scholarly journals Once again about the danger of intrauterine injection of glycerin for the production of artificial premature birth. Objection to Pelzer's article

2020 ◽  
Vol 8 (7-8) ◽  
pp. 698
Author(s):  
V. Strogonov
Keyword(s):  
Premature Birth ◽  
Preterm Labor ◽  
Glycerol Injection

Objection to Pelzer'y, Pf. gives some details of previously reported cases of glycerol injection for the production of preterm labor.

Premature birth (Clinical lecture)

2018 ◽  
pp. 9-12
Author(s):  
I.B. Ventskovskaya ◽  
◽  
V.V. Bila ◽  
O.S. Countryside ◽  
◽  
...  
Keyword(s):  
Magnesium Sulfate ◽  
Key Words ◽  
Gestational Age ◽  
Evidence Based Medicine ◽  
Premature Birth ◽  
Preterm Labor ◽  
Evidence Based ◽  
Advantages And Disadvantages ◽  
Based Medicine ◽  
Tocolytic Agents

The article presents modern views on the pathogenesis of preterm labor, their relevance and classification. From the perspective of evidence-based medicine methods of prevention are considered. A comparison of the main tocolytic agents, their advantages and disadvantages is presented. Key words: premature birth, perinatal and infantile mortality, tocolysis, magnesium sulfate, gestational age.

Optimization of pregnancy tactics and early preterm labor in women after assisted reproductive technologies

2018 ◽  
pp. 104-107
Author(s):  
A.S. Mandrykova ◽  
Keyword(s):  
Peripheral Blood ◽  
Premature Birth ◽  
Preterm Labor ◽  
Assisted Reproductive Technologies ◽  
Reproductive Technologies ◽  
Perinatal Complications ◽  
Premature Rupture ◽  
Practical Medicine ◽  
Objective Reduction ◽  
Ifn Γ

The objective: reduction of the frequency of perinatal complications in women with early preterm labor after the ART, based on the improvement and implementation of the algorithm for diagnostic and therapeutic and prophylactic measures. Materials and methods.We analyzed the course of 130 single-pregnancy pregnancy women with restored fertility after the use of therapeutic assisted reproductive technologies programs that ended with early premature births. The study of the subpopulation composition of lymphocytes and the content of activation markers of peripheral blood lymphocytes was performed using the method of quadratic color laser flow cytometry and a set of monoclonal antibodies. The concentration of cytokines IFN- γ, IL-4, IL-17A, IL-17F, IL-21 and IL-22 in serum of pregnant women was determined by solid-phase immunoassay analysis. The material for studying and analyzing the morpho-functional state of the fetoplacental complex was the results of pathomorphological study of the litter in all cases of early premature birth. By our own research, we established the frequency, structure and leading causes of early premature birth after assisted reproductive technologies, optimized the tactics of conducting induced pregnancies of high obstetric risk, formulated practical recommendations for implementation in practical medicine of Ukraine. Results. For introduction into practical medicine of Ukraine with the purpose of decreasing the frequency of perinatal complications and effective provision of obstetric and gynecological care, we recommend that the following provisions be included in the clinical protocol for the management of pregnancy of high obstetric risk in women after assisted reproductive technologies: 1. To predict the risk of early premature birth in women after ancillary reproductive technologies, the diagnostic algorithm should additionally include the definition of the main indicators of the serum cytokine profile: proinflammatory serum cytokines IFN- γ, IL-2, IL-12, IL-18; anti-inflammatory regulatory cytokine IL-10; quantitative indicators of NK cells with the phenotype CD3-CD16+CD56+, CD94+ lymphocytes and peripheral blood CD71 transferrin. 2. Use of medication correction – Micronized progesterone (200 mg/day). 3. At the gestational age of 28–33 weeks, with the premature rupture of the membranes optimal and effective is the expectant management of pregnancy for 5 days with subsequent delivery of women through the natural birth canal, which makes it possible to achieve the maximum possible degree of maturity of the fetus with a minimum risk of ascending infection in newborns. Conclusions. The effectiveness of our improved algorithm is a significant reduction in women after assisted reproductive technologies, early preterm labor (2.8 times), placental dysfunction (2.3 times), premature rupture of the membranes (in 2, 1 time), fetal distress (3,6 times), abdominal degeneration (2.9 times) and implementation of intraaminal infections (2.6 times; p<0.05). The total morbidity of newborns in the early neonatal period decreased 2.4 times, and perinatal losses were absent. Key words: assisted reproductive technologies, RPP, PRPO, markers of activation of lymphocytes, cytokines.

