scholarly journals In-vitro anti-oxidant studies on ethanolic extract of Alpinia galanga linn

2016 ◽  
pp. 1245-1248
Author(s):  
Subash K.R. ◽  
Bhanu G.
Keyword(s):  
Ethanolic Extract ◽  
Alpinia Galanga ◽  
Anti Oxidant

scholarly journals Evaluation of In Vitro Anti-Oxidant Activity of Mentha arvensis Linn in Memory Enhancing Study

2017 ◽  
Vol 9 (08) ◽  
Author(s):  
Nazima Ameen ◽  
Sabeeha Shafi
Keyword(s):  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Parkinson Disease ◽  
Ethanolic Extract ◽  
Phytochemical Analysis ◽  
Mentha Arvensis ◽  
Aerial Parts ◽  
Anti Oxidant ◽  
Memory Enhancing

The main objective of the study was to evaluate the in vitro anti-oxidant parameters for the study of memory enhancing activity of Mentha arvensis Linn closely related to Alzheimers disease. Mentha arvensisLinn is a plant commonly known as Pudina.It is used in our daily cuisines in India. The study included the aerial parts of Mentha arvensis belonging to family Lamiaceae. Two extracts were taken the aqueous and ethanolic extract. The phytochemical analysis of plant of Mentha arvensis Linn showed the presence of alkaloids, tannins,saponins, glycosides, terpenes, flavonoids, fats, carbohydrates, steroids and proteins.Oxidative compounds are responsible for causing many diseases like ischemic heart disease, Parkinson disease, hyperlipidemia, atherosclerosis and Alzhemers disease. In order to cure these diseases anti-oxidants are used. Keeping these facts in view, the anti-oxidant activity of Mentha arvensis Linn was evaluated in memory enhancing activity.

scholarly journals Evaluation of In-Vitro Antioxidant Activity of Root Bark Extracts of Ventilago Maderspatana Gaertn

2020 ◽  
Vol 11 (SPL4) ◽  
pp. 1636-1640
Author(s):  
Manish Deshmukh ◽  
Ashish Budhrani ◽  
Upendra Gandagule ◽  
Sanjay Nagdev ◽  
Mayur Bhurat ◽  
...  
Keyword(s):  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Ethanolic Extract ◽  
Bark Extract ◽  
Root Bark ◽  
Anti Oxidant ◽  
Biomedical Potential ◽  
Oxide Inhibition ◽  
In Vitro Antioxidant Activity

Ventilago maderspatana Gaertn. is a plant having enormous biomedical potential. It is a plant in the Indian system of medicine having a plethora of properties and applications and The root barks powder of Ventilago maderspatana Gaertn.  have many properties and applications like it are used as a stomachic, tonic, carminative, stimulant. It is also useful in the treatment of weakness and fever. For further investigations of activities like anti-oxidant activity, In-vitro  anti-oxidant studies were done on root bark extracts of Ventilago maderspatana Gaertn. (Family Rhamnaceae) by using standard methods like Lipid peroxidation Assay, Estimation of total anti-oxidant capacity (TAC), Hydroxyl radical scavenging activity, Nitric oxide inhibition radical activity by p-Nitroso dimethyl aniline method, and ABTS Radical scavenging method. The root barks of plant Ventilago maderspatana Gaertn. Were subjected to cold maceration process in 3-liter Round bottom flask using ethanol and distilled water and nature and yield was noted and stored at 40C in the refrigerator until further use and both the extracts were labelled as Ventilago maderspatana Gaertn. Root Bark aqueous (VMRBA) and Ventilago maderspatana Gaertn. Root Bark Ethanolic (VMRBE) for convenient identification. Ethanolic extract of Root Bark showed the more potent anti-oxidant activity than aqueous Root Bark extract of Ventilago maderspatana Gaertn.

scholarly journals Phytochemical characterization of the ethanolic extract of Kaempferia galanga rhizome for anti-oxidant activities by HPTLC and GCMS

