scholarly journals Comparison of the treatment mediated changes in serum lipid profile of cases with metabolic syndrome treated with low dose atorvastatin versus the usual care group

2017 ◽  
Vol 6 (3) ◽  
pp. 624
Author(s):  
Shubhangam Sharma ◽  
Hemlata Verma ◽  
Anuradha Dubey
Keyword(s):  
Metabolic Syndrome ◽  
Usual Care ◽  
Lipid Profile ◽  
Serum Lipid ◽  
Low Dose ◽  
Tertiary Care ◽  
Cardiovascular Outcomes ◽  
Serum Lipid Profile ◽  
Group A ◽  
Group B

Background: Metabolic syndrome (MetS) is a constellation of cardiometabolic risk determinants comprising of obesity, insulin resistance, dyslipidaemia and hypertension. In view of the epidemic of metabolic syndrome, this prospective, comparative study done in OPD setting in a tertiary care centre of central India aimed at finding out the changes in lipid profile, a surrogate marker of cardiovascular morbidities on treatment with low dose atorvastatin versus the usual care group.Methods: Patients satisfying NCEP-ATPIII criteria for metabolic syndrome were divided into two groups. Group A received treatment with 20 mg Atorvastatin along with target driven treatment for hypertension and elevated glucose, as required. Group B received the same except for atorvastatin. Serum lipid profiles were recorded and changes were compared before and after study duration of 3 months. Also, cardiac events were kept track of during follow up.Results: At the end of study it was found that treatment mediated changes in the lipid profile were highly significant (p<0.001) and favourable in group A as compared to Group B. Also, lesser cardiovascular outcomes were observed in Group A patients.Conclusions: The study concludes that among patients with metabolic syndrome, those treated with statins benefitted more than those who did not take statin therapy. This benefit in the correction of serum lipid profile also translated in terms of decreased cardiovascular outcomes in Group A patients. Hence, low dose atorvastatin therapy provides a potential approach for treatment of patients with metabolic syndrome.

scholarly journals Study of serum lipid profile and magnesium in preeclampsia

2019 ◽  
Vol 8 (4) ◽  
pp. 1445
Author(s):  
Hymavathi K. Reddy ◽  
Vineela P. ◽  
Bhargavi M. Chowdary
Keyword(s):  
Lipid Profile ◽  
Serum Lipid ◽  
Serum Magnesium ◽  
Low Density Lipoprotein ◽  
Tertiary Care ◽  
Density Lipoprotein ◽  
Serum Lipid Profile ◽  
Low Density ◽  
Group A ◽  
Group B

Background: A comparative study of serum lipid profile and magnesium levels in normal pregnancy versus preeclampsia (PE).Methods: A prospective study done for 2 years (October 2014 to October 2016) in the Department of Obstetrics and Gynecology, Narayana medical college and hospital, a tertiary care centre, Nellore, Andhra Pradesh, India. A sample size of 200 pregnant women, recruited and divided into group A and B. group A being women with PE and group B is normal pregnant women.A10ml of venous blood was collected in the fasting state and serum collected from clotted blood to measure lipid profile, magnesium, Apo lipoprotein A-I and Apo lipoprotein B 100.Serum Lipid profile  measured by enzymatic method using commercially available kit Human (GmbH Germany) using humastar 600 chemistry analyzer (Human GmbH Germany). Serum magnesium measured by dye binding method using commercially available kit Human (GmbH Germany) using Humastar 600 chemistry analyzer (Human GmbH Germany). Serum ApoA-I and ApoB were measured by immune-turbidometry using commercial kits from Spinreact Spain. Urine albumin done by dipstick method.Results: Serum total cholesterol (TC), Triglyceride (TG), low density lipoprotein (LDL), very low-density lipoprotein (VLDL), Apo lipoprotein B 100 (Apo B100) were high and serum Magnesium, high density lipoprotein (HDL) and Apo lipoprotein A1(Apo A1) were low in the study group (group A) compared to controls (group B).Conclusions: Abnormal lipid profile (low HDL and increased TG concentration) and serum hypomagnesaemia may be contributing etiologies of preeclampsia, having good predictive value as a screening procedure for PE in high risk pregnant population.

scholarly journals A CLINICAL STUDY TO EVALUATE THE EFFICACY OF VAMANA KARMA IN THE MANAGEMENT OF DYSLIPIDEMIA

2018 ◽  
Vol 11 (12) ◽  
pp. 350
Author(s):  
Shipra Singh ◽  
Alok Kumar Srivastava
Keyword(s):  
Lipid Profile ◽  
Serum Lipid ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Biochemical Parameter ◽  
Serum Lipid Profile ◽  
Standard Drug ◽  
Safe Management ◽  
Group A ◽  
Group B

