scholarly journals The criterion and opportunity of organ-saving operations at purulent- inflammatory diseases of uterus and andex in women of reproductive age

1999 ◽  
Vol 48 (3) ◽  
pp. 19-21
Author(s):  
S. F. Bagnenko ◽  
E. I. Novikov ◽  
I. A. PIakhotnikov ◽  
E. F. Kira ◽  
A. V. Borisov ◽  
...  

The authors judge, that use of the offered criteria under conditions of highly skilled and specialized hospital makes possible the performance, of mainly less invasive organ-saving operations in women of reproductive age at purulent - inflammatory diseases of uterus and adnex.

2017 ◽  
Vol 23 (2) ◽  
Author(s):  
Natalya Drohomyretska

Hemomicrocirculatory system – is a complex structure that reacts in every pathological process even before the clinical period and takes the first blow. The study of microhemocirculation will provide an opportunity to solve the important for practical medicine questions of pathogenesis of many diseases, as for the prevention and treatment of regional disorders of blood circulation.The objective of the research is to study the state of the hemomicrocirculatory bed (HMCB) of adventitia of varicose veins of the small pelvis (VVSP) in women with chronic inflammatory processes of the organs of the small pelvis (CIPOSP).Materials and methods of research. To evaluate the restructuring of the HMCB of adventitia of VVSP, the operating material of 12 women of reproductive age was used. Mainly, there were pieces of the ovarian vein. The study of the HMCB in the vein wall was performed by the non-injecting method of silver impregnation according to V.V. Kupriyanov. To standardize the results, the condition of the HMCB of adventitia of the venous wall in norm was studied in 5 women of reproductive age, who died as a result of various traumas.Results of the research. After the performed studies, the structural-morphological changes of the HMCB of the adventitia of the small pelvis veins were revealed. The dilation of capillaries, postcapillaries, postcapillary venules was observed. The diameter of the vessels of the HMCB of the ovarian vein adventitia was: venule – 94.21 ± 1.38 μM in comparison with the norm – 48.78 ± 1.60 μM (p<0.001); post-capillary venules – 46.76 ± 1.04 μM in comparison with the norm – 28.29 ± 1.1.01 μM (p<0.001); the capillaries were 11.22 ± 0.14 μM in comparison with the norm – 8.24 ± 0.16 μM (p<0.05), arterioles – 29.02 ± 0.76 μM in comparison with the norm – 25.19 ± 1.15 μM (p<0.01). The architectonics of the arterioles is almost unchanged. Lumen of venules is filled with formed elements. The structure of capillaries is polymorphic. The capillary net was localized and concentrated or was formed as a thick planar net, the capillaries were expanded. There were arterio-venulous anastomoses. Endothelial nuclei are shortened. In some preparations, the diameter of the arterioles corresponded to the diameter of the collection venules.  Conclusions:1. The first discovered by us changes in HMCB of adventitia of varicose veins of the small pelvis in women with CIPOSP can be one of the pathogenetic links of the development and progression of the varicose vein itself, which in turn aggravates the course of chronic inflammation.      2. The timely appointment of drugs that improve microcirculation will enable to prevent the development of dystrophic changes in the vein wall, improve the course of chronic inflammatory processes and reduce or completely eliminate the syndrome of “chronic pelvic pain”.


2014 ◽  
Vol 63 (5) ◽  
pp. 46-50 ◽  
Author(s):  
Valentina Fiodorovna Dolgushina ◽  
Nadezhda Aanatolyevna Troshina ◽  
TatianaVladimirovna Vladimirovna Nadvikova

The aim of our research was to identify clinical, morphological features of chronic endometritis among women of reproductive age with a hysteromyoma. 150 patients of reproductive age were surveyed. After which women were divided into three groups. The first group consisted of women at whom the hysteromyoma was combined with a chronic endometritis. The second group - chronic endometritis without hysteromyoma. The third group consisted of apparently healthy women who have addressed to the doctor with questions of contraception and pregnancy planning. It is established that the clinical and morphological picture of a chronic endometritis doesn’t depend on existence at such women of a hysteromyoma. At the women surveyed in both the first and second group almost equally often found inflammatory diseases of the pelvic organs, the bottom department of the genitals, hyperplastic process of endometrium, abnormal uterine bleeding. Special difference in activity of inflammatory process in an endometriya depending on the availability at these women hysteromyoma is not revealed. The combination of chronic endometritis with hysteromyoma is more common for women of late reproductive age, in the anamnesis whicht had childbirth, induced abortion.