2022 ◽  
Vol 8 (1) ◽  
Author(s):  
Flavius Phrangsngi Nonglang ◽  
Abhijeet Khale ◽  
Surya Bhan
Keyword(s):  
Gas Chromatography ◽  
High Performance ◽  
Freeze Drying ◽  
Ethanolic Extract ◽  
Dry Weight ◽  
Kaempferia Galanga ◽  
Anti Oxidant ◽  
Gas Chromatography Mass Spectroscopy ◽  
Layer Chromatography

Abstract Background The rhizome of Kaempferia galanga (K. galanga) was collected from Meghalaya, India, and its ethanolic extract was obtained by freeze-drying or lyophilization process, which was then assessed for its in vitro anti-oxidant activity and phytochemical characterization using high-performance thin-layer chromatography (HPTLC) and gas chromatography-mass spectroscopy (GCMS). Results In vitro anti-oxidant activity analysis shows an inhibitory concentration (IC50) value of 1.824 mg/mL and 0.307 mg/mL for, α, α-diphenyl-ρ-picrylhydrazyl (DPPH) and 2, 2′-azino-bis-3-ethylbenzothiazoline-6-sulfonic acid (ABTS) assays, respectively. Total polyphenol content (TPC) of 23.55 ± 0.5 mg gallic acid equivalent (GAE)/g dry weight of extract and total flavonoid content (TFC) of 100 ± 1.414 mg rutin equivalents (RE)/g dry weight of extract were found. High-performance thin-layer chromatography (HPTLC) analysis shows the best separation of bands at different retention factor (Rf) values, when employing the solvent system 2-butanol/1-propanol/water in the ratio of 3:1:1 (v/v/v). Gas chromatography-mass spectroscopy (GCMS) analysis confirms the presence and identification of various phytocompounds, with ethyl p-methoxycinnamate identified as the major active compound. Conclusion Freeze-dried ethanolic extract of K. galanga (rhizome) possesses anti-oxidant activity. Ethyl p-methoxycinnamate is present as the major bioactive component (about 94.87% of the total area composition), and since it has very important and diverse medicinal properties, a freeze-drying process (lyophilization) can be utilized for its isolation and extraction.

scholarly journals Anti-melanogenic and Anti-oxidant Activities of an Ethanolic Extract of Kummerowia striata and its active compounds, p-coumaric acid and quercetin

2018 ◽  
Author(s):  
Ju-Hyoung Park ◽  
Jae Yeon Lee ◽  
Young-Rak Cho ◽  
Eun-Kyung Ahn ◽  
Wonsik Jeong ◽  
...  
Keyword(s):  
Antioxidant Activities ◽  
Ethanolic Extract ◽  
Model Systems ◽  
Dependent Manner ◽  
Melanin Synthesis ◽  
Related Protein ◽  
Anti Oxidant ◽  
Kummerowia Striata ◽  
Tyrosinase Related Protein

Kummerowia striata is a traditional medicine used for the therapy of inflammation-related diseases. Herein, we investigated the anti-melanogenic and antioxidant activities of an ethanolic extract of K. striata (EKS) using a number of in vitro and cell culture model systems. The anti-melanogenic effect was assessed in B16F10 melanoma cells based on melanin synthesis and in vitro tyrosinase inhibitory activity and the anti-oxidant activity assays were performed using 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2ʹ-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS); EKS exhibited strong anti-oxidant activities in both the assays. The expression of tyrosinase, tyrosinase-related protein 1, tyrosinase-related protein 2, and microphthalmia-associated transcription factor was decreased in a dose-dependent manner at mRNA and protein levels upon treatment with EKS. Notably, EKS did not affect the cell viability at all the EKS concentrations used in this study, indicating that EKS-mediated inhibition of melanin synthesis is not accompanied with cytotoxicity. Collectively, our findings demonstrate, for the first time, that EKS possesses anti-melanogenic and anti-oxidant activities, and suggest that further evaluation and development of EKS as a functional supplement or cosmetic might be useful for skin whitening and for reduction wrinkles.

