scholarly journals Treatment of pediatric patients with lower leg deformities associated with physeal arrest: analysis of 28 cases

2017 ◽  
Vol 5 (4) ◽  
pp. 38-47
Author(s):  
Viktor A. Vilensky ◽  
Andrey A. Pozdeev ◽  
Timur F. Zubairov ◽  
Ekaterina A. Zakharyan
Keyword(s):  
External Fixation ◽  
Growth Plate ◽  
Deformity Correction ◽  
Limb Length Discrepancy ◽  
Lower Leg ◽  
Computer Assisted ◽  
Mechanical Axis Deviation ◽  
Group I ◽  
Group Ii ◽  
Healthy Part

Aim. To retrospectively analyze the results of two treatment methods for lower leg deformities associated with partial growth arrest. Materials and methods. Group I comprised 15 children who underwent osteotomy, acute overcorrection, and external fixation by Ilizarov with subsequent lengthening of the segment. Group II comprised 13 patients who underwent epiphysiodesis of the healthy part of the growth plate by drilling, osteotomy with external fixation by use of an Ortho-SUV Frame, and subsequent gradual deformity correction and lengthening. Results. In group I, overcorrection of varus deformities by mechanical axis deviation (MAD) was 18.28 ± 5.25 mm, overcorrection by mechanical medial proximal tibial angle (mMPTA) was 14.86 ± 4.45°, and overcorrection by mechanical lateral distal tibial angle (mLDTA) was 12.85 ± 3.02°. Overcorrection of valgus deformities according to MAD was 15.12 ± 8.28 mm, overcorrection by mMPTA was 10.38 ± 2.77°, and overcorrection by mLDTA was 7.5 ± 3.9°. Recurrence of the deformity was observed in 11 (73%) cases (range, 5–16 months). In group II, the accuracy of correction (AC) in varus deformities for MAD was 98% and 94% for mMPTA and mLDTA. For valgus deformities, AC for MAD was 90% and 96% for mMPTA and mLDTA. The AC for anatomical proximal posterior tibial angle and anatomical anterior distal tibial angle was 96% for procurvation deformities and that for recurvation deformities was 92%. Deformity recurrence was observed in only one case within 6 months after frame removal. In 2 cases, repeat limb length discrepancy correction surgeries were performed. Conclusion. Use of epiphysiodesis of the healthy portion of the growth plate in combination with osteotomy, computer-assisted external fixation with subsequent gradual deformity correction, and lengthening in patients with deformities associated with partial physeal arrest significantly decreased the number of deformity recurrences.

Efficacy of Computer-Assisted Management of Respiratory Failure in Neonates

PEDIATRICS ◽  
1986 ◽  
Vol 78 (1) ◽  
pp. 139-143 ◽  
Author(s):  
Waldemar A. Carlo ◽  
Lucia Pacifico ◽  
Robert L. Chatburn ◽  
Avroy A. Fanaroff
Keyword(s):  
Respiratory Failure ◽  
Computer Program ◽  
Computer Assisted ◽  
Blood Gas ◽  
Arterial Blood Gas ◽  
Group Iii ◽  
Arterial Blood ◽  
Group I ◽  
Group Ii ◽  
Assisted Management

We modified an algorithm for mechanical ventilation of infants with respiratory distress syndrome to create an interactive user-friendly computer program. To determine the effectiveness of this computer program, we evaluated the correction of deranged arterial blood gases in three groups of neonates: group I, treated before the introduction of the computer into the nursery; group II, managed by pediatric residents with the guidance of the computer program; group III, treated after the introduction of the computer into the nursery but managed without consideration of the computer output. Arterial blood gas values improved more frequently in the neonates managed with computer consultation (group II, 65/75, 87%) than in both control groups (group I, 37/57, 65%, P < .005; and group III, 46/63, 73%, P < .05). Furthermore, increases in ventilatory support in the presence of normal arterial blood gas values occurred only in patients managed without computer guidance. In a teaching institution, more effective care of neonates with respiratory failure may be facilitated by computer-assisted management of mechanical ventilators.

