Small respiratory passages dysfunction in bronchial asthma

2020 ◽  
Vol 29 (6) ◽  
pp. 725-733
Author(s):  
O. Yu. Kytikova ◽  
M. V. Antonyuk ◽  
B. I. Gel'tser ◽  
E. E. Mineeva ◽  
T. A. Gvozdenko

The small respiratory passages dysfunction (SRPD) is found in the vast majority of patients with bronchial asthma (BA). The SRPD is currently recognized as the important pathogenetic feature of BA. The purpose of this review is to analyze the current scientific knowledge about the poorly studied aspects of the small respiratory passages (SRR) participation in the development of pathological process in BA, as well as the impact of small bronchial dysfunction on the clinical course, the exacerbation frequency and the disease control. The importance of SRPD diagnostics in BA patients for optimal and timely treatment is discussed. The modern methods of RPD pathology diagnostics are described; their informative use in the comparative study aspect is considered.

2016 ◽  
Vol 3 ◽  
pp. 368-372
Author(s):  
Krzysztof Wytrychowski ◽  
Anna Hans-Wytrychowska

Author(s):  
Pablo Beramendi

This article provides a partial but necessary review of the dominating themes, evolution, and pending tasks that await the comparative politics of federalism. The basic premise of this article is taken from rational choice institution-alism. The article fist delimits federalism as an institution, before it pays attention to the impact of federalism on democracy and the workings of the economy. An analysis of federalism as an endogenous institution is provided. The article also mentions a number of methodological considerations on the comparative study of the origins and consequences of federalism. It ends with a discussion of the various challenges that lie ahead of the field.


2011 ◽  
Vol 1 (7) ◽  
pp. 37
Author(s):  
W.A. Venis

Model tests have been carried out to obtain an insight into the magnitude of the wave-pressures in various situations. These tests showed, that sharp high pressure peaks occur in addition to the pressures caused by the reflecting of the waves, which pressures are quasi-static. As the structure can be compared with a multiple mass-spring system these pressure-peaks may cause the whole construction to vibrate. Wave-attack therefore can be expressed in terms of impact. Moreover, calculations revealed that the impact pressures were critical factors in determining the strength of the structure. So many model tests were carried out to determine the design and location of the sluices. These tests involved numerous water-levels discharges and waves. Regarding the pressure-peaks a comparative study was made in the model, which led to the structure being designed in such a way that the occurrence of critical impacts was reduced to an acceptable minimum. As it was impossible to avoid the occurrence of impact pressures entirely it remained necessary to determine a basic load for the structure that takes care of the impact pressures. As it has not yet appeared possible physically to determine a theoretical maximum for the impact pressures, it has to be borne in mind that there is a probability that each pressure measured will be exceeded. So this paper describes, how the cumulative frequency curve of the impacts for the case mentioned in 1.1 sub a, which served as a basis for determining the basic load was arrived at by a certain combination of laboratory and field observations. The data used for this purpose were a. Results of wave-impact measurements on a model of the sluices. This model, built in accordance with the results of the comparative study, was situated in the wind-flume of the "de Voorst" hydraulic laboratory. b. Wave height measurements in the Haringvliet during 1957 and 1958. c. Wind-speed measurements on board the lightship Qoeree, likewise during 1957 and 1958. d. Tidal registrations at Hellevoetsluis from 1920 to 1960. e. Wind-force data from the Hook of Holland, likewise from 1920 to 1960.


Author(s):  
Thomas Thaler

AbstractFlood risk management has developed a large inventory of potential actions to climate-related hazards. Within this wide array of measures, managed retreat of communities at risk is usually only taken into account if other strategies are ineffective or unavailable. Communities who are affected by managed retreat are confronted with radical changes in their livelihood. However, managed retreat is highly contested. The use of managed retreat includes not only the relocation of house owners but also has the challenge that it discriminates between landowners as some gain and others lose. Therefore, managed retreat raises issues of social justice. To mitigate the impact on land, compensation plays a crucial role in flood risk management. The level and kind of compensation varies between countries across the globe. In this paper, we compare two different policy compensation frameworks in two European countries: Austria and England. The comparative study shows how different compensation schemes affect social justice, both in terms of substantive distributions but also in terms of procedural justice.


