosilver as an antimicrobial agent against a range of microbes on the surface of water-soluble paint, 100% cotton fabric, and fibrous chemisorbent. Minimum inhibitory concentration tests quantitatively showed that Ag nanoparticles were less efficient than Ag+ ions against representatives of gram-positive / gram-negative bacteria and cosmopolitan saprotrophic fungi. Antifungal/antibacterial effects against Aspergillus niger, Penicillium phoeniceum, and Staphylococcus aureus were confirmed for nanosilver concentrations of even 1 μg/cm2 on the surface of cotton fabric and 0.8 μg/cm2 in water-soluble paint. As the concentration of nanosilver in water-soluble paint/cotton fabric was increased to 7 μg/cm2, the growth of Bacillus subtilis and Escherichia coli was suppressed as well. Microbiological tests conducted over a period of 60 days showed that there was no biofilm growth on the surface of a silver nanoparticle-coated fiber sorbent during its everyday operation as a household water treatment filter. Thus, silver nanoparticles as an add-on to water-soluble paints, textile fabrics or fiber chemisorbents had a remarkable antibacterial/antifungal effect, although some of the Ag nanoparticles were agglomerated into larger colloidal clusters

Materials ◽  
2019 ◽  
Vol 12 (19) ◽  
pp. 3185
Author(s):  
Morena Nocchetti ◽  
Anna Donnadio ◽  
Eleonora Vischini ◽  
Tamara Posati ◽  
Stefano Ravaioli ◽  
...  

A layered insoluble inorganic-organic solid, namely zirconium phosphate glycine-N,N-bismethylphosphonate, was used to prepare dispersions of nanosheets to support active metals such as metallic silver nanoparticles and zinc ions. Zr phosphate-phosphonate microcrystals were first exfoliated with methylamine to produce a stable colloidal dispersion and then the methylamine was removed by treatment with hydrochloric acid. The obtained colloidal dispersion of Zr phosphate-phosphonate nanosheets was used to immobilize silver or zinc cations, via ion exchange, with the acidic protons of the sheets. The layered matrix showed a great affinity for the metal cations up taking all the added cations. The treatment of the dispersions containing silver ions with ethanol yielded metal silver nanoparticles grafted on the surface of the layered host. The samples were characterized by X-ray powder diffraction, elemental analysis transmission electron microscopy, and selected samples were submitted to antimicrobial tests. The nanocomposites based on Ag nanoparticles showed good bactericidal properties against the bacterial reference strain Staphylococcus epidermidis (S. epidermidis).


2014 ◽  
Vol 2014 ◽  
pp. 1-11 ◽  
Author(s):  
M. A. El-Sheikh

The water soluble photoinitiator (PI) 4-(trimethyl ammonium methyl) benzophenone chloride is used for the first time in the synthesis of silver nanoparticles (AgNPs). A new green synthesis method involves using PI/UV system, carboxymethyl starch (CMS), silver nitrate, and water. A mechanism of the reduction of silver ions to AgNPs by PI/UV system as well as by the newly born aldehydic groups was proposed. The synthesis process was assessed by UV-vis spectra and TEM of AgNPs colloidal solution. The highest absorbance was obtained using CMS, PI and AgNO3concentrations of 10 g/L, 1 g/L, and 1 g/L, respectively; 40°C; 60 min; pH 7; and a material : liquor ratio 1 : 20. AgNPs so-obtained were stable in aqueous solution over a period of three weeks at room temperature (~25°C) and have round shape morphology. The sizes of synthesized AgNPs were in the range of 1–21 nm and the highest counts % of these particles were for particles of 6–10 and 1–3 nm, respectively.


2017 ◽  
Vol 396 ◽  
pp. 461-470 ◽  
Author(s):  
S. Ferraris ◽  
M. Miola ◽  
A. Cochis ◽  
B. Azzimonti ◽  
L. Rimondini ◽  
...  

2020 ◽  
Vol 9 (1) ◽  
pp. 203-210

The available controlling agents for mosquito vectors are chemical insecticides and the frequent usage of these insecticides creating resistance among mosquito vectors and environmental pollutions. Thus, the study was designed to synthesize and characterize the Ag nanoparticles (AgNPs) through a methanol leaf extract of Ocimum canum and find the larvicidal prospective of the AgNPs on the 4th instar larvae of Anopheles stephensi, Culex quinquefasciatus, and Aedes aegypti. The obtained outcomes show that the methanol leaf extract of O. canum was effectively reduced the silver ions and produce constant silver nanoparticles. It was characterized and confirmed by various scientific techniques such as UV-vis spectrum, XRD, SEM, FT-IR and EDaX. Various concentrations (10, 50, 150, 200, and 250 ppm) of characterized nanoparticles were tested for larvicidal activity. The premier larval death was observed at 24 h of treatment on A. aegypti with LC50= 17.03 ppm, followed by C. quinquefasciatus with LC50= 14.89 ppm of methanol extract of O. canum and no death was noticed on A. stephensi. The LD90 value for A. aegypti and C. quinquefasciatus were 24.18 & 20.65 ppm respectively. Hence, the Ag nanoparticles produced from methanol leaf extract of O. canum retains efficiency to control A. aegypti and C. quinquefasciatus. Thus, it might support partially to replace the chemical insecticide which used against these vectors and might contribute to reduce environmental pollution.


2020 ◽  
Vol 71 (2) ◽  
pp. 273-279
Author(s):  
Daniela Gitea ◽  
Andrei Teodorescu ◽  
Carmen Pantis ◽  
Delia Mirela Tit ◽  
Alexa Florina Bungau ◽  
...  

