scholarly journals A new way to optimize primary prevention of bleeding from varicose veins of esophagus

2021 ◽  
Vol 38 (2) ◽  
pp. 88-94
Author(s):  
Vadim N. Budarev

Objective. To establish the possibility of optimization of drug prevention of bleeding from varicose veins of the esophagus based on the influence of meteorological factors on the development of the disease. Materials and methods. The results of examination and treatment of 86 patients diagnosed bleeding from varicose veins of the esophagus, who were treated at the Emergency Hospital of Ryazan in 2016-2018, were analyzed. Results. A significant dependence of the incidence of bleeding from varicose veins of the esophagus on meteorological factors, in particular, on changes in atmospheric pressure, was revealed. Based on the analysis of the weather data archive, the safest periods for temporary interruption of the courses of drug primary prevention were established. Conclusions. A break in the course of primary drug prevention of bleeding from varicose veins of the esophagus, necessary to increase its effectiveness, will be the safest in February and July.

2021 ◽  
Vol 9 (3) ◽  
pp. 425-432
Author(s):  
A.V. Fedoseyev ◽  
◽  
V.N. Budarev ◽  

BACKGROUND: The problem of liver cirrhosis and associated bleedings from the varicose veins of the esophagus, unfortunately, remains highly relevant for Russia. Undoubtedly, it is important to identify factors that provoke an episode of bleeding. From a practical point of view, the most interesting ones are those that have an easily detectable nature and the maximum possible predictability. One of these factors, which is constantly varying throughout the year, is meteorological conditions. AIM: To evaluate the influence of meteorological factors on the occurrence of bleeding from varicose veins of the esophagus and the possibility of using this information to improve the schemes of primary prevention. MATERIALS AND METHODS: The material for the study was the results of examination and treatment of 86 patients hospitalized in 2016–2018 at the Emergency Hospital of Ryazan with a diagnosis of bleeding from esophageal varices. All these patients underwent fibroesophago-gastroduodenoscopy upon admission. The analysis of meteorological observations for 2016–2018 was carried out based on information from archived summaries of weather data. The results obtained were statistically processed using a standard set of programs. RESULTS: When analyzing the number of hospitalizations of patients with bleeding from varicose veins of the esophagus in different months of the year, a pronounced unevenness of admissions is revealed, the coefficient of variability is 53.65%. After excluding extreme values from the calculations, it was found that the incidence of the pathology increases in spring and autumn, decreases in summer and winter. The maximum incidence occurs in April and September, and the minimum in July and February. To determine the effect on patients of specific meteorological factors, a meteorological profile for a number of months was created from the archived weather data. In the course of statistical processing of the data, it was found that the only meteorological factor demonstrating a stable strong direct correlation with the number of hospitalizations of patients with bleeding from varicose veins of the esophagus (Pearson's correlation coefficient 0.9449) is the average atmospheric pressure gradient. This fact proves the ability of sudden changes in atmospheric pressure to provoke episodes of bleeding from the veins of the esophagus. CONCLUSIONS: When planning a course of primary pharmacological prevention of bleeding emerging the varicose veins of the esophagus, it is necessary to take into account the morbidity peaks occurring in April and September, as well as the ability of sudden changes of the atmospheric pressure to trigger the bleeding episodes.


Author(s):  
Hermes Ulises Ramirez-Sanchez ◽  
Alma Delia Ortiz-Bañuelos ◽  
Aida Lucia Fajardo-Montiel

Meteorological factors such as temperature, humidity, atmospheric pressure, wind speed and direction are associated with the dispersion of the SARS-CoV-2 virus through aerosols, particles <5μm are suspended in the air being infective at least three hours and dispersing from eight to ten meters. It has been shown that a 10-minute conversation, an infected person produces up to 6000 aerosol particles, which remain in the air from minutes to hours, depending on the prevailing weather conditions. Objective: To establish the correlation between meteorological variables, confirmed cases and deaths from COVID-19 in the 3 most important cities of Mexico. Methodology: A retrospective ecological study was conducted to evaluate the correlation of meteorological factors with COVID-19 cases and deaths in three Mexican cities. Results: The correlations between health and meteorological variables show that in the CDMX the meteorological variables that best correlate with the health variables are Temperature (T), Dew Point (DP), Wind speed (WS), Atmospheric Pressure (AP) and Relative Humidity (RH) in that order. In the ZMG are T, WS, RH, DP and AP; and in the ZMM are RH, WS, DP, T and AP. Conclusions In the 3 Metropolitan Areas showed that the meteorological factors that best correlate with the confirmed cases and deaths from COVID-19 are the T, RH; however, the correlation coefficients are low, so their association with health variables is less than other factors such as social distancing, hand washing, use of antibacterial gel and use of masks.


