scholarly journals Prescription Pattern In Hypertensive Patients In A Tertiary Care Teaching Hospital, Dhaka, Bangladesh

2018 ◽  
Vol 8 (2) ◽  
pp. 39-43
Author(s):  
Udoy Shankar Roy ◽  
Nazibur Rahman Khandaker ◽  
Saleh Uddin ◽  
Murshidur Rahman Khan ◽  
Nihar Ranjan Sarker
Keyword(s):  
Drug Utilization ◽  
Ace Inhibitors ◽  
Antihypertensive Drugs ◽  
Angiotensin Receptor Blockers ◽  
Tertiary Care ◽  
Essential Medicine ◽  
Fixed Dose ◽  
Drug Prescribing ◽  
Prescribing Pattern ◽  
Hypertensive Patients

Background: Irrational drug prescribing is a common practice globally; it results in increased morbidity, mortality & economic burden on society. Drug utilization studies are an important tool to promote rational prescribing.Aims & Objective: To study on drug prescribing pattern in hypertensive patients.Materials and Methods: A drug utilization study was conducted in hypertensive patients by the department of cardiology in OPD at Shaheed Suhrawardy Medical college hospital for 6 months. 645 prescriptions were evaluated for prescribing pattern by using WHO drug use indicators.Results: 645 prescriptions were analyzed. A total of 1828 drugs were prescribed. 697 (38.13%) antihypertensive, 243 (13.30%) anti diabetics, 174 (9.52%) non-steroidal anti-inflammatory drugs (NSAIDs), 154 (8.44%) statins, 114 (6.24%) thyroid hormone, 54 (2.95%) anti-anxiety/ antidepressants and 392(21.44%) miscellaneous drugs were prescribed. 697 antihypertensive drugs were prescribed. 234 (33.57%) angiotensin receptor blockers (ARBs), 117 (16.79%) angiotensin converting enzyme (ACE) inhibitors, 95 (13.63%) Beta blockers, 83 (11.91%) Calcium channel blockers 168 (24.10%) Fixed dose combinations (FDCs) of antihypertensive were included. 2.83 drugs were prescribed per prescription. 225 (32.28%) antihypertensive were prescribed from essential medicine list.Conclusion: Most commonly prescribed drugs were ARBs and ACE inhibitors. Rational prescribing requires consideration to dose and duration and interaction with other medications.J Shaheed Suhrawardy Med Coll, December 2016, Vol.8(2); 39-43

scholarly journals Prescribing Pattern of Anti-Hypertensive Drugs and Adherence to JNC VII Guideline

Proceedings ◽  
2018 ◽  
Vol 6 (1) ◽  
pp. 11
Author(s):  
Biswash Sapkota ◽  
Heamant Shrestha ◽  
Nischal Khatri ◽  
Krishna Shrestha
Keyword(s):  
Public Health ◽  
Drug Utilization ◽  
Antihypertensive Drugs ◽  
Angiotensin Receptor Blockers ◽  
Significant Risk ◽  
Health Concern ◽  
National Committee ◽  
Age Group ◽  
Prescribing Pattern ◽  
Hypertensive Patients