Silver nanoparticles (AgNPs) ranging in size from 1-100 nm show good application potential in many medical fields (therapies, medical devices, molecular diagnostics) due to their antimicrobial properties. The purpose of this study is to characterize from physicochemical perspective the colloidal dispersion obtained through phyto-synthesis. The existence of colloidal silver particles was visually highlighted through Thyndall effect. The bio-reduction of silver ions was analyzed through modern techniques, UV-VIS spectrophotometry and Hyperspectral Microscopy. After getting the colloidal dispersion, its antibacterial activity was proved by sowing on different plates the following types of pathogenic agents: Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa. The UV-VIS spectrum for the methanolic extract with 10% H. perforatum L. and for the silver colloidal dispersions was achieved, observing a max at 455 nm. The hyperspectral images were achieved observing the shape, conformation, and the size of the obtained particles. During the antibacterial efficacy testing on those three strains of pathological agents, in all situations, the colloidal dispersion had a promising antimicrobial effect.


2021 ◽  
Vol 2021 ◽  
pp. 1-15
Author(s):  
Luis Jesús Villarreal-Gómez ◽  
Graciela Lizeth Pérez-González ◽  
Nina Bogdanchikova ◽  
Alexey Pestryakov ◽  
Vadim Nimaev ◽  
...  

The antimicrobial bioactivity of silver nanoparticles is well known, and they can be used widely in many applications, becoming especially important in the biomedical industry. On the other hand, the electrospun nanofibers possess properties that can enhance silver nanoparticle applicability. However, silver nanoparticle bioactivity differs depending on the loading of silver ions into electrospun nanofibers. This review is aimed at comparing different silver incorporation methods into electrospun nanofibers and their antimicrobial activity, discussing each procedure’s limitations, and presenting the most promising one. This review showed that the preferred techniques for incorporating silver nanoparticles were direct blending and ultraviolet irradiation methods due to their simplicity and efficient results. Besides, polyacrylonitrile nanofibers (PAN) have been the most reported system loaded with silver nanoparticles. Finally, independently of the technique used, silver nanoparticle-loaded nanofibers show high antimicrobial activity in all cases.


2012 ◽  
Vol 441 ◽  
pp. 356-359
Author(s):  
Jun Natsuki ◽  
Takao Abe

This paper describes a new method to prepare silver nanoparticles useful for printing electronic circuits. We have tried to develop a silver nitrate reduction method, with which a certain reducing agent has played an important role in the reduction of silver ions in an aqueous solution. The reduction has occurred rapidly at room temperature and the silver particles have been separated very easily from the solution in a short time. In this process, any organic solvent has not been used and separation of silver nanoparticles has not been complicated. All chemicals used in this study have been water-soluble. Small and relatively uniform particles of a diameter lower than 10 nm can be obtained with high purity and high yield. These can result in low cost, safe treatment and good for environment protection. This method of producing colloidal silver nanoparticles will find practical use in electronics applications.


Membranes ◽  
2018 ◽  
Vol 8 (3) ◽  
pp. 59 ◽  
Author(s):  
Shalv Parekh ◽  
Rebecca David ◽  
Kranthi Bannuru ◽  
Lakshminarasimhan Krishnaswamy ◽  
Avinash Baji

The scarcity of drinking water and the contamination of water sources in underdeveloped countries are serious problems that require immediate low-tech and low-cost solutions. In this study, we fabricated polyacrylonitrile (PAN) porous membranes coated with silver nanoparticles (AgNP) and demonstrated their use for water filtration and water treatment applications. The membranes were prepared by electrospinning a PAN solution and treating in a hydroxylamine (NH2OH) aqueous solution to form –C(NH2)N–OH groups that were used for functionalization (Ag+ ions) of the membrane. The coordinated silver ions were then converted to silver nanoparticles. The microstructure of the membrane, water permeability, antimicrobial effect (using Escherichia coli), and particulate filtration capabilities were studied. This study verified that the membrane demonstrated a 100% reduction for Gram-negative bacteria with an effective filtration rate of 8.0 mL/cm2 min. Furthermore, the membrane was able to eliminate 60% of latex beads as small as 50 nm and over 80% of the 2 µm beads via gravity filtration. This study demonstrated that PAN–AgNP membranes can be employed as antimicrobial membranes for the filtration of water in underdeveloped countries.


RSC Advances ◽  
2016 ◽  
Vol 6 (65) ◽  
pp. 60513-60521 ◽  
Author(s):  
Zoya Zaheer ◽  
Elham Shafik Aazam ◽  
Shokit Hussain

Natural biodegradable polymeric starch capped Ag-nanoparticles (AgNPs) were prepared by using extract of Dioscorea deltoidea in the presence of starch.


2007 ◽  
Vol 15 (5) ◽  
pp. 357-363 ◽  
Author(s):  
Dirk Pohle ◽  
Cornelia Damm ◽  
Johanna Neuhof ◽  
Alfons Rösch ◽  
Helmut Münstedt

Materials exhibiting an antimicrobial effect are especially advantageous for medical textiles which are in very close and long-term contact with human skin. Orthopaedic stockings made of terry cotton and polyamide were coated with silver nanoparticles by a simple dip coating process under mild conditions. Both textiles released silver ions over at least 28 days. The silver ion release for both materials is governed by diffusion. The amount of silver ions released by the cotton textile was higher than by the nylon stockings by about a factor of 4. The reason was a larger silver reservoir in the cotton sample, because it contains much more silver than the nylon fabric. As expected from the results of the Ag+ release tests, both these silver coated textiles were active against Escherichia coli.


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