2018 ◽  
pp. 118-122
Author(s):  
N.V. Drohomyretska ◽  

Violation of hemomicrocirculatory processes is in the basis of the development of diseases of various organs and systems. The study of hemomicrocirculation at all levels allows us to understand the complexity and universality of these processes, as well as opens up new perspectives in the pathogenetic approach to the treatment and prevention of the diseases. The homogeneity of the reaction of all parts of the hemomicrocirculatory bed in various diseases has been proved on the basis of clinico-morphological comparisons. Study of some areas allows us to judge the state of hemomicrocirculation as an integral system. The objective: to study and compare the changes of the hemomicrocirculatory bed (HMCB) of the conjunctiva of the eyeball and adventitia of varicose veins of the small pelvis (VVSP) in women with chronic inflammatory processes of the internal genital organs (CIPIGO). Materials and methods. There were examined 54 women with chronic inflammatory processes of internal genital organs against the background of varicose veins of the small pelvis (group I); 30 – practically healthy women (control group). The age of women was between 18 and 45 years old. Bulbar microscopy was performed using the SHL-2B slit lamp. The results of microscopy were evaluated according to the system of V.S.Volkov et al. To evaluate the restructuring of the HMCB of adventitia of VVSP, the operating material of 12 women of reproductive age was used. Mainly, these were pieces of the ovarian vein. The study of HMCB in the vein wall was performed by the non-injecting method of silver impregnation according to V.V. Kupriyanov. To standardize the results, the state of the HMCB of venous wall adventitia was studied in norm in 5 women of reproductive age, who died as a result of various injuries. Results. Clinical-morphological parallels between changes in the HMCB of the conjunctiva of the eyeball and adventitia of the varicose veins of the small pelvis were revealed after the performed research. The arteriols’ architectonics was almost unchanged. Venules were dilated, twisted, somewhere varicose-enlarged, filled with formed elements. The structure of capillaries was polymorphic. The capillary net was localized and concentrated or shaped in the form of a thick planar net, the capillaries were expanded. In the micropreparations of the adventitia, there were arterio-venular anastomosis. The nuclei of the endothelial cells were shortened. In some preparations, the diameter of the arterioles corresponded to the diameter of the collection venules. Conclusions. 1. Our studies confirm both clinically and pathomorphologically that one of the links of the pathogenesis of CIPIGO, which occur against the background of VVSP, is a violation of HMCB. 2. Firstly, changes in the HMCB of the conjunctiva of the eyeball and adventitia of the varicose veins of the small pelvis in women with CIPIGO show that they are systemic. 3. The results obtained by us prove the necessity of the use of medicines that improve hemomicrocirculation in the treatment of CIPIGO against the background of VVSP. Key words: hemomicrocirculatory bed, bulbar conjunctiva, adventitia, varicose veins of the small pelvis, chronic inflammatory diseases of the small pelvic organs.


Author(s):  
Немченко ◽  
Ulyana Nemchenko ◽  
Григорова ◽  
Ekaterina Grigorova ◽  
Ракова ◽  
...  

Pelvic inflammatory diseases occupy a special place in the structure of general morbidity, and are polymicrobial in nature with dominance of opportunistic microorganisms, in particular bacteria of the family Enterobacteriaceae.The aim was to study the composition of the vaginal microbiota in women of reproductive age with pelvic inflammatory diseases, as well as to determine the sensitivity of isolated microorganisms to antibiotics and bacteriophages.The study included 70women of reproductive age, among them 37were diagnosed with colpitis and cervicitis, 33women in the comparison group (women screened for a diagnosis). Isolated microorganisms were identified by abdominoperineal methods, including the disk diffusion method to determine the sensitivity of microorganism cultures of Enterobacteriaceae family to antibiotics, and the method of crosses (evaluation of lytic activity of bacteriophages by the number of crosses) to determine the sensitivity to specific therapeutic bacteriophages.Vaginal biocenosis was characterized by deficit of lactobacilli (&#60;106CFU/ml in 100%), the presence of conditionally pathogenic microflora: bacteria of Enterobacteriaceae family, coccal flora and Candida fungi. From 60.0 to 89.3% of Enterobacteria strains were resistant to aminoglycosides and quinolones, but also had a low level of sensitivity to therapeutic bacteriophages.The obtained data indicate the reduction of colonization resistance of vaginal mucosa in pelvic inflammatory diseases and specify the need to use medicinal drugs only under medical supervision to prevent clinically significant drug resistance.