Introduction: Hypertension is an important public health concern because of its associated morbidity, mortality and economic impact on society. It is a significant risk factor for cardiovascular, cerebrovascular and renal complications. A number of national and international guidelines for the management of hypertension have been published. The Joint National Committee (JNC) in 2003 published a series of guidelines to recommend the appropriate antihypertensive therapy based on the best available evidence. Objectives: This drug utilization study was intended to find out the preferred drug group prescribed either alone or in combinations and their adherence to the JNC 7 guidelines. Materials and Methods: This was a prospective cross-sectional study. Drug utilization data on 100 hypertensive patients were collected from various hospitals in Nepal. The patients who received antihypertensive drugs during their treatment period in SPSS V. 16.0. The prescribed drugs were compared with JNC 7 guidelines. Results: It was found that 40% of patients were male and 60% were female. The largest subset of female hypertensive patients (45.0%) were in the age group of >60 years and a plurality of male hypertensive patients (45.0%) were in the age group of 40–60 years. It was found that 45% of the patients had Stage 1 hypertension, 32% of the patients were in prehypertension, 17% of the patients had Stage 2 hypertension. The most frequently prescribed antihypertensive drug regimens were angiotensin receptor blockers (ARBs) (32.44%), ARB + thiazide (15.94%), diuretics (11.59%), calcium channel blockers (CCBs) + beta blockers (9.42%) and CCBs (8.7%). Thirty-nine percent received monotherapy while the remaining 61% received combination therapy. Seventy-four percent of the total prescriptions followed JNC 7 guidelines. Conclusion: There is a need to follow official guidelines in managing hypertension as a chronic disease, since these guidelines are based on various clinical trials, and the successful attainment of a target BP in patients will be made much easier by implementing them. National health policymakers should consider the evaluation and treatment of hypertension as a right in the public health system for better outcomes in terms of morbidity and mortality from hypertension.

scholarly journals Prescribing Pattern of Antihypertensive Drugs in Hypertensive Patients with Non-Insulin Dependent Diabetes Mellitus at Tertiary Care Hospitals in Karachi Pakistan

2021 ◽  
pp. 107-112
Author(s):  
Syed Wajid Shah ◽  
Mirza Tasawer Baig ◽  
Syed Imran Ali ◽  
Qurratul ain Leghari ◽  
Aisha Jabeen ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Antihypertensive Drugs ◽  
Tertiary Care ◽  
Fixed Dose ◽  
Prescribing Pattern ◽  
Hypertensive Patients ◽  
Tertiary Care Hospitals

Introduction: Hypertension (HTN) is one of the most serious public health issues in the world, affecting around 1.4 billion people worldwide. HTN is becoming highly prevalent in Pakistan, about more than 33% of people over the age of 40 years suffering from the HTN. The illness burden is continuously growing due to the incorrect medicine prescriptions, a lack of education, and a lack of patient compliance. The existence of comorbidities such as Diabetes Mellitus (DM) should be properly considered while choosing an Antihypertensive medication. Similarly, the prescriptions of Oral Hypoglycemic agent’s appropriate consideration are essential. Oral hypoglycemic medications are divided into several categories. Physicians face a challenge in rationally selecting a regimen from a variety of classes, and the situation becomes more complicated when the patients have additional non-communicable illnesses, such as HTN. The combination therapy of ailments not only effects the patient`s economic status but also effects the quality of life. Objective: To study the prescribing pattern of Antihypertensive drugs in Hypertensive patients with Type 2 Diabetes Mellitus at Tertiary care hospitals in Karachi, Pakistan. Methods: A cross sectional study was undertaken for six months in medicine outpatient department at tertiary care hospitals of Karachi. The study population was observed for the prescribed pattern of Antihypertensive medicines by assessing the 300 prescriptions of Hypertensive patients with Type 2 Diabetes Mellitus. Statistical analysis was performed using SPSS version 20. Data was presented as frequencies and percentages. Results: The result revealed that the most commonly prescribed single antihypertensive drug was Enalapril 66 (22%) followed by Amlodipine 63(21%), Ramipril 57(19%), Diltiazem 33(11%), Lisinopril 21(7%) losartan k 6(2%), Nebivolol 6(2%), Bisoprolol 3(1%). Dual therapy included Ramipril and Nebivolol 1(0.33%) and Amlodipine+Valsartan 35 (11.67%), Amlodipine+Valsartan+HCTZ 9 (3%) were the antihypertensive drugs prescribed as fixed dose combinations. Conclusion:  The present study shows Enalapril belonging to Angiotensin Converting Enzyme Inhibitor (ACEI) class was frequently used as single Antihypertensive agent and Amlodipine+Valsartan belonging Calcium Channel Blockers (CCBs) and Angiotensin Receptor Blockers (ARBs) was the most frequently prescribed fixed dose combination while managing Hypertension of Hypertensive patients with Type 2 Diabetes Mellitus.