scholarly journals KARAKTERISTIK PERSALINAN PREMATUR DI RSUP PROF. DR. R. D. KANDOU MANADO

e-CliniC ◽  
2015 ◽  
Vol 3 (2) ◽  
Author(s):  
Siva Oroh ◽  
Eddy Suparman ◽  
Hermie M. M. Tendean
Keyword(s):  
High School ◽  
General Hospital ◽  
Gestational Age ◽  
Premature Birth ◽  
Preterm Labor ◽  
Neonatal Morbidity ◽  
Descriptive Study ◽  
High School Education ◽  
Age Group ◽  
History Of

Abstract: Preterm labor is labor that occurs at 20 - <37 weeks gestational age calculated from the first day of the last menstrual period. Preterm labor is one cause of neonatal morbidity and mortality, which is 60-80% worldwide. This was a retrospective and descriptive study using the medical record of the Department of Obstetrics & Gynecology/Prof. Dr. R.D. Kandou General Hospital Manado period of January 1st to December 31st 2013. There were 151 premature labors during that period. The most frequent characteristics were age group 21-34 years, high school education, and house wife. Based on the parity status, the highest number was P0. History of abortion was found only in a small part of samples. The highest number of diseases/complications was rupture of membrane. The most frequent type of labor was spontaneous labor with back of the head position.Keywords: premature birth, premature babyAbstrak: Persalinan prematur adalah persalinan yang berlangsung pada usia kehamilan 20 - <37 minggu dihitung dari hari pertama haid terakhir. Persalinan prematur merupakan salah satu penyebab utama morbiditas dan mortalitas neonatal, yaitu 60-80% di seluruh dunia. Penelitian ini bersifat deskriptif retrospektif dengan memanfaatkan data sekunder berupa catatan medik di Bagian Obstetri Ginekologi/BLU RSUP Prof. Dr. R. D. Kandou Manado periode 1 Januari-31 Desember 2013. Hasil penelitian mendapatkan 151 sampel kasus persalinan prematur. Karakteristik berdasarkan usia ibu terbanyak pada usia 21-34 tahun, pendidikan ibu terbanyak SMA, dan pekerjaan IRT. Berdasarkan paritas didapatkan jumlah tertinggi pada P0, riwayat abortus hanya sebagian kecil ibu, penyakit/penyulit tersering ialah ketuban pecah dini, dan jenis persalinan tersering ialah spontan letak belakang kepala.Kata kunci: persalinan prematur, bayi prematur

scholarly journals Artificial preterm labor in private practice

2020 ◽  
Vol 7 (1) ◽  
pp. 67-69
Author(s):  
B. Feinberg
Keyword(s):  
Caesarean Section ◽  
Cesarean Section ◽  
Private Practice ◽  
Premature Birth ◽  
Preterm Labor ◽  
The Future

Unfortunately, The benefits of Lister's antiseptic science, says Fehling, have been taken advantage of by gynecology to a much greater extent than obstetrics. From obstetric operations to caesarean section, Lister's scholarship brought more benefits than forceps and perforations. It would therefore be desirable that in the future, artificial premature birth under the influence of anti- and asepsis would give both the mother and the fetus better results than at the present time, and then only this operative aid in a state will be replaced, as a cesarean section with conditional shown and perforated.

