Treatment of inflammatory diseases of the female genitalia with X-rays

1927 ◽  
Vol 23 (6-7) ◽  
pp. 746-746
Author(s):  
B. A. Arkhangelsky

The author found that low-dose x-ray therapy (the author used 15-20% NED) is a valuable way to treat inflammatory processes in the female genital area.

1927 ◽  
Vol 23 (4) ◽  
pp. 425-429
Author(s):  
N. S. Utochnikova

The treatment of inflammatory diseases of the female genitalia has long been one of the most important tasks of the gynecologist. With the development of surgery, surgical methods of treatment began to be applied: exudates were removed, the uterus and inflamed appendages were extirpated, etc.; but the danger of surgical intervention on the one hand, and on the other - the severe consequences of removal of organs such as ovaries, especially in young women - forced gynecologists to spend much effort in discovering and improving non-operative methods of treatment of inflammatory diseases of the female genital parts. Among these methods, physical methods such as water, mud, light baths, massage, etc., as well as those related to electricity have long been prominent.


Dose-Response ◽  
2019 ◽  
Vol 17 (2) ◽  
pp. 155932581985281 ◽  
Author(s):  
Paul A. Oakley ◽  
Niousha Navid Ehsani ◽  
Deed E. Harrison

X-rays have been the gold standard for diagnosis, evaluation, and management of spinal scoliosis for decades as other assessment methods are indirect, too expensive, or not practical in practice. The average scoliosis patient will receive 10 to 25 spinal X-rays over several years equating to a maximum estimated dose of 10 to 25 mGy. Some patients, those getting diagnosed at a younger age and receiving early and ongoing treatments, may receive up to 40 to 50 X-rays, approaching at most 50 mGy. There are concerns that repeated radiographs given to patients are carcinogenic. Some studies have used the linear no-threshold model to derive cancer-risk estimates; however, it is invalid for low-dose irradiation (ie, X-rays); these estimates are untrue. Other studies have calculated cancer-risk ratios from long-term health data of historic scoliosis cohorts. Since data indicate reduced cancer rates in a cohort receiving a total radiation dose between 50 and 300 mGy, it is unlikely that scoliosis patients would get cancer from repeated X-rays. Moreover, since the threshold for leukemia is about 1100 mGy, scoliosis patients will not likely develop cancers from spinal X-rays. Scoliosis patients likely have long-term health consequences, including cancers, from the actual disease entity itself and not from protracted X-ray radiation exposures that are essential and indeed safe.


2019 ◽  
Vol 26 (4) ◽  
pp. 912-921 ◽  
Author(s):  
Go Ueno ◽  
Atsuhiro Shimada ◽  
Eiki Yamashita ◽  
Kazuya Hasegawa ◽  
Takashi Kumasaka ◽  
...  

To investigate the effect of high-energy X-rays on site-specific radiation-damage, low-dose diffraction data were collected from radiation-sensitive crystals of the metal enzyme cytochrome c oxidase. Data were collected at the Structural Biology I beamline (BL41XU) at SPring-8, using 30 keV X-rays and a highly sensitive pixel array detector equipped with a cadmium telluride sensor. The experimental setup of continuous sample translation using multiple crystals allowed the average diffraction weighted dose per data set to be reduced to 58 kGy, and the resulting data revealed a ligand structure featuring an identical bond length to that in the damage-free structure determined using an X-ray free-electron laser. However, precise analysis of the residual density around the ligand structure refined with the synchrotron data showed the possibility of a small level of specific damage, which might have resulted from the accumulated dose of 58 kGy per data set. Further investigation of the photon-energy dependence of specific damage, as assessed by variations in UV-vis absorption spectra, was conducted using an on-line spectrometer at various energies ranging from 10 to 30 keV. No evidence was found for specific radiation damage being energy dependent.


2021 ◽  
Vol 18 (3) ◽  
pp. 105-105
Author(s):  
V. G.

This remedy, offered by Oestgeich-Som, contains 15% ol. terebinthini, 0.5% quinine and anesthesin each, 84% ol. olivarum. Having applied it in 22 cases of perimetritis, salpingitis, oophoritis, infiltrates in the posterior Dоnglasen, etc., Schwarz (Deut. Med. Woch., 1921, No. 52) was very pleased with the results.


2021 ◽  
Vol 2 (1) ◽  
pp. 70-78
Author(s):  
Pavel D. Pankov ◽  
Magomet KH. Salpagarov ◽  
Natalia N. Yakovleva ◽  
Alexey V. Andronov ◽  
Grigory А. Baranov ◽  
...  

In this article provides an overview of publications by foreign authors of the novel coronavirus (SARS-CoV-2) and introduce a modified treatment method for COVID-19-associated pneumonia. X-ray therapy was used to treat pneumonia during the first half of the 20th century. Fifteen studies report that approximately 700 cases of bacterial (lobar and bronchopneumonia), sulfanilamide non-responsive, interstitial, and atypical pneumonia were effectively treated by low doses of X-rays, leading to disease resolution, based on clinical symptoms, objective disease biomarkers, and mortality incidence. The capacity of the X-ray treatment to reduce mortality was similar to serum therapy and sulfonamide treatment during the same time period. The mechanism by which the X-ray treatment acts upon pneumonia involves the induction of an anti-inflammatory phenotype that leads to a rapid reversal of clinical symptoms. The capacity of low doses of X-rays to suppress inflammatory responses is a significant new concept for treatment COVID-19 pneumonitis. Low dose whole lung irradiation may be a potential solution in the present time. International research organization and the International Geriatric Radiotherapy Group (http://www.igrg.org) proposed a simple and practical protocol for Low dose whole lung irradiation to allow participation of all countries in the world regardless of their resources and made available to the whole world community for treatment COVID-19 pneumonitis.