scholarly journals Prescription pattern and rationality of antihypertensive drugs in patients of type 2 diabetes with hypertension: a pilot study

2019 ◽  
Vol 7 (4) ◽  
pp. 982
Author(s):  
A. S. Bhore ◽  
Kalyani Khandare ◽  
K. A. Bansod
Keyword(s):  
Type 2 Diabetes ◽  
Antihypertensive Drugs ◽  
Angiotensin Receptor Blockers ◽  
Tertiary Care ◽  
Fixed Dose ◽  
Care Hospital ◽  
Cross Sectional Survey ◽  
Prescribing Pattern ◽  
Oral Antidiabetic Agents

Background: As presence of hypertension (HTN) in type 2 diabetes significantly increases risk of morbidity and mortality, its control with rational use of antihypertensives is essential. Authors performed this study to understand the current prescribing pattern of antihypertensives in patients of type 2 diabetes and their assess the rationality to recommendations of JNC-8 guidelines.Methods: Authors performed a cross sectional survey of prescription of diagnosed patients of diabetes with HTN at a tertiary care hospital. Prescription of patients attending medicine OPD were scanned. Data was collected over 2 month and analyzed with descriptive statistics.Results: In 76 patients analysed, mean age was 54.9±9.3 years and 51.3% were females. Insulin and oral antidiabetic agents were prescribed in 16 (21.1%) and 73 (96.1%) patients respectively. One, two, three and four antihypertensive drugs were prescribed in 44 (57.9%), 28 (36.8%), 3 (3.9%) and 1 (1.3%) patients respectively and 24 (31.6%) of them were fixed dose combinations. Among antihypertensives, angiotensin converting enzyme inhibitors (ACEIs), angiotensin receptor blockers (ARBs), thiazide diuretics, beta blockers (BBs) and calcium channel blockers (CCBs) were present in 29 (38.2%), 26 (34.2%), 22 (28.9%), 21 (27.6%) and 14 (18.4%) respectively. In individual drugs, ramipril (28.9%) was most common followed by telmisartan (26.3%), hydrochlorothiazide (26.3%), atenolol (16, 21.1%) and amlodipine (17.1%) were frequently prescribed. In adjuvant drugs, antiplatelet (52.6%) and statins (56.6%) were common. This pattern of prescription was as per the recommendations of recent JNC-8 guidelines for treatment of hypertension.Conclusions: ACEIs/ARB are the most preferred for HTN treatment in type 2 diabetes mellitus. Prescription of antihypertensives in our set up was rational as per JNC-8 recommendations.

scholarly journals Prescribing trends in respiratory tract infections in a tertiary care teaching hospital

2017 ◽  
Vol 5 (6) ◽  
pp. 2588 ◽  
Author(s):  
Mirza A. Beg ◽  
Shakti B. Dutta ◽  
Shalu Bawa ◽  
Amanjot Kaur ◽  
Subhash Vishal ◽  
...  
Keyword(s):  
Respiratory Tract ◽  
Drug Utilization ◽  
Respiratory Tract Infections ◽  
Tertiary Care ◽  
Essential Medicine ◽  
Fixed Dose ◽  
Utilization Pattern ◽  
Prescribing Pattern ◽  
Prescribing Trends ◽  
Tract Infections