scholarly journals Prognostic possibilities of relaxin as a marker of preterm birth

2018 ◽  
Vol 67 (2) ◽  
pp. 16-25
Author(s):  
Olga V. Kosyakova ◽  
Olesya N. Bespalova
Keyword(s):  
Premature Birth ◽  
Preterm Labor ◽  
Preterm Births ◽  
Diagnostic Techniques ◽  
Diagnostic Methods ◽  
Premature Delivery ◽  
Premature Births ◽  
Additional Time ◽  
Childhood Morbidity ◽  
Life Threatening

Premature birth is one of the most important problems of modern obstetrics because it is a leading cause of childhood morbidity and mortality in all countries. Annually, > 1 million premature newborns worldwide die from various types of complications, and most of the survivors become disabled. Moreover, according to WHO analysis, most of these children can be saved by developing measures for the early identification of preterm births, which will provide additional time for effective intervention. Currently, available diagnostic methods do not adequately assess the risks of premature delivery owing to the low predictive value of the methods. This makes it necessary to search for predictors of preterm labor that can improve the accuracy of diagnostic techniques. The desired predictors should have a pathogenetic basis, and most importantly, they must contribute to the early detection of life-threatening premature births. The hormone relaxin could be considered to be a promising marker of premature birth because its role in the pathogenesis of premature birth is unquestionable, and the evaluation of its levels is possible during the early stages of pregnancy.

scholarly journals Chemokines Profiling of Patients with Preterm Birth

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Piotr Laudanski ◽  
Adam Lemancewicz ◽  
Pawel Kuc ◽  
Karol Charkiewicz ◽  
Barbara Ramotowska ◽  
...  
Keyword(s):  
Preterm Birth ◽  
Premature Birth ◽  
Preterm Labor ◽  
Biochemical Markers ◽  
Clinical Signs ◽  
Subclinical Infection ◽  
Effective Prevention ◽  
Threatened Preterm Labor ◽  
Term Births

Introduction.Nowadays it is thought that the main cause of premature birth is subclinical infection. However, none of the currently used methods provide effective prevention to preterm labor. The aim of the study was to determine the concentration of selected chemokines in sera of patients with premature birth without clinical signs of infection (n=62), threatened preterm labor (n=47), and term births (n=28).Method.To assess the concentration of chemokines in the blood serum, we used a multiplex method, which allows the simultaneous determination of 40 chemokines per sample. The sets consist of the following chemokines: 6Ckine/CCL21, Axl, BTC, CCL28, CTACK/CCL27, CXCL16, ENA-78/CXCL5, Eotaxin-3/CCL26, GCP-2/CXC, GRO (GROα/CXCL1, GROβ/CXCL2 and GROγ/CXCL3), HCC-1/CCL14, HCC-4/CCL16, IL-9, IL-17F, IL18-BPa, IL-28A, IL-29, IL-31, IP-10/CXCL10, I-TAC/CXCL11, LIF, LIGHT/TNFSF14, Lymphotactin/XCL1, MCP-2/CCL8, MCP-3/CCL7, MCP-4/CCL13, MDC/CCL22, MIF, MIP-3α/CCL20, MIP-3-β/CCL19, MPIF-1/CCL23, NAP-2/CXCL7, MSPα, OPN, PARC/CCL18, PF4, SDF-1/CXCL12, TARC/CCL17, TECK/CCL25, and TSLP.Results.We showed possible implication of 4 chemokines, that is, HCC-4, I-TAC, MIP-3α, and TARC in women with symptoms of preterm delivery.Conclusion.On the basis of our findings, it seems that the chemokines may play role in the pathogenesis of preterm labor. Defining their potential as biochemical markers of preterm birth requires further investigation on larger group of patients.

scholarly journals Prevention of premature birth in pregnant women with vaginal candidiasis

