Meetings of medical societies. Society of Physicians at Kazan University

1927 ◽  
Vol 23 (4) ◽  
pp. 475-479

Meeting of February 24Prof. M. N. Cheboksarov: Adrenal lipase, its relation to poisons and clinical significance. The report was printed in issue 3 of "K.M. Journal". In the debate Prof. P.P. Vasiliev pointed out that microscopic examination of the adrenal glands of dead B., mentioned by the reporter, revealed the existence of changes both in the cortical and in the brain substance of them. Proff. С. С. Zimnitskii and P. N. Nikolaev, noting the practical importance and interest of the reporter's work, pointed out that it would be especially interesting to trace the content of adrenal lipase in such diseases as typhoid and typhoid, as well as in animals with artificial damage to their adrenal glands.

Author(s):  
Sherzod Ibragimov ◽  
Dilafruza Rustamova ◽  
Aziza Ganieva ◽  
Zarina Zubaydilloeva ◽  
Kamilla Raiimzhanova

In this article, we will consider the principle of one of the most tangible and powerful mediators functioning in the body. Adrenaline (epinephrine - in the USA) is simple to outrage, in super stressful situations it turns on and saves a life. He, as a professional bodyguard, is inactive 99% of the time, but at 1%, works quickly, hard, effectively. Adrenaline is generally a hormone, but structurally close to noradrenaline. Similar effects, only with a sense of fear and anxiety. The hormone, which is produced by the brain substance of the adrenal glands, which plays a special role in the adaptation mechanism of the body to stressful circumstances (often they say this: "struggle or flight"). Its effect on the body is quite diverse, it increases the strength and speed of the heartbeat, the frequency and depth of breathing, causes a cast of blood from the skin and digestive system, and flushes to the heart and mice, and also stimulates the production of glucose in the liver to increase the amount of energy by increased breathing. Synthetic adrenaline is used in some cases as a medicine, especially when removing patients from a state of shock or after cardiac arrest.


1992 ◽  
Vol 34 (5) ◽  
pp. 407-410 ◽  
Author(s):  
P. M. Bourgouin ◽  
D. Tampieri ◽  
D. Melancon ◽  
R. del Carpio ◽  
R. Ethier

2021 ◽  
Vol 22 (1) ◽  
pp. 83-86
Author(s):  
O. A. Kicherova ◽  
◽  
L. I. Reikhert ◽  
O. N. Bovt ◽  
◽  
...  

In recent years, cerebral vascular diseases have been increasingly detected in young patients. It is due not only to better physicians’ knowledge about this pathology, but also to the improvement of its diagnosis methods. Modern neuroimaging techniques allow us to clarify the nature of hemorrhage, to determine the volume and location of intracerebral hematoma, and to establish the degree of concomitant edema and dislocation of the brain. However, despite the high accuracy of the research, it is not always possible to establish the cause that led to a brain accident, which greatly affects the tactics of management and outcomes in this category of patients. A special feature of the structure of cerebrovascular diseases of young people is the high proportion of hemorrhagic stroke, the causes of which are most often arterio-venous malformations. Meanwhile, there are a number of other causes that can lead to hemorrhage into the brain substance. These include disorders of blood clotting, and various vasculitis, and exposure to toxic substances and drugs, and tumor formations (primary and secondary). All these pathological factors outline the range of diagnostic search in young patients who underwent hemorrhagic stroke. Diagnosis of these pathological conditions with the help of modern visualization techniques is considered to be easy, but this is not always the case. In this article, the authors give their own clinical observation of a hemorrhagic stroke in a young patient, which demonstrates the complexity of the diagnostic search in patients with this pathology.


1903 ◽  
Vol 3 (3-4) ◽  
pp. 154-155
Author(s):  
M. A. Vasiliev

Beneficial influence is so-called. sexual operations in persons with hypertrophy of prostatae was explained by the advancing atrophy of the last days. But the rapid onset of the result, on the one hand, and the negative data of the microscopic examination of the prostate after the operation, on the other, showed that the atrophy of the prostate was not very good here. In addition to the explanation of this fact, they put a decrease in the congestion of the urinary tract, which was considered an ethological moment for hypertrophy of the prostatae. smyavinoschago duct) on the tone of the sphincteris vesicae, in order to find out in this way partly the clinical significance of these operations.


2021 ◽  
Vol 66 (12) ◽  
pp. 718-721
Author(s):  
Larisa Mikhailovna Obukhova ◽  
I. A. Medyanik ◽  
K. N. Kontorshchikova ◽  
S. A. Simagina ◽  
L. T. Musaelyan ◽  
...  