Background: Respiratory tract infections are a major cause of morbidity and mortality in developing countries. Polypharmacy and irrational prescribing in respiratory diseases are common practice worldwide. Keeping in consideration this scenario, present study was undertaken to analyze the drug utilization pattern of respiratory tract infections.Methods: This drug utilization study was conducted by Pharmacology department at SGRRIM & HS to analyze drug utilization pattern of respiratory infections. A total of 585 prescriptions were collected from hospital and randomly evaluated for prescribing pattern using WHO drug indicators.Results: A total of 585 prescriptions were analyzed. Male:Female ratio was 1:0.77. Age wise distribution was done; 81(13.84%) 0-15 years, 54(9.23%) 16-30 years, 198(33.84%) 31-45 years, 75(12.82%) 46-60 years and 177(30.25%) patients belongs to >60 years of age group respectively. A total of 4869 drugs were prescribed, 2754(56.56%) antibiotics, 675(13.8%) bronchodilators, 630(12.93%) corticosteroids, 303(6.22%) antacids, 507(10.41%) in miscellaneous category respectively. 2562(52.61%) oral, 1491(30.62%) injectable and 816(16.75%) inhalational drugs were prescribed. Numbers of Fixed dose combinations were 645(13.24%). 8.32 drugs were prescribed per prescription. 2409(49.47%) drugs were prescribed from national essential medicine list 2015. 4320(88.72%) drugs were prescribed by their brand names.Conclusions: Irrational prescribing and polypharmacy was observed. The drug utilization studies are important tool to sensitize and increases awareness among physicians, which ultimately improves rational prescribing and patient care.

Evaluation of an outpatient department (OPD)-based prescribing pattern of fixed-dose combinations in a tertiary care institute in Central India

2020 ◽  
Vol 31 (3) ◽  
Author(s):  
Satish Chandel ◽  
Niket Rai ◽  
Sadashivam Balakrishnan ◽  
Ratinder Jhaj ◽  
Akash Vishwe ◽  
...  
Keyword(s):  
Descriptive Analysis ◽  
Tertiary Care ◽  
Essential Medicine ◽  
Central India ◽  
Fixed Dose ◽  
Medical Sciences ◽  
Prescribing Pattern ◽  
Prescribing Trends ◽  
Inflammatory Drugs ◽  
Male Patients

AbstractBackgroundFixed-dose combinations (FDCs) are being widely prescribed for the treatment of various disorders in India. However, not all FDCs are rational. To know the awareness of physicians in prescribing rational FDCs was the need of the hour in order to assess the prescribing trends and rationality of FDCs. Eventually, this will help to formulate the guideline for rational use of FDCs.MethodsThis was a prospective observational study conducted in All India Institute of Medical Sciences Bhopal, MP, India. Prescriptions were collected over a period of 2 months by the convenience sampling method from hospital pharmacy. The data were subjected to descriptive analysis using Microsoft Excel and Graph Pad Prism. Results were expressed in mean ± standard deviation (SD), percentages and 95% confidence interval.ResultsA total of 2496 drugs were prescribed in 1008 prescriptions, of which 945 (37.82%) were FDCs with an average of 0.93 ± 0.94 (mean ± SD) per prescription. Of 945, 67 (7.09%) were included in National List of Essential Medicine 2015 considered as rational. The number of prescriptions containing one or more FDCs was 629 (62.40%). FDCs were more frequently prescribed to male patients (54.92%) and in the age group of 18–30 years (33.44%). FDCs containing a proton pump inhibitor were prescribed most frequently (16.29%) followed by nonsteroidal anti-inflammatory drugs (13.96%) and multivitamins (7.83%).ConclusionsPrescribing irrational FDCs was very common, and hence there is an obvious need to update our prescribers about the irrationality of FDC and motivate them to develop a habit of rational prescribing.

ASSESSMENT OF DRUG PRESCRIBING PATTERN IN THE INPATIENT SURGERY DEPARTMENT AT A TERTIARY CARE TEACHING HOSPITAL USING WHO PRESCRIBING INDICATORS.