2021 ◽  
Vol 4 (1) ◽  
pp. 59-64
Author(s):  
O.I. Letyaeva ◽  
◽  
O.R. Ziganshin ◽  

This paper discusses one of the important gynecological issues, inflammatory diseases of the urogenital tract caused by opportunistic microbes. The treatment and long-term control over these conditions are challenging and depend on their occurrence and high risk of complications. Impaired local anti-infectious protection is one of the risk factors of chronic inflammation. Since the disease may recur even after successful treatment, domestic and foreign authors increasingly focus on immunotherapy as a part of complex strategy and isolated entity. Local immunotherapy may prevent recurrences and activate host defense. This paper describes the management of two women with mixed infections. The first woman with chronic recurrent inflammation (cervicitis caused by U. urealyticum, vulvovaginal candidiasis, and aerobic vaginitis) in whom prior etiological therapy was ineffective received immunotherapy which resulted in long-term remission. The second woman with coexistent papillomavirus infection (genital warts) and bacterial vaginosis received immunotherapy and topical etiological treatment. As a result, clinical symptoms, the size and number of genital warts reduced which greatly facilitated their chemical destruction. KEYWORDS: genital tract, urogenital infections, papillomavirus infection, bacterial vaginosis, local immunity, biofilms. FOR CITATION: Letyaeva O.I., Ziganshin O.R. Pathogenic treatment of the inflammatory diseases of the urogenital tract in women of reproductive age. Russian Journal of Woman and Child Health. 2021;4(1):59–64. DOI: 10.32364/2618-8430-2021-4-1-59-64.


2013 ◽  
Vol 3 (1(7)) ◽  
pp. 51-53
Author(s):  
O.V. Bakun ◽  
O.A. Andriets

This is a study of autoimmune antibodies in women of reproductive age with chronic salpingo-oophoritis. Shown that the study antiovarialnih antibodies has great prognostic value in reproduction.


Author(s):  
N.Ye. Horban ◽  
N.P. Dzys ◽  
O. V. Lynchak ◽  
T.M. Pokanevych

One of the main conditions for the birth of a healthy baby is the gynecological health of the mother. For this reason, the purpose of the work was to assess the state of gynecological health of women in the Kyiv region. In this work, we used the data of departmental statistical reporting of the Ministry of Health of Ukraine about the number of cases of gynecological pathology from 2010-2017. The number of women of the corresponding age was determined according to the State Statistics Service of Ukraine. The relative risk of pathology (taking into account the 95 % confidence interval) from 2010-2013, 2014-2017 in the Kyiv region was evaluated in comparison with the general indicators in Ukraine as well as from 2014-2017 compared to 2010-2013 in the Kyiv region and general data in Ukraine. Separately for the Kyiv region, the frequency of gynecological pathology was determined among women of reproductive age (707 women), who visited Municipal Institution of Kyiv Regional Council “Kyiv Regional Centre for the Mother and Child Health Defense” from 2014 to 2017. The average age of women was 31.66±0.37. In most cases, the residents of the Kyiv region were diagnosed with chronic inflammatory diseases of the pelvic organs (salpingitis, 21.6 ‰). The relative risks of the occurrence of such diseases were determined in the region, compared with Ukraine, and over time. Those, who had menstrual disorders, hyperproliferative processes of the endometrium were more often recorded (10.8% versus 3.1%, p<0.01), and those with inflammatory processes of the pelvic organs more often had cervical dysplasia (19.8 % versus 4.7 %, p<0.001), chronic diseases of the genitourinary system (7.1 % versus 3.2 %, p<0.05) and digestive organs (17.3 % versus 9.6 %, p<0.01), which indicates a possible pathogenetic role of the inflammatory factor in the development of gynecological pathology. The relative risk of gynecological diseases among the women in the Kyiv region showed that the greatest attention is needed to improving the diagnostics of infertility and endometriosis, as well as the prevention and treatment of salpingitis and uterine cancer. Women with menstrual disorder during their visit to a gynecologist should be checked for the presence of hyperproliferative pathology and, in case a woman is diagnosed with other chronic diseases, they should be offered treatment of these areas of inflammation, which can further positively affect their reproductive health.


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