2019 ◽  
pp. 52-57 ◽  
Author(s):  
D. N. Kokoeva ◽  
M. K. Medzhidova ◽  
N. A. Lomova ◽  
N. E. Kan ◽  
V. L. Tyutyunnik
Keyword(s):  
Pregnant Women ◽  
Premature Birth ◽  
Preterm Labor ◽  
Reproductive Tract ◽  
Local Therapy ◽  
Vaginal Candidiasis ◽  
Premature Delivery ◽  
Vaginal Mucosa ◽  
Results Of Treatment ◽  
Yeast Fungi

Candida vulvovaginitis is an infectious lesion of the vulvar and vaginal mucosa caused by Candida yeast fungi. Vaginal candidiasis during pregnancy is associated with spontaneous miscarriages, premature rupture of the fetal membranes, premature birth, and low birth weight babies. Considering the potential risk of premature delivery at fungal invasion at the level of the lower reproductive tract of a pregnant woman, the search for a complex of preventive measures and timely treatment of сandida vulvovaginitis during gestation is of particular interest. The article presents the results of the use of the drug Zalain in 36 pregnant women, with a gestation period of 28 weeks or more with acute candidal vulvaginitis. In the course of the work, the results of local therapy with Zalain were evaluated and its clinical efficacy in the prevention of preterm labor was confirmed. The results of treatment contribute to a significant reduction in the frequency of initiation of preterm labor, as well as a persistent effect for 2-4 weeks after completion of the course in the postpartum period and the absence of early and distant manifestations of candidiasis in newborns.

scholarly journals STUDI LITERATUR HUBUNGAN UMUR IBU DAN PARITAS DENGAN KEJADIAN PERSALINAN PREMATUR

2021 ◽  
Vol 11 (2) ◽  
Author(s):  
Insani Aulia Qisti, Naimah, Asworoningrum Y
Keyword(s):  
Literature Review ◽  
Premature Birth ◽  
Preterm Labor ◽  
Maternal Age ◽  
Google Scholar

Indonesia adalah negara pada urutan kelima dengan persalinan preterm tertinggi di dunia yaitu sebesar 675.700. Persalinan preterm dapat dipengaruhi oleh umur ibu dan paritas. Penelitian ini bertujuan untuk mengetahui hubungan antara umur ibu dan paritas dengan kejadian persalinan prematur. Metode yang digunakan adalah literature review dengan jenis literature review yang digunakan adalah tradisional literature review. Artikel didapatkan dari 4 database yaitu Pubmed, Google Scholar, Cochrane, dan DOAJ. Kata kunci yang digunakan dalam pencarian literatur: “Umur Ibu” , “Paritas” , “Persalinan Prematur” , “Maternal Age” , “Parity” , “Preterm Labor” , “Premature Birth”. Hasil penelitian menunjukkan dari 15 jurnal yang didapatkan, didapatkan hasil bahwa (92,3%) mengatakan ada hubungan antara umur ibu dan persalinan prematur dan (7,7%) mengatakan tidak ada hubungan antara umur ibu dan persalinan prematur, (85,7%) mengatakan ada hubungan antara paritas dengan persalinan prematur dan (14,3%) mengatakan tidak ada hubungan antara paritas dengan persalinan prematur. Terdapat hubungan antara umur ibu dan paritas dengan kejadian persalinan prematur sehingga diharapkan tenaga kesehatan mampu memberikan pendidikan kesehatan dan konseling perencanaan kehamilan, memberikan perawatan antenatal yang sesuai standar serta memberikan informasi dan akses kontrasepsi agar dapat mencegah terjadinya persalinan prematur.

scholarly journals On the initiation of preterm labor with the help of a colpeyrinter and a Chancelier de Ribes balloon

2020 ◽  
Vol 11 (9) ◽  
pp. 910-927
Author(s):  
N. I. Pobedinskiy
Keyword(s):  
Premature Birth ◽  
Preterm Labor ◽  
Single Method

The large number of methods proposed and still proposed for the initiation of premature birth undoubtedly indicates that until now we do not have a single method, with the help of which, with its complete safety, both for the mother and the fetus in the shortest possible time you can probably cause the correct generic activity.