Dose-Response ◽  
2020 ◽  
Vol 18 (4) ◽  
pp. 155932582096261
Author(s):  
Zhuo Wang ◽  
Ming-Yue Lv ◽  
Yao-Xiong Huang

Background: We aimed to reveal if low dose X-rays would induce harmful or beneficial effect or dual response on biological cells and whether there are conditions the radiation can enhance gene transfer efficiency and promote cell growth but without damage to the cells. Method: A systematic study was performed on the effects of Kilo-V and Mega-V X-rays on the cell morphology, viability, membrane permeability, DNA damage, and gene transfection of 293 T and CHO cells. Results: The Kilo-V X-rays of very low doses from 0.01 to 0.04 Gray in principle didn’t induce any significant change in cell morphology, growth, membrane permeability, and cause DNA damage. The Mega-V X-ray had a damage threshold between 1.0 and 1.5 Gray. The 0.25 Gray Mega-V-X-ray could promote cell growth and gene transfer, while the 1.5 Gray Mega-V X-ray damaged cells. Conclusion: The very low dose of KV X-rays is safe to cells, while the effects of Mega-V-X-rays are dose-dependent. Mega-V-X-rays with a dose higher than the damage threshold would be harmful, that between 1.0 -1.5 Gray can evoke dual effects, whereas 0.25 Gray MV X-ray is beneficial for both cell growth and gene transfer, thus would be suitable for radiation-enhanced gene transfection.


Dose-Response ◽  
2020 ◽  
Vol 18 (3) ◽  
pp. 155932582095954 ◽  
Author(s):  
Paul A. Oakley ◽  
Deed E. Harrison

All too often the family physician, orthopedic surgeon, dentist or chiropractor is met with radiophobic concerns about X-ray imaging in the clinical setting. These concerns, however, are unwarranted fears based on common but ill-informed and perpetuated ideology versus current understanding of the effects of low-dose radiation exposures. Themes of X-ray hesitancy come in 3 forms: 1. All radiation exposures are harmful (i.e. carcinogenic); 2. Radiation exposures are cumulative; 3. Children are more susceptible to radiation. Herein we address these concerns and find that low-dose radiation activates the body’s adaptive responses and leads to reduced cancers. Low-dose radiation is not cumulative as long as enough time (e.g. 24 hrs) passes prior to a repeated exposure, and any damage is repaired, removed, or eliminated. Children have more active immune systems; the literature shows children are no more affected than adults by radiation exposures. Medical X-rays present a small, insignificant addition to background radiation exposure that is not likely to cause harm. Doctors and patients alike should be better informed of the lack of risks from diagnostic radiation and the decision to image should rely on the best evidence, unique needs of the patient, and the expertise of the physician—not radiophobia.


2017 ◽  
Vol 73 (a2) ◽  
pp. C1027-C1027
Author(s):  
Go Ueno ◽  
Atsuhiro Shimada ◽  
Eiki Yamashita ◽  
Kazuya Hasegawa ◽  
Takashi Kumasaka ◽  
...  

1935 ◽  
Vol 31 (3-4) ◽  
pp. 452-463
Author(s):  
D. E. Goldstein ◽  
N. E. Sidorov

As is known, the issues of clarifying the diagnosis of diseases of the female genital area with the help of contrast agents have been dealt with almost from the earliest period of the use of X-rays in medicine; however, due to the strong irritant effect on the mucous membrane of the proposed contrast agents, or due to the weakness of the shadows given by them in the picture, these substances were left.


2017 ◽  
Vol 58 (1) ◽  
pp. 33-40 ◽  
Author(s):  
Norie Kanzaki ◽  
Takahiro Kataoka ◽  
Reo Etani ◽  
Kaori Sasaoka ◽  
Akihiro Kanagawa ◽  
...  

Abstract In our previous studies, we found that low-dose radiation inhibits oxidative stress–induced diseases due to increased antioxidants. Although these effects of low-dose radiation were demonstrated, further research was needed to clarify the effects. However, the analysis of oxidative stress is challenging, especially that of low levels of oxidative stress, because antioxidative substances are intricately involved. Thus, we proposed an approach for analysing oxidative liver damage via use of a self-organizing map (SOM)—a novel and comprehensive technique for evaluating hepatic and antioxidative function. Mice were treated with radon inhalation, irradiated with X-rays, or subjected to intraperitoneal injection of alcohol. We evaluated the oxidative damage levels in the liver from the SOM results for hepatic function and antioxidative substances. The results showed that the effects of low-dose irradiation (radon inhalation at a concentration of up to 2000 Bq/m3, or X-irradiation at a dose of up to 2.0 Gy) were comparable with the effect of alcohol administration at 0.5 g/kg bodyweight. Analysis using the SOM to discriminate small changes was made possible by its ability to ‘learn’ to adapt to unexpected changes. Moreover, when using a spherical SOM, the method comprehensively examined liver damage by radon, X-ray, and alcohol. We found that the types of liver damage caused by radon, X-rays, and alcohol have different characteristics. Therefore, our approaches would be useful as a method for evaluating oxidative liver damage caused by radon, X-rays and alcohol.


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