Author(s):  
A. V. Protasov ◽  
N. P. Andreeva ◽  
A. M. Kostinovа

The review presents data on the role of respiratory agents in the pathogenesis of exacerbations of bronchial asthma and the impact of vaccination on the clinical course of the disease. The features of the formation of protective immunity in various immunization schemes are analyzed. In patients with bronchial asthma, the substantiation of the vaccination scheme with the advantage of priority administration of conjugated polysaccharide vaccine followed by the introduction of polysaccharide pneumococcal vaccine after 8 weeks is given. It was shown that vaccination against pneumococcal infection resulted in elimination from sputum S. pneumoniae. Influenza vaccination in patients with bronchial asthma reduced the frequency and duration of exacerbations. Combined vaccination against influenza and pneumococcal infections did not reduce the clinical and immunological effect.


Author(s):  
E. I Ostrovskiy ◽  
N. P Aleksandrova ◽  
V. I Karandashov ◽  
B. V Zubov

The article presents the results of the application of photochemotherapy for the combined rehabilitation treatment of the patients suffering from bronchial asthma. The assessment of the effectiveness and the impact of this treatment was made on the basis of changes of the indicators of blood rheology as one of the components of pathogenesis of this disease with due regard for the signs and symptoms characterizing the clinical course of this condition. It has been demonstrated that 74 patients presenting with bronchial asthma experienced the statistically significant restoration of the altered rheological parameters of blood and the general improvement of the clinical course of the disease under the influence of photochemotherapy in comparison with the results of the baseline treatment obtained in the remaining 42 patients. The effect of optical radiation of blue and red light on the clinical course of bronchial asthma was more pronounced than that of the conventional treatment. The two therapeutic modalities were virtually identical when evaluated based on the effectiveness criteria, but differed in terms of the mechanism of action on the body.


2021 ◽  
Vol VI (I) ◽  
pp. 35-40
Author(s):  
Muhammad Usman ◽  
Hafiz Aziz ur Rehman

The scientific knowledge and skills are the result of sophisticated methods where the liability of courts and investigation process has been increased during the last couple of decades. The use of technology and different other similar modern methods are helpful in the detection of offenders, and it is the revolutionary evaluation of investigation techniques. Since the offenders are also using different techniques for their criminal activities, so the use of technology is becoming more necessary for tracking the criminals. Both police and courts are using modern techniques of investigation with the use of modern technology for the detection of violent crimes and criminal activities. This paper examines the impact of modern technology on the investigation process and working mechanism of police and courts. Further, it elucidates the importance of modern technology and its impact upon the investigation process along with the outcome of criminal investigations.


Author(s):  
Nassima Dif ◽  
Zakaria Elberrichi

This chapter compares 4 variants of metaheuristics (RFA, EMVO, RPSO, and RBAT). The purpose is to test the impact of refinement on different types of metaheuristics (FA, MVO, PSO, and BAT). The refinement helps to enhance exploitation and to speed up the search process in multidimensional spaces. Moreover, it presents a powerful tool to solve different issues such as slow convergence. The different methods have been used for gene selection on 11 microarrays datasets to solve their various issues related to the presence of irrelevant genes. The obtained results reveal the positive impact of refinement on FA, MVO, and PSO, where all performances have been improved. On the other hand, this process harmed the BAT algorithm. The comparative study between the 4 variants highlights the efficiency of EMVO and FA in terms of precision and dimensionality reduction, respectively. Overall, this study suggests drawing attention to the choice of embedded metaheuristics in the refinement procedure, where powerful methods in exploration are recommended. Moreover, metaheuristics that risk form fast convergence are not advised.