2020 ◽  
Vol 7 (10) ◽  
pp. 12-18
Keyword(s):  
Teaching Hospital ◽  
Tertiary Care ◽  
Essential Medicine ◽  
Drug Prescribing ◽  
Prescribing Pattern ◽  
Prescribing Indicators ◽  
Tertiary Care Teaching Hospital ◽  
Care Teaching ◽  
Inpatient Ward ◽  
Surgery Department

Background: Drug use is a tricky task comprises of prescriber, dispenser and the patient. It is influenced by factors such as prescribing experience, drug cost, availability, dispenser knowledge and patient cultural belief. Objective: Current study aim is to assess the drug prescribing pattern in the inpatient ward of the surgery department at tertiary care teaching hospital using WHO prescribing indicators. Material and Methods: A prospective observational study was carried out after the approval from the institutional ethical committee for a period of six months from February 2019 to July 2019. Data were collected, evaluated and represented using descriptive statics and graph wherever applicable. Result: Total of 190 prescriptions were collected and analyzed using WHO prescribing indicators. An average number of the drug was 5.23%. The percentage of the drug from essential medicine list, generic name and Injectables prescribed was 46.93%, 17.68% and 53.16% respectively. Conclusion: Labelling status of prescribing was not according to standards of WHO prescribing indicators and needs special attention. Such study plays a crucial role in the institution level and helps in preparation of evidence-based modules for rational use of drugs.

scholarly journals A PROSPECTIVE STUDY OF DENTAL DISEASE PATTERN AND DRUG UTILIZATION AT THE DENTAL DEPARTMENT OF A TERTIARY CARE TEACHING HOSPITAL IN EASTERN NEPAL

2003 ◽  
Vol 40 (137) ◽  
pp. 1-5
Author(s):  
G P Rauniyar ◽  
M S Shahanas ◽  
B P Das ◽  
M A Nagarani
Keyword(s):  
Dental Caries ◽  
Drug Utilization ◽  
Drug Combination ◽  
Antimicrobial Agents ◽  
Tertiary Care ◽  
Age Groups ◽  
Fixed Dose ◽  
Prescribing Pattern ◽  
A Prospective Study ◽  
Microbial Agent

To find out the pattern of dental diseases and drug utilization at dental out patientdepartment (OPD) of B.P. Koirala Institute of Health Sciences (BPKIHS), a tertiarycare hospital. A prospective prescription audit was conducted for a period of 10 daysin the dental OPD and the data was analyzed using WHO drug indicators. The totalnumber of prescriptions analyzed were 279. Dental caries (37%), Periodontitis (14%)and chronic gingivitis (11%) were the most common diseases with a maximum incidencebetween the age groups of 9 to 40 years. Mean number of drugs per prescription was2.79. Of the total prescriptions, 223 (79.9%) had 314 antimicrobial agents (AMA)constituting 40.3% of total drugs prescribed. The mean number of antimicrobial agentsper prescription was 1.13. The most commonly prescribed antimicrobial agents wasamoxycillin (33.1%) followed by metronidazole (24.9%), doxycycline (17.2%) andtinidazole (12.7%). Fixed dose drug combination of amoxycillin + cloxacillin (26) andampicillin + cloxacillin (10) were prescribed in 36 of the prescriptions. Povidone iodinegargle (41.2%) was the most commonly prescribed oropharyngeal preparation followedby Chlorhexidine gluconate mouthwash (32.4%). Non- steroidal anti-inflammatoryagents (20.66%), multi-vitamins (19.51%) and oropharyngeal preparations (17.45%)constituted the rest of the drugs prescribed. Diclofenac (60.86%) was the mostcommonly prescribed among NSAIDs and fixed dose drug combination of ibuprofenand paracetamol was prescribed in 19 of the prescriptions. All drugs were given byoral route (except for gentamicin in one prescription) and were prescribed underbrand names. None of the prescriptions had instructions whether the drug should betaken before or after food. The results indicate that dental caries was the most commondental disease, anti-microbial agents were prescribed to majority of the patients andconstituted a little less than half of the total drugs prescribed. Commonly used anti-microbial agent was amoxycillin which in two thirds of the cases was prescribed as anfixed dose drug combination. The high incidence of anti-microbial agent prescribingmay be modified by a feedback to the prescribers.Key words: Dental morbidity, prescribing pattern, drug utilization, dental OPD,antimicrobial agents.

