scholarly journals Peculiarties of catecholamines exchange in children with febrile convulsions

1997 ◽  
Vol XXIX (1-2) ◽  
pp. 50-52
Author(s):  
V. I. Guzeva ◽  
М. V. Kovelenova ◽  
М. Y. Sharf
Keyword(s):  
Functional State ◽  
Clinical Information ◽  
Febrile Seizures ◽  
Additional Increase ◽  
Febrile Convulsions ◽  
Prognostic Criteria ◽  
Adrenal System

Excretion of catecholamines indiumal urine of 75 children with febrile convulsionns has been studied. It has been revealed that functional state of sympathetic adrenal system in children with febrile convulsions is characterized by a number of peculiarities. They include an increase of adrenaline and norepinephrine. In the case of transformation of febrile into afebrile seizures additional increase of dopamine excretion is observed. Thats why hypersecretion of the three mentioned amines is estimated as prognostically unfavourable factor of the course of febrile convulsions. According to our findings, progression of seizures in sleeping state is also prognostically unfavourable symptom of the course of febrile seizures. The obtained biochemical ringings together with clinical information can serve as prognostic criteria in solving the problem of variations of the course of febrile convulsions.

Febrile Convulsions, by J. Gordon Millichap, M.D., M.R.C.P. New York: The Macmillan Company, 1968, 239 pp., $7.95

PEDIATRICS ◽  
1968 ◽  
Vol 42 (2) ◽  
pp. 381-382
Author(s):  
Randolph K. Byers
Keyword(s):  
New York ◽  
Relevant Literature ◽  
Febrile Seizures ◽  
Cerebral Injury ◽  
Extensive Review ◽  
Cerebral Disease ◽  
Febrile Convulsions ◽  
The Individual ◽  
The Brain ◽  
Made In

This rather modest-looking monograph deals not only with the large experiences of the author in relation to febrile seizures, but also presents an extensive review of the modern relevant literature (266 references in the bibliography). The most useful point made in the book, it seems to me, is that febrile convulsions are just that: i.e., convulsions coinciding with fever, the result of illness not directly involving the brain or its meninges. Such a seizure may be an isolated occurrence in the life of the individual, or it may recur a few times with fever; it may be the first sign of idiopathic chronic epilepsy, or it may be evidence of more or less apparent cerebral injury of a static sort; or, it may be the presenting symptom heralding progressive cerebral disease.

Inter-Illness Prophylaxis in Febrile Convulsions

PEDIATRICS ◽  
1968 ◽  
Vol 42 (6) ◽  
pp. 1012-1012
Author(s):  
John P. Curran
Keyword(s):  
Febrile Illness ◽  
Febrile Seizures ◽  
Febrile Convulsions ◽  
Intermittent Administration

In his review of Febrile Conculsions by Dr. J . Gordon Millichap, in the August 1968 issue of Pediatrics, Dr. Randolph K. Byers briefly deals with the question of continuous or "inter-illness" prophylaxis versus the intermittent administration of anti-convulsant medication at the onset of a febrile illness. This is certainly one of the most difficult decisions facing the pediatrician confronted with a child who has experienced one or more "febrile" seizures. Too often, it seems to me, this subject generates heated polemics, highlighted by the expression of extreme views of equal rigidity, leaving the busy practitioner draped over a therapeutic barrel.

The functional state of pituitary-adrenal system (PAS) on patients with multiple sclerosis

1995 ◽  
Vol 56-63 ◽  
pp. 40-40
Author(s):  
E. Korneva ◽  
E. Fomicheva ◽  
E. Shkhinek ◽  
N. Chernigovskaya
Keyword(s):  
Multiple Sclerosis ◽  
Functional State ◽  
Adrenal System

scholarly journals A study of febrile seizures in children in relation to iron deficiency anemia

2017 ◽  
Vol 4 (5) ◽  
pp. 1599
Author(s):  
Gautam Shah ◽  
Ritesh Parmar
Keyword(s):  
Risk Factor ◽  
Iron Deficiency ◽  
Sample Size ◽  
Iron Deficiency Anemia ◽  
Odds Ratio ◽  
Febrile Convulsion ◽  
Febrile Seizures ◽  
Deficiency Anemia ◽  
Large Sample Size ◽  
Febrile Convulsions

Background: Febrile seizures are the most common cause of convulsions in children between 6 months to 5 years, occurring in 2-5% of children. Iron deficiency is postulated as a risk factor for febrile seizures in children and it is an easily correctable condition. The objective of the study was to study the clinical profile and risk factors of febrile convulsions and to establish an association between febrile seizure and iron deficiency anemia.Methods: The study was carried out in Department of Pediatrics, Dhiraj General Hospital, Piparia, a tertiary care teaching hospital. 34 cases and 34 controls were included in the study. Controls were children of same age group presenting with short febrile illness but without any seizures. Febrile seizures were defined according to the AAP (American Academy of Pediatrics) criteria. Iron deficiency was diagnosed by hematologic investigations of haemoglobin value < 11 g/dl, MCV <70 fL and RDW > 15.6%.Results: Iron deficiency anemia was present in 23.52% (8/34) of cases as compared to 17.64% (6/34) in the control group. Odds ratio was 1.436 (95% CI 0.439-4.669, p value 0.549), which suggest there is no significant association of iron deficiency anemia with febrile convulsions. Subgroup analysis for association of iron deficiency anemia with simple febrile convulsion cases showed Odds ratio of 1.11 (95% CI 0.298-4.138), which suggests there is poor association of iron deficiency anemia with simple febrile convulsions. Subgroup analysis for association of iron deficiency anemia with complex febrile convulsion cases showed Odds ratio of 2.809 (95% CI 0.521-15.041), which suggests there is poor association of iron deficiency anemia with complex febrile convulsions. Wide confidence interval indicates less sample size. Study with large sample size is required for reliable interpretation.Conclusions:The study reveals iron deficiency anemia is not a significant risk factor in children presenting with febrile seizures. Further study with large sample size is required. 