scholarly journals The role of external osteosynthesis in treatment of unstable pelvic osseous injuries

2019 ◽  
Vol 86 (5) ◽  
pp. 48-53
Author(s):  
N. L. Аnkin ◽  
L. N. Аnkin ◽  
T. M. Petryk ◽  
V. А. Ladyka
Keyword(s):  
External Fixation ◽  
Pelvic Ring ◽  
Fixation Method ◽  
Group Iii ◽  
Results Of Treatment ◽  
Pelvic Injuries ◽  
Group I ◽  
Joint Revision ◽  
Effect Of Treatment ◽  
Group Ii

Objective. To specify the role and indications for application of аpparatus of external fixation (АEF) in treatment of unstable pelvic osseous injuries (UPOI); to study up the advantages and faults of the external fixation method; to share the experience of treatment, using this procedure. Маterials and methods. There were 229 patients, suffering pelvic injuries, examined on the base of orthopedic-traumatological centre of Kyiv’s Regional Clinical Hospital in 2005 - 2017 yrs and distributed into three Groups. In Group I 143 (62.4%) injured persons were included, in whom external osteosynthesis played the function of temporary measures of fixation, in Group II - 27 (11.8%) patients, in whom while hospitalization a fracture was fixed, using AEF, аnd after stabilization of the state the posterior pelvis osteosynthesis and reposition was conducted, in Group III - 59 (25.8%) patients, who, using several indications, were definitely treated, applying the external fixation method only. Results. Excellent effect of treatment in Group I was registered in 23 (19.0%), a good one - in 58 (47.9%), satisfactory - in 32 (26.4%), poor - in 8 (6.6%) of 121 patients; in Group II - accordingly, - in 5 (20.8%), 11 (45.8%), 7 (29.2%) and 1 (4.2%) of 24 patients; in Group III - accordingly, in 4 (8.3%), 12 (25%), 23 (47.9%) and 9 (18.6%) of 48 patients. Conclusion. Best results of treatment of patients with unstable pelvic osseous injuries were obtained while applying the tactics of change from external fixation into internal one. On the first stage the pelvic ring fixation, using AEF, was performed, аnd after stabilization of a patient general status - internal osteosynthesis. Application of the internal osteosynthesis method permits to control and stabilize the reposition achieved, to conduct the sacro-ileal joint revision.

scholarly journals Improving postoperative radiographs for the parameter measurement of hexapod external fixator using an additional foot ring

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Yanshi Liu ◽  
Kai Liu ◽  
Feiyu Cai ◽  
Tao Zhang ◽  
Aihemaitijiang Yusufu
Keyword(s):  
External Fixation ◽  
Clinical Outcomes ◽  
External Fixator ◽  
Demographic Data ◽  
Deformity Correction ◽  
Parameter Measurement ◽  
Fixation Time ◽  
Trauma Patients ◽  
Group I ◽  
Outcomes Evaluation

Abstract Background It is challenging to determine the orthogonality of radiographs in daily clinical practice. The purpose of this study was to show the usefulness of an additional foot ring which might determine the orthogonality of postoperative radiographs for the parameter measurement of hexapod external fixator. Methods We retrospectively analyzed 81 consecutive trauma patients with tibial shaft fractures treated by the hexapod external fixator at our institution from September 2014 to July 2019. Starting in March 2016, the postoperative radiographs for parameter measurement were obtained under the control of an additional foot ring. The final data consisted of 47 patients in traditional radiographs (Group I) and 34 patients under the control of foot ring during the radiographic process (Group II). The demographic data, original postoperative deformities, residual deformities after final correction, number of repeated radiographs after the first postoperative radiographs, time to the satisfactory reduction achieved, and external fixation time in all patients were documented and analyzed. The Johner–Wruhs criteria were used for the final clinical outcomes evaluation at the last clinical visit. Results Satisfactory reduction and bone union were achieved in all patients. There were no statistical significances between the two groups in the demographic data, original postoperative deformities, residual deformities after final correction, external fixation time, and the final clinical outcomes (P > 0.05). The mean number of repeated radiographs after the first radiographs (1.4 times) and mean time to the satisfactory reduction achieved (3.3 days) in patients with an additional foot ring used were all less than those without foot ring (2.4 times, 5.3 days) (P < 0.05). Conclusions The additional foot ring is a practical device to ensure the orthogonality of postoperative radiographs for the hexapod external fixator parameter measurement. Radiation exposure, duration of deformity correction, and cost for patients might be reduced due to the less repeated radiographs with the wrong position.

