scholarly journals Comparison analysis of decision tree and ensemble models in the classification of chronic kidney diseases

2020 ◽  
pp. 197-202
Author(s):  
Olawumi OLASUNKANMİ ◽  
Odunayo OLANLOYE ◽  
Abdulquadri ADEGBİJİ
Keyword(s):  
Decision Tree ◽  
Kidney Diseases ◽  
Comparison Analysis ◽  
Chronic Kidney Diseases ◽  
Ensemble Models

scholarly journals Ensemble Models for Classification of Coronary Artery Disease using Decision Trees

2020 ◽  
Vol 8 (6) ◽  
pp. 940-944
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Decision Tree ◽  
Cross Validation ◽  
Classification And Regression Tree ◽  
Data Set ◽  
Ensemble Models ◽  
Artery Disease ◽  
Fold Cross Validation

The foundation of data mining techniques using decision tree methods played a crucial role in the identification and classification of diseases. In the utilization of decision tree classifiers to develop the robust classifier for classification of Coronary Artery Disease data set namely Z-Alizadeh Sani and extension Z-Alizadeh Sani. We have used three decision tree techniques Random Forest (RF), Classification and Regression Tree (CART), J48 (C4.5) and made two ensemble models. These ensemble models have different combining rules like voting and stacking. The Voting Scheme model Vote (J48, RF, CART) and stacking Scheme model Stack (J48, RF, CART) have our proposed model. The findings are compared in individual and ensemble models classifier with 5-Fold Cross-Validation and 10-Fold Cross-Validation. The finding of the proposed ensemble models can be used in the detection and evaluation of Coronary Artery Disease (CAD).

scholarly journals Nephrotoxicity of Herbal Products in Europe—A Review of an Underestimated Problem of Nephrotoxicity of Herbal Products

2021 ◽  
Vol 22 (8) ◽  
pp. 4132
Author(s):  
Katarzyna Kiliś-Pstrusińska ◽  
Anna Wiela-Hojeńska
Keyword(s):  
Kidney Diseases ◽  
Herbal Medicines ◽  
Kidney Injury ◽  
Herbal Products ◽  
Chronic Kidney Diseases ◽  
European Origin ◽  
Synthetic Drugs ◽  
The Many ◽  
Pharmacologically Active ◽  
Traditional Chinese Herbal Medicines

Currently in Europe, despite the many advances in production technology of synthetic drugs, the interest in natural herbal medicines continues to increase. One of the reasons for their popular use is the assumption that natural equals safe. However, herbal medicines contain pharmacologically active ingredients, some of which have been associated with adverse effects. Kidneys are particularly susceptible to injury induced by toxins, including poisonous constituents from medicinal plants. The most recognized herb-induced kidney injury is aristolochic acid nephropathy connected with misuse of certain Traditional Chinese herbal medicines. Data concerning nephrotoxicity of plant species of European origin are scarce. Here, we critically review significant data of the nephrotoxicity of several plants used in European phytotherapy, including Artemisia herba-alba, Glycyrrhiza glabra, Euphorbia paralias, and Aloe). Causative mechanisms and factors predisposing to intoxications from the use of herbs are discussed. The basic intention of this review is to improve pharmacovigilance of herbal medicine, especially in patients with chronic kidney diseases.

scholarly journals Kidney organoid systems for studies of immune-mediated kidney diseases: challenges and opportunities

2021 ◽  
Author(s):  
Melissa C. Stein ◽  
Fabian Braun ◽  
Christian F. Krebs ◽  
Madeleine J. Bunders
Keyword(s):  
Kidney Diseases ◽  
Three Dimensional ◽  
Renal Tissue ◽  
Chronic Kidney Diseases ◽  
Immune Mediated ◽  
Primary Epithelial Cell ◽  
Challenges And Opportunities ◽  
Underlying Mechanisms ◽  
Global Population

AbstractAcute and chronic kidney diseases are major contributors to morbidity and mortality in the global population. Many nephropathies are considered to be immune-mediated with dysregulated immune responses playing an important role in the pathogenesis. At present, targeted approaches for many kidney diseases are still lacking, as the underlying mechanisms remain insufficiently understood. With the recent development of organoids—a three-dimensional, multicellular culture system, which recapitulates important aspects of human tissues—new opportunities to investigate interactions between renal cells and immune cells in the pathogenesis of kidney diseases arise. To date, kidney organoid systems, which reflect the structure and closer resemble critical aspects of the organ, have been established. Here, we highlight the recent advances in the development of kidney organoid models, including pluripotent stem cell-derived kidney organoids and primary epithelial cell-based tubuloids. The employment and further required advances of current organoid models are discussed to investigate the role of the immune system in renal tissue development, regeneration, and inflammation to identify targets for the development of novel therapeutic approaches of immune-mediated kidney diseases.

scholarly journals Decision Tree C 4.5 Algorithm for Classification of Poor Family Scholarship Recipients

2021 ◽  
Vol 1125 (1) ◽  
pp. 012048
Author(s):  
Y Kustiyahningsih ◽  
B K Khotimah ◽  
D R Anamisa ◽  
M Yusuf ◽  
T Rahayu ◽  
...  
Keyword(s):  
Decision Tree ◽  
Poor Family ◽  
Scholarship Recipients
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