scholarly journals Association between serum zinc level and simple febrile seizures in children: a hospital-based study

2018 ◽  
Vol 6 (9) ◽  
pp. 3116
Author(s):  
Najmus Saqib ◽  
Mahvish Qazi
Keyword(s):  
Hospital Admissions ◽  
Serum Zinc ◽  
Febrile Seizures ◽  
Zinc Level ◽  
Serum Zinc Level ◽  
Chi Square ◽  
Febrile Convulsions ◽  
Female Ratio ◽  
Zinc Levels ◽  
Serum Zinc Levels

Background: Febrile seizures are the most common cause of convulsions in children and a frequent cause of emergency hospital admissions. There are different hypothesis about neurotransmitters and trace element (such as zinc) changes in cerebrospinal fluid and serum, which can have a role in pathogenesis of febrile convulsions. Hence we want to study this association in our set up. Objectives was to study the association between serum zinc levels and febrile seizures in childern in our set up.Methods: This hospital based, prospective case control study was done in SKIMS Soura Srinagar, Kashmir (J and K), India for one-year period from August 2015 to July 2016. A total of 100 children aged 6 months to 6 years admitted in the hospital presenting with febrile seizures after fulfilling our inclusion and exclusion criteria were enrolled for the study. Informed consent was taken from their attendants and classified into 2 groups of 50 each. Patients with history of simple febrile seizures were taken as cases and those with fever without seizures as controls. A detailed history was taken, and complete physical examination was done on the patients and recorded on a precoded and pretested proforma. Blood was collected within 12 hours of admission and serum zinc levels were estimated. For statistical analysis, SPSS 17 program using t-test was employed. Chi-square test was performed to compare proportion between 2 or more discrete variables. P<0.05 was considered statistically significant.Results: Out of 100 children enrolled, male to female ratio was 1.63:1. Majority of the children were between 6 to 12 months (36%). The clinical presentation comprised of mainly non localized fevers majority of which had clinical evidence to suggest viral etiology (60%), followed by ARI (20%), ASOM (10%), UTI (6%) and bronchiolitis (4%). Mean serum zinc level in cases was 30.96±7.93ugm/dl and in controls it was 35.95±9.25ugm/dl. Serum zinc level was found significantly low in cases of simple febrile seizures as compared to controls (P<0.05).Conclusions: This study reveals that there is positive correlation between low serum zinc levels and febrile convulsions.

Functional state and stress periods of cardiovascular and sympathetic-adrenal systems in students throughout the academic year

1993 ◽  
Vol 74 (1) ◽  
pp. 14-18
Author(s):  
F. G. Sitdikov ◽  
M. V. Shaikhelislamova
Keyword(s):  
Functional State ◽  
Cardiac Rhythm ◽  
Physical Load ◽  
Statistical Characteristics ◽  
Training Period ◽  
Adaptation Process ◽  
Adrenal System ◽  
Pedagogical Institute ◽  
Academic Year ◽  
Functional Stress

The dynamics of a functional state of cardiovascular and sympathetic adrenal systems in students aged 1719 years throughout the academic year in the first, second and third УДК 616.921.5-06-037 course of the Pedagogical Institute is studied. The adaptation process of students is shown to be accompanied by stress periods in the functional state of cardiovascular and sympathetic adrenal systems. The response of the systems under study to the dosed physical load varies according to their functioning intensity. The character of correlative relations between hormonal and mediative links of sympathetic adrenal system and statistical characteristics of the cardiac rhythm depends on the training period and may serve as a criterion of the functional stress of the students organism.

Etiological evaluation of convulsions in children between 1 month to 5 years of age

2017 ◽  
Vol 4 (5) ◽  
pp. 1811 ◽  
Author(s):  
Bharathi Mamillapalli ◽  
Penchalaiah A.
Keyword(s):  
Viral Encephalitis ◽  
Febrile Seizures ◽  
Age Group ◽  
Older Children ◽  
Pyogenic Meningitis ◽  
Febrile Convulsions ◽  
Common Cause ◽  
Detailed History ◽  
Csf Analysis ◽  
Underlying Pathology

Background: Convulsions are the most common pediatric neurological disorder worldwide. The incidence is highest in children younger than 3 years of age with a decreasing frequency in older children. The different causes of seizures are febrile convulsions, CNS infections, neurologic or developmental, metabolic, traumatic or vascular, idiopathic or epilepsy, oncologic. The objective of our study is to find out the various etiologies of convulsions in children between 1 month to 5 years of age.Methods: 200 consecutive cases admitted to the hospital with convulsions in this particular age group were studied by detailed history, thorough examination and stepwise investigations including blood counts, CSF analysis, EEG and neuroimaging studies.Results: The most common cause for seizures in our study was febrile seizures (34.5%). Hypocalcemic seizures were the predominant cause (13%) between 1 month to 1 year of age. Other causes included viral encephalitis (20%), pyogenic meningitis (11%), TB meningitis (8.5%), epilepsy (8%), hypoglycemia (2%), neurocysticercosis (1%), head injury (1%) late HDN (0.5%). Cerebral palsy, mental retardation syndromes with developmental delay and epilepsy constituted 5.5% of the cases.Conclusions: Convulsions in children can be due to various underlying pathology. A detailed history, thorough examination and certain investigations helps to recognize the cause for the convulsions and can be treated accordingly.  

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