Phytochemical Screening and In Vitro Antioxidant Activity of Ethanolic Extract of Cassia occidentalis

2017 ◽  
Vol 9 (3) ◽  
Author(s):  
S. Srividya ◽  
G. Sridevi ◽  
A. G. Manimegalai
Keyword(s):  
Antioxidant Activity ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Ethanolic Extract ◽  
Phytochemical Analysis ◽  
Scavenging Activity ◽  
Cassia Occidentalis ◽  
Total Antioxidant ◽  
Anti Oxidant

The ethanolic extract of the leaves of Cassia occidentalis (Co) were subjected to phytochemical analysis by standard qualitative analysis and the invitro antioxidant activity was evaluated by determination of total antioxidant capacity, 1.1- diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity, hydrogen peroxide (H2O2) radical scavenging activity, superoxide scavenging activity and Ferric reducing anti oxidant potential (FRAP). The analyses revealed that the ethanolic extract of Co was able to efficiently scavenge the free radicals in a dose dependant manner. The results were compared with the standard antioxidant ascorbic acid. The results have shown that crude ethanolic extract of the leaves of Co showed excellent antioxidant activity due to the presence of bioactive compounds namely alkaloids, betacyanin, cardiac glycosides, coumarins, flavonoids, phenols, steroids, saponins, tannins, terpenoids, anthraquinones and emodins.

scholarly journals Anti-Inflammatory And Anti-Oxidant Activities Of Glochidion Daltonii Branch Extract

2018 ◽  
Vol 3 (2) ◽  
pp. 39
Author(s):  
Jintana Junlatat ◽  
Bungorn Sripanidkulchai
Keyword(s):  
Intraperitoneal Administration ◽  
Ethanolic Extract ◽  
Paw Edema ◽  
Sprague Dawley ◽  
Tropical Regions ◽  
Rat Paw Edema ◽  
Anti Oxidant ◽  
Anti Inflammatory

Background: Glochidion daltonii (MÜll. Arg.) Kurz, Euphorbiaceae family, is a native medicinal plant in tropical regions of Asia. In Thailand, it has traditionally been used for treating pain and mouth inflammation. Objective: This study aims to investigate the anti-inflammatory and anti-oxidant effects of G. daltonii ethanolic extract (GDE) both in vitro and in vivo. Method: The anti-inflammatory mechanism was examined in E.coli LPS-stimulated RAW264.7 cells by using semi-quantitative-reverse transcription-polymerase chain reaction and the potential anti-inflammatory effect of GDE was evaluated in Sprague-Dawley rat using carrageenan-induced rat paw edema method. In addition, DPPH assay was used for anti-oxidant evaluation. Result: The results showed that GDE at 0.063 - 0.250 mg/mL concentrations inhibited the expressions of tumor necrosis factor-α and interleukin-1β. Moreover, an intraperitoneal administration of GDE significantly reduced paw edema in rats. Furthermore, GDE showed high anti-oxidant property with IC50 values at 6.35 ± 0.28 µg/mL. Conclusion: The results support the traditionally use of GDE for treating inflammation.

scholarly journals Phytochemical screening & in-vitro evaluation of anti-inflammatory activity of clerodendrum indicum roots

2021 ◽  
pp. 140-143
Author(s):  
Sushma M ◽  
Lahari S ◽  
Mounika A ◽  
Sailaja K.E
Keyword(s):  
Ethanolic Extract ◽  
Inflammatory Activity ◽  
Phytochemical Screening ◽  
In Vitro Evaluation ◽  
Anti Cancer ◽  
The Family ◽  
Steroid Glycosides ◽  
Anti Oxidant ◽  
Anti Inflammatory

This study aims to extract the phytochemical constituents and in-vitro evaluation of   anti-inflammatory activity of roots of clerodendrum Indicum. Clerodendrum indicum (L.) kuntz. Commonly known as bharangi or chingari, belongs to the family verbenaceae. The plant is expectorant, stomachic, Anti-bronchitis, Anti-nociceptive, Anti-microbial, Anti-diarrheal, anti-oxidant and anti-cancer. Preliminary phytochemical screening revealed the presence of flavonoids, steroids, steroid glycosides, terpenoids etc. This study has taken with the Anti-inflammatory  activity and preliminary phytochemical screening on the clerodendrum indicum. In the present study, qualitative study of    the phytochemicals present in the sample was determined, Anti-inflammatory  activity  were carried out. On the premise of the prevailing study, the outcomes eventually concluded that the ethanolic extract of clerodendrum indicum own anti inflammatory pastime. This evaluation offers an concept that the compound of the plant clerodendrum indicum may be used as lead compound for designing robust pills which may be used for remedy of diverse diseases.