Low density lipoprotein on poor quality mithun (Bos frontalis) semen preservation

2016 ◽  
Author(s):  
P. Perumal ◽  
S. K. Srivastava ◽  
K. K. Baruah ◽  
J. S. Rajoriya ◽  
N. Srivastava
Keyword(s):  
Density Lipoprotein ◽  
Egg Yolk ◽  
Cholesterol Content ◽  
Poor Quality ◽  
Computer Assisted ◽  
Low Density ◽  
Liquid Storage ◽  
Group I ◽  
Intracellular Enzymes ◽  
Group Ii

Low density lipoproteins (LDL) extracted from hens egg yolk (EY) has been studied over EY based extender for liquid storage of mithun semen with the objective to explore the use of LDL in place of EY. Physio-morphological attributes (PMAs) and mobility and velocity parameters were measured by computer assisted sperm analyser (CASA). Leakage of intracellular enzymes, activity of total antioxidants and lipid peroxidation following liquid storage (5oC) of mithun semen were studied. Fifty ejaculates were collected through transrectal massage method from matured mithun bulls and based on the mass activity and individual motility; the semen samples were splited into good and poor quality and diluted with the tris citrate glycerol (TCG) extender and were splited into three equal aliquots: Group I: Control, EY; Group II and Group III contained 8 and 10% LDL (w/v), respectively. PMAs, intracellular enzymatic leakage and biochemical profiles were evaluated at 5°C following 10hrs incubation. Result revealed a significant (p less than 0.05) improvement in PMAs, CASA parameters and cholesterol content of spermatozoa as well as reduction in leakage of intracellular enzymes, oxidative stress in Group II than control and other treatment group. It was concluded that addition of 8% LDL holds a clear advantage over EY or 10% LDL in liquid preservation of mithun semen.

scholarly journals From the foot-mouth reflex to the hand-mouth reflex a continuum of responses to Appendicular Compression

1997 ◽  
Vol 55 (2) ◽  
pp. 186-192 ◽  
Author(s):  
Fleming S. Pedroso ◽  
Newra T. Rotta
Keyword(s):  
Mouth Opening ◽  
First Trimester ◽  
Lower Leg ◽  
Psychomotor Development ◽  
Response Patterns ◽  
Normal Children ◽  
Group I ◽  
Group Ii ◽  
Stimulation Of

We studied the mouth opening response to appendicular compression in two groups of children. This study was performed with the intention of testing the semiologic role of the act of mouth opening following stimulation of various regions, based on the hand mouth reflex of Babkin. Group I was formed by 33 normal children who underwent monthly follow up assessments since birth; and group II consisted of 50 children older than 6 months of age, known to have a neurologic deficit and a neuro-psychomotor development equivalent to that of a child in the first trimester of life. We observed that the normal mouth opening response in group I was more pronounced following compression of the hand and forearm when compared to compression of the arm (p<0.001). This response could persist for as long as the first 6 months of life. We were not able to elicit a mouth opening response following compression of the lower limb in this group. Among children from group II, we observed mouth opening responses to stimulation of all limb segments. Within the upper limb, the response was more pronounced following compression of the hand in comparison to the forearm (p<0.01), and forearm in comparison to the proximal arm (p<0.01). Stimulation of the foot was more effective in eliciting a mouth opening response when compared to equivalent stimulation of the lower leg (p<0.05). However, there was no statistical difference when responses to stimulation of the lower leg and thigh were compared. The presence of the previously unreported foot-mouth response may serve as an indicator of central nervous system compromise and could be associated with a poorer prognosis. We believe that our observations of the specific foot-mouth response patterns may serve as a marker of early neuro-psychomotor development dysfunction during childhood.

