scholarly journals Military surgery research laboratory — yesterday, today, tomorrow…

2021 ◽  
Vol 23 (2) ◽  
pp. 261-272
Author(s):  
Alexey V. Denisov ◽  
Konstantin P. Golovko ◽  
Artem M. Nosov ◽  
Pyotr G. Alisov ◽  
Elena V. Dmitrieva
Keyword(s):  
Research Laboratory ◽  
Interdisciplinary Team ◽  
Combat Trauma ◽  
Wound Ballistics ◽  
Laboratory Animals ◽  
War Surgery ◽  
Trauma Research ◽  
Surgery Research ◽  
History Of ◽  
Surgery Department

Presents the history of organization and development of a unique research unit of the Military Medical Academy named after S.M. Kirov, which is engaged in conducting field experiments and field tests using laboratory animals. The history of the laboratory starts in 1982 with the organization of the combat trauma research laboratory, led by an experienced abdominal surgeon, holder of post-doctoral degree in medicine, professor, colonel of Medical Corps V.A. Popov. Within a short time, the research laboratory succeeded in staffing with highly qualified interdisciplinary team, including surgeons, pathophysiologists, critical care physicians, biochemists, morphologists, microbiologists. This gave the opportunity to carry out research on modern combat trauma not only in the experiments with laboratory animals and on the treatment of casualties admitted to the Academys clinics, but also in the combat environment of Afghanistan war as a mobile interdisciplinary team based at medical institutions of the 40th Army. In June 1993 the Combat Trauma research laboratory was combined with the Shock and Terminal State research laboratory, as a result the War Surgery research laboratory was organized, which joined War Surgery department. The laboratory activity focused on in-depth study of problems of experimental surgery and wound ballistics, pathobiochemistry and pathomorphology of ballistic wound. In July 5, 2011, because of staffing measures the laboratory became part of a newly formed research department (experimental medicine) of the Research Center of the Academy. Then laboratory scientists proceeded with the development of traditional research directions: the study of modern wound ballistics, assessment of weapons damage and protective characteristics of individual body protective facilities (body armor, helmets), carried out in terms of War Surgery, as well as the study of a new type of weapon "nonlethal" weapon, the development of unbiased diagnostic tests and complication prognosis for casualties with multiple trauma, optimization and improvement of treatment policy under variety of conditions. At present, the research laboratory (War Surgery) specialists in cooperation with colleagues of War Surgery department are actively involved in the studies devoted to investigation of combat surgical trauma, effectiveness of modern individual armor, development of medical items and technologies treatment of casualties, taking an active part in the educational process.

In memory of Georgiy Nicolaevich Tsibulyak

2020 ◽  
Vol 22 (4) ◽  
pp. 249-252
Author(s):  
I. M. Samokhvalov ◽  
V. I. Badalov ◽  
N. A. Tiniankin ◽  
P. P. Liashedko ◽  
K. P. Golovko
Keyword(s):  
Research Laboratory ◽  
Traumatic Shock ◽  
Gold Medal ◽  
Clinical Findings ◽  
Terminal State ◽  
Surgical Trauma ◽  
Senior Lecturer ◽  
War Surgery ◽  
Scientific Papers ◽  
Surgery Department

The biography of colonel of Medical Corps, professor Georgiy Nicolaevich Tsibuliak (19322020) is presented. In 1956 G.N. Tsibuliak graduated from the Kirov Military Academy being awarded with gold medal. When being a cadet, he got actively engaged in research. In 1961 G.N. Tsibuliak defended candidates dissertation on the injury treatment in casualties damaged by ionizing radiation, took part in the study of multiple injuries occurring in atomic tests. After graduating from the medical residency he stayed in War Surgery department of the Academy, was eventually assigned as a senior lecturer, the head of the research laboratory carrying out the study of shock and terminal state. In1966 he defended a doctorate in pathogenesis, clinical findings and treatment of tetanus. G.N. Tsibuliak became one of the leading advocates for the concept of traumatic shock in individuals. This fact that at present emergency physicians and surgeons dealing with traumatic shock consider to be an axiom, is scientifically based, and was gained through hard routine work in treating severely injured casualties. From 1976 to 1982 Georgiy Nicolaevich was Surgeon-in-Chief in Group of Soviet Forces in Germany. In 19901993 he was in charge of research laboratory dealing with combat surgical trauma in the Academy. Since 1993 G.N. Tsibuliak had retired from active duty, holding the position of a professor at the War Surgery department. He is the author of more than 200 scientific papers, including 7 monographs. G.N. Tsibuliak was closest associate of A.N. Berkutov in studying traumatic shock in casualties, took an active part in formation of a new clinical specialty resuscitation.