scholarly journals Study of prescribing pattern of antihypertensive drugs in diabetic patients in a tertiary care centre, Vizianagaram, India

2019 ◽  
Vol 8 (6) ◽  
pp. 1192
Author(s):  
Vanathi Elenchezhiyan ◽  
Sachidananda Moorthy ◽  
Sagar M. K. ◽  
Bheemesh Naidu Mattam ◽  
Suresh Babu Sayana
Keyword(s):  
Combination Therapy ◽  
Antihypertensive Drug ◽  
Antihypertensive Drugs ◽  
Tertiary Care ◽  
Prescribing Patterns ◽  
Diabetic Patients ◽  
Care Hospital ◽  
Tertiary Care Centre ◽  
Prescribing Pattern ◽  
Hypertensive Patients

Background: Diabetes mellitus (DM) and Hypertension (HTN) are the two major chronic disorders frequently coexisting, with increased incidence with age. HTN is about twice as common in patients with DM. Prescribing pattern are powerful tools to ascertain the role of drugs in society. There are many variations in prescribing patterns of antihypertensive drugs in patients with HTN and DM. Since these patients requires lifelong treatment it has enormously increased the burden of patients particularly in developing countries like India. Physician needs to be more concerned while choosing drugs for the patients with HTN and DM. In a tertiary care hospital, there is a real need for drug utilization study to determine the appropriate, more safe and effective patterns of drug therapy among diabetic hypertensive patients.Methods: A Cross sectional observational study was conducted in Maharajah’s Institute of Medical Sciences from December 2016 to May 2018. A total of 360 prescriptions of the patients with hypertension and coexisting diabetes were analyzed. The prescriptions prescribed to these patients were collected, assessed and the following parameters were noted. The treatment pattern of different group of drugs for HTN with co-existing DM was evaluated. The intended work was divided into three steps: Step 1: To collect the prescriptions of hypertensive patients with DM. Step 2: To separate the prescriptions prescribing anti hypertensive Drugs. Step 3: To statistically analyze the prescriptions. Relevant information was recorded in a structured proforma & data was evaluated.Results: In this study it was found that 36% of the patients were in the age group of 51-60 years with female preponderance among diabetic hypertensive patients. 77% of patients were treated with single antihypertensive drug and 23% of patients were treated with antihypertensive drug combinations. In monotherapy, telmisartan was most commonly prescribed. In combination therapy, amlodipine and telmisartan followed by amlodipine and atenolol were used.Conclusions: In this study monotherapy was preferred compared to combination therapy and adherence to the JNC 7 guidelines was good except in case of usage of diuretics.

scholarly journals DRUG UTILIZATION PATTERN AND PHARMACOECONOMIC ANALYSIS OF ANTIHYPERTENSIVE DRUGS PRESCRIBED IN SECONDARY CARE HOSPITAL IN GUJARAT, INDIA

2017 ◽  
Vol 10 (3) ◽  
pp. 120 ◽  
Author(s):  
Nilay D Solanki ◽  
Pratik Patel
Keyword(s):  
Drug Utilization ◽  
Medical Cost ◽  
Antihypertensive Drugs ◽  
Generic Drugs ◽  
Pharmacoeconomic Analysis ◽  
Cost Effective ◽  
Fixed Dose ◽  
Care Hospital ◽  
Drug Utilization Study ◽  
Hypertensive Patients

