scholarly journals Features of gynecological pathology in women of reproductive age from Kyiv region

2019 ◽  
pp. 62-67
Author(s):  
N.Ye. Horban ◽  
N.P. Dzys ◽  
O. V. Lynchak ◽  
T.M. Pokanevych
Keyword(s):  
Relative Risk ◽  
Chronic Diseases ◽  
Inflammatory Diseases ◽  
Uterine Cancer ◽  
Cervical Dysplasia ◽  
The State ◽  
Reproductive Age ◽  
Inflammatory Factor ◽  
Women Of Reproductive Age ◽  
Pelvic Organs

One of the main conditions for the birth of a healthy baby is the gynecological health of the mother. For this reason, the purpose of the work was to assess the state of gynecological health of women in the Kyiv region. In this work, we used the data of departmental statistical reporting of the Ministry of Health of Ukraine about the number of cases of gynecological pathology from 2010-2017. The number of women of the corresponding age was determined according to the State Statistics Service of Ukraine. The relative risk of pathology (taking into account the 95 % confidence interval) from 2010-2013, 2014-2017 in the Kyiv region was evaluated in comparison with the general indicators in Ukraine as well as from 2014-2017 compared to 2010-2013 in the Kyiv region and general data in Ukraine. Separately for the Kyiv region, the frequency of gynecological pathology was determined among women of reproductive age (707 women), who visited Municipal Institution of Kyiv Regional Council “Kyiv Regional Centre for the Mother and Child Health Defense” from 2014 to 2017. The average age of women was 31.66±0.37. In most cases, the residents of the Kyiv region were diagnosed with chronic inflammatory diseases of the pelvic organs (salpingitis, 21.6 ‰). The relative risks of the occurrence of such diseases were determined in the region, compared with Ukraine, and over time. Those, who had menstrual disorders, hyperproliferative processes of the endometrium were more often recorded (10.8% versus 3.1%, p<0.01), and those with inflammatory processes of the pelvic organs more often had cervical dysplasia (19.8 % versus 4.7 %, p<0.001), chronic diseases of the genitourinary system (7.1 % versus 3.2 %, p<0.05) and digestive organs (17.3 % versus 9.6 %, p<0.01), which indicates a possible pathogenetic role of the inflammatory factor in the development of gynecological pathology. The relative risk of gynecological diseases among the women in the Kyiv region showed that the greatest attention is needed to improving the diagnostics of infertility and endometriosis, as well as the prevention and treatment of salpingitis and uterine cancer. Women with menstrual disorder during their visit to a gynecologist should be checked for the presence of hyperproliferative pathology and, in case a woman is diagnosed with other chronic diseases, they should be offered treatment of these areas of inflammation, which can further positively affect their reproductive health.

scholarly journals The State of the Hemomycocirculatory Bed of Adventitia of Varicose Veins of the Small Pelvis in Women with Chronic Inflammatory Diseases of the Internal Genital Organs

2017 ◽  
Vol 23 (2) ◽  
Author(s):  
Natalya Drohomyretska
Keyword(s):  
Inflammatory Diseases ◽  
Varicose Veins ◽  
Morphological Changes ◽  
Complex Structure ◽  
The State ◽  
Reproductive Age ◽  
Ovarian Vein ◽  
Women Of Reproductive Age ◽  
Vein Wall ◽  
Inflammatory Processes