Objective: The aim of the present study is to evaluate the efficacy of Vamana karma in the management of dyslipidemia.Methods: Patients were selected from the OPD and IPD at the Department of Panchakarma, Hospital of Rishikul Campus, Uttarakhand Ayurved University, Haridwar. Patients in Group A will be administered with two sittings of Vamana procedure. In Group B, 20 patients will be treated with atorvastatin for 60 days in dose of 10 mg once daily after meals with water.Results: The overall assessment of the therapy was decided on the basis of improvement in biochemical parameter (serum lipid profile) by applying statistics. Vamana karma had statistically highly significant result in all the objective parameters except high-density lipoprotein [HDL].Conclusion: Thus, it can be concluded that dyslipidemia is a form of Kaphavikara specifically may be Medodushti in the form of Abaddha meda. Vamana karma is highly effective in correcting serum lipid profile except HDL and very low-density lipoprotein but have better effect than the standard drug in both of them. Vamana karma can be used for the effective and safe management of dyslipidemia.

scholarly journals Serum lipid profile as predictor of clinical outcome in pediatric patients with dengue infection at a tertiary care hospital

2019 ◽  
Vol 7 (1) ◽  
pp. 1
Author(s):  
Mohd. Saeed S. Siddiqui ◽  
Amruta Kailash Loya ◽  
Udaykumar Kanumala ◽  
Jagannath R. Kakade
Keyword(s):  
Lipid Profile ◽  
Serum Lipid ◽  
Tertiary Care Hospital ◽  
Dengue Infection ◽  
Tertiary Care ◽  
Serum Lipid Profile ◽  
Health Concern ◽  
Care Hospital ◽  
Disease Category ◽  
Dengue Disease

Background: Dengue is a serious mosquito-borne viral disease which in recent years has become a major international public health concern. Early detection of individuals at risk of developing severe forms of dengue could be possible with the identification of an ideal biomarker, which has been the focus of several research studies. Changes in lipoprotein profile during infection probably are primarily cytokine induced Interactions between microorganisms and lipoproteins occur in viral infections. There have been very few studies that address and elucidate a correlation between dengue fever severity and changes in the lipid profile.Methods: This study was conducted in paediatric patients with dengue infection of age group between 1 to 18 years MGM Medical College and Tertiary Care Hospital of Aurangabad City.Results: There was statistically significant association between TG (mg/dl) level and dengue disease category (DF vs DHS+DSS) among the patients. Overall the combine lipids were significantly predicting dengue disease category (DF, DHS and DSS). Serum lipids (triglycerides, LDL and cholesterol) among the patients significantly predict dengue disease category (DF, DHS and DSS). There was negative correlation between triglycerides level and HDL and hospital Stay which was found to be statistically significant.Conclusions: Reduced serum lipid profile can be used as a cost-effective laboratory investigation prompting a high suspicion of severe dengue infection especially in resource poor setting where serological tests may not be available.

scholarly journals The effects of low dose hormone therapy on serum lipid profile, glisemic control, thyroid hormones and androgen levels in postmenopausal women

2011 ◽  
Vol 8 (2) ◽  
pp. 125-133
Author(s):  
A Yasemin Karageyim Karsidag ◽  
Nevriye Alkan ◽  
Esra Esim Buyukbayrak ◽  
Bulent Kars ◽  
Meltem Pirimoglu ◽  
...  
Keyword(s):  
Thyroid Hormones ◽  
Hormone Therapy ◽  
Lipid Profile ◽  
Postmenopausal Women ◽  
Serum Lipid ◽  
Low Dose ◽  
Serum Lipid Profile ◽  
Androgen Levels

scholarly journals METABOLIC SYNDROME IN PREGNAT FEMALES PRESENTING IN A TERTIARY CARE HOSPITAL AND ITS IMPACT ON INCIDENCE OF PRE -TERM DELIVERY.

2021 ◽  
Vol 71 (3) ◽  
pp. 767-70
Author(s):  
Ayesha Imran ◽  
Umairah Yaqub ◽  
Wafa Aslam ◽  
Tehreem Yazdani ◽  
Zarmeen Khawar ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Preterm Delivery ◽  
Strong Association ◽  
Tertiary Care ◽  
Military Hospital ◽  
Care Hospital ◽  
Term Delivery ◽  
Active Labor ◽  
Group A ◽  
Group B

Objective: To find the association of preterm delivery with metabolic syndrome in females presenting in a tertiary care hospital.Study Design: Cohort study.Place and Duration of Study: Department of Obstetrics & Gynecology, Combined Military Hospital Kharian, from May 2020 to Oct 2020.Methodology: A total of 150 females fulfilling inclusion criteria were enrolled in the study which were divided into two equal groups ‘A’ and ‘B’. Group ‘A’ was with metabolic syndrome and group ‘B’ without it. These females were followed in OPD till active labor, assessed and followed till delivery of fetus. If delivery occurred before 37 weeks, then preterm delivery was labeled. All this information was recorded on a pre-designed proforma.Results: The risk for preterm delivery was 2.18 times higher in group ‘A’ as compared to group ‘B’. (Relative Risk = 2.18, CI (95%) 1.1529 - 4.12).Conclusion: There is a strong association of preterm delivery with metabolic syndrome in females.

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