scholarly journals COSTAL HUMPBACK RESECTION AS A FINAL STAGE OF IDIOPATHIC SCOLIOSIS SURGICAL TREATMENT

2006 ◽  
pp. 022-028
Author(s):  
Elena Vladimirovna Gubina ◽  
Mikhail Vitalyevich Mikhailovsky ◽  
Vladimir Nikolayevich Sarnadsky
Keyword(s):  
Surgical Treatment ◽  
Idiopathic Scoliosis ◽  
Vital Capacity ◽  
Deformity Correction ◽  
Spine Deformity ◽  
Curve Correction ◽  
Correction Loss ◽  
Group I ◽  
Curve Magnitude ◽  
Group Ii

Objective. To analyse results of multistage surgical treatment of idiopathic scoliosis including costal humpback resection. Material and Methods. From 1996 to 2005 twenty girls with idiopathic scoliosis underwent spine deformity correction with Harrington distraction rod with Drummond interspinous wires (Group I) or with Cotrel – Dubousset Horizon Instrumentation (Group II). The final long-dated stage after correction of deformity included the costal humpback resection at the convex side only. Radiologic and topographic examinations were performed, and lung vital capacity parameter was used for lung function assessment. Patients answered the Russian version of SRS-24 questionnaire after correction and at each follow-up examination. Results. In Group I the mean curvature was 81.7° ± 26.7° (range, 55–107°) before correction and 34.5° ± 13.1° after correction (primary curve correction 57.8 ± 14.1 %). Mean correction loss in dynamics before resection was 8°, after resection 4.3°. In Group II the primary curve magnitude before correction was 87.4° ± 27.1° (range, 48–126°), after correction 42.7° ± 16.9° (primary curve correction 51.9 ± 9.6 %). Average correction loss in dynamics before resection was 3.5°, after resection 2.4°. Spirometric findings presented the following dynamics: lung vital capacity before resection was 1980 ml with mean early postoperative decrease by 16.8 % and subsequent reversion to the preoperative level or increase to 2010 ml. According to the questionnaire survey 100 patients gave the consent for surgery. Conclusion. Costal humpback resection as a cosmetic intervention improves the patient’s assessment of spine deformity surgical correction result.

scholarly journals Sequence and organization of the Spodoptera exigua multicapsid nucleopolyhedrovirus genome

1999 ◽  
Vol 80 (12) ◽  
pp. 3289-3304 ◽  
Author(s):  
Wilfred F. J. IJkel ◽  
Elisabeth A. van Strien ◽  
Jacobus G. M. Heldens ◽  
René Broer ◽  
Douwe Zuidema ◽  
...  
Keyword(s):  
Spodoptera Exigua ◽  
Autographa Californica ◽  
Recent Common Ancestor ◽  
Computer Assisted ◽  
Glycoprotein Gene ◽  
Orgyia Pseudotsugata ◽  
Group I ◽  
Group Ii ◽  
Budded Virus ◽  
Assisted Analysis

