Clinicoepidemiological features of tick-borne encephalitis course in Perm krai
Objective. The incidence rate of tick-borne encephalitis in Perm Krai annually exceeds that in the Russian Federation by several times, and therefore, the aim of the study was to reveal the clinical and epidemiological characteristics of the course of infection. Materials and methods. A continuous retrospective clinical and laboratory survey including 314 adult patients admitted to the Perm Regional Clinical Infectious Diseases Hospital in 2014-2019 was carried out. Results. The following features were revealed: the disease is diagnosed more often in persons over 41 years old, infection mainly occurs when visiting the forest and park areas. That is why, it is necessary to reduce the number of infection carriers. In every fifth patient, the disease is characterized by the development of an inapparent form, as well as mixed infection in association with pathogens circulating in ticks in the territory of Western Ural ticks. Conclusions. In 45.9 % of cases, the infection has a moderate and severe course, involving not only meninges but also the brain substances into the pathological process that requires early diagnosis and timely adequate therapy.