Hemomicrocirculatory system – is a complex structure that reacts in every pathological process even before the clinical period and takes the first blow. The study of microhemocirculation will provide an opportunity to solve the important for practical medicine questions of pathogenesis of many diseases, as for the prevention and treatment of regional disorders of blood circulation.The objective of the research is to study the state of the hemomicrocirculatory bed (HMCB) of adventitia of varicose veins of the small pelvis (VVSP) in women with chronic inflammatory processes of the organs of the small pelvis (CIPOSP).Materials and methods of research. To evaluate the restructuring of the HMCB of adventitia of VVSP, the operating material of 12 women of reproductive age was used. Mainly, there were pieces of the ovarian vein. The study of the HMCB in the vein wall was performed by the non-injecting method of silver impregnation according to V.V. Kupriyanov. To standardize the results, the condition of the HMCB of adventitia of the venous wall in norm was studied in 5 women of reproductive age, who died as a result of various traumas.Results of the research. After the performed studies, the structural-morphological changes of the HMCB of the adventitia of the small pelvis veins were revealed. The dilation of capillaries, postcapillaries, postcapillary venules was observed. The diameter of the vessels of the HMCB of the ovarian vein adventitia was: venule – 94.21 ± 1.38 μM in comparison with the norm – 48.78 ± 1.60 μM (p<0.001); post-capillary venules – 46.76 ± 1.04 μM in comparison with the norm – 28.29 ± 1.1.01 μM (p<0.001); the capillaries were 11.22 ± 0.14 μM in comparison with the norm – 8.24 ± 0.16 μM (p<0.05), arterioles – 29.02 ± 0.76 μM in comparison with the norm – 25.19 ± 1.15 μM (p<0.01). The architectonics of the arterioles is almost unchanged. Lumen of venules is filled with formed elements. The structure of capillaries is polymorphic. The capillary net was localized and concentrated or was formed as a thick planar net, the capillaries were expanded. There were arterio-venulous anastomoses. Endothelial nuclei are shortened. In some preparations, the diameter of the arterioles corresponded to the diameter of the collection venules.  Conclusions:1. The first discovered by us changes in HMCB of adventitia of varicose veins of the small pelvis in women with CIPOSP can be one of the pathogenetic links of the development and progression of the varicose vein itself, which in turn aggravates the course of chronic inflammation.      2. The timely appointment of drugs that improve microcirculation will enable to prevent the development of dystrophic changes in the vein wall, improve the course of chronic inflammatory processes and reduce or completely eliminate the syndrome of “chronic pelvic pain”.

Clinical and morphological characteristics of chronic endometritis in women with hysteromyoma

2014 ◽  
Vol 63 (5) ◽  
pp. 46-50 ◽  
Author(s):  
Valentina Fiodorovna Dolgushina ◽  
Nadezhda Aanatolyevna Troshina ◽  
TatianaVladimirovna Vladimirovna Nadvikova
Keyword(s):  
Inflammatory Diseases ◽  
Morphological Characteristics ◽  
Abnormal Uterine Bleeding ◽  
Reproductive Age ◽  
Women Of Reproductive Age ◽  
Chronic Endometritis ◽  
Pelvic Organs ◽  
Morphological Picture ◽  
Special Difference ◽  
Apparently Healthy

The aim of our research was to identify clinical, morphological features of chronic endometritis among women of reproductive age with a hysteromyoma. 150 patients of reproductive age were surveyed. After which women were divided into three groups. The first group consisted of women at whom the hysteromyoma was combined with a chronic endometritis. The second group - chronic endometritis without hysteromyoma. The third group consisted of apparently healthy women who have addressed to the doctor with questions of contraception and pregnancy planning. It is established that the clinical and morphological picture of a chronic endometritis doesn’t depend on existence at such women of a hysteromyoma. At the women surveyed in both the first and second group almost equally often found inflammatory diseases of the pelvic organs, the bottom department of the genitals, hyperplastic process of endometrium, abnormal uterine bleeding. Special difference in activity of inflammatory process in an endometriya depending on the availability at these women hysteromyoma is not revealed. The combination of chronic endometritis with hysteromyoma is more common for women of late reproductive age, in the anamnesis whicht had childbirth, induced abortion.

Clinical-morphological parallels in the pathogenesis of chronic inflammatory processes of internal genital organs in women with varicose veins of the small pelvis

2018 ◽  
pp. 118-122
Author(s):  
N.V. Drohomyretska ◽  
Keyword(s):  
Inflammatory Diseases ◽  
Varicose Veins ◽  
The State ◽  
Reproductive Age ◽  
Control Group ◽  
Bulbar Conjunctiva ◽  
Women Of Reproductive Age ◽  
Vein Wall ◽  
Group I ◽  
Inflammatory Processes