The nucleotide sequence of the DNA genome of Spodoptera exigua multicapsid nucleopolyhedrovirus (SeMNPV), a group II NPV, was determined and analysed. The genome contains 135611 bp and has a G+C content of 44 mol%. Computer-assisted analysis revealed 139 ORFs of 150 nucleotides or larger; 103 have homologues in Autographa californica MNPV (AcMNPV) and a further 16 have homologues in other baculoviruses. Twenty ORFs are unique to SeMNPV. Major differences in SeMNPV gene content and arrangement were found compared with the group I NPVs AcMNPV, Bombyx mori (Bm) NPV and Orgyia pseudotsugata (Op) MNPV and the group II NPV Lymantria dispar (Ld) MNPV. Eighty-five ORFs were conserved among all five baculoviruses and are considered as candidate core baculovirus genes. Two putative p26 and odv-e66 homologues were identified in SeMNPV, each of which appeared to have been acquired independently and not by gene duplication. The SeMNPV genome lacks homologues of the major budded virus glycoprotein gene gp64, the immediate-early transactivator ie-2 and bro (baculovirus repeat ORF) genes that are found in AcMNPV, BmNPV, OpMNPV and LdMNPV. Gene parity analysis of baculovirus genomes suggests that SeMNPV and LdMNPV have a recent common ancestor and that they are more distantly related to the group I baculoviruses AcMNPV, BmNPV and OpMNPV. The orientation of the SeMNPV genome is reversed compared with the genomes of AcMNPV, BmNPV, OpMNPV and LdMNPV. However, the gene order in the ‘central’ part of baculovirus genomes is highly conserved and appears to be a key feature in the alignment of baculovirus genomes.

scholarly journals The sequence of the Helicoverpa armigera single nucleocapsid nucleopolyhedrovirus genome

2001 ◽  
Vol 82 (1) ◽  
pp. 241-257 ◽  
Author(s):  
Xinwen Chen ◽  
Wilfred F. J. IJkel ◽  
Renato Tarchini ◽  
Xiulian Sun ◽  
Hans Sandbrink ◽  
...  
Keyword(s):  
Helicoverpa Armigera ◽  
Amino Acid Identity ◽  
Computer Assisted ◽  
Structural Genomic ◽  
Orgyia Pseudotsugata ◽  
Group I ◽  
Helicoverpa Armígera ◽  
Group Ii ◽  
Budded Virus ◽  
Assisted Analysis

The nucleotide sequence of the Helicoverpa armigera single-nucleocapsid nucleopolyhedrovirus (HaSNPV) DNA genome was determined and analysed. The circular genome encompasses 131403 bp, has a G+C content of 39·1 mol% and contains five homologous regions with a unique pattern of repeats. Computer-assisted analysis revealed 135 putative ORFs of 150 nt or larger; 100 ORFs have homologues in Autographa californica multicapsid NPV (AcMNPV) and a further 15 ORFs have homologues in other baculoviruses such as Lymantria dispar MNPV (LdMNPV), Spodoptera exigua MNPV (SeMNPV) and Xestia c-nigrum granulovirus (XcGV). Twenty ORFs are unique to HaSNPV without homologues in GenBank. Among the six previously sequenced baculoviruses, AcMNPV, Bombyx mori NPV (BmNPV), Orgyia pseudotsugata MNPV (OpMNPV), SeMNPV, LdMNPV and XcGV, 65 ORFs are conserved and hence are considered as core baculovirus genes. The mean overall amino acid identity of HaSNPV ORFs was the highest with SeMNPV and LdMNPV homologues. Other than three ‘baculovirus repeat ORFs’ (bro) and two ‘inhibitor of apoptosis’ (iap) genes, no duplicated ORFs were found. A putative ORF showing similarity to poly(ADP-ribose) glycohydrolases (parg) was newly identified. The HaSNPV genome lacks a homologue of the major budded virus (BV) glycoprotein gene, gp64, of AcMNPV, BmNPV and OpMNPV. Instead, a homologue of SeMNPV ORF8, encoding the major BV envelope protein, has been identified. GeneParityPlot analysis suggests that HaSNPV, SeMNPV and LdMNPV (group II) have structural genomic features in common and are distinct from the group I NPVs and from the granuloviruses. Cluster alignment between group I and group II baculoviruses suggests that they have a common ancestor.

