scholarly journals LABORATORY INDICATORS OF DIABETIC POLYNEUROPATHY

2019 ◽  
Vol 19 (1S) ◽  
pp. 112-114
Author(s):  
T V Stepanova ◽  
E B Popyhova ◽  
A N Ivanov

This study is devoted to diabetic polyneuropathy (DPN) - one of the common complications of diabetes mellitus (DM). The possibilities of laboratory diagnosis of this condition are shown. The purpose of this study was to examine the pathogenetic and diagnostic significance of certain neurospecific proteins and cytokines in DPN. The analysis of the literature data on the possibility of using neurospecific proteins and some cytokines in patients with diabetes as markers of neural tissue damage has been carried out.

Author(s):  
Abdullaev R.N. ◽  

The number of patients with diabetes mellitus in the Andijan region who were registered according to endocrinologists from 2000 to 2015 increased almost fourfold from 26,000 to more than 110,000 in 2016 (14). This also shows that the number of patients with various purulent-necrotic complications of diabetes mellitus also increases proportionally, in addition, there is an increase in patients with severe purulent-septic complications of these processes, with widespread, deep purulent-necrotic fasciitis [3]. Of patients in the department of surgical infection of the ASMI clinic, patients with purulent-necrotic complications of diabetes mellitus account for almost 78%, which indicates a significant increase in the number of these patients. This tendency continues and goes up every year. According to the WHO, by 2030 every 15 people will have diabetes, and by 2050 this figure will be equal to every 6 people.


2019 ◽  
Vol 14 (03) ◽  
pp. 180-192
Author(s):  
Philipp H. Baldia ◽  
Nikolaus Marx ◽  
Katharina A. Schütt

AbstractDiabetes mellitus is a very important comorbidity in patients with heart failure, as the common presence of both diseases significantly worsens the prognosis of patients. In order to improve the outcome of these patients, it is essential to diagnose both diseases at an early stage and to treat them in accordance with guidelines. In particular, a differentiated medication plays a crucial role. The therapy of heart failure does not differ in patients with diabetes and patients without diabetes. In the treatment of diabetes mellitus, however, it is very important to choose substances that have a positive effect on the cardiovascular outcome of patients. First-line treatment of diabetes in patients with cardiovascular diseases should be metformin, followed by a SGLT-2 inhibitor or GLP-1 receptor agonist with proven cardiac benefit. A rigorous adjustment of risk factors according to current guidelines reduces cardiovascular mortality and hospitalization rates. Glitazones and saxagliptin are associated with increased hospitalization rates and should be avoided in heart failure.


2021 ◽  
Vol 15 (10) ◽  
pp. 3170-3172
Author(s):  
Ayesha Masood ◽  
Sana Rehman ◽  
Imran Joher ◽  
Mazhar Ali Bhutto

Aim: This descriptive cross-sectional study was conducted to assess individual information about diabetes complications in patients with diabetes from questionnaires, and to find a relationship of this information to educational attainment and other sociodemographic profiles. Place and duration: Medical Department of Sharif Medical College, Lahore from January 2021 to June 2021. Methods: A total of 192 patients were enrolled in the study. People older than 16 years and who understand the query guidelines well were selected. All subjects answered the questionnaires given voluntarily and safely. The complete questionnaire was accessible in English language but was carefully translated to the official Pakistani language (Urdu). The enquiries were intended to evaluate how they knew about the diabetes mellitus complications and what those complications were. We use the SPSS 21.0 for data input and analysis. Chi-square test was applied for variables comparison. Results: We institute in this study that 94 people (48.9%) knew that the major impediment of diabetes is heart disease when blood sugar was not properly controlled, trailed by kidney disease (10.4%), and hypertension (7.8%), Eye Disease (2.6%) and cerebrovascular disease 32(16.6%). Regrettably, responsiveness was found about the presence of peripheral neurological problems, diabetic foot disease and unexpected bereavement was found in 1(0.5%) case only. Each of the subjects were inquired if they were concerned about serious complications of diabetes. Conclusions: There was statistical difference in any of the parameters (individual education, residence, monthly income, occupation, family history) depending on the degree of anxiety. The parameters were statistically significant. Further development of diabetes education programs, such as the use of the media and participation in national education programs, can improve the awareness of self-regulation of diabetes, which may decrease the mortality and morbidity of patients with diabetes. Keywords: Diabetic complications, anxiety.


2009 ◽  
Vol 278 (1-2) ◽  
pp. 41-43 ◽  
Author(s):  
Eleftherios Stamboulis ◽  
Konstantinos Voumvourakis ◽  
Athina Andrikopoulou ◽  
Georgios Koutsis ◽  
Nicholas Tentolouris ◽  
...  

Author(s):  
Huseyn Elcin ◽  

Diabetes mellitus is still a very common disease in the world and affects the daily lives of patients negatively. Diabetes is also known to be associated with neurological diseases such as peripheral nerve diseases, stroke and dementia. Among these, the most common disease is a peripheral nerve disease, and it has been reported that poor diabetic control increases the risk of development and can be prevented by education of the patients. Vascular dementia is more common in patients with diabetes than Alzheimer's disease, and it is thought that cerebrovascular diseases may berelated to cognitive impairment in diabetes. Although the mechanisms by which diabetes affects the brain are not clearly revealed, it is thought that changes in vascular structure, insulin resistance, glucose toxicity, oxidative stress, accumulation of glycation end products, hypoglycemic episodes and amyloid metabolism are effective.The aim of this article is to describe the neurological complications of diabetes and to emphasize the importance of patient education, good diabetes control and early diagnosis in preventing these complications.


2021 ◽  
pp. 97-101
Author(s):  
O.S. Krotova ◽  
L.A. Khvorova ◽  
A.I. Piyanzin

The paper deals with the problem of diabetic polyneuropathy diagnosing. This is one of the earliest and most dangerous complications of diabetes among children and adolescents. The research aims to develop models for diagnosing diabetic polyneuropathy in children and adolescents based on various medical data. The developed models will make it possible to diagnose a complication without using neurophysiological research methods. Therefore, the proposed models can be used in small medical and obstetrical stations in rural areas as well as a support system for making medical decisions. In the course of the study, a review and analysis of scientific publications of domestic and foreign scientists on the topic of the research are carried out. A large set of textual medical data is processed, then a database is created, features are analyzed, and a model is developed to reveal the presence of diabetic polyneuropathy in children and adolescents with type 1 diabetes mellitus. The achieved quality of the classification model allows us to assert that machine learning methods can be used to find hidden dependencies in the development and course of complications of diabetes mellitus.


2020 ◽  
Vol 22 (2) ◽  
pp. 45-49
Author(s):  
G. A. Batrac ◽  
◽  
N. F. Metelkina ◽  
A. N. Brodovskaya ◽  
E. A. Andrianova ◽  
...  

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