Violation of hemomicrocirculatory processes is in the basis of the development of diseases of various organs and systems. The study of hemomicrocirculation at all levels allows us to understand the complexity and universality of these processes, as well as opens up new perspectives in the pathogenetic approach to the treatment and prevention of the diseases. The homogeneity of the reaction of all parts of the hemomicrocirculatory bed in various diseases has been proved on the basis of clinico-morphological comparisons. Study of some areas allows us to judge the state of hemomicrocirculation as an integral system. The objective: to study and compare the changes of the hemomicrocirculatory bed (HMCB) of the conjunctiva of the eyeball and adventitia of varicose veins of the small pelvis (VVSP) in women with chronic inflammatory processes of the internal genital organs (CIPIGO). Materials and methods. There were examined 54 women with chronic inflammatory processes of internal genital organs against the background of varicose veins of the small pelvis (group I); 30 – practically healthy women (control group). The age of women was between 18 and 45 years old. Bulbar microscopy was performed using the SHL-2B slit lamp. The results of microscopy were evaluated according to the system of V.S.Volkov et al. To evaluate the restructuring of the HMCB of adventitia of VVSP, the operating material of 12 women of reproductive age was used. Mainly, these were pieces of the ovarian vein. The study of HMCB in the vein wall was performed by the non-injecting method of silver impregnation according to V.V. Kupriyanov. To standardize the results, the state of the HMCB of venous wall adventitia was studied in norm in 5 women of reproductive age, who died as a result of various injuries. Results. Clinical-morphological parallels between changes in the HMCB of the conjunctiva of the eyeball and adventitia of the varicose veins of the small pelvis were revealed after the performed research. The arteriols’ architectonics was almost unchanged. Venules were dilated, twisted, somewhere varicose-enlarged, filled with formed elements. The structure of capillaries was polymorphic. The capillary net was localized and concentrated or shaped in the form of a thick planar net, the capillaries were expanded. In the micropreparations of the adventitia, there were arterio-venular anastomosis. The nuclei of the endothelial cells were shortened. In some preparations, the diameter of the arterioles corresponded to the diameter of the collection venules. Conclusions. 1. Our studies confirm both clinically and pathomorphologically that one of the links of the pathogenesis of CIPIGO, which occur against the background of VVSP, is a violation of HMCB. 2. Firstly, changes in the HMCB of the conjunctiva of the eyeball and adventitia of the varicose veins of the small pelvis in women with CIPIGO show that they are systemic. 3. The results obtained by us prove the necessity of the use of medicines that improve hemomicrocirculation in the treatment of CIPIGO against the background of VVSP. Key words: hemomicrocirculatory bed, bulbar conjunctiva, adventitia, varicose veins of the small pelvis, chronic inflammatory diseases of the small pelvic organs.

New approaches in complex therapy of inflammatory diseases of the pelvic organs in women of reproductive age

2017 ◽  
pp. 41-44
Author(s):  
O.V. Grischenko ◽  
◽  
T.A. Kozub ◽  
Keyword(s):  
Inflammatory Diseases ◽  
Reproductive Age ◽  
Control Group ◽  
Study Group ◽  
Complex Treatment ◽  
Women Of Reproductive Age ◽  
Urine Ph ◽  
Pelvic Organs ◽  
Standard Scheme ◽  
Group I

The objective: to study the efficacy of complex treatment of inflammatory diseases of the pelvic organs (vaginitis), occurring in conjunction with urinary tract infection (cystitis), with a combined medication of plant origin Tutukon produced by Miguel and Garriga, S. A. ("Grand medical Group AG", Spain/Switzerland) in women of reproductive age. Patients and methods. Were examined 60 women of reproductive age with the presence of vaginitis and associated cystitis. All the patients were divided into two clinical groups. In group I (control; n=30) treatment was carried out according to the standard scheme with the use of antimicrobial drugs, antispasmodics, local antiseptics for the sanitation of the vagina. In group II (study group; n=30) treatment was carried out according to the standard scheme with the inclusion of the drug Tutukon. All the patients were examined at 3-rd, 7-th, 10-th day of treatment and 30 days after discontinuation of therapy. Results. During the research was given the analysis of the dynamics of clinical and laboratory parameters in women of both groups before and after treatment. In patients of study group, the standard therapy which included Tutukon, the treatment was more effective than in patients of control group: a rapid onset of clinical effect, reducing the duration of the disease, a complete clinical response in 90% of cases versus 63%, alkalization of urine - pH 6.5±0.10, the absence of recurrence within 30 days after the end of therapy. Conclusion. Tutukon medicine is recommended for complex treatment of vaginitis, occurring in combination with cystitis in women of reproductive age. Key words: vaginitis, cystitis, dysuria, urine pH, Tutukon.