Author(s):  
سيكو مارافا توري ◽  
عصام التجاني محمد إبراهيم

الملخّصيدرك المتتبع حقيقة حديث القرآن عن الأديان الأخرى بجانب بيانه الشافي للإسلام نفسه بين دفتيه. ولا ريب أن لهذه الظاهرة ثمراتها ومستلزماتها. أهمها ضرورة خوض المفسِّر وكثير من علماء المسلمين في الحديث عن الأديان، ومحاولة تأسي كثير من علماء المسلمين المختصين في علم الكلام والأديان بالمنهج القرآني لدى دراستهم للأديان؛ رغم إمكانية دراسة الأديان بمناهج أخرى غير المنهج القرآني، لأنّ المنهج يختلف باختلاف الهدف والغاية من الدراسة، ومنها النقاش العلمي حول أسبقية علماء المسلمين في دراسة الأديان: أيرجع ذلك إليهم أم إلى الغرب في العصر الحديث؟! وتبع ذلك إشكالية الموضوعية في دراسة الأديان. تسعى هذه الورقة إلى دراسة معالم منهج الإمام الرازي في دراسة النصرانية، ومدى تأثره في ذلك بالقرآن الكريم، وهل هو عين المناهج العلمية المعاصرة في دعوى دراسات الأديان المقارنة. وسيتبع الباحثان المنهج التحليلي في دراسة المنهج القرآني أولا بعد تتبع الآيات المعنية في ذلك، وفي استخراج وإبراز معالم منهج الرازي في دراسته للنصرانية. ومن أهم نتائج البحث أن ضرورة تفسير القرآن الكريم أدى إلى الخوض في دراسة دين آخر.      الكلمات المفتاحيّة: منهج القرآن الكريم، التفسير الموضوعي، الخطاب القرآني، دراسات قرآنية، النصرانية، الفخر الرازي.             AbstractThe Qur’an contains essential and significant accounts of other religions, providing enough room for Muslim scholars of Qur’anic interpretation. In these endeavours, Muslim scholars have adopted the approach of the Qur’an despite the availability of other methods. This is because methods differ according to the goals behind the study. Question has been raised as to who were first to engage in the study of other religions: Muslims or the western scholars in the modern age? There is also the question of objectivity in the study of religions. This paper examines hallmarks in the approach of ImÉm al-RÉzÊ toward the study of Christianity, and the extent it was influenced by the Qur’an, and whether it reflects contemporary scientific methods in the comparative study of religions. The researchers adopt the analytical method in the study of the Qur’anic approach after which it then extracts and highlights the hallmarks of Razi’s approach to the study of Christianity. As the paper concludes, there is a need to interpret the Qur’an’s description of other religions.Keywords: Qur’anic Methodology, Subjective Interpretation, Qur’anic Discourse, Qur’anic Studies, Christianity, Fakhr al-RÉzÊ.


2003 ◽  
Vol 7 (3) ◽  
pp. 312-331
Author(s):  
Kathleen Comerford

AbstractThis article explores several dioceses in Tuscany—Arezzo, Fiesole, Lucca, Montepulciano, Siena, and Volterra—in light of the foundation of diocesan seminaries, to determine if a new corps of priests was produced and if that corps instituted major changes. Historians refer to post-Tridentine attempts to strengthen the faith and power of groups and institutions by such processes as education as the parallel trends of confessionalism and confessionalization. Since these dioceses represent different economic, educational, and demographic levels of development, the comparative study of quantitative and qualitative measures in these regions addresses the impact of educational changes in the parish clergy in a significant cross-section of late-sixteenth and seventeenth-century Tuscany. Even in dioceses which were wealthy and which supported seminaries, the institutions had little influence, and therefore the slow and spotty improvements in the parishes and dioceses did not result in the confessionalization of the region, although limited confessionalism did occur.


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