scholarly journals PRELIMINARY PHYTOCHEMICAL SCREENING AND TO EVALUATE ANTI-OXIDANT PROPERTY ON ROOT EXTRACT OF DILLENIA INDICA (ELEPHANT APPLE)

2019 ◽  
pp. 128-133
Author(s):  
BIDISHA BORDOLOI ◽  
SUMIT DAS
Keyword(s):  
Antioxidant Activity ◽  
Petroleum Ether ◽  
Reducing Power ◽  
Ethanolic Extract ◽  
Root Extract ◽  
Standard Drug ◽  
Antioxidants Activity ◽  
Dpph Method ◽  
Anti Oxidant

Objective: The objective of the present study was to carry out the presence of antioxidants activity on root extract of Dilleniaindica (Family-Dilleniaceae) which is believed to have the protective mechanisms in beneficial health effects. Methods: Considering its medicinal importance, the plant was chosen for extraction with various solvents such as petroleum ether, chloroform and ethanol which was taken into considerations to determine the phytochemicals analyses present in it. The extracts of the roots were evaluated for antioxidant activity by using different in vitro models like Reducing Power method, TBA Method and DPPH method at different doses (20,50,100,200,400μg/ml). The ic50 values of each extract on different activity were carried out. Results: The study shows that petroleum ether, chloroform and ethanolic extract of this plant showed potent antioxidant activity against the standard drug (Ascorbic acid). But chloroform extract of the roots shown most significant anti-oxidant activity as compared to petroleum ether and ethanol. Conclusion: The root part of the plant shows active anti-oxidant activity that can be consumed by mankind.

scholarly journals Extracts of Tectona grandis and Vernonia amygdalina have anti-Toxoplasma and pro-inflammatory properties in vitro

Parasite ◽  
2018 ◽  
Vol 25 ◽  
pp. 11 ◽  
Author(s):  
Mlatovi Dégbé ◽  
Françoise Debierre-Grockiego ◽  
Amivi Tété-Bénissan ◽  
Héloïse Débare ◽  
Kodjo Aklikokou ◽  
...  
Keyword(s):  
Plant Extracts ◽  
Mammalian Cells ◽  
Ethanolic Extract ◽  
Antigen Presenting Cells ◽  
Tectona Grandis ◽  
Vernonia Amygdalina ◽  
Phytochemical Content ◽  
Anti Oxidant ◽  
Antigen Presenting

Tectona grandis (teak) and Vernonia amygdalina (bitter leaf) are plants used in traditional medicine in West Africa. In this study, we tested ethanolic and hydro-ethanolic extracts of bark and leaves of T. grandis and ethanolic extract of leaves of V. amygdalina for their inhibitory effect on Toxoplasma gondii, a protozoan parasite responsible for toxoplasmosis. Ethanolic extract of V. amygdalina leaves had proportional contents of phenols, tannins, flavonoids, and polysaccharides. This extract presented the highest efficacy against T. gondii, the lowest cytotoxicity to mammalian cells, but moderate anti-oxidant activity compared to other plant extracts. Ethanolic extract of T. grandis bark also had elevated anti-T. gondii activity, low cytotoxicity on mammalian cells, and one of the highest anti-oxidant activities. However, the phytochemical content of this extract was not very different from the hydro-ethanolic extract, which had no anti-T. gondii activity. In addition, ethanolic extract of V. amygdalina leaves, but not of T. grandis bark, significantly increased the production of TNF-α and NO by antigen-presenting cells. Both extracts had the tendency to decrease expression of major histocompatibility complex molecules at the surface of antigen-presenting cells, while they did not modulate the percentage of apoptotic cells. A study of signalling pathways would help to determine the mechanisms of action of these plant extracts.

Sign in / Sign up

Export Citation Format

Share Document