scholarly journals IMAGE-GUIDED SURGERY IN THE SPINE: NEURONAVIGATION VS. FLUOROSCOPY

2015 ◽  
Vol 14 (3) ◽  
pp. 181-185 ◽  
Author(s):  
Vinícius de Paula Guedes ◽  
Elisangela Ferrretti Manffra ◽  
Luiz Roberto Aguiar
Keyword(s):  
Blood Transfusion ◽  
Pedicle Screws ◽  
Operation Time ◽  
Computer Assisted Surgery ◽  
Accurate Method ◽  
Implantation Technique ◽  
Computer Assisted ◽  
Group I ◽  
Operative Complications ◽  
Group Ii

Objectives:To evaluate the accuracy and the operative complications of implanting pedicle screws in the thoracic and lumbar spine, using computer-assisted surgery compared to the implantation technique using fluoroscopy.Methods:A retrospective study was conducted at the Hospital Universitário Cajuru PUC-PR from January 2000 to January 2009. Two groups of patients undergoing implant pedicle screws were analyzed (n=80). Group I received implant pedicle screws through fluoroscopy technique and group II, through neuronavigation technique. The accuracy of positioning of pedicle screws was evaluated using rating scales.Results:The accuracy was higher in group II, where 77.5% of the screws were correctly positioned, whereas there were only 28.5% in group I (p=0.001). There was a reduction of 95% (CI: 80-97%) in the risk of screws misplacement in group II. The average operation time was 312.2±78.1 minutes in group I and 270.3±41.4 in group II (p=0.004). Blood transfusion was needed in 28 patients in group I and 10 patients in group II (p=0.005), resulting in 64% risk reduction of blood transfusion in group II. Eight patients in group I underwent revision surgery whereas only one patient in the group II, that is, 75% of surgical revision risk reduction.Conclusion:The implantation technique of pedicle screws using neuronavigation is a more accurate method and has less operative complications compared with the technique that uses fluoroscopy.

scholarly journals Rib deformity correction in children with pectus excavatum

2020 ◽  
Vol 27 (1) ◽  
pp. 6-10
Author(s):  
Sergey V. Kolesov ◽  
Dmitriy V. Khaspekov ◽  
Alexander A. Snetkov ◽  
Artur S. Sar ◽  
Arkadiy I. Kazmin
Keyword(s):  
Blood Loss ◽  
Minimally Invasive ◽  
Children And Adolescents ◽  
Pectus Excavatum ◽  
Randomized Study ◽  
Deformity Correction ◽  
Treatment Results ◽  
Group I ◽  
Duration Of Surgery ◽  
Group Ii

The article is devoted to a comparative analysis of the surgical treatment of pectus excavatum. A prospective, single-center, non-randomized study of the immediate results of the correction of pectus excavatum in children and adolescents is presented. Material and methods. The treatment results of 40 patients (27 men and 13 women) aged 3 to 18 years, operated between March 2005 and March 2016 were analyzed. All patients were examined according to the standard algorithm: chest MSCT, spirometry. All patients were divided into 2 groups. Group I patients operated on by the open resection method with plastic surgery of the costal arches (n=27). Group II patients operated with the use of minimally invasive technology according to NUSS, which does not provide for correction of deformation of costal arches (n=13). Results. In group II, significantly less blood loss was noted (35.7 ml versus 137 ml in group I, p0.05), shorter duration of surgery (230 min versus 27.5 min in group I, p0.05). It is worth noting the earlier discharge from the hospital in patients with minimally invasive correction of deformity. Conclusion. Minimally invasive thoracoplasty is an effective way to correct pectus excavatum in children and adolescents, which can significantly reduce the duration of surgery and intraoperative blood loss, is comparable in basic terms with reconstructive surgery, but inferior due to the lack of correction of deformation of the rib arches.

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