Pattern of cervical dysplasia among women of reproductive age in Zaria, Northern Nigeria

2014 ◽  
Vol 16 (2) ◽  
pp. 52 ◽  
Author(s):  
SaadA Ahmed ◽  
TeniO Abu ◽  
Adekunle Oguntayo ◽  
JamesA Ndako ◽  
Solomon Avidime
Keyword(s):  
Cervical Dysplasia ◽  
Reproductive Age ◽  
Northern Nigeria ◽  
Women Of Reproductive Age

scholarly journals Association between contemporary hormonal contraception and ovarian cancer in women of reproductive age in Denmark: prospective, nationwide cohort study

BMJ ◽  
2018 ◽  
pp. k3609 ◽  
Author(s):  
Lisa Iversen ◽  
Shona Fielding ◽  
Øjvind Lidegaard ◽  
Lina S Mørch ◽  
Charlotte W Skovlund ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Relative Risk ◽  
Hormonal Contraception ◽  
Reproductive Age ◽  
Hormonal Contraceptives ◽  
Ovarian Cancer Risk ◽  
Women Of Reproductive Age ◽  
Ovarian Cancers ◽  
Study Population ◽  
Combined Hormonal Contraceptives

AbstractObjectivesTo investigate the association between contemporary combined hormonal contraceptives (including progestogen types in combined preparations and all progestogen-only products) and overall and specific types of ovarian cancer.DesignProspective, nationwide cohort study.SettingDenmark, 1995-2014.ParticipantsAll women aged 15-49 years during 1995-2014 were eligible. Women were excluded if they immigrated after 1995, had cancer (except non-melanoma skin cancer), had venous thrombosis, or were treated for infertility before entry (final study population included 1 879 227 women). Women were categorised as never users (no record of being dispensed hormonal contraception), current or recent users (≤1 year after stopping use), or former users (>1 year after stopping use) of different hormonal contraceptives.Main outcome measuresPoisson regression was used to calculate relative risk of ovarian cancer among users of any contemporary combined hormonal contraceptives and by progestogen type in combined preparations and all progestogen-only products, including non-oral preparations. Separate analyses examined women followed up to their first contraception type switch and those with full contraceptive histories. Duration, time since last use, and tumour histology were examined and the population prevented fraction were calculated.ResultsDuring 21.4 million person years, 1249 incident ovarian cancers occurred. Among ever users of hormonal contraception, 478 ovarian cancers were recorded over 13 344 531 person years. Never users had 771 ovarian cancers during 8 150 250 person years. Compared with never users, reduced risks of ovarian cancer occurred with current or recent use and former use of any hormonal contraception (relative risk 0.58 (95% confidence interval 0.49 to 0.68) and 0.77 (0.66 to 0.91), respectively). Relative risks among current or recent users decreased with increasing duration (from 0.82 (0.59 to 1.12) with ≤1 year use to 0.26 (0.16 to 0.43) with >10 years’ use; P<0.001 for trend). Similar results were achieved among women followed up to their first switch in contraceptive type. Little evidence of major differences in risk estimates by tumour type or progestogen content of combined oral contraceptives was seen. Use of progestogen-only products were not associated with ovarian cancer risk. Among ever users of hormonal contraception, the reduction in the age standardised absolute rate of ovarian cancer was 3.2 per 100 000 person years. Based on the relative risk for the never use versus ever use categories of hormonal contraception (0.66), the population prevented fraction was estimated to be 21%—that is, use of hormonal contraception prevented 21% of ovarian cancers in the study population.ConclusionsUse of contemporary combined hormonal contraceptives is associated with a reduction in ovarian cancer risk in women of reproductive age—an effect related to duration of use, which diminishes after stopping use. These data suggest no protective effect from progestogen-only products.

scholarly journals The criterion and opportunity of organ-saving operations at purulent- inflammatory diseases of uterus and andex in women of reproductive age

1999 ◽  
Vol 48 (3) ◽  
pp. 19-21
Author(s):  
S. F. Bagnenko ◽  
E. I. Novikov ◽  
I. A. PIakhotnikov ◽  
E. F. Kira ◽  
A. V. Borisov ◽  
...  
Keyword(s):  
Inflammatory Diseases ◽  
Reproductive Age ◽  
Women Of Reproductive Age ◽  
Less Invasive ◽  
Specialized Hospital ◽  
Highly Skilled

The authors judge, that use of the offered criteria under conditions of highly skilled and specialized hospital makes possible the performance, of mainly less invasive organ-saving operations in women of reproductive age at purulent - inflammatory diseases of uterus and adnex.

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