On the occasion of centenary of the birth of I.I.Deriabin (1920–1987)

2020 ◽  
Vol 22 (3) ◽  
pp. 225-231
Author(s):  
I. M. Samokhvalov ◽  
N. A. Tiniankin ◽  
S. A. Matveev ◽  
T. Yu. Suprun ◽  
P. P. Liashedko ◽  
...  
Keyword(s):  
Damage Control ◽  
Military Medicine ◽  
Associate Professor ◽  
100Th Anniversary ◽  
Septic Complications ◽  
War Surgery ◽  
Military Medical Academy ◽  
History Of ◽  
Surgery Department ◽  
The Military

Abstract. On the 2nd of August, 2020 marked the 100th anniversary of the birth of the famous Russian surgeon, the Head of War Surgery department of the Academy, professor, Major-General of the Medical Corps Ilia Ivanovich Deriabin. I.I. Deriabin was the participant of the Great Patriotic War and the war against militarist Japan, the warfare in Afghanistan, the first postwar postgraduate fellow under professor S.I.Banaitis, a student and associate professor of A.N. Bercutov, an officer working many years at War Surgery department, Kirov Military Medical Academy. I.I. Deriabin was also the Head Surgeon to the Group of Soviet Forces in Germany, the founding principal of War Surgery department at the Military Medical faculty, Moscow Central Institute for Advanced Medical Education, Deputy Chief Surgeon of the Soviet Army. In the history of military medicine professor I.I. Deriabin will stay as a great scientist and organizer in the field of War Surgery, a founder of traumatic disease tactical treatment concept, the author of the idea of medical-transport immobilization (anticipating popular modern tactics Damage Control). He also came up with an idea of an improvised frame for unstable pelvic fracture immobilization, developed the technique of peritoneal dialysis (in cooperation with M.N. Lizanets and E.V. Chernov), devised (coauthored with A.C. Rozhkov) multicomponent anti-inflammatory local wound blockade for injury control and septic complications prevention.

Animal Pain Scales in Public Policy

1990 ◽  
Vol 18 (1_part_1) ◽  
pp. 41-50
Author(s):  
F. Barbara Orlans
Keyword(s):  
Public Policy ◽  
Animal Welfare ◽  
The United States ◽  
Pain Scale ◽  
Laboratory Animals ◽  
Practical Applications ◽  
Animal Pain ◽  
Pain Scales ◽  
History Of ◽  
And Control

Pain scales classify the severity of pain inflicted on laboratory animals from little or none up to severe. A pain scale as part of public policy serves beneficial purposes that promote animal welfare. It can be used to educate people about the two alternatives of refinement and replacement, and the need to reduce animal pain. Furthermore, a pain scale has practical applications: 1) in review procedures for animal welfare concerns; 2) in developing policies on the use of animals in education; and 3) as a basis for collecting national data on animal experimentation, so that meaningful data can be collected on trends in reduction and control in animal pain. So far, only a few countries (including Sweden, the Netherlands, Canada and New Zealand) have adopted pain scales as part of their public policy. Most countries, including the United States, have not yet done so. The history of the development and adoption of pain scales by various countries is described and the case is presented for wider adoption of a pain scale in countries not currently using one.

scholarly journals Verbal threat learning does not spare loved ones

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Cristina Morato ◽  
Pedro Guerra ◽  
Florian Bublatzky
Keyword(s):  
Fear Learning ◽  
Pain Experience ◽  
Trauma Research ◽  
Learning History ◽  
Beneficial Effects ◽  
Electric Shocks ◽  
History Of ◽  
Threat Cues ◽  
Verbal Threat

AbstractSignificant others provide individuals with a sense of safety and security. However, the mechanisms that underlie attachment-induced safety are hardly understood. Recent research has shown beneficial effects when viewing pictures of the romantic partner, leading to reduced pain experience and defensive responding. Building upon this, we examined the inhibitory capacity of loved face pictures on fear learning in an instructed threat paradigm. Pictures of loved familiar or unknown individuals served as signals for either threat of electric shocks or safety, while a broad set of psychophysiological measures was recorded. We assumed that a long-term learning history of beneficial relations interferes with social threat learning. Nevertheless, results yielded a typical pattern of physiological defense activation towards threat cues, regardless of whether threat was signaled by an unknown or a loved face. These findings call into question the notion that pictures of loved individuals are shielded against becoming threat cues, with implications for attachment and trauma research.

Memory impairment induced by amphetamine derivatives in laboratory animals and in humans: a review

2012 ◽  
Vol 3 (1) ◽  
pp. 1-12 ◽  
Author(s):  
Jordi Camarasa ◽  
Teresa Rodrigo ◽  
David Pubill ◽  
Elena Escubedo
Keyword(s):  
Illicit Drugs ◽  
Molecular Mechanisms ◽  
Memory Performance ◽  
Laboratory Animals ◽  
Club Drugs ◽  
Synthetic Drugs ◽  
History Of ◽  
Amphetamine Derivatives ◽  
Considerable Body