ABSTRACTObjective: Hypertension is the most common condition seen in primary care and leads to myocardial infarction, stroke, renal failure, and death if notdetected early and treated appropriately. A large number of antihypertensive drugs alone or in various combinations are available, and physiciansneed to choose most appropriate drug for a particular patient. Pharmacoeconomic and drug utilization studies at regular intervals help physicians toprescribed rational drugs with high efficacy along with minimal cost.Methods: The prospective observational study was conducted at Seth H. J. Mahagujarat Hospital from July to December 2013. 250 hypertensivepatients, attending medicine outpatient department were included for drug utilization study and 100 hypertensive patients, attending in patientsdepartment were included for pharmacoeconomics analysis during the study period.Result: The most frequently prescribed antihypertensive drug as monotherapy, as combination therapy and in fixed dose combinations was calciumchannel blocker (Amlodipine). Generic drugs showed same efficacy as brand drug, but both drugs were significantly differed in the prize. Among 100inpatients admitted for the hypertensive condition in general ward total of direct medical cost was 65.19% and total of indirect medical cost was34.81%. β-blocker and diuretics were the most effective therapy which is followed by the clonidine, envas (Enalapril), and then, amlodipine.Conclusion: We concluded from this study that use of β-blockers and diuretics were most cost-effective for the hypertensive patients in this study.Keywords: Antihypertensive drugs, Drug utilization study, Pharmacoeconomics analysis. 

scholarly journals Prescribing pattern in Rheumatoid Arthritis patients in a tertiary care teaching hospital

2017 ◽  
Vol 6 (6) ◽  
pp. 1486
Author(s):  
Shakti B. Dutta ◽  
Mirza A. Beg ◽  
Shalu Bawa ◽  
Amanjot Kaur ◽  
Subhash Vishal
Keyword(s):  
Rheumatoid Arthritis ◽  
Drug Use ◽  
Vitamin D3 ◽  
Adult Population ◽  
Tertiary Care ◽  
Essential Medicine ◽  
Brand Names ◽  
Fixed Dose ◽  
Prescribing Pattern ◽  
Calcium Supplements

Background: Rheumatoid arthritis (RA) is associated with joint deformity and significant health care related expenses. This disease affects approximately 1% of the adult population, the prevalence of RA in India is approximately 0.75% and increasing trend has been observed. Irrational prescribing is a common phenomenon around the globe. The drug utilization studies form an important tool for the assessment of rational or irrational prescribing and WHO drug use indicators. Thus keeping this in view the prescribing pattern analysis in RA patients was done.Methods: This prospective study was carried out by the department of pharmacology in medicine OPD of SGRRIM and HS, Dehradun for one year. A total of 450 RA diagnosed patients were included in the study. The diagnosis was made on the basis of clinical assessment and lab parameters as rheumatoid factor and anti-ccp. The collected prescriptions were analyzed by using WHO drug use indicators.Results: Total of 450 prescriptions was analyzed. 378 (84%) were females and 72 (16%) were males. Most commonly presenting age group was 31-60 years 276 (61.33%). Family history and RA factor was positive in 168 (37.33%) and 318 (70.67%) patients respectively. Anti-ccp was raised in 408 (90.67%) patients. The comorbid conditions were type-2 diabetes mellitus 72 (16%), hypertension 48 (10.67%), hypothyroidism 36 (8%) and other associated illness 54 (12%). Total of 1655 drugs were prescribed during the study period. The prescribed drugs were disease modifying anti-rheumatic drugs (DMARDs) 582 (35.18%), vitamin-D3 and calcium supplements 320 (19.34%), analgesics 311 (18.80%), antacids 204 (12.33%), others 238(14.38%). 437 (26.40%) fixed dose combinations (FDCs), 3.67 drugs per prescription, 1145 (69.18%) drugs by brand names and 1161 (70.15%) drugs from the National List of Essential Medicine (NLEM) 2015 were prescribed.Conclusions: Drug prescribing pattern depicts that most commonly prescribed were DMARDs, vitamin-D3 and calcium supplements and analgesics. Most of the drugs were prescribed from NLEM 2015.

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