2012 ◽  
Vol 2012 ◽  
pp. 1-9 ◽  
Author(s):  
Haixiang Zang ◽  
Qingshan Xu ◽  
Pengwei Du ◽  
Katsuhiro Ichiyanagi

A modified typical meteorological year (TMY) method is proposed for generating TMY from practical measured weather data. A total of eleven weather indices and novel assigned weighting factors are applied in the processing of forming the TMY database. TMYs of 35 cities in China are generated based on the latest and accurate measured weather data (dry bulb temperature, relative humidity, wind velocity, atmospheric pressure, and daily global solar radiation) in the period of 1994–2010. The TMY data and typical solar radiation data are also investigated and analyzed in this paper, which are important in the utilizations of solar energy systems.


2013 ◽  
Vol 142 (7) ◽  
pp. 1384-1392 ◽  
Author(s):  
J. Y. C. CHAN ◽  
H. L. LIN ◽  
L. W. TIAN

SUMMARYVaricella accounts for substantial morbidities and remains a public health issue worldwide, especially in children. Little is known about the effect of meteorological variables on varicella infection risk for children. This study described the epidemiology of paediatric varicella notifications in Hong Kong from 2004 to 2010, and explored the association between paediatric varicella notifications in children aged <18 years and various meteorological factors using a time-stratified case-crossover model, with adjustment of potential confounding factors. The analysis found that daily mean temperature, atmospheric pressure and Southern Oscillation Index (SOI) were positively associated with paediatric varicella notifications. We found that an interquartile range (IQR) increase in temperature (8·38°C) at lag 1 day, a 9·50 hPa increase in atmospheric pressure for the current day, and a 21·91 unit increase in SOI for the current day may lead to an increase in daily cases of 5·19% [95% confidence interval (CI) 1·90–8·58], 5·77% (95% CI 3·01–8·61), and 4·32% (95% CI 2·98–5·68), respectively. An IQR increase in daily relative humidity (by 11·96%) was associated with a decrease in daily paediatric varicella (−2·79%, 95% CI −3·84 to −1·73). These findings suggest that meteorological factors might be important predictors of paediatric varicella infection in Hong Kong.


PeerJ ◽  
2020 ◽  
Vol 8 ◽  
pp. e8626 ◽  
Author(s):  
Wei Su ◽  
Ti Liu ◽  
Xingyi Geng ◽  
Guoliang Yang

Background Influenza is a disease under surveillance worldwide with different seasonal patterns in temperate and tropical regions. Previous studies have conducted modeling of influenza seasonality using climate variables. This study aimed to identify potential meteorological factors that are associated with influenza seasonality in Jinan, China. Methods Data from three influenza sentinel hospitals and respective climate factors (average temperature, relatively humidity (RH), absolute humidity (AH), sunshine duration, accumulated rainfall and speed of wind), from 2013 to 2016, were collected. Statistical and wavelet analyses were used to explore the epidemiological characteristics of influenza virus and its potential association with climate factors. Results The dynamic of influenza was characterized by annual cycle, with remarkable winter epidemic peaks from December to February. Spearman’s correlation and wavelet coherence analysis illuminated that temperature, AH and atmospheric pressure were main influencing factors. Multiple wavelet coherence analysis showed that temperature and atmospheric pressure might be the main influencing factors of influenza virus A(H3N2) and influenza virus B, whereas temperature and AH might best shape the seasonality of influenza virus A(H1N1)pdm09. During the epidemic season, the prevalence of influenza virus lagged behind the change of temperature by 1–8 weeks and atmospheric pressure by 0.5–3 weeks for different influenza viruses. Conclusion Climate factors were significantly associated with influenza seasonality in Jinan during the influenza epidemic season and the optional time for influenza vaccination is before November. These finding should be considered in influenza planning of control and prevention.


Elem Sci Anth ◽  
2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Yingquan Li ◽  
Baowei Zhao ◽  
Kaixiang Duan ◽  
Juexian Cai ◽  
Wujiang Niu ◽  
...  

PM2.5 and its bound metals pose a serious threat to human health. Understanding their contamination characteristics and source could provide implication for controlling their spreading and ensuring air quality. In this article, 1,600 of PM2.5 samples were collected from 5 urban sites in Lanzhou, China. The contamination characteristics of PM2.5, its relationship with meteorological factors, and the source of its bound metals were studied based on multiple linear regression analysis, enrichment factor (EF), principal component analysis and correlation analysis. The outcomes show that the PM2.5 concentrations in winter (0.117 mg·m–3) and spring (0.083 mg·m–3) are higher than those in summer (0.043 mg·m–3) and autumn (0.048 mg·m–3). The influence degree of meteorological factors on PM2.5 concentration is in the order of wind speed &gt; atmospheric pressure &gt; temperature &gt; humidity. The major source of Fe and Cu in PM2.5 is construction dust, Pb and As is industrial, and Hg is coal combustion. In addition, Cd, V, Co, and Mn are mainly derived from dust produced by weathering of soil or rock. In general, the spatiotemporal distribution of PM2.5 and its bound metals are different, which is closely related to geographical location, source, and meteorological factors. The results in this article could provide support for the scientific formulation to prevent air pollution in Lanzhou.