AbstractThe 20th century brought with it the so-called club drugs (the most notorious being amphetamine derivatives), which are used by young adults at all-night dance parties. Methamphet­amine and 3,4-methylenedioxymethamphetamine (MDMA or ecstasy) are synthetic drugs with stimulant and psychoactive properties that belong to the amphetamine family. Here, we have reviewed the literature about the cognitive impairment induced by these two amphetamine derivatives and the preclinical and clinical outcomes. Although there is controversial evidence about the effect of methamphetamine and MDMA on learning and memory in laboratory animals, results from published papers demonstrate that amphetamines cause long-term impairment of cognitive functions. A large number of pharmacological receptors have been studied and screened as targets of amphetamine-induced cognitive dysfunction, and extensive research efforts have been invested to provide evidence about the molecular mechanisms behind these cognitive deficits. In humans, there is a considerable body of evidence indicating that methamphetamine and MDMA seriously disrupt memory and learning processes. Although an association between the impairments of memory performance and a history of recreational amphetamine ingestion has also been corroborated, a number of methodological difficulties continue to hamper research in this field, the most important being the concomitant use of other illicit drugs.

scholarly journals The Belarusian estate of Ya. F. Golovatsky

2020 ◽  
pp. 442-448
Author(s):  
Yuriy A. Labyntsev ◽  
Larisa L. Shchavinskaya
Keyword(s):  
Research Laboratory ◽  
The Past ◽  
History Of ◽  
The Right

The article describes the history of Votnya, a small estate on the right bank of Dniepr river in Bykhovsky uyezd of Mahilyow Governorate, at the time it belonged to the well-known slavist Ya. F. Golovatsky and his family. After Ya. F. Golovatsky ceased to be a professor of Lviv University, he, a subject of the Austrian Empire, spent here at least two years in total surrounded by the local Belarusians, predominantly Or-thodox. Ya. F. Golovatskij would regularly come here year after year in the summer months. He invested “all his savings” into the development and improvement of his Belarusian estate and created a strong household with a beautiful park. For Ya. F. Golovatsky, Votnya gradually became a vibrant research laboratory to study both the past and the present of Belarusians. This was refl ected, for example, in his assessment of the famous “Dictionary of the Belarusian dialect” by I. I. Nosovich. For many years after the death of the owner of Votnya in 1888, his widow and daughters lived in the estate. It brought income that was also used to create a special scholarship foundation named after Yakov Golovatsky in the framework of the Shevchenko Scientifi c society in Lviv.

scholarly journals Ethical and legal aspects of in vivo experimental biomedical research of the conduct. Part II

2019 ◽  
Vol 27 (2) ◽  
pp. 245-257 ◽  
Author(s):  
Vyacheslav A. Lipatov ◽  
Aleksey A. Kryukov ◽  
Dmitry A. Severinov ◽  
Araik R. Saakyan
Keyword(s):  
Medical Science ◽  
Legal Aspects ◽  
European Convention ◽  
Laboratory Animals ◽  
In Vivo Experiments ◽  
Andreas Vesalius ◽  
History Of ◽  
Animal Care

History of experiments on animals began since the time of the anatomist Andreas Vesalius (XVII century) when experiments on animals (vivisection, from Latin vivus, meaning «alive» and sectio, meaning «cutting», literally «cutting the living tissue») were conducted without anesthesia and were extremely cruel. Nowadays use of laboratory animals considerably differs from that in the time of the first experiments and is regulated by certain legal enactments. The aim of the second part of our work is analysis of legal aspects of using animals in in vivo experiments, in particular, provision of them with adequate anesthesiological support. Normative acts regulating principles of work with laboratory animals in different stages of an experiment are considered: animal care, inclusion into experiment, implementation of experiment, withdrawal of animals from the experiment and determination of animals’ fate after the experiment. International and Russian regulatory framework on this issue, in particular, such documents as European Convention for the Protection of Vertebrate Animals Used for Experimental and Other Scientific Purposes (March 18, 1986, Strasburg), Directive 2010/63/EU on Protection of Animals Used for Scientific Purposes, etc., are considered. Conclusion. At present there exists a sufficient amount of normative enactments regulating implementation of in vivo experimental research. However, most of them require further finalization taking into account recent innovations in medical science and technology. The problem of control of execution of the normative enactments which are in most cases advisory rather than mandatory, remains actual.

scholarly journals 70th ANNIVERSARY OF THE DEPARTMENT OF PEDIATRCI SURGERY OF N. N. BURDENKO VORONEZH STATE MEDICAL UNIVERISTY

2019 ◽  
Vol 8 (4) ◽  
pp. 97-104
Author(s):  
V. A. Vecherkin ◽  
S. N. Gisak ◽  
V. A. Ptitsyn ◽  
N. V. Glagolev ◽  
D. A. Baranov ◽  
...  
Keyword(s):  
Pediatric Surgery ◽  
Research Work ◽  
Gold Medal ◽  
Practical Work ◽  
70Th Anniversary ◽  
History Of ◽  
Surgery Department ◽  
Medical University

The article considers the history of the pediatric surgery department of N. N. Burdenko Voronezh State Medical University. The department was founded in 1947. Based on the results of the research undertaken by associates of the department by now, 3 manuals for doctors and students and 12 collections of scientifc papers were issued and 12 investor’s certifcates were obtained. The role of the Student’s scientifc circle was noted: the students struck 5 gold medals during the last fve years. During the last 8 years, the scientifc circle was considered the best and was awarded a gold medal and frstclass honours degree. A close interrelation between the research work of associates of the pediatric surgery department and practical work of pediatric surgeons from the Central Black Earth region was underlined.

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