scholarly journals Gambaran persalinan prematur pada kehamilan remaja di RSUP Prof. Dr. R. D. Kandou Manado periode 1 Januari – 31 Desember 2015

e-CliniC ◽  
2016 ◽  
Vol 4 (2) ◽  
Author(s):  
Marnie Ch. Ondang ◽  
Eddy Suparman ◽  
Hermie M.M. Tendean
Keyword(s):  
Premature Birth ◽  
Preterm Labor ◽  
Premature Baby ◽  
Education Level ◽  
Premature Births ◽  
Age Group ◽  
Due Date ◽  
Medical Record Data ◽  
Premature Babies ◽  
Record Data

Abstract: According to WHO, about 13 millions babies were born prematurely in this world, and less than 1 million premature babies die every year. Around 14 million teenagers become mothers every year and more than 90% of young mothers were in developing countries. Rate of premature birth around 10-20% in Indonesia in 2009 which causes Indonesia becomes the big 5 of the most premature births. According to Riskesdas in 2013 pregnancy in the age 10-54 years in Indonesia was 2,68% higher in cities than in suburban/villages. From women aged 10-54 there are 0.02% pregnant women under 15 years old. This was a descriptive retrospective, study using medical record data of the patients who had premature labour among teenagers acording to age, education, job, marital status, parity, health, head presentation. The results showed that of 31 cases of premature labours in teenagers, 22 cases or 70.96% of them are delivered by women age 18 to 19-year-old, the last education level they had in average is high school which is 64.51%, the majority of them, 93.54% are working as housewives, 83.87% are married, 25 cases or 80.64% of them are primigravida, the highest factors of premature baby, 12.90 % is the ruptured amnion which happened far before the due date of the baby’s delivery, and 90.32% of the case is baby’s head in facing-down position. Conclusion: Premature labours were mostly found in the age group of 18 to 19-year-old with ruptured of amnion long before the baby’s delivery as the highest complication factor, and utmost cases with the baby’s head is in facing-down position.Keywords: preterm labor, teenagers. Abstrak: Menurut WHO ± 13 juta bayi lahir prematur di dunia, dan >1 juta bayi yang lahir prematur meninggal setiap tahunnya. Sekitar 14 juta anak remaja wanita menjadi ibu setiap tahun dan lebih dari 90% dari para ibu muda berada di negara berkembang. Angka kelahiran prematur berkisar 10-20% di Indonesia pada tahun 2009 yang menyebabkan Indonesia masuk dalam peringkat kelima dengan kelahiran prematur terbesar. Berdasarkan Riskesdas 2013 kehamilan umur 10-54 tahun di Indonesia adalah 2,68%, di perkotaan lebih tinggi dibanding perdesaan. Di antara wanita umur 10-54 tahun terdapat kehamilan umur <15 tahun (0,02%). Jenis penelitian ialah deskriptif retrospektif, menggunakan data rekam medik pasien yang melahirkan prematur pada usia remaja berdasarkan umur, pendidikan, pekerjaan, status perkawinan, paritas, penyakit/penyulit, presentasi kepala. Dari 31 kasus persalinan prematur pada remaja, didapatkan paling sering pada usia 18-19 tahun sebanyak 22 kasus (70,96%), pendidikan terakhir terbanyak SMA (64,51%), pekerjaan terbanyak IRT (93,54%), dengan status menikah (83,87%) dan jumlah primigravida 25 kasus (80,64%). Penyakit/penyulit persalinan terbanyak Ketuban Pecah Dini (12,90%) dengan presentasi letak kepala (90,32%). Simpulan: Persalinan prematur pada remaja paling sering ditemukan pada kelompok usia 18-19 tahun dan penyulit tertinggi yaitu ketuban pecah dini dengan jenis presentasi kepala tinggi. Kata kunci: persalinan prematur, kehamilan remaja.

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