2021 ◽  
Vol 100 (12) ◽  
pp. 1350-1358
Author(s):  
Natalia M. Kolyagina ◽  
Tat'jana A. Berezhnova ◽  
Nikolaj P. Mamchik ◽  
Oleg V. Klepikov ◽  
Sergej A. Yeprintsev

Introduction. The impact of weather factors on the occurrence of exacerbations of diseases in meteodependent people is currently one of the actively studied problems of medicine. The aim of the study was to identify the relationship between exacerbations of diseases of the cardiovascular system with the meteorological situation to substantiate the need for preventive and informational work with meteodependent patients. Material and research methods. The study used daily data on the number of patients with cardiovascular diseases seeking medical care at Voronezh City Polyclinic No. 18 and daily information on weather conditions for 2018. The ratio of the average number of cases of medical assistance requests on days unfavourable for meteorological factors to the average number of cases of medical assistance requests per day during the year was calculated. Using software (Statistica Base V6.1), a correlation analysis of the relationship between the number of medical requests and meteorological factors was carried out. Results. It has been established that the appealability of patients with cardiovascular diseases for medical care on days unfavourable for meteorological factors is 1.1-2.0 times higher than the average annual indicator. The most informative characteristic of the six meteorological indicators taken into account in the study (average daily, minimum, maximum ambient air temperature; temperature drops by more than eight °C per day; atmospheric pressure; atmospheric pressure drops by 12 mm Hg per day or more) is a sharp drop in atmospheric pressure during the day, with which statistically significant (p <0.05) correlates the number of cases of patients with cardiovascular diseases seeking medical help. Conclusion. In medical institutions providing primary health care, it is advisable to single out separate groups of patients with meteorological dependence for dynamic observation and conduct information work with them to mitigate the severity of the course of diseases of the cardiovascular system on days unfavourable according to meteorological indicators.


2018 ◽  
Vol 8 (2) ◽  
pp. 342-347
Author(s):  
O. I. Fedorova ◽  
Ya. V. Lastochkina ◽  
A. E Maltseva

<p>The theories developed to explain the beginning of labor are usually considered outside the possible exogenous influence. In the literature, there are prerequisites for the study of the impact of meteorological factors on the initiation of delivery. The paper presents data on the dependence of the birth rate on meteorological environmental factors (atmospheric pressure, its gradient, temperature and humidity, wind speed) in a temperate continental climate of Western Siberia (Barnaul). The data recorded during 1998 (1,154 data) and within the climatic seasons are analyzed. For the purpose of verification of the received regularities, the repeated analysis is carried out on the material of data of 2014 (2145 data) on the basis that unlike a number of years which divided 1998 and 2014, environmental factors were the closest and typical for Barnaul climate. Conclusions were made on the results of the two replications based on these 1998 and 2014. With the help of dispersion analysis, it is shown that the key factor affecting the rate of delivery is the daily drop in atmospheric pressure in the direction of its reduction. Peculiarities of influence of meteorological factors on the frequency of births in different climatic seasons of the year. In particular, it was found that in the winter climatic period the number of births is most affected by meteorological factors, which include air temperature, atmospheric pressure, baric trend, air humidity. Possible mechanisms of observed phenomena are analyzed. It is assumed that one of the possible mechanisms of influence on the initiation of labor can be stressful corticotrophin-releasing secretion of hypothalamic factors, which, connected to the placental hormone, which is considered the "molecular clock" of pregnancy, its concentration increases and exceeds a certain threshold acts as a trigger to run the process of delivery ( Stefano et al., 2015). The second, the most probable factor influencing childbirth may be short-term changes in atmospheric pressure: it is possible the direct mechanical action of external barometric shifts on the volume of internal closed air-containing cavities, in particular, gas bubbles in the intestine, the swelling of which, when the atmospheric pressure decreases, can increase the pressure in the fetal bubble.</p>


2018 ◽  
Vol 24 (1) ◽  
pp. 15
Author(s):  
Ae. Kh. Samsonyan ◽  
I. A. Kurganov ◽  
D. Yu. Bogdanov ◽  
S. I. Emelianov ◽  
R. A. Bashirov ◽  
...  

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