It has been established that the non-neuronal cholinergic system is related to the oncogenesis which increases the attractiveness of its components as the promising markers of oncologic diseases. The purpose of this work is to evaluate the clinical significance of the analysis of the activity of acetyl cholinesterase as a new marker of gliomas. The activity of acetyl cholinesterase was assessed by photo colorimetric analysis according to the Hestrin method recalculating the activity of the enzyme in the tumor tissue per 1 g of protein, and in the blood - by 0.1 g of hemoglobin. The data obtained in the primary tumors of the brain (28) in the tissue of the brain of persons who died as a result of injury (6) and in whole blood of patients with gliomas (28) and practically healthy people (10) were compared with the use of a number of statistical programs. A significant decrease in the activity of acetyl cholinesterase in tumor tissue and in whole blood is revealed as the degree of anaplasia of tumors increases, starting with Grade II. It is for the first time that a significant direct correlation was noted showing the consistency between the decrease in the activity of acetyl cholinesterase in the tumor tissue of the brain and blood. Bioinformatic analysis showed the connection of the enzyme of acetyl cholinesterase with proteins of the PI3K-AKT and Notch signaling pathways providing antiapoptotic and proliferative effects. The found dependences provide new insights into understanding of the mechanisms of gliomas genesis and can be used for selection of new diagnostic markers of brain tumors.


1870 ◽  
Vol 16 (73) ◽  
pp. 52-58
Author(s):  
J. T. Sabben

In publishing the following cases, recently under my charge, of mental derangement dependent upon atheromatous deposit in the coats of the larger cerebral arteries, without any apparent disease of the brain substance, I desire, if possible, to define the symptoms of that condition during life, so as to enable them to be distinguished from those of general paralysis, with which I believe them often to be confused.


Angiology ◽  
1966 ◽  
Vol 17 (10) ◽  
pp. 771-784 ◽  
Author(s):  
A. Carrato-Ibañez ◽  
F. Abadia-Fenoll
Keyword(s):  

Author(s):  
Tatjana Abaffy ◽  
Hiroaki Matsunami

Abstract Scientific evidence related to the aromatase reaction in various biological processes spanning from mid-1960 is abundant, however, as our analytical sensitivity increases, a new look at the old chemical reaction is necessary. Here, we review an irreversible aromatase reaction from the substrate androstenedione. It proceeds in 3 consecutive steps. In the first two steps, 19-hydroxy steroids are produced. They can dissociate from the enzyme complex and either accumulate in tissues or enter the blood.In this review, we want to highlight the potential importance of these 19-hydroxy steroids in various physiological and pathological conditions. We focus primarily on 19-hydroxy steroids, and in particular on the 19-hydroxyandrostenedione produced by the incomplete aromatase reaction. Using a PubMed database and search terms aromatase reaction,19-hydroxylation of androgens and steroid measurements, we detail the chemistry of the aromatase reaction and list previous and current methods used to measure 19-hydroxy steroids. We present the evidence of the existence of 19-hydroxy steroids in the brain tissue, ovaries, testes, adrenal glands, prostate cancer and also during pregnancy and parturition and in Cushing’s disease. Based on the available literature, a potential involvement of 19-hydroxy steroids in the brain differentiation process, sperm motility, ovarian function, and hypertension is suggested and warrant future research.We hope that with the advancement of highly specific and sensitive analytical methods, future research into 19-hydroxy steroids will be encouraged, as much remains to be learned and discovered.


1979 ◽  
Vol 83 (1) ◽  
pp. 113-118 ◽  
Author(s):  
E. L. BITTMAN ◽  
B. D. GOLDMAN

SUMMARY Female hamsters rendered acyclic by exposure to short photoperiods (10 h light: 14 h darkness) showed diurnal surges of both LH and FSH which persisted after removal of the ovaries and adrenal glands. The reduced increase in gonadotrophin secretion after ovariectomy, typical of hamsters exposed to short days, was also not contingent upon the presence of the adrenal glands. The results demonstrate that 'supersensitivity' of the neuroendocrine axis to feedback of ovarian or adrenal steroids cannot fully account for either the daily surges of gonadotrophins or the diminished response of LH and FSH to ovariectomy in hamsters maintained on short days. It is suggested that these changes result instead from other pineal-mediated actions of short photoperiods upon the brain.


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